{"id":9441,"date":"2026-01-27T20:42:09","date_gmt":"2026-01-27T18:42:09","guid":{"rendered":"https:\/\/mikrobiologikolamia.gr\/staging\/?p=9441"},"modified":"2026-01-27T21:03:48","modified_gmt":"2026-01-27T19:03:48","slug":"exetasi-apoe","status":"publish","type":"post","link":"https:\/\/mikrobiologikolamia.gr\/staging\/exetasi-apoe\/","title":{"rendered":"\u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 ApoE (\u0391\u03c0\u03bf\u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u0395): \u0393\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u0388\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b3\u03b9\u03b1 Alzheimer &#038; \u039a\u03b1\u03c1\u03b4\u03b9\u03ac"},"content":{"rendered":"<h1 style=\"font-size: 30px; font-weight: 800; margin: 18px 0 6px; line-height: 1.2;\">\u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 ApoE (\u0391\u03c0\u03bf\u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u0395): \u0393\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03b3\u03b9\u03b1 \u039a\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u039a\u03af\u03bd\u03b4\u03c5\u03bd\u03bf &amp; \u039d\u03cc\u03c3\u03bf Alzheimer<\/h1>\n<p style=\"font-size: 14px; color: #6b7280; margin: 6px 0 12px;\">\u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7:<br \/>\n<time datetime=\"2026-01-27\">27 \u0399\u03b1\u03bd\u03bf\u03c5\u03b1\u03c1\u03af\u03bf\u03c5 2026<\/time><\/p>\n<p><!-- ==================== MINI INFOBOX ==================== --><\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; font-size: 14px; line-height: 1.6;\"><strong>\u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u03c3\u03cd\u03bd\u03bf\u03c8\u03b7:<\/strong> \u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 <strong>ApoE \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2<\/strong> \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03b9 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c4\u03b7\u03c2 \u03b1\u03c0\u03bf\u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 \u0395 \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 <strong>\u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf<\/strong> \u03ba\u03b1\u03b9 <strong>Alzheimer<\/strong>. \u0393\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 Real-Time PCR \u03c3\u03b5 \u03bf\u03bb\u03b9\u03ba\u03cc \u03b1\u03af\u03bc\u03b1 (EDTA) \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 <strong>\u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7\u03c2<\/strong>, \u03cc\u03c7\u03b9 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7.<\/div>\n<p><!-- ==================== TABLE OF CONTENTS ==================== --><\/p>\n<nav id=\"toc\" style=\"background: #f9fafb; border: 1px solid #e5e7eb; border-radius: 14px; padding: 16px 18px; margin: 22px 0;\" aria-label=\"\u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1\"><strong>\ud83d\udcd1 \u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1<\/strong><\/p>\n<ol style=\"margin: 10px 0 0 18px; line-height: 1.9;\">\n<li><a href=\"#sec1\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 ApoE<\/a><\/li>\n<li><a href=\"#sec2\">\u03a4\u03b9 \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 ApoE<\/a><\/li>\n<li><a href=\"#sec3\">\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1<\/a><\/li>\n<li><a href=\"#sec4\">\u0399\u03c3\u03bf\u03bc\u03bf\u03c1\u03c6\u03ad\u03c2 ApoE (E2, E3, E4)<\/a><\/li>\n<li><a href=\"#sec5\">ApoE \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf\u03c2<\/a><\/li>\n<li><a href=\"#sec6\">ApoE \u03ba\u03b1\u03b9 \u03bd\u03cc\u03c3\u03bf\u03c2 Alzheimer<\/a><\/li>\n<li><a href=\"#sec7\">\u03a0\u03cc\u03c4\u03b5 \u03ad\u03c7\u03b5\u03b9 \u03bd\u03cc\u03b7\u03bc\u03b1 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/a><\/li>\n<li><a href=\"#sec8\">\u03a0\u03ce\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/a><\/li>\n<li><a href=\"#sec9\">\u0394\u03b5\u03af\u03b3\u03bc\u03b1 \u2013 \u039c\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 \u2013 \u0391\u03be\u03b9\u03bf\u03c0\u03b9\u03c3\u03c4\u03af\u03b1<\/a><\/li>\n<li><a href=\"#sec10\">\u03a4\u03b9\u03bc\u03ad\u03c2 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 &amp; \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1<\/a><\/li>\n<li><a href=\"#sec11\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 ApoE3\/E3<\/a><\/li>\n<li><a href=\"#sec12\">\u03a0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03af \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2<\/a><\/li>\n<li><a href=\"#sec13\">\u03a3\u03c5\u03c7\u03bd\u03ac \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03bb\u03ac\u03b8\u03b7<\/a><\/li>\n<li><a href=\"#sec14\">\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/a><\/li>\n<li><a href=\"#faq\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/a><\/li>\n<li><a href=\"#cta\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd<\/a><\/li>\n<li><a href=\"#bib\">\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/a><\/li>\n<\/ol>\n<\/nav>\n<hr style=\"border: none; border-top: 2px solid #d1d5db; margin: 18px 0;\" \/>\n<p><!-- ==================== SECTION 1 ==================== --><\/p>\n<h2 id=\"sec1\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">1<\/span><\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 ApoE<\/span><\/h2>\n<p><strong>\u03a3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7:<\/strong> \u0397 ApoE \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u03c0\u03bf\u03c5 \u03c1\u03c5\u03b8\u03bc\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03cc\u03c3\u03bf \u03c4\u03bf\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03b3\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5.<\/p>\n<p>\u0397 <strong>\u03b1\u03c0\u03bf\u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u0395 (ApoE)<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ae \u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u03c4\u03bf\u03c5 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c3\u03c5\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03c4\u03bf \u03ae\u03c0\u03b1\u03c1 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03c2 \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7\u03c2, \u03c4\u03c9\u03bd \u03c4\u03c1\u03b9\u03b3\u03bb\u03c5\u03ba\u03b5\u03c1\u03b9\u03b4\u03af\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03bb\u03b5\u03b9\u03bc\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03ce\u03bd \u03c0\u03c1\u03bf\u03c2 \u03c4\u03bf \u03ae\u03c0\u03b1\u03c1 \u03b3\u03b9\u03b1 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03bc\u03ac\u03ba\u03c1\u03c5\u03bd\u03c3\u03b7.<\/p>\n<p>\u03a0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac, \u03b7 ApoE \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c9\u03c2 \u03ad\u03bd\u03b1 \u03b5\u03af\u03b4\u03bf\u03c2 \u00ab\u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03bf\u03cd \u03ba\u03bb\u03b5\u03b9\u03b4\u03b9\u03bf\u03cd\u00bb: \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03b5\u03b9 \u03c3\u03c4\u03b1 \u03c3\u03c9\u03bc\u03b1\u03c4\u03af\u03b4\u03b9\u03b1 \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd (\u03c7\u03c5\u03bb\u03bf\u03bc\u03b9\u03ba\u03c1\u03ac, VLDL remnants \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b9\u03c0\u03b1) \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03b5\u03af\u03c2 \u03c4\u03b7\u03c2 \u03b5\u03c0\u03b9\u03c6\u03ac\u03bd\u03b5\u03b9\u03b1\u03c2 \u03c4\u03c9\u03bd \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd, \u03cc\u03c0\u03c9\u03c2 \u03bf LDL-\u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03bf LRP1, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03bc\u03b1\u03ba\u03c1\u03cd\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03af\u03b1.<\/p>\n<p>\u038c\u03c4\u03b1\u03bd \u03b1\u03c5\u03c4\u03cc\u03c2 \u03bf \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b4\u03b5\u03bd \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac, \u03b1\u03c5\u03be\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c4\u03b1 \u03bb\u03b5\u03b3\u03cc\u03bc\u03b5\u03bd\u03b1 <strong>\u03b1\u03b8\u03b7\u03c1\u03bf\u03b3\u03cc\u03bd\u03b1 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b9\u03c0\u03b1<\/strong> \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1 \u2014 \u03c3\u03c9\u03bc\u03b1\u03c4\u03af\u03b4\u03b9\u03b1 \u03c0\u03bb\u03bf\u03cd\u03c3\u03b9\u03b1 \u03c3\u03b5 \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b5\u03b9\u03c3\u03b4\u03cd\u03bf\u03c5\u03bd \u03c3\u03c4\u03bf \u03c4\u03bf\u03af\u03c7\u03c9\u03bc\u03b1 \u03c4\u03c9\u03bd \u03b1\u03b3\u03b3\u03b5\u03af\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03bf\u03c5\u03bd \u03c3\u03c4\u03bf\u03bd \u03c3\u03c7\u03b7\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03cc \u03b1\u03b8\u03b7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03bb\u03ac\u03ba\u03b1\u03c2.<\/p>\n<p>\u03a0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1, \u03b7 ApoE \u03ad\u03c7\u03b5\u03b9 \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03bf <strong>\u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03cc \u03bd\u03b5\u03c5\u03c1\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1<\/strong>. \u0395\u03ba\u03b5\u03af \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03ae\u03c0\u03b1\u03c1, \u03b1\u03bb\u03bb\u03ac \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf\u03c0\u03b9\u03ba\u03ac \u03b1\u03c0\u03cc \u03b1\u03c3\u03c4\u03c1\u03bf\u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b3\u03bb\u03bf\u03af\u03b1. \u03a3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03ba\u03b1\u03c4\u03b1\u03bd\u03bf\u03bc\u03ae \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7\u03c2, \u03c6\u03c9\u03c3\u03c6\u03bf\u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd \u03ba\u03b1\u03b9 \u03bb\u03b9\u03c0\u03b1\u03c1\u03ce\u03bd \u03bf\u03be\u03ad\u03c9\u03bd \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03bd\u03b5\u03c5\u03c1\u03ce\u03bd\u03c9\u03bd, \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03b1\u03c0\u03c4\u03b9\u03ba\u03ae \u03c0\u03bb\u03b1\u03c3\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03b5\u03c0\u03b9\u03b4\u03b9\u03cc\u03c1\u03b8\u03c9\u03c3\u03b7\u03c2 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03c4\u03c1\u03b1\u03c5\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae.<\/p>\n<p>\u0397 \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7 \u03c3\u03c4\u03bf\u03bd \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf \u03b4\u03b5\u03bd \u03c0\u03b5\u03c1\u03bd\u03ac \u03b5\u03bb\u03b5\u03cd\u03b8\u03b5\u03c1\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b1\u03af\u03bc\u03b1, \u03b5\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2 \u03b7 \u03c4\u03bf\u03c0\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03b7\u03c2 ApoE \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03bd\u03b5\u03c5\u03c1\u03c9\u03bd\u03b9\u03ba\u03ce\u03bd \u03bc\u03b5\u03bc\u03b2\u03c1\u03b1\u03bd\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bd\u03ac\u03c8\u03b5\u03c9\u03bd. \u0394\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03c5\u03bd\u03b4\u03b5\u03b8\u03b5\u03af \u03bc\u03b5 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03ba\u03ac\u03b8\u03b1\u03c1\u03c3\u03b7 \u03b2-\u03b1\u03bc\u03c5\u03bb\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae.<\/p>\n<p>\u039c\u03b5 \u03b1\u03c0\u03bb\u03ac \u03bb\u03cc\u03b3\u03b9\u03b1: \u03b7 ApoE \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b1 \u03c4\u03bf\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc \u03c4\u03c9\u03bd \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03c6\u03ad\u03c1\u03b5\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03c9\u03bd\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1 \u03c3\u03c4\u03bf\u03bd \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf. \u0391\u03c5\u03c4\u03cc \u03b5\u03be\u03b7\u03b3\u03b5\u03af \u03b3\u03b9\u03b1\u03c4\u03af \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03b9 \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03b9 \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c4\u03cc\u03c3\u03bf \u03bc\u03b5 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03bc\u03b5 \u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03ad\u03ba\u03c0\u03c4\u03c9\u03c3\u03b7 \u03ae \u03ac\u03bd\u03bf\u03b9\u03b1.<\/p>\n<p>\u0393\u03b9\u03b1 \u03c4\u03bf\u03bd \u03bb\u03cc\u03b3\u03bf \u03b1\u03c5\u03c4\u03cc, \u03b7 ApoE \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03ad\u03bd\u03b1\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03bf\u03c5\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03ad\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03c3\u03b5 \u03b4\u03cd\u03bf \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf\u03c5\u03c2 \u03c4\u03bf\u03bc\u03b5\u03af\u03c2 \u03c4\u03b7\u03c2 \u03c3\u03cd\u03b3\u03c7\u03c1\u03bf\u03bd\u03b7\u03c2 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2: \u03c4\u03b7\u03bd \u03b1\u03b8\u03b7\u03c1\u03bf\u03c3\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf Alzheimer.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5:<\/strong><br \/>\n\u0397 ApoE \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c9\u03c2 \u00ab\u03bc\u03b5\u03c3\u03bf\u03bb\u03b1\u03b2\u03b7\u03c4\u03ae\u03c2\u00bb \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd \u03c3\u03c4\u03bf \u03c3\u03ce\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf. \u0394\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03bf\u03af \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03b9 \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03bf\u03cd\u03bd \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03bf\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03bd\u03cc\u03c3\u03bf, \u03b1\u03bb\u03bb\u03ac \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd \u03c4\u03bf\u03bd \u03bc\u03b1\u03ba\u03c1\u03bf\u03c0\u03c1\u03cc\u03b8\u03b5\u03c3\u03bc\u03bf \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03ba\u03b1\u03b9 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf.<\/div>\n<p><!-- ==================== SECTION 2 ==================== --><\/p>\n<h2 id=\"sec2\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">2<\/span><\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 ApoE<\/span><\/h2>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03bf\u03bd\u03bf\u03c4\u03cd\u03c0\u03bf\u03c5 ApoE \u03b1\u03bd\u03b1\u03bb\u03cd\u03b5\u03b9 \u03b4\u03cd\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03bf\u03bb\u03c5\u03bc\u03bf\u03c1\u03c6\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 APOE: \u03c4\u03bf\u03bd <strong>rs429358<\/strong> (\u03b8\u03ad\u03c3\u03b7 112 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03b9\u03ba\u03bf\u03cd \u03bc\u03bf\u03c1\u03af\u03bf\u03c5) \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd <strong>rs7412<\/strong> (\u03b8\u03ad\u03c3\u03b7 158). \u039f\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03bf\u03af \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03bf\u03af \u03b1\u03c5\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03c3\u03b7\u03bc\u03b5\u03af\u03c9\u03bd \u03ba\u03b1\u03b8\u03bf\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03c0\u03bf\u03b9\u03b1 \u03b9\u03c3\u03bf\u03bc\u03bf\u03c1\u03c6\u03ae ApoE \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03b9 \u03bf \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2.<\/p>\n<p>\u039c\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b4\u03cd\u03bf \u03c3\u03b7\u03bc\u03b5\u03af\u03b1, \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b1\u03be\u03b9\u03bd\u03bf\u03bc\u03b5\u03af \u03c4\u03bf \u03ac\u03c4\u03bf\u03bc\u03bf \u03c3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03c0\u03b9\u03b8\u03b1\u03bd\u03bf\u03cd\u03c2 \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c5\u03c2, \u03cc\u03c0\u03c9\u03c2 <strong>E3\/E3<\/strong>, <strong>E3\/E4<\/strong>, <strong>E2\/E3<\/strong>, <strong>E4\/E4<\/strong> \u03ba.\u03ac.<\/p>\n<p>\u0395\u03b4\u03ce \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03bf \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9 \u03ba\u03b1\u03c4\u03b1\u03bd\u03bf\u03b7\u03c4\u03cc \u03cc\u03c4\u03b9 \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 <strong>\u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7\u03c2<\/strong> \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03bd\u03cc\u03c3\u03bf\u03c5. \u039f \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c0\u03b5\u03b9 \u03bc\u03b5 \u03b2\u03b5\u03b2\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b9 \u03b8\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b5\u03af \u03c3\u03c4\u03bf \u03bc\u03ad\u03bb\u03bb\u03bf\u03bd\u00b7 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03c4\u03b9\u03c2 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2.<\/p>\n<p>\u0394\u03b7\u03bb\u03b1\u03b4\u03ae, \u03ad\u03bd\u03b1\u03c2 \u00ab\u03b4\u03c5\u03c3\u03bc\u03b5\u03bd\u03ae\u03c2\u00bb \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 (\u03cc\u03c0\u03c9\u03c2 \u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 ApoE4) \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf\u03c2 \u03b8\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03b5\u03b9 \u03c5\u03c0\u03bf\u03c7\u03c1\u03b5\u03c9\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 \u03ae Alzheimer. \u0391\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b1, \u03ad\u03bd\u03b1\u03c2 \u00ab\u03bf\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03bf\u03c2\u00bb \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03b4\u03b5\u03bd \u03b5\u03b3\u03b3\u03c5\u03ac\u03c4\u03b1\u03b9 \u03c0\u03bb\u03ae\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c3\u03af\u03b1.<\/p>\n<p>\u03a4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c3\u03c5\u03bd\u03b5\u03ba\u03c4\u03b9\u03bc\u03ac\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bc\u03b5:<\/p>\n<p>\u2022 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c6\u03cd\u03bb\u03bf<br \/>\n\u2022 \u03bb\u03b9\u03c0\u03b9\u03b4\u03b1\u03b9\u03bc\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb (LDL, non-HDL, \u03c4\u03c1\u03b9\u03b3\u03bb\u03c5\u03ba\u03b5\u03c1\u03af\u03b4\u03b9\u03b1, \u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a))<br \/>\n\u2022 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c0\u03af\u03b5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2<br \/>\n\u2022 \u03c4\u03c1\u03cc\u03c0\u03bf \u03b6\u03c9\u03ae\u03c2 (\u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae, \u03ac\u03c3\u03ba\u03b7\u03c3\u03b7, \u03ba\u03ac\u03c0\u03bd\u03b9\u03c3\u03bc\u03b1)<br \/>\n\u2022 \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ae \u03ac\u03bd\u03bf\u03b9\u03b1\u03c2<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03ac\u03be\u03b7, \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 ApoE \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03bf <strong>\u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/strong>. \u0392\u03bf\u03b7\u03b8\u03ac \u03c4\u03bf\u03bd \u03b9\u03b1\u03c4\u03c1\u03cc \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03cc\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c0\u03bf\u03c4\u03ad \u03c9\u03c2 \u03b1\u03c5\u03c4\u03cc\u03bd\u03bf\u03bc\u03bf \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03cc \u03c4\u03b5\u03c3\u03c4.