{"id":6699,"date":"2025-10-31T12:15:10","date_gmt":"2025-10-31T10:15:10","guid":{"rendered":"https:\/\/mikrobiologikolamia.gr\/staging\/?p=6699"},"modified":"2026-04-24T17:05:20","modified_gmt":"2026-04-24T14:05:20","slug":"antisomata-achr-musk-lrp4-myastheneia-gravis","status":"publish","type":"post","link":"https:\/\/mikrobiologikolamia.gr\/staging\/antisomata-achr-musk-lrp4-myastheneia-gravis\/","title":{"rendered":"\u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR, MuSK \u03ba\u03b1\u03b9 LRP4 \u2013 \u0394\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u039c\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 Gravis | \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u039b\u03b1\u03bc\u03af\u03b1"},"content":{"rendered":"<h1 id=\"top\" style=\"margin: 0 0 10px; font-weight: 900; color: #111827;\">\u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR, MuSK \u03ba\u03b1\u03b9 LRP4: \u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u039c\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 Gravis<\/h1>\n<div style=\"margin: 10px 0 12px; font-size: 13px; color: #6b7280;\">\u0394\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7: <time datetime=\"2025-10-31\">31 \u039f\u03ba\u03c4\u03c9\u03b2\u03c1\u03af\u03bf\u03c5 2025<\/time> \u2022 \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7: <time datetime=\"2026-04-24\">24 \u0391\u03c0\u03c1\u03b9\u03bb\u03af\u03bf\u03c5 2026<\/time><\/div>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0 18px;\">\n<p><strong>\u03a3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7 \u03c0\u03b5\u03c1\u03af\u03bb\u03b7\u03c8\u03b7:<\/strong><\/p>\n<p style=\"margin: 6px 0 0;\">\u03a4\u03b1 <strong>\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 <strong>\u039c\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 Gravis<\/strong>, \u03bc\u03b9\u03b1\u03c2 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03c3\u03cd\u03bd\u03b1\u03c8\u03b7\u03c2.<\/p>\n<p style=\"margin: 6px 0 0;\">\u038c\u03c4\u03b1\u03bd \u03c4\u03b1 AChR \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b1\u03bb\u03bb\u03ac \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd \u03cd\u03c0\u03bf\u03c0\u03c4\u03b1, \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b5\u03c0\u03b5\u03ba\u03c4\u03b5\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 <strong>\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 MuSK<\/strong>, <strong>\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 LRP4<\/strong> \u03ba\u03b1\u03b9 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf.<\/p>\n<p style=\"margin: 6px 0 0;\">\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b4\u03b5\u03bd \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03cc\u03bd\u03b7 \u03c4\u03b7\u03c2. \u03a4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b4\u03c5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7, \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc, \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1, \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bc\u03c5\u03bf\u03b3\u03c1\u03ac\u03c6\u03b7\u03bc\u03b1 \u03ba\u03b1\u03b9, \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9, \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03b8\u03ce\u03c1\u03b1\u03ba\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03b8\u03cd\u03bc\u03bf\u03c5 \u03b1\u03b4\u03ad\u03bd\u03b1.<\/p>\n<\/div>\n<nav id=\"toc\" style=\"background: #f9fafb; border: 1px solid #e5e7eb; border-radius: 14px; padding: 14px 16px; margin: 16px 0;\" aria-label=\"\u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1\"><strong>\u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1<\/strong><\/p>\n<ol style=\"margin: 10px 0 0 20px; line-height: 1.9;\">\n<li><a style=\"color: #dc2626;\" href=\"#section-1\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR;<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-2\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u039c\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 Gravis;<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-3\">\u03a0\u03cc\u03c4\u03b5 \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7;<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-4\">AChR, MuSK \u03ba\u03b1\u03b9 LRP4: \u03c0\u03bf\u03b9\u03b1 \u03b7 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac;<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-5\">\u03a4\u03cd\u03c0\u03bf\u03b9 AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-6\">\u03a3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-7\">\u03a0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-8\">\u039c\u03b5\u03b8\u03bf\u03b4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-9\">\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-10\">\u0391\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03b5 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-11\">\u0398\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1: \u03b5\u03c0\u03cc\u03bc\u03b5\u03bd\u03b1 \u03b2\u03ae\u03bc\u03b1\u03c4\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-12\">\u03a3\u03c5\u03bd\u03bf\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-13\">\u0397\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-14\">\u0398\u03cd\u03bc\u03c9\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b8\u03cd\u03bc\u03bf\u03c2 \u03b1\u03b4\u03ad\u03bd\u03b1\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-15\">\u03a0\u03b1\u03b9\u03b4\u03b9\u03ac, \u03ba\u03cd\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bd\u03b5\u03bf\u03b3\u03bd\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-16\">\u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-17\">\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-18\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03c0\u03b1\u03b3\u03af\u03b4\u03b5\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-19\">\u03a0\u03cc\u03c4\u03b5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7;<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-20\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b5\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-21\">\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#section-22\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 &amp; \u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/a><\/li>\n<\/ol>\n<\/nav>\n<hr style=\"border: 0; border-top: 2px solid #d1d5db; margin: 16px 0 24px;\" \/>\n<p><!-- ==================== SECTION 1 ==================== --><\/p>\n<section id=\"section-1\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">1<\/span><\/span>\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR;<\/h2>\n<p>\u03a4\u03b1 <strong>\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c4\u03c1\u03ad\u03c6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03bd\u03b1\u03bd\u03c4\u03af\u03bf\u03bd \u03c4\u03bf\u03c5 <strong>\u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03ba\u03b5\u03c4\u03c5\u03bb\u03bf\u03c7\u03bf\u03bb\u03af\u03bd\u03b7\u03c2<\/strong> \u03c3\u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae \u03c3\u03cd\u03bd\u03b1\u03c8\u03b7. \u0397 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae \u03c3\u03cd\u03bd\u03b1\u03c8\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03c3\u03b7\u03bc\u03b5\u03af\u03bf \u03cc\u03c0\u03bf\u03c5 \u03c4\u03bf \u03bd\u03b5\u03cd\u03c1\u03bf \u03bc\u03b5\u03c4\u03b1\u03b4\u03af\u03b4\u03b5\u03b9 \u03c4\u03bf \u03c3\u03ae\u03bc\u03b1 \u03c3\u03c4\u03bf\u03bd \u03bc\u03c5 \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9 \u03c3\u03cd\u03c3\u03c0\u03b1\u03c3\u03b7. \u0393\u03b9\u03b1 \u03bd\u03b1 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ac \u03b1\u03c5\u03c4\u03ae \u03b7 \u03bc\u03b5\u03c4\u03ac\u03b4\u03bf\u03c3\u03b7, \u03b7 \u03b1\u03ba\u03b5\u03c4\u03c5\u03bb\u03bf\u03c7\u03bf\u03bb\u03af\u03bd\u03b7 \u03b1\u03c0\u03b5\u03bb\u03b5\u03c5\u03b8\u03b5\u03c1\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03bd\u03b5\u03cd\u03c1\u03bf \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03b5\u03af\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03c6\u03ac\u03bd\u03b5\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03bc\u03c5\u03cc\u03c2.<\/p>\n<p>\u038c\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c4\u03bf\u03c5 AChR, \u03b7 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03c5\u03c4\u03ae \u03b5\u03c0\u03b9\u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03af\u03b1 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03ac\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9. \u03a4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03c0\u03bb\u03bf\u03ba\u03ac\u03c1\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1, \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03bf\u03cd\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae \u03ae \u03b5\u03c3\u03c9\u03c4\u03b5\u03c1\u03af\u03ba\u03b5\u03c5\u03c3\u03ae \u03c4\u03bf\u03c5 \u03ae \u03bd\u03b1 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd\u03c2 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c0\u03bf\u03c5 \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc \u03c4\u03c9\u03bd \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ce\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd. \u03a4\u03bf \u03c4\u03b5\u03bb\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03bf \u03bc\u03c5\u03c2 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ad\u03c3\u03c4\u03b5\u03c1\u03bf \u03c3\u03ae\u03bc\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03bd\u03b5\u03cd\u03c1\u03bf.