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5:<\/strong><br \/>\n\u039f \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 ApoE \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 <strong>\u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7<\/strong> \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \u0397 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03b4\u03b9\u03b1\u03bc\u03bf\u03c1\u03c6\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03bb\u03b9\u03c0\u03af\u03b4\u03b9\u03b1, \u03c4\u03bf\u03bd \u03c4\u03c1\u03cc\u03c0\u03bf \u03b6\u03c9\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c5\u03bd\u03bf\u03b4\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5.<\/div>\n<p><!-- ==================== SECTION 3 ==================== --><\/p>\n<h2 id=\"sec3\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">3<\/span><\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1<\/span><\/h2>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 ApoE \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c9\u03c2 <strong>\u03c3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03bf<\/strong> \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03c9\u03c2 \u03b1\u03c5\u03c4\u03cc\u03bd\u03bf\u03bc\u03bf \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03cc \u03c4\u03b5\u03c3\u03c4.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03ac\u03be\u03b7 \u03b1\u03be\u03b9\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b3\u03b9\u03b1:<\/p>\n<p>\u2022 \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 <strong>\u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/strong> \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03b4\u03c5\u03c3\u03bb\u03b9\u03c0\u03b9\u03b4\u03b1\u03b9\u03bc\u03af\u03b1 \u03ae \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03c3\u03c4\u03b5\u03c6\u03b1\u03bd\u03b9\u03b1\u03af\u03b1 \u03bd\u03cc\u03c3\u03bf<br \/>\n\u2022 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 <strong>\u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7\u03c2<\/strong> \u03b3\u03b9\u03b1 \u03bd\u03cc\u03c3\u03bf Alzheimer, \u03b9\u03b4\u03af\u03c9\u03c2 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc<br \/>\n\u2022 \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 <strong>\u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03c9\u03bd \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2<\/strong> (\u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae, \u03ac\u03c3\u03ba\u03b7\u03c3\u03b7, \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd, \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7)<\/p>\n<p>\u0397 \u03b1\u03be\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03b5\u03ba\u03c4\u03b9\u03bc\u03ac\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03bf\u03cd\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 LDL-\u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7, non-HDL, \u03c4\u03c1\u03b9\u03b3\u03bb\u03c5\u03ba\u03b5\u03c1\u03af\u03b4\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a), \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 (\u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c0\u03af\u03b5\u03c3\u03b7, \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03bc\u03ac\u03b6\u03b1\u03c2 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03ba\u03ac\u03c0\u03bd\u03b9\u03c3\u03bc\u03b1, \u03c3\u03b1\u03ba\u03c7\u03b1\u03c1\u03ce\u03b4\u03b7\u03c2 \u03b4\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7\u03c2).<\/p>\n<p>\u03a3\u03c4\u03bf \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf, \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 ApoE \u03b4\u03b5\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 Alzheimer, \u03b1\u03bb\u03bb\u03ac \u03c9\u03c2 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03ae\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5, \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03bc\u03b5 \u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7, \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03b2\u03b9\u03bf\u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2.<\/p>\n<p>\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u00ab\u03bf\u03c1\u03b9\u03b1\u03ba\u03ac\u00bb \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5, \u03cc\u03c0\u03bf\u03c5 \u03b7 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03c6\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c0\u03b9\u03bf \u03b5\u03bd\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03ae \u03c3\u03c4\u03b5\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7.<\/p>\n<p>\u0394\u03b5\u03bd \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 screening \u03b3\u03b5\u03bd\u03b9\u03ba\u03bf\u03cd \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03bf\u03cd. \u0395\u03c6\u03b1\u03c1\u03bc\u03cc\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1, \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1.<\/p>\n<p><!-- ==================== SECTION 4 ==================== --><\/p>\n<h2 id=\"sec4\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">4<\/span><\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0399\u03c3\u03bf\u03bc\u03bf\u03c1\u03c6\u03ad\u03c2 ApoE (E2, E3, E4)<\/span><\/h2>\n<p>\u03a3\u03c4\u03bf\u03bd \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03bf \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03cc \u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03b5\u03af \u03c4\u03c1\u03b5\u03b9\u03c2 \u03ba\u03cd\u03c1\u03b9\u03b5\u03c2 \u03b9\u03c3\u03bf\u03bc\u03bf\u03c1\u03c6\u03ad\u03c2 \u03c4\u03b7\u03c2 ApoE, \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03ba\u03b1\u03c4\u03ac \u03ad\u03bd\u03b1 \u03bc\u03cc\u03bd\u03bf \u03b1\u03bc\u03b9\u03bd\u03bf\u03be\u03cd, \u03b1\u03bb\u03bb\u03ac \u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac.<\/p>\n<p><strong>ApoE3<\/strong> (Cys112 \/ Arg158) \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b9\u03c3\u03bf\u03bc\u03bf\u03c1\u03c6\u03ae \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ac \u00ab\u03bf\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03b7\u00bb. \u039f\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf\u03b9 \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf\u03b9 \u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03c4\u03bf\u03c5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03bf\u03bd \u03ad\u03bd\u03b1 \u03b1\u03bd\u03c4\u03af\u03b3\u03c1\u03b1\u03c6\u03bf ApoE3.<\/p>\n<p><strong>ApoE2<\/strong> (Cys112 \/ Cys158) \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03b9 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03cd\u03bd\u03b4\u03b5\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 LDL \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03b5\u03af\u03c2. \u0391\u03c5\u03c4\u03cc \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7 \u03c5\u03c0\u03bf\u03bb\u03b5\u03b9\u03bc\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03ce\u03bd \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1. \u03a3\u03b5 \u03bc\u03b9\u03ba\u03c1\u03cc \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03ac\u03bb\u03bb\u03bf\u03b9 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2, \u03b1\u03c5\u03c4\u03cc \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03c5\u03c0\u03b5\u03c1\u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03b1\u03b9\u03bc\u03af\u03b1 \u03c4\u03cd\u03c0\u03bf\u03c5 \u0399\u0399\u0399, \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b1 remnant \u03c3\u03c9\u03bc\u03b1\u03c4\u03af\u03b4\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b1\u03b8\u03b7\u03c1\u03bf\u03c3\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7\u03c2.<\/p>\n<p><strong>ApoE4<\/strong> (Arg112 \/ Arg158) \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03c4\u03c1\u03b9\u03c3\u03b4\u03b9\u03ac\u03c3\u03c4\u03b1\u03c4\u03b7 \u03b4\u03bf\u03bc\u03ae, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03cc\u03c3\u03bf \u03c4\u03bf\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc \u03c4\u03c9\u03bd \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c3\u03c4\u03bf\u03bd \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf. \u03a3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03c6\u03ad\u03c1\u03b5\u03b9\u03b1 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 LDL \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c3\u03c4\u03b1 \u03ba\u03bf\u03c1\u03b5\u03c3\u03bc\u03ad\u03bd\u03b1 \u03bb\u03b9\u03c0\u03b1\u03c1\u03ac. \u03a3\u03c4\u03bf \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03cc \u03bd\u03b5\u03c5\u03c1\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03ba\u03ac\u03b8\u03b1\u03c1\u03c3\u03b7 \u03b2-\u03b1\u03bc\u03c5\u03bb\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae.<\/p>\n<p>\u0397 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 ApoE4 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b1\u03b8\u03b7\u03c1\u03bf\u03c3\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03cc\u03c3\u03bf\u03c5 Alzheimer, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b4\u03cd\u03bf \u03b1\u03bd\u03c4\u03af\u03b3\u03c1\u03b1\u03c6\u03b1 (E4\/E4). \u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7, \u03b7 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ae \u03ad\u03ba\u03b2\u03b1\u03c3\u03b7 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c0\u03b5\u03c1\u03b9\u03b2\u03b1\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b9\u03bc\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2.