<\/p>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 <strong>\u039c\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 Gravis<\/strong>. \u0397 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03c5\u03c0\u03ad\u03c1 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03c4\u03c5\u03c0\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03cc\u03c0\u03c9\u03c2 \u03b2\u03bb\u03b5\u03c6\u03b1\u03c1\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7, \u03b4\u03b9\u03c0\u03bb\u03c9\u03c0\u03af\u03b1, \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03ac\u03c0\u03bf\u03c3\u03b7, \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c6\u03c9\u03bd\u03ae\u03c2 \u03ae \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03c0\u03bf\u03c5 \u03c7\u03b5\u03b9\u03c1\u03bf\u03c4\u03b5\u03c1\u03b5\u03cd\u03b5\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1.<\/p>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03cc\u03bc\u03c9\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03ad\u03bd\u03b1 \u00ab\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03ae \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc\u00bb \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1. \u0397 \u03b1\u03be\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc, \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1, \u03c4\u03bf \u03b5\u03af\u03b4\u03bf\u03c2 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd, \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5, \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03ae \u03cc\u03c7\u03b9 \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ae\u03c2 \u03bc\u03bf\u03c1\u03c6\u03ae\u03c2, \u03c4\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03c5\u03c0\u03cc\u03bb\u03bf\u03b9\u03c0\u03bf \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc:<\/strong> \u03a4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf\u03c2 \u03bf\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03c3\u03c4\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 gravis, \u03b1\u03bb\u03bb\u03ac \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03b5\u03b9 \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf, \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03cc\u03c4\u03b1\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03c5\u03c0\u03b9\u03ba\u03ac.<\/div>\n<p>\u03a3\u03b5 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf, \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03c0\u03b1\u03bd\u03c4\u03ac \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1: \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03c3\u03ce\u03bc\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03b9 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03bd\u03b1\u03bd\u03c4\u03af\u03bf\u03bd \u03c4\u03b7\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03c3\u03cd\u03bd\u03b1\u03c8\u03b7\u03c2; \u0391\u03bd \u03b7 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1\u03b9, \u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac. \u0391\u03bd \u03b7 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c7\u03b9, \u03b7 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b5\u03c7\u03b9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1, \u03cc\u03c0\u03c9\u03c2 <strong>MuSK<\/strong> \u03ba\u03b1\u03b9 <strong>LRP4<\/strong>, \u03ae \u03bc\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 2 ==================== --><\/p>\n<section id=\"section-2\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">2<\/span><\/span>\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u039c\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 Gravis;<\/h2>\n<p>\u0397 <strong>\u039c\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 Gravis<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03c4\u03b7\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03c3\u03cd\u03bd\u03b1\u03c8\u03b7\u03c2. \u0397 \u03bb\u03ad\u03be\u03b7 \u00ab\u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u00bb \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03ac\u03c6\u03b5\u03b9 \u03c4\u03b7 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1, \u03b5\u03bd\u03ce \u03bf \u03cc\u03c1\u03bf\u03c2 \u00abgravis\u00bb \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03ac \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03cc\u03c4\u03b1\u03bd \u03c0\u03c1\u03bf\u03c3\u03b2\u03bb\u03b7\u03b8\u03bf\u03cd\u03bd \u03bf\u03b9 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03bf\u03af \u03ae \u03b2\u03bf\u03bb\u03b2\u03b9\u03ba\u03bf\u03af \u03bc\u03cd\u03b5\u03c2. \u03a3\u03ae\u03bc\u03b5\u03c1\u03b1, \u03bc\u03b5 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03b7 \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7.<\/p>\n<p>\u03a4\u03bf \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 <strong>\u03ba\u03c5\u03bc\u03b1\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03b7 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1<\/strong>. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ac. \u039f \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03bb\u03ac \u03c4\u03bf \u03c0\u03c1\u03c9\u03af \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf \u03b1\u03c0\u03cc\u03b3\u03b5\u03c5\u03bc\u03b1 \u03ae \u03c4\u03bf \u03b2\u03c1\u03ac\u03b4\u03c5. \u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03b9 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03bc\u03c5\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03b1\u03bd\u03ac\u03c0\u03b1\u03c5\u03c3\u03b7.<\/p>\n<p>\u0397 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03b2\u03bb\u03b5\u03c6\u03b1\u03c1\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03c0\u03bb\u03c9\u03c0\u03af\u03b1, \u03ae \u03bc\u03b5 \u03b3\u03b5\u03bd\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03bc\u03bf\u03c1\u03c6\u03ae \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03bc\u03cd\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03ce\u03c0\u03bf\u03c5, \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c4\u03ac\u03c0\u03bf\u03c3\u03b7\u03c2, \u03c4\u03b7\u03c2 \u03bf\u03bc\u03b9\u03bb\u03af\u03b1\u03c2, \u03c4\u03bf\u03c5 \u03b1\u03c5\u03c7\u03ad\u03bd\u03b1, \u03c4\u03c9\u03bd \u03ac\u03ba\u03c1\u03c9\u03bd \u03ae \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b1\u03c0\u03bd\u03bf\u03ae\u03c2. \u03a3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03ba\u03b1\u03b8\u03b1\u03c1\u03ac \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ae, \u03b5\u03bd\u03ce \u03c3\u03b5 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b3\u03b5\u03bd\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7.<\/p>\n<p>\u0397 \u039c\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 Gravis \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03c5\u03c0\u03b9\u03ba\u03ae \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1. \u039f \u03bc\u03c5\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03bf\u03bc\u03b9\u03ba\u03ac \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc\u03c2, \u03b1\u03bb\u03bb\u03ac \u03c4\u03bf \u03c3\u03ae\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03bd\u03b5\u03cd\u03c1\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b5\u03c0\u03b1\u03c1\u03ba\u03ad\u03c2. \u0391\u03c5\u03c4\u03cc\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03bb\u03cc\u03b3\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03b7 CK \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2, \u03b5\u03bd\u03ce \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03bc\u03bf\u03c1\u03c6\u03ae, \u03c4\u03b1 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 <strong>AChR<\/strong>. \u03a3\u03b5 \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd <strong>MuSK<\/strong> \u03ae <strong>LRP4<\/strong> \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1. \u03a3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b4\u03b5\u03bd \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b5\u03c2 \u03bc\u03b5\u03b8\u03cc\u03b4\u03bf\u03c5\u03c2, \u03c0\u03b1\u03c1\u03cc\u03c4\u03b9 \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ae \u03bc\u03b5 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u039c\u03b5 \u03b1\u03c0\u03bb\u03ac \u03bb\u03cc\u03b3\u03b9\u03b1:<\/strong> \u0397 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03bf \u03bc\u03c5\u03c2 \u00ab\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03ad\u03c6\u03b5\u03c4\u03b1\u03b9\u00bb \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b1. \u03a3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03b5\u03c0\u03b9\u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03af\u03b1 \u03bd\u03b5\u03cd\u03c1\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03bc\u03c5\u03cc\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c3\u03c4\u03b1\u03b8\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03bf\u03c5\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 3 ==================== --><\/p>\n<section id=\"section-3\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">3<\/span><\/span>\u03a0\u03cc\u03c4\u03b5 \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7;<\/h2>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 gravis \u03ae \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03b8\u03b5\u03af \u03b1\u03bd\u03b5\u03be\u03ae\u03b3\u03b7\u03c4\u03b7 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae\u03c2. \u0394\u03b5\u03bd \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03b3\u03b5\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c0\u03c1\u03bf\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2. \u0397 \u03b1\u03be\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1.<\/p>\n<p>\u039f \u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c4\u03b7 \u03b6\u03b7\u03c4\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03b2\u03bb\u03b5\u03c6\u03b1\u03c1\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1, \u03b4\u03b9\u03c0\u03bb\u03c9\u03c0\u03af\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b5\u03be\u03b7\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ac\u03bb\u03bb\u03b7 \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03ae \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03b9\u03c4\u03af\u03b1, \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03c3\u03c4\u03b7 \u03bc\u03ac\u03c3\u03b7\u03c3\u03b7, \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03ac\u03c0\u03bf\u03c3\u03b7, \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03b9\u03bb\u03af\u03b1 \u03ae \u03b3\u03b5\u03bd\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1.<\/p>\n<ul>\n<li><strong>\u039f\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1:<\/strong> \u03c0\u03c4\u03ce\u03c3\u03b7 \u03b2\u03bb\u03b5\u03c6\u03ac\u03c1\u03bf\u03c5, \u03b4\u03b9\u03c0\u03bb\u03c9\u03c0\u03af\u03b1, \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03bc\u03b1\u03c4\u03b9\u03ce\u03bd, \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03bf \u03c4\u03ad\u03bb\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b1\u03c2.<\/li>\n<li><strong>\u0392\u03bf\u03bb\u03b2\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1:<\/strong> \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03ac\u03c0\u03bf\u03c3\u03b7, \u03c0\u03bd\u03b9\u03b3\u03bc\u03bf\u03bd\u03ae, \u03c1\u03b9\u03bd\u03b9\u03ba\u03ae \u03c6\u03c9\u03bd\u03ae, \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03b9\u03bb\u03af\u03b1, \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03c4\u03b7 \u03bc\u03ac\u03c3\u03b7\u03c3\u03b7.<\/li>\n<li><strong>\u039c\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03ac\u03ba\u03c1\u03c9\u03bd:<\/strong> \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03b5 \u03c3\u03ba\u03ac\u03bb\u03b5\u03c2, \u03c3\u03ae\u03ba\u03c9\u03bc\u03b1 \u03c7\u03b5\u03c1\u03b9\u03ce\u03bd, \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7 \u03bf\u03c1\u03b8\u03bf\u03c3\u03c4\u03b1\u03c3\u03af\u03b1 \u03ae \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ad\u03c2 \u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03ba\u03bf\u03c5\u03c1\u03ac\u03b6\u03bf\u03c5\u03bd \u03b4\u03c5\u03c3\u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1.<\/li>\n<li><strong>\u0391\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1:<\/strong> \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1, \u03bf\u03c1\u03b8\u03cc\u03c0\u03bd\u03bf\u03b9\u03b1, \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03cd \u03b2\u03ae\u03c7\u03b1 \u03ae \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03bd\u03bf\u03ae.<\/li>\n<\/ul>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b6\u03b7\u03c4\u03b7\u03b8\u03b5\u03af \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ae\u03b4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03b1\u03bb\u03bb\u03ac \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bf\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c4\u03b1\u03be\u03b9\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7. \u0397 \u03b4\u03b9\u03ac\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd AChR-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2, MuSK-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2, LRP4-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ae \u03bf\u03c1\u03bf\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae, \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03b3\u03b9\u03b1 \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf.<\/p>\n<p>\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b7 \u03c0\u03c1\u03cc\u03c3\u03b8\u03b9\u03b1 \u03bc\u03b5\u03c3\u03bf\u03b8\u03c9\u03c1\u03b1\u03ba\u03b9\u03ba\u03ae \u03bc\u03ac\u03b6\u03b1 \u03ae \u03b8\u03cd\u03bc\u03c9\u03bc\u03b1, \u03c4\u03b1 AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b6\u03b7\u03c4\u03b7\u03b8\u03bf\u03cd\u03bd, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 \u03b8\u03cd\u03bc\u03bf\u03c5. \u0391\u03bd\u03c4\u03af\u03c3\u03c4\u03c1\u03bf\u03c6\u03b1, \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 AChR-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1, \u03c3\u03c5\u03c7\u03bd\u03ac \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03b8\u03ce\u03c1\u03b1\u03ba\u03bf\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 4 ==================== --><\/p>\n<section id=\"section-4\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">4<\/span><\/span>AChR, MuSK \u03ba\u03b1\u03b9 LRP4: \u03c0\u03bf\u03b9\u03b1 \u03b7 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac;<\/h2>\n<p>\u03a4\u03b1 AChR, MuSK \u03ba\u03b1\u03b9 LRP4 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 \u03c4\u03c1\u03b5\u03b9\u03c2 \u03b2\u03b1\u03c3\u03b9\u03ba\u03bf\u03af \u03bf\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03af \u03c3\u03c4\u03cc\u03c7\u03bf\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03cd\u03b3\u03c7\u03c1\u03bf\u03bd\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2. \u038c\u03bb\u03bf\u03b9 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae \u03c3\u03cd\u03bd\u03b1\u03c8\u03b7, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03af\u03b4\u03b9\u03b1 \u03c0\u03b1\u03b8\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03bf\u03cd\u03c4\u03b5 \u03c4\u03b7\u03bd \u03af\u03b4\u03b9\u03b1 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1.<\/p>\n<p>\u03a4\u03b1 <strong>AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong> \u03c3\u03c4\u03c1\u03ad\u03c6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03bd\u03b1\u03bd\u03c4\u03af\u03bf\u03bd \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03ba\u03b5\u03c4\u03c5\u03bb\u03bf\u03c7\u03bf\u03bb\u03af\u03bd\u03b7\u03c2. \u0395\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bc\u03b5 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ae \u03b3\u03b5\u03bd\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1. \u03a4\u03b1 <strong>MuSK \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong> \u03c3\u03c4\u03c1\u03ad\u03c6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03bd\u03b1\u03bd\u03c4\u03af\u03bf\u03bd \u03bc\u03b9\u03b1\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03c3\u03cd\u03bd\u03b1\u03c8\u03b7\u03c2. \u0397 MuSK-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03b2\u03bf\u03bb\u03b2\u03b9\u03ba\u03ac, \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03ac \u03ae \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1. \u03a4\u03b1 <strong>LRP4 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong> \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd \u03ad\u03bd\u03b1\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 MuSK \u03ba\u03b1\u03b9 \u03b6\u03b7\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b4\u03b9\u03c0\u03bb\u03ac \u03bf\u03c1\u03bf\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\">\u2194\ufe0f \u03a3\u03cd\u03c1\u03b5\u03c4\u03b5 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03c4\u03ae\u03bb\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03af\u03bd\u03b1\u03ba\u03b1<\/div>\n<div style=\"overflow-x: auto; margin: 10px 0 14px;\">\n<table style=\"width: 100%; border-collapse: collapse; min-width: 760px;\">\n<thead>\n<tr style=\"background: #f9fafb;\">\n<th style=\"text-align: left; padding: 10px; border-bottom: 1px solid #e5e7eb;\">\u0391\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1<\/th>\n<th style=\"text-align: left; padding: 10px; border-bottom: 1px solid #e5e7eb;\">\u03a3\u03c4\u03cc\u03c7\u03bf\u03c2<\/th>\n<th style=\"text-align: left; padding: 10px; border-bottom: 1px solid #e5e7eb;\">\u03a0\u03cc\u03c4\u03b5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf<\/th>\n<th style=\"text-align: left; padding: 10px; border-bottom: 1px solid #e5e7eb;\">\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\"><strong>AChR<\/strong><\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u03a5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1\u03c2 \u03b1\u03ba\u03b5\u03c4\u03c5\u03bb\u03bf\u03c7\u03bf\u03bb\u03af\u03bd\u03b7\u03c2<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u03a0\u03c1\u03ce\u03c4\u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03c3\u03b5 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u03a3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2, \u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\"><strong>MuSK<\/strong><\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">Muscle-specific kinase<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u038c\u03c4\u03b1\u03bd AChR \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03ae \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b7 \u03b2\u03bf\u03bb\u03b2\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c0\u03b9\u03bf \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\"><strong>LRP4<\/strong><\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">LRP4, \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 agrin-LRP4-MuSK<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u03a3\u03b5 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 AChR\/MuSK \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u03a7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf \u03c3\u03b5 \u03b4\u03cd\u03c3\u03ba\u03bf\u03bb\u03b5\u03c2 \u03ae \u03bf\u03c1\u03bf\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03b3\u03bd\u03ce\u03c3\u03b5\u03b9\u03c2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7, \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c3\u03c5\u03c7\u03bd\u03ac \u03be\u03b5\u03ba\u03b9\u03bd\u03ac \u03bc\u03b5 AChR. \u0391\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9, \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af MuSK. \u0391\u03bd \u03ba\u03b1\u03b9 \u03b1\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03be\u03b5\u03c4\u03b1\u03c3\u03c4\u03b5\u03af LRP4 \u03ae \u03c0\u03b9\u03bf \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf \u03c0\u03ac\u03bd\u03b5\u03bb \u03c3\u03b5 \u03ba\u03ad\u03bd\u03c4\u03c1\u03bf \u03bd\u03b5\u03c5\u03c1\u03bf\u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2. \u0397 \u03c3\u03b5\u03b9\u03c1\u03ac \u03b1\u03c5\u03c4\u03ae \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc\u03bb\u03c5\u03c4\u03b7\u00b7 \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b8\u03b5\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 5 ==================== --><\/p>\n<section id=\"section-5\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">5<\/span><\/span>\u03a4\u03cd\u03c0\u03bf\u03b9 AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/h2>\n<p>\u03a4\u03b1 AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c7\u03c9\u03c1\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03c3\u03b5 \u03b5\u03c0\u03b9\u03bc\u03ad\u03c1\u03bf\u03c5\u03c2 \u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03af\u03b5\u03c2 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03c4\u03c1\u03cc\u03c0\u03bf \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5\u03c2. \u0397 \u03b4\u03b9\u03ac\u03ba\u03c1\u03b9\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ae \u03ad\u03c7\u03b5\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b2\u03bf\u03b7\u03b8\u03ac \u03bd\u03b1 \u03ba\u03b1\u03c4\u03b1\u03bd\u03bf\u03b7\u03b8\u03b5\u03af \u03b3\u03b9\u03b1\u03c4\u03af \u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03ad\u03bd\u03c4\u03b1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03bf\u03c1\u03c6\u03ae \u03b1\u03c0\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae.<\/p>\n<p><strong>Binding \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1:<\/strong> \u0395\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c4\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03b6\u03b7\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9. \u03a3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03ba\u03b5\u03c4\u03c5\u03bb\u03bf\u03c7\u03bf\u03bb\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03c4\u03bf\u03bd \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03bf\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03b4\u03b5\u03af\u03ba\u03c4\u03b7 \u03c4\u03b7\u03c2 AChR-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2. \u03a3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ac \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03b1, \u03cc\u03c4\u03b1\u03bd \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03c4\u03b1\u03b9 \u00abAChR antibodies\u00bb, \u03b5\u03bd\u03bd\u03bf\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c4\u03b1 binding \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1.<\/p>\n<p><strong>Blocking \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1:<\/strong> \u03a0\u03b1\u03c1\u03b5\u03bc\u03c0\u03bf\u03b4\u03af\u03b6\u03bf\u03c5\u03bd \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ac \u03c4\u03b7 \u03c3\u03cd\u03bd\u03b4\u03b5\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03ba\u03b5\u03c4\u03c5\u03bb\u03bf\u03c7\u03bf\u03bb\u03af\u03bd\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1. \u0394\u03b5\u03bd \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c7\u03c9\u03c1\u03b9\u03c3\u03c4\u03ac \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03c0\u03c1\u03ac\u03be\u03b7, \u03b1\u03bb\u03bb\u03ac \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1 \u03c3\u03b5 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2.<\/p>\n<p><strong>Modulating \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1:<\/strong> \u03a0\u03c1\u03bf\u03ba\u03b1\u03bb\u03bf\u03cd\u03bd \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b1\u03c1\u03b9\u03b8\u03bc\u03bf\u03cd \u03c4\u03c9\u03bd \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ce\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u03c3\u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03c6\u03ac\u03bd\u03b5\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03bc\u03c5\u03cc\u03c2, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03bf\u03b4\u03b7\u03b3\u03bf\u03cd\u03bd \u03c3\u03b5 \u03b5\u03c3\u03c9\u03c4\u03b5\u03c1\u03af\u03ba\u03b5\u03c5\u03c3\u03b7 \u03ae \u03b1\u03c0\u03bf\u03b4\u03cc\u03bc\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1. \u0397 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bd\u03b9\u03c3\u03c7\u03cd\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1.<\/p>\n<p>\u0394\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bd\u03b1 \u03ba\u03ac\u03bd\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03c4\u03c1\u03b5\u03b9\u03c2 \u03c5\u03c0\u03bf\u03c4\u03cd\u03c0\u03bf\u03c5\u03c2. \u039f \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u03b5\u03c0\u03b9\u03bb\u03ad\u03b3\u03b5\u03b9 \u03c0\u03bf\u03b9\u03bf\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf\u03c2 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03cc. \u03a3\u03b5 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2, \u03c4\u03bf AChR binding \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03ba\u03b5\u03c4\u03cc \u03c9\u03c2 \u03b1\u03c1\u03c7\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2. \u03a3\u03b5 \u03b4\u03cd\u03c3\u03ba\u03bf\u03bb\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2, \u03cc\u03bc\u03c9\u03c2, \u03bf \u03c0\u03b9\u03bf \u03b5\u03ba\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b5\u03af\u03c9\u03c3\u03b7:<\/strong> \u03a4\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03bf \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c5\u03c0\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2, \u03b1\u03bb\u03bb\u03ac \u03b1\u03bd \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b1\u03b9\u03c1\u03b9\u03ac\u03b6\u03b5\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bc\u03b5 MuSK, LRP4 \u03ae \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 6 ==================== --><\/p>\n<section id=\"section-6\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">6<\/span><\/span>\u03a3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf<\/h2>\n<p>\u0397 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03cd\u03c3\u03ba\u03bf\u03bb\u03b7 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b1\u03bb\u03bb\u03ac\u03b6\u03bf\u03c5\u03bd. \u039f \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03be\u03b5\u03c4\u03b1\u03c3\u03c4\u03b5\u03af \u03c3\u03b5 \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae \u03c0\u03bf\u03c5 \u03b1\u03b9\u03c3\u03b8\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b1, \u03b5\u03bd\u03ce \u03bb\u03af\u03b3\u03b5\u03c2 \u03ce\u03c1\u03b5\u03c2 \u03b1\u03c1\u03b3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03b9 \u03b5\u03bc\u03c6\u03b1\u03bd\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1. \u0391\u03c5\u03c4\u03ae \u03b7 \u03b4\u03b9\u03b1\u03ba\u03cd\u03bc\u03b1\u03bd\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03c0\u03bf\u03c5 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc.<\/p>\n<p>\u03a4\u03b1 <strong>\u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ae \u03b1\u03c1\u03c7\u03b9\u03ba\u03ae \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b7. \u0397 \u03b2\u03bb\u03b5\u03c6\u03b1\u03c1\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03bf\u03bd\u03cc\u03c0\u03bb\u03b5\u03c5\u03c1\u03b7 \u03ae \u03b1\u03bc\u03c6\u03bf\u03c4\u03b5\u03c1\u03cc\u03c0\u03bb\u03b5\u03c5\u03c1\u03b7, \u03bd\u03b1 \u03c7\u03b5\u03b9\u03c1\u03bf\u03c4\u03b5\u03c1\u03b5\u03cd\u03b5\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03c9\u03bd \u03bc\u03b1\u03c4\u03b9\u03ce\u03bd \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03bd\u03ac\u03c0\u03b1\u03c5\u03c3\u03b7. \u0397 \u03b4\u03b9\u03c0\u03bb\u03c9\u03c0\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03b1\u03c4\u03b5\u03c5\u03b8\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2 \u03b2\u03bb\u03ad\u03bc\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ae \u03c3\u03c4\u03bf \u03c4\u03ad\u03bb\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b1\u03c2.<\/p>\n<p>\u03a4\u03b1 <strong>\u03b2\u03bf\u03bb\u03b2\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac. \u03a0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03ac\u03c0\u03bf\u03c3\u03b7, \u03c0\u03bd\u03b9\u03b3\u03bc\u03bf\u03bd\u03ae, \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7 \u03c3\u03c4\u03b7 \u03bc\u03ac\u03c3\u03b7\u03c3\u03b7, \u03c1\u03b9\u03bd\u03b9\u03ba\u03ae \u03c6\u03c9\u03bd\u03ae, \u03b2\u03c1\u03b1\u03c7\u03bd\u03ac\u03b4\u03b1 \u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03ba\u03b1\u03b8\u03b1\u03c1\u03ae\u03c2 \u03ac\u03c1\u03b8\u03c1\u03c9\u03c3\u03b7\u03c2. \u0391\u03c5\u03c4\u03ac \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c5\u03be\u03ac\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03b9\u03c3\u03c1\u03cc\u03c6\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae.<\/p>\n<p>\u0397 <strong>\u03b3\u03b5\u03bd\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1<\/strong> \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03bf\u03bd \u03b1\u03c5\u03c7\u03ad\u03bd\u03b1, \u03c4\u03bf\u03c5\u03c2 \u03ce\u03bc\u03bf\u03c5\u03c2, \u03c4\u03bf\u03c5\u03c2 \u03bc\u03b7\u03c1\u03bf\u03cd\u03c2 \u03ae \u03c4\u03b1 \u03ac\u03ba\u03c1\u03b1. \u039f \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03ad\u03b2\u03b5\u03b9 \u03c3\u03ba\u03ac\u03bb\u03b5\u03c2, \u03bd\u03b1 \u03c3\u03b7\u03ba\u03c9\u03b8\u03b5\u03af \u03b1\u03c0\u03cc \u03ba\u03b1\u03c1\u03ad\u03ba\u03bb\u03b1, \u03bd\u03b1 \u03c3\u03b7\u03ba\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b1 \u03c7\u03ad\u03c1\u03b9\u03b1 \u03c0\u03ac\u03bd\u03c9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03ba\u03b5\u03c6\u03ac\u03bb\u03b9 \u03ae \u03bd\u03b1 \u03ba\u03c1\u03b1\u03c4\u03ae\u03c3\u03b5\u03b9 \u03b1\u03bd\u03c4\u03b9\u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03b1 \u03b3\u03b9\u03b1 \u03ce\u03c1\u03b1. \u0397 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b4\u03b5\u03bd \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c0\u03cc\u03bd\u03bf \u03ae \u03b1\u03b9\u03c3\u03b8\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2.<\/p>\n<p>\u03a4\u03b1 <strong>\u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c0\u03b9\u03bf \u03b5\u03c0\u03b5\u03af\u03b3\u03bf\u03c5\u03c3\u03b1 \u03c0\u03bb\u03b5\u03c5\u03c1\u03ac \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5. \u0394\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1, \u03bf\u03c1\u03b8\u03cc\u03c0\u03bd\u03bf\u03b9\u03b1, \u03b1\u03b4\u03cd\u03bd\u03b1\u03bc\u03bf\u03c2 \u03b2\u03ae\u03c7\u03b1\u03c2 \u03ae \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03cc\u03c4\u03b9 \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03b4\u03b5\u03bd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03ac\u03c1\u03b5\u03b9 \u03b2\u03b1\u03b8\u03b9\u03ac \u03b1\u03bd\u03ac\u03c3\u03b1 \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 7 ==================== --><\/p>\n<section id=\"section-7\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">7<\/span><\/span>\u03a0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1<\/h2>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c0\u03bb\u03ae \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1. \u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03bf\u03c1\u03cc\u03c2 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2. \u0394\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03ad\u03bb\u03b8\u03b5\u03b9 \u03bf\u03c0\u03bf\u03b9\u03b1\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03ce\u03c1\u03b1, \u03b5\u03ba\u03c4\u03cc\u03c2 \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ac\u03bb\u03bb\u03b7 \u03bf\u03b4\u03b7\u03b3\u03af\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03b1 \u03b9\u03b1\u03c4\u03c1\u03cc \u03ae \u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf.<\/p>\n<p>\u0397 \u03bb\u03ae\u03c8\u03b7 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03ba\u03cc\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c5\u03b8\u03b1\u03af\u03c1\u03b5\u03c4\u03b1. \u0391\u03bd \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c0\u03c5\u03c1\u03b9\u03b4\u03bf\u03c3\u03c4\u03b9\u03b3\u03bc\u03af\u03bd\u03b7, \u03ba\u03bf\u03c1\u03c4\u03b9\u03ba\u03bf\u03c3\u03c4\u03b5\u03c1\u03bf\u03b5\u03b9\u03b4\u03ae, \u03b1\u03bd\u03bf\u03c3\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ac, IVIG, \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ae \u03ad\u03c7\u03b5\u03b9 \u03c5\u03c0\u03bf\u03b2\u03bb\u03b7\u03b8\u03b5\u03af \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b1 \u03c3\u03b5 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c6\u03b1\u03af\u03c1\u03b5\u03c3\u03b7, \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03bd\u03b7\u03bc\u03b5\u03c1\u03ce\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03b9\u03b1\u03c4\u03c1\u03cc \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf. \u0391\u03c5\u03c4\u03ad\u03c2 \u03bf\u03b9 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03b2\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03c3\u03c4\u03b7\u03bd \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1, \u03b1\u03ba\u03cc\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03bd \u03b4\u03b5\u03bd \u03b1\u03bb\u03bb\u03ac\u03b6\u03bf\u03c5\u03bd \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03bd \u03af\u03b4\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2.<\/p>\n<ul>\n<li><strong>\u039d\u03b7\u03c3\u03c4\u03b5\u03af\u03b1:<\/strong> \u0394\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9.<\/li>\n<li><strong>\u0394\u03b5\u03af\u03b3\u03bc\u03b1:<\/strong> \u039f\u03c1\u03cc\u03c2 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2.<\/li>\n<li><strong>\u038f\u03c1\u03b1 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2:<\/strong> \u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc.<\/li>\n<li><strong>\u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1:<\/strong> \u0394\u03b5\u03bd \u03b4\u03b9\u03b1\u03ba\u03cc\u03c0\u03c4\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03bf\u03b4\u03b7\u03b3\u03af\u03b1.<\/li>\n<li><strong>\u03a7\u03c1\u03cc\u03bd\u03bf\u03c2 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7\u03c2:<\/strong> \u0395\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf \u03ba\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b1\u03bd \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf\u03c0\u03b9\u03ba\u03ac \u03ae \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b5\u03c1\u03b3\u03b1\u03b6\u03cc\u03bc\u03b5\u03bd\u03bf \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf.<\/li>\n<\/ul>\n<div style=\"background: #fff7ed; border-left: 4px solid #ea580c; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc:<\/strong> \u0391\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c0\u03c1\u03bf\u03b7\u03b3\u03b7\u03b8\u03b5\u03af IVIG \u03ae \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c6\u03b1\u03af\u03c1\u03b5\u03c3\u03b7, \u03b7 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03b1 \u03b9\u03b1\u03c4\u03c1\u03cc, \u03b3\u03b9\u03b1\u03c4\u03af \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 \u03c0\u03b1\u03c1\u03bf\u03b4\u03b9\u03ba\u03ac \u03c4\u03bf\u03c5\u03c2 \u03c4\u03af\u03c4\u03bb\u03bf\u03c5\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 8 ==================== --><\/p>\n<section id=\"section-8\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">8<\/span><\/span>\u039c\u03b5\u03b8\u03bf\u03b4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7\u03c2<\/h2>\n<p>\u03a4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR, MuSK \u03ba\u03b1\u03b9 LRP4 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03c5\u03b8\u03bf\u03cd\u03bd \u03bc\u03b5 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ad\u03c2. \u0397 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1, \u03c4\u03b7\u03bd \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u03c4\u03b9\u03c2 \u03bc\u03bf\u03bd\u03ac\u03b4\u03b5\u03c2 \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03cc\u03c1\u03b9\u03bf \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2.