<\/p>\n<p>\u0393\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc \u03ba\u03b1\u03b9 \u03b7 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c4\u03c9\u03bd \u03b9\u03c3\u03bf\u03bc\u03bf\u03c1\u03c6\u03ce\u03bd \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03c4\u03bf \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03b1\u03c0\u03bf\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b1.<\/p>\n<p><!-- ==================== SECTION 5 ==================== --><\/p>\n<h2 id=\"sec5\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">5<\/span><\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">ApoE \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf\u03c2<\/span><\/h2>\n<p>\u0397 ApoE \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03ae \u03c4\u03b7\u03c2 \u03ba\u03ac\u03b8\u03b1\u03c1\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03b1\u03b8\u03b7\u03c1\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03c4\u03b1\u03bb\u03bf\u03af\u03c0\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03af\u03b1. \u038c\u03c4\u03b1\u03bd \u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03ae \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c5\u03be\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c4\u03b1 \u03bb\u03b5\u03b3\u03cc\u03bc\u03b5\u03bd\u03b1 remnants (\u03c5\u03c0\u03bf\u03bb\u03b5\u03af\u03bc\u03bc\u03b1\u03c4\u03b1 VLDL \u03ba\u03b1\u03b9 \u03c7\u03c5\u03bb\u03bf\u03bc\u03b9\u03ba\u03c1\u03ce\u03bd), \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c0\u03bb\u03bf\u03cd\u03c3\u03b9\u03b1 \u03c3\u03b5 \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b5\u03b9\u03c3\u03b4\u03cd\u03bf\u03c5\u03bd \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03c3\u03c4\u03bf \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03c4\u03bf\u03af\u03c7\u03c9\u03bc\u03b1.<\/p>\n<p>\u0391\u03c5\u03c4\u03ae \u03b7 \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7 \u03c5\u03c0\u03bf\u03bb\u03b5\u03b9\u03bc\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03b4\u03af\u03c9\u03bd \u03b5\u03c0\u03b9\u03c4\u03b1\u03c7\u03cd\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03c3\u03c7\u03b7\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03cc \u03b1\u03b8\u03b7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03bb\u03ac\u03ba\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03ac\u03b3\u03b5\u03b9 \u03c4\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03c3\u03c4\u03bf \u03b5\u03bd\u03b4\u03bf\u03b8\u03ae\u03bb\u03b9\u03bf, \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b9\u03c2 \u03c0\u03c1\u03bf\u03cb\u03c0\u03bf\u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03b3\u03b9\u03b1 \u03c3\u03c4\u03b5\u03c6\u03b1\u03bd\u03b9\u03b1\u03af\u03b1 \u03bd\u03cc\u03c3\u03bf, \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ac \u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03ba\u03ac \u03b5\u03c0\u03b5\u03b9\u03c3\u03cc\u03b4\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c6\u03b5\u03c1\u03b9\u03ba\u03ae \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1.<\/p>\n<p>\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c6\u03bf\u03c1\u03b5\u03af\u03c2 \u03c4\u03b7\u03c2 \u03b9\u03c3\u03bf\u03bc\u03bf\u03c1\u03c6\u03ae\u03c2 <strong>ApoE4<\/strong>, \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 LDL-\u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ae \u03c0\u03c1\u03cc\u03c3\u03bb\u03b7\u03c8\u03b7 \u03ba\u03bf\u03c1\u03b5\u03c3\u03bc\u03ad\u03bd\u03c9\u03bd \u03bb\u03b9\u03c0\u03b1\u03c1\u03ce\u03bd. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03af\u03b4\u03b9\u03bf \u03b4\u03b9\u03b1\u03b9\u03c4\u03bf\u03bb\u03cc\u03b3\u03b9\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b4\u03c5\u03c3\u03bc\u03b5\u03bd\u03ad\u03c3\u03c4\u03b5\u03c1\u03b7 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b1 \u03bb\u03b9\u03c0\u03af\u03b4\u03b9\u03b1 \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03ac\u03bb\u03bb\u03c9\u03bd \u03b3\u03bf\u03bd\u03bf\u03c4\u03cd\u03c0\u03c9\u03bd.<\/p>\n<p>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac, \u03b1\u03c5\u03c4\u03cc \u03bc\u03b5\u03c4\u03b1\u03c6\u03c1\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03c3\u03c4\u03b5\u03c6\u03b1\u03bd\u03b9\u03b1\u03af\u03b1\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5, \u03b9\u03b4\u03af\u03c9\u03c2 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03bf\u03b9 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03ba\u03ac\u03c0\u03bd\u03b9\u03c3\u03bc\u03b1, \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7, \u03c3\u03b1\u03ba\u03c7\u03b1\u03c1\u03ce\u03b4\u03b7\u03c2 \u03b4\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7\u03c2 \u03ae \u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b6\u03c9\u03ae.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7, \u03b7 \u03b3\u03bd\u03ce\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c5 ApoE \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9:<\/p>\n<p>\u2022 \u03c3\u03c4\u03b7\u03bd \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf\u03c5 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<br \/>\n\u2022 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b9\u03bf \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ae \u03ba\u03b1\u03b8\u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b7 (\u03b9\u03b4\u03af\u03c9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc \u03ba\u03bf\u03c1\u03b5\u03c3\u03bc\u03ad\u03bd\u03c9\u03bd \u03bb\u03b9\u03c0\u03b1\u03c1\u03ce\u03bd)<br \/>\n\u2022 \u03c3\u03c4\u03b7 \u03c3\u03c4\u03b5\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd<br \/>\n\u2022 \u03ba\u03b1\u03b9, \u03cc\u03c0\u03bf\u03c5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9, \u03c3\u03c4\u03b7\u03bd \u03c0\u03b9\u03bf \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7<\/p>\n<p>\u0394\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03bf\u03c5\u03c2 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03bf\u03cd\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2, \u03b1\u03bb\u03bb\u03ac \u03c0\u03c1\u03bf\u03c3\u03b8\u03ad\u03c4\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03af\u03ba\u03b5\u03c5\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u039a\u03b1\u03c1\u03b4\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b5\u03af\u03c9\u03c3\u03b7:<\/strong><br \/>\n\u03a3\u03b5 \u03c6\u03bf\u03c1\u03b5\u03af\u03c2 ApoE4, \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 LDL \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03b8\u03b7\u03c1\u03bf\u03b3\u03cc\u03bd\u03bf \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7. \u0397 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae, \u03b2\u03ac\u03c1\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03bb\u03b9\u03c0\u03af\u03b4\u03b9\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1.<\/div>\n<p><!-- ==================== SECTION 6 ==================== --><\/p>\n<h2 id=\"sec6\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">6<\/span><\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">ApoE \u03ba\u03b1\u03b9 \u03bd\u03cc\u03c3\u03bf\u03c2 Alzheimer<\/span><\/h2>\n<p>\u03a3\u03c4\u03bf\u03bd \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf, \u03b7 ApoE \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03bc\u03ac\u03ba\u03c1\u03c5\u03bd\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b2-\u03b1\u03bc\u03c5\u03bb\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03ba\u03b5\u03c1\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03c9\u03bd \u03bd\u03b5\u03c5\u03c1\u03c9\u03bd\u03b9\u03ba\u03ce\u03bd \u03bc\u03b5\u03bc\u03b2\u03c1\u03b1\u03bd\u03ce\u03bd. \u0397 \u03b9\u03c3\u03bf\u03bc\u03bf\u03c1\u03c6\u03ae <strong>ApoE4<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03b5 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03b4\u03b9\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b5\u03c2, \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b5\u03bd\u03b1\u03c0\u03cc\u03b8\u03b5\u03c3\u03b7 \u03b1\u03bc\u03c5\u03bb\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2, \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03c4\u03bf\u03c5 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03ba\u03bf\u03cd \u03c6\u03c1\u03b1\u03b3\u03bc\u03bf\u03cd \u03ba\u03b1\u03b9 \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2.<\/p>\n<p>\u0391\u03c5\u03c4\u03bf\u03af \u03bf\u03b9 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03af \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03bf\u03af \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03b8\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 Alzheimer. \u03a9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1, \u03bf\u03b9 \u03c6\u03bf\u03c1\u03b5\u03af\u03c2 ApoE4 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bd\u03c9\u03c1\u03af\u03c4\u03b5\u03c1\u03b7 \u03ad\u03bd\u03b1\u03c1\u03be\u03b7 \u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ad\u03ba\u03c0\u03c4\u03c9\u03c3\u03b7\u03c2.<\/p>\n<p>\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03bd\u03b1 \u03c4\u03bf\u03bd\u03b9\u03c3\u03c4\u03b5\u03af \u03cc\u03c4\u03b9 \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 <strong>\u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03cc<\/strong> \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03b1\u03c0\u03cc\u03bb\u03c5\u03c4\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf. \u03a0\u03bf\u03bb\u03bb\u03bf\u03af \u03c6\u03bf\u03c1\u03b5\u03af\u03c2 ApoE4 \u03b4\u03b5\u03bd \u03b8\u03b1 \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03be\u03bf\u03c5\u03bd \u03c0\u03bf\u03c4\u03ad Alzheimer, \u03b5\u03bd\u03ce \u03b1\u03c1\u03ba\u03b5\u03c4\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 Alzheimer \u03b4\u03b5\u03bd \u03c6\u03ad\u03c1\u03bf\u03c5\u03bd ApoE4.