<\/p>\n<p>\u0397 <strong>RIA<\/strong> \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ae \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ae \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03c5\u03c0\u03bf\u03b4\u03bf\u03bc\u03ad\u03c2 \u03bb\u03cc\u03b3\u03c9 \u03c1\u03b1\u03b4\u03b9\u03bf\u03ca\u03c3\u03bf\u03c4\u03cc\u03c0\u03c9\u03bd. \u0397 <strong>ELISA<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b4\u03b9\u03b1\u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b7 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ac \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03bf\u03c3\u03bf\u03b5\u03bd\u03b6\u03c5\u03bc\u03b9\u03ba\u03ae \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7. \u0397 <strong>CLIA<\/strong> \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03b5\u03b9 \u03b1\u03c5\u03c4\u03bf\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03b5 \u03ba\u03b1\u03bb\u03ae \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1.<\/p>\n<p>\u03a4\u03b1 <strong>cell-based assays<\/strong> \u03ad\u03c7\u03bf\u03c5\u03bd \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1 \u03c3\u03b5 \u03b4\u03cd\u03c3\u03ba\u03bf\u03bb\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2. \u03a3\u03b5 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03bc\u03b5\u03b8\u03cc\u03b4\u03bf\u03c5\u03c2, \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03b1 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03c6\u03ac\u03bd\u03b5\u03b9\u03b1 \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03bc\u03b5 \u03c0\u03b9\u03bf \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03bc\u03cc\u03c1\u03c6\u03c9\u03c3\u03b7, \u03ba\u03ac\u03c4\u03b9 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c8\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03c6\u03b1\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ad\u03c2. \u0394\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b1 \u03b7 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03cc\u03bb\u03bf\u03c5\u03c2, \u03b1\u03bb\u03bb\u03ac \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b1 \u03c3\u03b5 \u03bf\u03c1\u03bf\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1.<\/p>\n<p>\u0388\u03bd\u03b1 \u03c3\u03c5\u03c7\u03bd\u03cc \u03bb\u03ac\u03b8\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b1\u03c0\u03b5\u03c5\u03b8\u03b5\u03af\u03b1\u03c2 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03b1\u03c1\u03b9\u03b8\u03bc\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03b1. \u0391\u03bd \u03ad\u03bd\u03b1 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 IU\/L \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03bf nmol\/L, \u03ae \u03b1\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03bb\u03b1\u03c4\u03c6\u03cc\u03c1\u03bc\u03b5\u03c2, \u03b7 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03c0\u03bb\u03b1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae. \u039f \u03c3\u03c9\u03c3\u03c4\u03cc\u03c2 \u03c4\u03c1\u03cc\u03c0\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b1 \u03cc\u03c1\u03b9\u03b1 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7\u03c2 \u03bc\u03b5\u03b8\u03cc\u03b4\u03bf\u03c5.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u039a\u03bb\u03b5\u03b9\u03b4\u03af \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1\u03c2:<\/strong> \u03a0\u03ac\u03bd\u03c4\u03b1 \u03ba\u03bf\u03b9\u03c4\u03ac\u03bc\u03b5 \u03c4\u03bf cut-off \u03c4\u03bf\u03c5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03bf\u03c5, \u03c4\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1. \u039f \u03b1\u03c0\u03cc\u03bb\u03c5\u03c4\u03bf\u03c2 \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2 \u03bc\u03cc\u03bd\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03b5\u03af.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 9 ==================== --><\/p>\n<section id=\"section-9\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">9<\/span><\/span>\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd<\/h2>\n<p>\u0397 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c4\u03c9\u03bd AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03bf \u03cc\u03c1\u03b9\u03bf \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 \u03c4\u03bf\u03c5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03bf\u03c5. \u03a4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac, \u03bf\u03c1\u03b9\u03b1\u03ba\u03ac \u03ae \u03b8\u03b5\u03c4\u03b9\u03ba\u03ac, \u03ae \u03bd\u03b1 \u03b4\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c1\u03b9\u03b8\u03bc\u03b7\u03c4\u03b9\u03ba\u03ae \u03c4\u03b9\u03bc\u03ae. \u0397 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b5\u03bd\u03b9\u03c3\u03c7\u03cd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ac.<\/p>\n<p>\u0388\u03bd\u03b1 <strong>\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/strong> \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b4\u03b5\u03bd \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf. \u0394\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b4\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1. \u0391\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c3\u03b5 \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1, \u03c3\u03b5 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03bd\u03cc\u03c3\u03bf \u03ae \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bb\u03ac\u03b2\u03b5\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1.<\/p>\n<p>\u0388\u03bd\u03b1 <strong>\u03bf\u03c1\u03b9\u03b1\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/strong> \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae. \u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u03bc\u03b7 \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1 \u03ae \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03cc\/\u03bc\u03b5\u03b8\u03bf\u03b4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03b6\u03ae\u03c4\u03b7\u03bc\u03b1. \u03a3\u03b5 \u03c4\u03ad\u03c4\u03bf\u03b9\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03b7 \u03b5\u03c0\u03b1\u03bd\u03ac\u03bb\u03b7\u03c8\u03b7, \u03b7 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03af\u03c9\u03c3\u03b7 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf \u03ae \u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c3\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03ba\u03ad\u03bd\u03c4\u03c1\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b7.<\/p>\n<p>\u0388\u03bd\u03b1 <strong>\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03c5\u03c0\u03ad\u03c1 AChR-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \u039f \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u03b8\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03ae\u03c3\u03b5\u03b9 \u03b1\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03b7 \u03ba\u03b1\u03c4\u03b1\u03bd\u03bf\u03bc\u03ae \u03c4\u03b7\u03c2 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c4\u03b1\u03b9\u03c1\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u03bc\u03b5 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03ae \u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\">\u2194\ufe0f \u03a3\u03cd\u03c1\u03b5\u03c4\u03b5 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03c4\u03ae\u03bb\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03af\u03bd\u03b1\u03ba\u03b1<\/div>\n<div style=\"overflow-x: auto; margin: 10px 0 14px;\">\n<table style=\"width: 100%; border-collapse: collapse; min-width: 760px;\">\n<thead>\n<tr style=\"background: #f9fafb;\">\n<th style=\"text-align: left; padding: 10px; border-bottom: 1px solid #e5e7eb;\">\u0391\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/th>\n<th style=\"text-align: left; padding: 10px; border-bottom: 1px solid #e5e7eb;\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9<\/th>\n<th style=\"text-align: left; padding: 10px; border-bottom: 1px solid #e5e7eb;\">\u03a4\u03b9 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u0391\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u0394\u03b5\u03bd \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf.<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u0391\u03bd \u03b7 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9, \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 MuSK, LRP4 \u03ba\u03b1\u03b9 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u039f\u03c1\u03b9\u03b1\u03ba\u03cc<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u0391\u03bc\u03c6\u03af\u03b2\u03bf\u03bb\u03b7 \u03ae \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1.