<\/p>\n<p>\u039f \u03c4\u03b5\u03bb\u03b9\u03ba\u03cc\u03c2 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b9\u03bc\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2, \u03cc\u03c0\u03c9\u03c2:<\/p>\n<p>\u2022 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03b5\u03ba\u03c0\u03b1\u03af\u03b4\u03b5\u03c5\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b5\u03c6\u03b5\u03b4\u03c1\u03b5\u03af\u03b1<br \/>\n\u2022 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ae \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1<br \/>\n\u2022 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1<br \/>\n\u2022 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b1\u03ba\u03c7\u03ac\u03c1\u03bf\u03c5<br \/>\n\u2022 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03cd\u03c0\u03bd\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb<\/p>\n<p>\u039c\u03b5 \u03ac\u03bb\u03bb\u03b1 \u03bb\u03cc\u03b3\u03b9\u03b1, \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03ad\u03ba\u03b2\u03b1\u03c3\u03b7 \u03b4\u03b9\u03b1\u03bc\u03bf\u03c1\u03c6\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf \u03b2\u03b1\u03b8\u03bc\u03cc \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03c4\u03c1\u03cc\u03c0\u03bf \u03b6\u03c9\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b5\u03af\u03c9\u03c3\u03b7:<\/strong><br \/>\n\u0397 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 ApoE4 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf Alzheimer, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ae \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1, \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c4\u03c9\u03bd \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd, \u03b7 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c0\u03af\u03b5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7.<\/div>\n<p><!-- ==================== SECTION 7 ==================== --><\/p>\n<h2 id=\"sec7\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">7<\/span><\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03cc\u03c4\u03b5 \u03ad\u03c7\u03b5\u03b9 \u03bd\u03cc\u03b7\u03bc\u03b1 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9<\/span><\/h2>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 ApoE \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03bf\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bc\u03b1\u03b6\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c4\u03bf\u03c5 \u03b3\u03b5\u03bd\u03b9\u03ba\u03bf\u03cd \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03bf\u03cd. \u0388\u03c7\u03b5\u03b9 \u03b1\u03be\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03af\u03ba\u03b5\u03c5\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2.<\/p>\n<p>\u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03c9\u03c2:<\/p>\n<p>\u2022 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 <strong>\u03b9\u03c3\u03c7\u03c5\u03c1\u03cc \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc<\/strong> \u03c0\u03c1\u03cc\u03c9\u03c1\u03b7\u03c2 \u03c3\u03c4\u03b5\u03c6\u03b1\u03bd\u03b9\u03b1\u03af\u03b1\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ae \u03ac\u03bd\u03bf\u03b9\u03b1\u03c2<br \/>\n\u2022 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 <strong>\u03b1\u03bd\u03b5\u03be\u03ae\u03b3\u03b7\u03c4\u03b7\u03c2 \u03ae \u03b1\u03bd\u03b8\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b4\u03c5\u03c3\u03bb\u03b9\u03c0\u03b9\u03b4\u03b1\u03b9\u03bc\u03af\u03b1\u03c2<\/strong>, \u03c0\u03b1\u03c1\u03ac \u03c3\u03c9\u03c3\u03c4\u03ae \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae \u03ba\u03b1\u03b9 \u03b1\u03b3\u03c9\u03b3\u03ae<br \/>\n\u2022 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b5\u03af\u03c2 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<br \/>\n\u2022 \u03ae\u03c0\u03b9\u03b1 \u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03ad\u03ba\u03c0\u03c4\u03c9\u03c3\u03b7, \u03cc\u03c4\u03b1\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03bc\u03b5\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<br \/>\n\u2022 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03b3\u03b9\u03b1 <strong>\u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2<\/strong><\/p>\n<p>\u03a3\u03b5 \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03c3\u03b5\u03bd\u03ac\u03c1\u03b9\u03b1, \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 ApoE \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b8\u03ad\u03c3\u03b5\u03b9 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03c3\u03c4\u03bf \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03ba\u03b1\u03b8\u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c0\u03b9\u03bf \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2.<\/p>\n<p>\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03bf\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd \u03ae \u03bc\u03b9\u03ba\u03c4\u03ad\u03c2 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b5\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5, \u03b7 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03c6\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c0\u03b9\u03bf \u03b5\u03bd\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c4\u03c1\u03cc\u03c0\u03bf\u03c5 \u03b6\u03c9\u03ae\u03c2 \u03ae \u03c3\u03c4\u03b5\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7.<\/p>\n<p>\u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03c7\u03c9\u03c1\u03af\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ae \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2, \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7.<\/p>\n<p><!-- ==================== SECTION 8 ==================== --><\/p>\n<h2 id=\"sec8\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">8<\/span><\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03ce\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/span><\/h2>\n<p>\u0397 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bb\u03ae \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03c3\u03b5 \u03c3\u03c9\u03bb\u03b7\u03bd\u03ac\u03c1\u03b9\u03bf EDTA. \u0391\u03c0\u03cc \u03c4\u03bf \u03bf\u03bb\u03b9\u03ba\u03cc \u03b1\u03af\u03bc\u03b1 \u03b1\u03c0\u03bf\u03bc\u03bf\u03bd\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc \u03c5\u03bb\u03b9\u03ba\u03cc (DNA), \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03b1\u03bd\u03b1\u03bb\u03cd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ae Real-Time PCR \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03c0\u03bf\u03bb\u03c5\u03bc\u03bf\u03c1\u03c6\u03b9\u03c3\u03bc\u03ce\u03bd \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 APOE.<\/p>\n<p>\u0394\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1 \u03ae \u03ac\u03bb\u03bb\u03b7 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1. \u039f \u03b5\u03be\u03b5\u03c4\u03b1\u03b6\u03cc\u03bc\u03b5\u03bd\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03ae\u03c3\u03b5\u03b9 \u03ba\u03b1\u03bd\u03bf\u03bd\u03b9\u03ba\u03ac \u03c4\u03bf \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03cc \u03c4\u03bf\u03c5 \u03c0\u03c1\u03cc\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1.<\/p>\n<p>\u03a4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b1\u03c6\u03bf\u03c1\u03ac \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc \u03c5\u03bb\u03b9\u03ba\u03cc \u03c0\u03bf\u03c5 \u03b5\u03ba\u03c7\u03c5\u03bb\u03af\u03c3\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03cc \u03b5\u03c6\u2019 \u03cc\u03c1\u03bf\u03c5 \u03b6\u03c9\u03ae\u03c2, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03b4\u03b5\u03bd \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9.<\/p>\n<p>\u03a3\u03b5 \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03b2\u03b9\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03b7 ApoE \u03b4\u03b5\u03bd \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae, \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03ae \u03c0\u03b1\u03c1\u03bf\u03b4\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bc\u03af\u03b1 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03be\u03b9\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03b4\u03b9\u03b1\u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03c3\u03c4\u03bf \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b1\u03c4\u03cc\u03bc\u03bf\u03c5.<\/p>\n<p><!-- ==================== SECTION 9 ==================== --><\/p>\n<h2 id=\"sec9\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">9<\/span><\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0394\u03b5\u03af\u03b3\u03bc\u03b1 \u2013 \u039c\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 \u2013 \u0391\u03be\u03b9\u03bf\u03c0\u03b9\u03c3\u03c4\u03af\u03b1<\/span><\/h2>\n<p><strong>\u0394\u03b5\u03af\u03b3\u03bc\u03b1:<\/strong> \u039f\u03bb\u03b9\u03ba\u03cc \u03b1\u03af\u03bc\u03b1 \u03c3\u03b5 \u03c3\u03c9\u03bb\u03b7\u03bd\u03ac\u03c1\u03b9\u03bf EDTA<br \/>\n<strong>\u039c\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2:<\/strong> Real-Time PCR \u03bc\u03b5 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 FRET<br \/>\n<strong>\u0391\u03bd\u03c4\u03b9\u03b4\u03c1\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03b1:<\/strong> ApoE Real Time, \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b1 CE-IVD (Nuclear Laser Medicine srl)<br \/>\n<strong>\u0395\u03ba\u03c4\u03ad\u03bb\u03b5\u03c3\u03b7:<\/strong> \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u039c\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u0392\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 &amp; \u0393\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 Medisyn<\/p>\n<p>\u0397 Real-Time PCR \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03b5\u03b9 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ae \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03c0\u03bf\u03bb\u03c5\u03bc\u03bf\u03c1\u03c6\u03b9\u03c3\u03bc\u03ce\u03bd \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 APOE \u03c3\u03b5 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c7\u03c1\u03cc\u03bd\u03bf, \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c5\u03c8\u03b7\u03bb\u03ae \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c4\u03bf\u03bd \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03bf\u03c4\u03cd\u03c0\u03bf\u03c5.<\/p>\n<p>\u0397 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 FRET (Fluorescence Resonance Energy Transfer) \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03c5\u03c4\u03ad\u03c2 \u03c6\u03b8\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03bc\u03b5 \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 112 \u03ba\u03b1\u03b9 158. \u039c\u03b5 \u03b1\u03c5\u03c4\u03cc\u03bd \u03c4\u03bf\u03bd \u03c4\u03c1\u03cc\u03c0\u03bf \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03c8\u03b5\u03c5\u03b4\u03ce\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03be\u03b9\u03cc\u03c0\u03b9\u03c3\u03c4\u03b7 \u03c4\u03c5\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7.<\/p>\n<p>\u0395\u03c0\u03b5\u03b9\u03b4\u03ae \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7, \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae, \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03ae \u03bf\u03be\u03b5\u03af\u03b5\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2. \u039f \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03cc\u03c2 \u03c3\u03b5 \u03cc\u03bb\u03b7 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b6\u03c9\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b4\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03c0\u03b1\u03bd\u03ac\u03bb\u03b7\u03c8\u03b7.<\/p>\n<p>\u038c\u03bb\u03b1 \u03c4\u03b1 \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1 (\u03b1\u03c0\u03bf\u03bc\u03cc\u03bd\u03c9\u03c3\u03b7 DNA, \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7, \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7) \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b5\u03bb\u03b5\u03b3\u03c7\u03cc\u03bc\u03b5\u03bd\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd, \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c0\u03c1\u03cc\u03c4\u03c5\u03c0\u03b1 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2.<\/p>\n<p><!-- ==================== SECTION 10 ==================== --><\/p>\n<h2 id=\"sec10\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">10<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9\u03bc\u03ad\u03c2 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 &amp; \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1<\/span><\/h2>\n<p>\u03a3\u03c4\u03bf\u03bd \u03b3\u03b5\u03bd\u03b9\u03ba\u03cc \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03cc, \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac \u03b5\u03af\u03bd\u03b1\u03b9 <strong>ApoE E3\/E3<\/strong>, \u03bf \u03bf\u03c0\u03bf\u03af\u03bf\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af \u03c3\u03c4\u03bf\u03bd \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ac \u03bf\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03bf\u03c2.<\/p>\n<p>\u0386\u03bb\u03bb\u03bf\u03b9 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03bf\u03af, \u03cc\u03c0\u03c9\u03c2 <strong>E2\/E3<\/strong>, <strong>E3\/E4<\/strong> \u03ae <strong>E4\/E4<\/strong>, \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u00ab\u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2\u00bb, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ac \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03bc\u03b5 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03bf\u03bd \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03ac\u03bd\u03bf\u03b9\u03b1\u03c2.<\/p>\n<p>\u0397 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03bf\u03c5 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 (\u03c0.\u03c7. E3\/E4) \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03c9\u03c2 \u03b1\u03c1\u03b9\u03b8\u03bc\u03b7\u03c4\u03b9\u03ba\u03ae \u03c4\u03b9\u03bc\u03ae.<\/p>\n<p>\u0397 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf:<\/p>\n<p>\u2022 \u03c4\u03bf\u03c5 \u03bb\u03b9\u03c0\u03b9\u03b4\u03b1\u03b9\u03bc\u03b9\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03c6\u03af\u03bb (LDL, non-HDL, \u03c4\u03c1\u03b9\u03b3\u03bb\u03c5\u03ba\u03b5\u03c1\u03af\u03b4\u03b9\u03b1, \u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a))<br \/>\n\u2022 \u03c4\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03c6\u03cd\u03bb\u03bf\u03c5<br \/>\n\u2022 \u03c4\u03bf\u03c5 \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03bf\u03cd<br \/>\n\u2022 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1\u03c2 \u03ac\u03bb\u03bb\u03c9\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<br \/>\n\u2022 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2<\/p>\n<p>\u039c\u03b5 \u03b1\u03c0\u03bb\u03ac \u03bb\u03cc\u03b3\u03b9\u03b1, \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 ApoE \u03b4\u03b5\u03bd \u00ab\u03b4\u03af\u03bd\u03b5\u03b9 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u00bb, \u03b1\u03bb\u03bb\u03ac \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03b5\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7\u03c2 \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1:<\/strong><br \/>\n\u039f\u03b9 \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03b9 ApoE \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u00ab\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03af\u00bb \u03ae \u00ab\u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03af\u00bb. \u03a0\u03b5\u03c1\u03b9\u03b3\u03c1\u03ac\u03c6\u03bf\u03c5\u03bd \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c4\u03b1 \u03bb\u03b9\u03c0\u03af\u03b4\u03b9\u03b1, \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03c5\u03c0\u03cc\u03bb\u03bf\u03b9\u03c0\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5.<\/div>\n<p><!-- ==================== SECTION 11 ==================== --><\/p>\n<h2 id=\"sec11\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">11<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 ApoE3\/E3<\/span><\/h2>\n<p>\u039f \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 <strong>ApoE3\/E3<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf\u03c2 \u03c3\u03c4\u03bf\u03bd \u03b3\u03b5\u03bd\u03b9\u03ba\u03cc \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03cc \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ac \u03bf\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03bf\u03c2. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b4\u03b5\u03bd \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03bf\u03cd\u03c4\u03b5 \u03b3\u03b9\u03b1 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf \u03bf\u03cd\u03c4\u03b5 \u03b3\u03b9\u03b1 \u03bd\u03cc\u03c3\u03bf Alzheimer.<\/p>\n<p>\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u00ab\u03bf\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03bf\u03c2\u00bb \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf\u03c2. \u0386\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 ApoE3\/E3 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03bf\u03c5\u03bd \u03c5\u03c0\u03b5\u03c1\u03bb\u03b9\u03c0\u03b9\u03b4\u03b1\u03b9\u03bc\u03af\u03b1, \u03b1\u03b8\u03b7\u03c1\u03bf\u03c3\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7 \u03ae \u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03ad\u03ba\u03c0\u03c4\u03c9\u03c3\u03b7 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03ac\u03bb\u03bb\u03bf\u03b9 \u03b5\u03c0\u03b9\u03b2\u03b1\u03c1\u03c5\u03bd\u03c4\u03b9\u03ba\u03bf\u03af \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2, \u03cc\u03c0\u03c9\u03c2:<\/p>\n<p>\u2022 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 LDL-\u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7 \u03ae \u03c4\u03c1\u03b9\u03b3\u03bb\u03c5\u03ba\u03b5\u03c1\u03af\u03b4\u03b9\u03b1<br \/>\n\u2022 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7<br \/>\n\u2022 \u03c3\u03b1\u03ba\u03c7\u03b1\u03c1\u03ce\u03b4\u03b7\u03c2 \u03b4\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7\u03c2<br \/>\n\u2022 \u03ba\u03ac\u03c0\u03bd\u03b9\u03c3\u03bc\u03b1<br \/>\n\u2022 \u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c4\u03c1\u03cc\u03c0\u03bf\u03c2 \u03b6\u03c9\u03ae\u03c2<br \/>\n\u2022 \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7, \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 ApoE3\/E3 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03b1\u03c0\u03bf\u03c5\u03c3\u03af\u03b1 \u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c6\u03bf\u03c1\u03c4\u03af\u03bf\u03c5 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf, \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bc\u03c9\u03c2 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b9\u03c1\u03b5\u03af \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd, \u03c5\u03b9\u03bf\u03b8\u03ad\u03c4\u03b7\u03c3\u03b7 \u03c5\u03b3\u03b9\u03b5\u03b9\u03bd\u03bf\u03cd \u03c4\u03c1\u03cc\u03c0\u03bf\u03c5 \u03b6\u03c9\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ce\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5.<\/p>\n<p>\u039c\u03b5 \u03ac\u03bb\u03bb\u03b1 \u03bb\u03cc\u03b3\u03b9\u03b1, \u03c4\u03bf ApoE3\/E3 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u00ab\u03b5\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2\u00bb, \u03b1\u03bb\u03bb\u03ac \u03b1\u03c0\u03bb\u03ce\u03c2 \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03b2\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 ApoE \u03b4\u03b5\u03bd \u03b5\u03c0\u03b9\u03b2\u03b1\u03c1\u03cd\u03bd\u03b5\u03b9 \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03c4\u03bf \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5:<\/strong><br \/>\n\u0391\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03b5 ApoE3\/E3, \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd, \u03b7 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ae \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03c4\u03c9\u03bd \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ce\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03bf\u03af \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c0\u03c1\u03cc\u03b8\u03b5\u03c3\u03bc\u03b7 \u03c5\u03b3\u03b5\u03af\u03b1.<\/div>\n<p><!-- ==================== SECTION 12 ==================== --><\/p>\n<h2 id=\"sec12\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">12<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03af<\/span><\/h2>\n<p>\u03a0\u03b1\u03c1\u03cc\u03c4\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 ApoE \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1, \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b1\u03c4\u03b1\u03bd\u03bf\u03b7\u03c4\u03bf\u03af:<\/p>\n<p>\u2022 \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c0\u03b5\u03b9 \u03bc\u03b5 \u03b2\u03b5\u03b2\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03bd \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03bd\u03cc\u03c3\u03bf\u03c5 \u2014 \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf\u03bd \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03ba\u03b1\u03b8\u03bf\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03bf \u03c4\u03b5\u03bb\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<br \/>\n\u2022 \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03bc\u03b5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ac \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1, \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1<br \/>\n\u2022 \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b1\u03c6\u03bf\u03c1\u03ac \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf \u03c0\u03c1\u03bf\u03c3\u03ba\u03bf\u03bc\u03b9\u03c3\u03b8\u03ad\u03bd \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc \u03c5\u03bb\u03b9\u03ba\u03cc \u03c0\u03bf\u03c5 \u03b5\u03ba\u03c7\u03c5\u03bb\u03af\u03c3\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03cc<br \/>\n\u2022 \u03b4\u03b5\u03bd \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c5\u03c0\u03cc\u03c8\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b3\u03b5\u03bd\u03ad\u03c3\u03c4\u03b5\u03c1\u03bf\u03c5\u03c2 \u03ae \u03c0\u03b5\u03c1\u03b9\u03b2\u03b1\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 (\u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c4\u03c1\u03cc\u03c0\u03bf\u03c5 \u03b6\u03c9\u03ae\u03c2, \u03bd\u03ad\u03b5\u03c2 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2, \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2), \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03bf\u03b9 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf<\/p>\n<p>\u0393\u03b9\u03b1 \u03c4\u03bf\u03bd \u03bb\u03cc\u03b3\u03bf \u03b1\u03c5\u03c4\u03cc, \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 ApoE \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03b6\u03b7\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b9\u03b1\u03c4\u03c1\u03cc \u03c3\u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae\u03c2 \u03c0\u03c1\u03bf\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03b5\u03bd\u03b8\u03cd\u03bc\u03b9\u03c3\u03b7:<\/strong><br \/>\n\u0397 ApoE \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7\u03c2. \u0397 \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b4\u03b9\u03b1\u03bc\u03bf\u03c1\u03c6\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b9\u03bc\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7.<\/div>\n<p><!-- ==================== SECTION 13 ==================== --><\/p>\n<h2 id=\"sec13\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">13<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03c5\u03c7\u03bd\u03ac \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03bb\u03ac\u03b8\u03b7<\/span><\/h2>\n<p>\u03a4\u03bf \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf \u03bb\u03ac\u03b8\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c5 ApoE \u03b1\u03c0\u03bf\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b1, \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03c5\u03bd\u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd, \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2, \u03c4\u03c1\u03cc\u03c0\u03bf\u03c5 \u03b6\u03c9\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03bf\u03cd.<\/p>\n<p>\u0386\u03bb\u03bb\u03b1 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c3\u03c6\u03ac\u03bb\u03bc\u03b1\u03c4\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd:<\/p>\n<p>\u2022 \u03c5\u03c0\u03b5\u03c1\u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03c3\u03b5 \u03c6\u03bf\u03c1\u03b5\u03af\u03c2 ApoE4 \u03c7\u03c9\u03c1\u03af\u03c2 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2<br \/>\n\u2022 \u03c8\u03b5\u03c5\u03b4\u03ae \u03b1\u03af\u03c3\u03b8\u03b7\u03c3\u03b7 \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1\u03c2 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 ApoE3\/E3<br \/>\n\u2022 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c9\u03c2 \u00ab\u03c0\u03c1\u03cc\u03b2\u03bb\u03b5\u03c8\u03b7\u00bb Alzheimer<br \/>\n\u2022 \u03c0\u03b1\u03c1\u03ac\u03b2\u03bb\u03b5\u03c8\u03b7 \u03c4\u03c9\u03bd \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b9\u03bc\u03c9\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<br \/>\n\u2022 \u03b1\u03c0\u03bf\u03c5\u03c3\u03af\u03b1 \u03c3\u03c9\u03c3\u03c4\u03ae\u03c2 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03b8\u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/p>\n<p>\u0397 ApoE \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03bf\u03cd\u03c4\u03b5 \u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7. \u0391\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03bc\u03cc\u03bd\u03bf \u03ad\u03bd\u03b1 \u03ba\u03bf\u03bc\u03bc\u03ac\u03c4\u03b9 \u03c4\u03bf\u03c5 \u03c0\u03b1\u03b6\u03bb.<\/p>\n<p>\u0397 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03b5\u03b9 \u03cc\u03c4\u03b1\u03bd \u03b5\u03bd\u03c4\u03ac\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bf\u03c1\u03b3\u03b1\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf \u03c0\u03bb\u03ac\u03bd\u03bf \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03cc\u03c4\u03b1\u03bd \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a3\u03c5\u03c7\u03bd\u03cc \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03bb\u03ac\u03b8\u03bf\u03c2:<\/strong><br \/>\n\u0397 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03c7\u03ad\u03b4\u03b9\u03bf \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7\u03c2. \u0397 \u03b1\u03be\u03af\u03b1 \u03c4\u03b7\u03c2 ApoE \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2 \u2014 \u03cc\u03c7\u03b9 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03c3\u03c4\u03b7 \u03b3\u03bd\u03ce\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c5.<\/div>\n<p><!-- ==================== SECTION 14 ==================== --><\/p>\n<h2 id=\"sec14\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">14<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/span><\/h2>\n<p>\u0397 ApoE \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03b4\u03b5\u03af\u03ba\u03c4\u03b7 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7.<\/p>\n<p>\u039f \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03ba\u03b1\u03b8\u03bf\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf \u03b2\u03b1\u03b8\u03bc\u03cc \u03b1\u03c0\u03cc:<\/p>\n<p>\u2022 \u03c4\u03bf\u03bd \u03c4\u03c1\u03cc\u03c0\u03bf \u03b6\u03c9\u03ae\u03c2<br \/>\n\u2022 \u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2<br \/>\n\u2022 \u03c4\u03b7 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ae \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1<br \/>\n\u2022 \u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1<br \/>\n\u2022 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<\/p>\n<p>\u0391\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03b4\u03c5\u03c3\u03bc\u03b5\u03bd\u03b5\u03af\u03c2 \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c5\u03c2, \u03bf\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03bf\u03c5\u03bd \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03bd \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03ba\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf.<\/p>\n<p>\u039c\u03b5 \u03b1\u03c0\u03bb\u03ac \u03bb\u03cc\u03b3\u03b9\u03b1: \u03c4\u03b1 \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03b1 \u03b8\u03ad\u03c4\u03bf\u03c5\u03bd \u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf, \u03b1\u03bb\u03bb\u03ac \u03bf\u03b9 \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ad\u03c2 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ad\u03c2 \u03b4\u03b9\u03b1\u03bc\u03bf\u03c1\u03c6\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c0\u03bf\u03c1\u03b5\u03af\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a4\u03b5\u03bb\u03b9\u03ba\u03cc \u03bc\u03ae\u03bd\u03c5\u03bc\u03b1:<\/strong><br \/>\n\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 ApoE \u03ad\u03c7\u03b5\u03b9 \u03b1\u03be\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03c0\u03c1\u03ac\u03be\u03b7: \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae, \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03ac\u03c3\u03ba\u03b7\u03c3\u03b7, \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7.<\/div>\n<p><!-- ==================== FAQ ==================== --><\/p>\n<h2 id=\"faq\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">15<\/span><\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/span><\/h2>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0395\u03af\u03bd\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7;<\/summary>\n<p>\u038c\u03c7\u03b9. \u03a0\u03b1\u03c1\u03ad\u03c7\u03b5\u03b9 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0391\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03c7\u03c1\u03cc\u03bd\u03bf;<\/summary>\n<p>\u038c\u03c7\u03b9, \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 ApoE \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03af\u03b4\u03b9\u03bf\u03c2 \u03b5\u03c6\u2019 \u03cc\u03c1\u03bf\u03c5 \u03b6\u03c9\u03ae\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7;<\/summary>\n<p>\u038c\u03c7\u03b9, \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b1\u03c0\u03bb\u03ae \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03c3\u03b5 EDTA \u03c7\u03c9\u03c1\u03af\u03c2 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0391\u03bd \u03ad\u03c7\u03c9 ApoE4 \u03b8\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03c9 \u03c3\u03af\u03b3\u03bf\u03c5\u03c1\u03b1 Alzheimer;<\/summary>\n<p>\u038c\u03c7\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b1 \u2014 \u03bf \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03ad\u03ba\u03b2\u03b1\u03c3\u03b7 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03c4\u03c1\u03cc\u03c0\u03bf \u03b6\u03c9\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03af\u03bd\u03b7\u03c2;<\/summary>\n<p>\u039d\u03b1\u03b9, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03af\u03ba\u03b5\u03c5\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7;<\/summary>\n<p>\u038c\u03c7\u03b9, \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03c4\u03bf \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0388\u03c7\u03b5\u03b9 \u03bd\u03cc\u03b7\u03bc\u03b1 \u03b1\u03bd \u03ad\u03c7\u03c9 \u03ae\u03b4\u03b7 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03af\u03bd\u03b7;<\/summary>\n<p>\u03a3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03bd\u03b1\u03b9, \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ae \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03c0\u03b9\u03bf \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7\u03c2 \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c3\u03c5\u03b6\u03b7\u03c4\u03ae\u03c3\u03c9 \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03b5 \u03b9\u03b1\u03c4\u03c1\u03cc;<\/summary>\n<p>\u039d\u03b1\u03b9, \u03b7 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7\u03c2.<\/p>\n<\/details>\n<p><!-- ==================== SECTION 16 ==================== --><\/p>\n<h2 id=\"cta\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">16<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd<\/span><\/h2>\n<p><strong>\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03b9\u03b1\u03c4\u03c1\u03cc \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03cc \u03bc\u03b1\u03c2. \u039c\u03c0\u03bf\u03c1\u03b5\u03af\u03c4\u03b5 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03c3\u03b5\u03c4\u03b5 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ae \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.<\/strong><\/p>\n<div style=\"background: #fdf2f2; border: 2px solid #b70000; border-radius: 14px; padding: 18px; text-align: center;\">\n<div><strong>\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 ApoE \u03ae \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf:<\/strong><\/div>\n<div style=\"display: flex; gap: 10px; justify-content: center; flex-wrap: wrap; margin-top: 10px;\"><a style=\"background: #b70000; color: #fff; padding: 12px 18px; border-radius: 12px; text-decoration: none; font-weight: 600;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"nofollow noopener\">\ud83d\udcd8 \u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd<\/a><br \/>\n<a style=\"background: #b70000; color: #fff; padding: 12px 18px; border-radius: 12px; text-decoration: none; font-weight: 600;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/about-us\/appointments\/\" target=\"_blank\" rel=\"nofollow noopener\">\ud83d\udcc5 \u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd \u03a4\u03ce\u03c1\u03b1<\/a><\/div>\n<div style=\"margin-top: 10px; color: #374151;\">\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n<\/div>\n<p><!-- ==================== SECTION 17 ==================== --><\/p>\n<h2 id=\"bib\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">17<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/span><\/h2>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 8px; font-size: 14px;\"><strong>\u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u2013 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u039b\u03b1\u03bc\u03af\u03b1<\/strong><br \/>\nhttps:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 8px; font-size: 14px;\">Liu CC et al. <em>APOE and Alzheimer\u2019s disease<\/em>. Nat Rev Neurol.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\" rel=\"nofollow noopener\">https:\/\/www.ncbi.nlm.nih.gov\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 8px; font-size: 14px;\">Mahley RW. <em>Apolipoprotein E: cholesterol transport protein<\/em>. J Mol Med.<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 8px; font-size: 14px;\">Yamazaki Y et al. <em>ApoE and lipid metabolism in the brain<\/em>. Nat Rev Neurosci.<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 8px; font-size: 14px;\">Belloy ME et al. <em>ApoE genotypes and risk of Alzheimer disease<\/em>. JAMA Neurol.<br \/>\n<a href=\"https:\/\/jamanetwork.com\/\" rel=\"nofollow noopener\">https:\/\/jamanetwork.com\/<\/a><\/div>\n<div style=\"background: #f1f5f9; border-left: 4px solid #2563eb; padding: 10px 14px; border-radius: 8px; margin-top: 10px;\"><strong style=\"color: #1d4ed8;\">\u0395\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03bc\u03ad\u03bb\u03b5\u03b9\u03b1:<\/strong><br \/>\n\u0394\u03c1. \u03a0\u03b1\u03bd\u03c4\u03b5\u03bb\u03ae\u03c2 \u0391\u03bd\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03cc\u03c0\u03bf\u03c5\u03bb\u03bf\u03c2, \u0399\u03b1\u03c4\u03c1\u03cc\u03c2 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u2013 \u0392\u03b9\u03bf\u03c0\u03b1\u03b8\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2<br \/>\n\u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u039b\u03b1\u03bc\u03af\u03b1\u03c2, \u0388\u03c3\u03bb\u03b9\u03bd 19, \u039b\u03b1\u03bc\u03af\u03b1 35100<br \/>\n\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 ApoE (\u0391\u03c0\u03bf\u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u0395): \u0393\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03b3\u03b9\u03b1 \u039a\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u039a\u03af\u03bd\u03b4\u03c5\u03bd\u03bf &amp; \u039d\u03cc\u03c3\u03bf Alzheimer \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7: 27 \u0399\u03b1\u03bd\u03bf\u03c5\u03b1\u03c1\u03af\u03bf\u03c5 2026 \u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u03c3\u03cd\u03bd\u03bf\u03c8\u03b7: \u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 ApoE \u03b3\u03bf\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03b9 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c4\u03b7\u03c2 \u03b1\u03c0\u03bf\u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 \u0395 \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 Alzheimer. \u0393\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 Real-Time PCR \u03c3\u03b5 \u03bf\u03bb\u03b9\u03ba\u03cc \u03b1\u03af\u03bc\u03b1 (EDTA) \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7\u03c2, \u03cc\u03c7\u03b9 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \ud83d\udcd1 \u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1 \u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 ApoE [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":9442,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2534],"tags":[2890,2884,2888,2886,2889,2887,2885,144,78],"class_list":["post-9441","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exetaseis-aimatos","tag-alzheimer","tag-apoe","tag-apoe-alzheimer","tag-apolipoproteini-e","tag-genetiki-exetasi","tag-gonotypos-apoe","tag-exetasi-apoe","tag-kardiangeiakos-kindynos","tag-cholisterini"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/9441","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/comments?post=9441"}],"version-history":[{"count":6,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/9441\/revisions"}],"predecessor-version":[{"id":9448,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/9441\/revisions\/9448"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media\/9442"}],"wp:attachment":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media?parent=9441"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/categories?post=9441"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/tags?post=9441"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}