<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u0395\u03c0\u03b1\u03bd\u03ac\u03bb\u03b7\u03c8\u03b7, \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03af\u03c9\u03c3\u03b7 \u03ae cell-based assay \u03c3\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u0398\u03b5\u03c4\u03b9\u03ba\u03cc<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u03a3\u03c5\u03bc\u03b2\u03b1\u03c4\u03cc \u03bc\u03b5 AChR-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c4\u03b1\u03b9\u03c1\u03b9\u03ac\u03b6\u03b5\u03b9 \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1.<\/td>\n<td style=\"padding: 10px; border-bottom: 1px solid #f3f4f6;\">\u039d\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7, \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b8\u03cd\u03bc\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc\u03c2.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p><strong>\u039f \u03c4\u03af\u03c4\u03bb\u03bf\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1\u03c2.<\/strong> \u0388\u03bd\u03b1\u03c2 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c2 \u03c4\u03af\u03c4\u03bb\u03bf\u03c2 \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03c5\u03c0\u03bf\u03c7\u03c1\u03b5\u03c9\u03c4\u03b9\u03ba\u03ac \u03c0\u03b9\u03bf \u03b2\u03b1\u03c1\u03b9\u03ac \u03bd\u03cc\u03c3\u03bf, \u03ba\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf\u03c2 \u03c4\u03af\u03c4\u03bb\u03bf\u03c2 \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b1 \u03ae\u03c0\u03b9\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1. \u0397 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 10 ==================== --><\/p>\n<section id=\"section-10\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">10<\/span><\/span>\u0391\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03b5 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1<\/h2>\n<p>\u03a4\u03bf \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc AChR \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ae \u03c0\u03b7\u03b3\u03ae \u03c3\u03cd\u03b3\u03c7\u03c5\u03c3\u03b7\u03c2. \u03a0\u03bf\u03bb\u03bb\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd \u03cc\u03c4\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03c3\u03c4\u03b7\u03ba\u03b5 \u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1. \u0391\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03cc. \u0397 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 AChR-\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae, \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03cc\u03c4\u03b1\u03bd \u03b1\u03c6\u03bf\u03c1\u03ac \u03bc\u03cc\u03bd\u03bf \u03c4\u03b1 \u03bc\u03ac\u03c4\u03b9\u03b1 \u03ae \u03cc\u03c4\u03b1\u03bd \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03c4\u03af\u03c4\u03bb\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03c1\u03c7\u03b9\u03ba\u03ae \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf.<\/p>\n<p>\u03a3\u03b5 \u03c4\u03ad\u03c4\u03bf\u03b9\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03c5\u03bd\u03b5\u03c7\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 <strong>MuSK \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong>. \u0391\u03bd \u03ba\u03b1\u03b9 \u03b1\u03c5\u03c4\u03ac \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03be\u03b5\u03c4\u03b1\u03c3\u03c4\u03bf\u03cd\u03bd <strong>LRP4 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong>, \u03b9\u03b4\u03af\u03c9\u03c2 \u03cc\u03c4\u03b1\u03bd \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03c0\u03b5\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae. \u03a0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1, \u03c4\u03bf single-fiber EMG \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03ce\u03c3\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae \u03bc\u03b5\u03c4\u03ac\u03b4\u03bf\u03c3\u03b7.<\/p>\n<p>\u03a5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b7 \u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03af\u03b1 \u03c4\u03b7\u03c2 <strong>\u03bf\u03c1\u03bf\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2<\/strong>, \u03cc\u03c0\u03bf\u03c5 \u03bf\u03b9 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b5\u03c2 \u03bf\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ae. \u03a3\u03b5 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7, \u03b3\u03b9\u03b1\u03c4\u03af \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03bc\u03b9\u03bc\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c4\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc:<\/strong> \u0397 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03b4\u03b5\u03bd \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03bc\u03af\u03b1 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2. \u0397 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bc\u03c5\u03bf\u03b3\u03c1\u03ac\u03c6\u03b7\u03bc\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 11 ==================== --><\/p>\n<section id=\"section-11\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">11<\/span><\/span>\u0398\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1: \u03b5\u03c0\u03cc\u03bc\u03b5\u03bd\u03b1 \u03b2\u03ae\u03bc\u03b1\u03c4\u03b1<\/h2>\n<p>\u0388\u03bd\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc AChR \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1. \u03a4\u03bf \u03b5\u03c0\u03cc\u03bc\u03b5\u03bd\u03bf \u03b2\u03ae\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03bd\u03b1 \u00ab\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b5\u03af \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1\u00bb, \u03b1\u03bb\u03bb\u03ac \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03c9\u03b8\u03b5\u03af \u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03ba\u03c4\u03b9\u03bc\u03b7\u03b8\u03b5\u03af \u03b7 \u03ad\u03ba\u03c4\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5. \u039f \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u03b8\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03ae\u03c3\u03b5\u03b9 \u03b1\u03bd \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ae \u03ae \u03b3\u03b5\u03bd\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7, \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b2\u03bf\u03bb\u03b2\u03b9\u03ba\u03ac \u03ae \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7.<\/p>\n<p>\u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03b8\u03ce\u03c1\u03b1\u03ba\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c4\u03bf\u03c5 \u03b8\u03cd\u03bc\u03bf\u03c5 \u03b1\u03b4\u03ad\u03bd\u03b1. \u0397 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03b8\u03cd\u03bc\u03c9\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03c7\u03b5\u03af\u03c1\u03b9\u03c3\u03b7. \u0391\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b8\u03cd\u03bc\u03c9\u03bc\u03b1, \u03b7 \u03c3\u03c7\u03ad\u03c3\u03b7 AChR-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03b8\u03cd\u03bc\u03bf \u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03bf\u03bd \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc.<\/p>\n<p>\u0397 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03c3\u03ad\u03b3\u03b3\u03b9\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae, \u03b1\u03bd\u03bf\u03c3\u03bf\u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03ba\u03bf\u03c1\u03c4\u03b9\u03ba\u03bf\u03c3\u03c4\u03b5\u03c1\u03bf\u03b5\u03b9\u03b4\u03ae, \u03b1\u03bd\u03bf\u03c3\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ac, \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ae \u03b5\u03c0\u03b5\u03af\u03b3\u03bf\u03c5\u03c3\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 IVIG \u03ba\u03b1\u03b9 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c6\u03b1\u03af\u03c1\u03b5\u03c3\u03b7 \u03c3\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2. \u0397 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ae \u03b4\u03b5\u03bd \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03cc\u03bd\u03bf, \u03b1\u03bb\u03bb\u03ac \u03b1\u03c0\u03cc \u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2.<\/p>\n<ul>\n<li>\u039d\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03ae \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1\u03c2.<\/li>\n<li>\u0388\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b8\u03cd\u03bc\u03bf\u03c5 \u03bc\u03b5 \u03b1\u03be\u03bf\u03bd\u03b9\u03ba\u03ae \u03ae \u03bc\u03b1\u03b3\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b8\u03ce\u03c1\u03b1\u03ba\u03bf\u03c2.<\/li>\n<li>\u0397\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03af\u03c9\u03c3\u03b7.<\/li>\n<li>\u0388\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03c9\u03bd \u03c3\u03c5\u03bd\u03bf\u03b4\u03ce\u03bd \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03c9\u03bd \u03bd\u03bf\u03c3\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd.<\/li>\n<li>\u0395\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc\u03c2.<\/li>\n<\/ul>\n<\/section>\n<p><!-- ==================== SECTION 12 ==================== --><\/p>\n<section id=\"section-12\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">12<\/span><\/span>\u03a3\u03c5\u03bd\u03bf\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2<\/h2>\n<p>\u0397 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b5\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc, \u03c0\u03ad\u03c1\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR, MuSK \u03ba\u03b1\u03b9 LRP4, \u03c3\u03c5\u03c7\u03bd\u03ac \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03c5\u03c1\u03cd\u03c4\u03b5\u03c1\u03bf\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2. \u039f \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b9\u03c0\u03bb\u03cc\u03c2: \u03bd\u03b1 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03b9\u03c7\u03b8\u03b5\u03af \u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03ba\u03c4\u03b9\u03bc\u03b7\u03b8\u03b5\u03af \u03b7 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c0\u03bf\u03c6\u03ac\u03c3\u03b5\u03b9\u03c2.<\/p>\n<ul>\n<li><strong>TSH, FT4, \u03b1\u03bd\u03c4\u03b9-TPO, \u03b1\u03bd\u03c4\u03b9-TG:<\/strong> \u0397 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b5 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03cc\u03c0\u03c9\u03c2 \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7, \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03c0\u03b1\u03bb\u03bc\u03ce\u03bd \u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1.<\/li>\n<li><strong>\u0393\u03b5\u03bd\u03b9\u03ba\u03ae \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2:<\/strong> \u03a7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03b3\u03b9\u03b1 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c0\u03c1\u03b9\u03bd \u03ae \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03b1\u03bd\u03bf\u03c3\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ce\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03b9\u03ce\u03bd.<\/li>\n<li><strong>\u0397\u03c0\u03b1\u03c4\u03b9\u03ba\u03ac \u03ad\u03bd\u03b6\u03c5\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1:<\/strong> \u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd.<\/li>\n<li><strong>CRP \u03ba\u03b1\u03b9 \u03a4\u039a\u0395:<\/strong> \u039c\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03bf\u03c5\u03bd \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03bf\u03c5\u03c2 \u03ae \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/li>\n<li><strong>ANA \u03ba\u03b1\u03b9 ENA:<\/strong> \u0396\u03b7\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b5\u03c0\u03b9\u03bb\u03b5\u03ba\u03c4\u03b9\u03ba\u03ac \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03ac\u03bb\u03bb\u03bf \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1.<\/li>\n<li><strong>\u0392\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7 \u039212, \u03c6\u03c5\u03bb\u03bb\u03b9\u03ba\u03cc, \u03c6\u03b5\u03c1\u03c1\u03b9\u03c4\u03af\u03bd\u03b7:<\/strong> \u0394\u03b5\u03bd \u03b4\u03b9\u03b1\u03b3\u03b9\u03b3\u03bd\u03ce\u03c3\u03ba\u03bf\u03c5\u03bd \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1, \u03b1\u03bb\u03bb\u03ac \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03bf\u03c5\u03bd \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7\u03c2 \u03ae \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.<\/li>\n<\/ul>\n<p>\u039f \u03c3\u03c5\u03bd\u03bf\u03b4\u03cc\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03c5\u03c0\u03b5\u03c1\u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \u03a0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03ba\u03b1\u03b8\u03bf\u03b4\u03b7\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c0\u03bb\u03ac\u03bd\u03bf. \u03a3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c0\u03bf\u03c5 \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03bb\u03ac\u03b2\u03b5\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ac, \u03bf \u03c0\u03c1\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b1\u03c0\u03cc \u03ad\u03bd\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c0\u03bf\u03c5 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03c1\u03c7\u03b9\u03ba\u03ae \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03ae\u03c0\u03b9\u03b1\u03c2 \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ae\u03c2 \u03bc\u03bf\u03c1\u03c6\u03ae\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 13 ==================== --><\/p>\n<section id=\"section-13\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">13<\/span><\/span>\u0397\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2<\/h2>\n<p>\u039f \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf\u03c2 \u03cc\u03c4\u03b1\u03bd \u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03be\u03b5\u03ba\u03ac\u03b8\u03b1\u03c1\u03b7. \u0395\u03bb\u03ad\u03b3\u03c7\u03b5\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ac \u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae \u03bc\u03b5\u03c4\u03ac\u03b4\u03bf\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03ce\u03c3\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b1\u03c8\u03b7 \u03bd\u03b5\u03cd\u03c1\u03bf\u03c5-\u03bc\u03c5\u03cc\u03c2.<\/p>\n<p>\u03a4\u03bf <strong>repetitive nerve stimulation<\/strong> \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03b1 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03b9\u03ba\u03ac \u03b5\u03c1\u03b5\u03b8\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03ac\u03c6\u03b5\u03b9 \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b1\u03b4\u03b9\u03b1\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7\u03c2. \u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b3\u03b5\u03bd\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1, \u03b1\u03bb\u03bb\u03ac \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b5\u03c5\u03b1\u03af\u03c3\u03b8\u03b7\u03c4\u03b7 \u03c3\u03b5 \u03ba\u03b1\u03b8\u03b1\u03c1\u03ac \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ae \u03bc\u03bf\u03c1\u03c6\u03ae.<\/p>\n<p>\u03a4\u03bf <strong>single-fiber EMG<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b5\u03c5\u03b1\u03af\u03c3\u03b8\u03b7\u03c4\u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03bc\u03b5\u03c4\u03ac\u03b4\u03bf\u03c3\u03b7\u03c2. \u039c\u03b5\u03c4\u03c1\u03ac \u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bb\u03b7\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c4\u03b7 \u03bc\u03b5\u03c4\u03ac\u03b4\u03bf\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03bd\u03b5\u03cd\u03c1\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03af\u03bd\u03b1\u03c2. \u0395\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf \u03cc\u03c4\u03b1\u03bd \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b1\u03bb\u03bb\u03ac \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd \u03c4\u03c5\u03c0\u03b9\u03ba\u03ac.<\/p>\n<p>\u039f \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b1\u03c6\u03bf\u03c1\u03ac \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c4\u03bf\u03bd \u03b8\u03cd\u03bc\u03bf \u03b1\u03b4\u03ad\u03bd\u03b1. \u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 AChR-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1, \u03b7 \u03b1\u03be\u03bf\u03bd\u03b9\u03ba\u03ae \u03ae \u03bc\u03b1\u03b3\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b8\u03ce\u03c1\u03b1\u03ba\u03bf\u03c2 \u03b2\u03bf\u03b7\u03b8\u03ac \u03c3\u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03b3\u03b9\u03b1 \u03b8\u03cd\u03bc\u03c9\u03bc\u03b1 \u03ae \u03c5\u03c0\u03b5\u03c1\u03c0\u03bb\u03b1\u03c3\u03af\u03b1 \u03b8\u03cd\u03bc\u03bf\u03c5. \u0397 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ae \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1, \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc, \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b8\u03b5\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1.<\/p>\n<p>\u03a3\u03b5 \u03ac\u03c4\u03c5\u03c0\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03b1\u03b9\u03c3\u03b8\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2, \u03ad\u03bd\u03c4\u03bf\u03bd\u03bf\u03c2 \u03c0\u03cc\u03bd\u03bf\u03c2, \u03bc\u03bf\u03bd\u03cc\u03c0\u03bb\u03b5\u03c5\u03c1\u03b7 \u03c0\u03c5\u03c1\u03b1\u03bc\u03b9\u03b4\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b5\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ae \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd \u03bd\u03b5\u03c5\u03c1\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7, \u03cc\u03c0\u03c9\u03c2 MRI \u03b5\u03b3\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5 \u03ae \u03b1\u03c5\u03c7\u03b5\u03bd\u03b9\u03ba\u03ae\u03c2 \u03bc\u03bf\u03af\u03c1\u03b1\u03c2, \u03b3\u03b9\u03b1 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03bc\u03cc \u03ac\u03bb\u03bb\u03c9\u03bd \u03b1\u03b9\u03c4\u03b9\u03ce\u03bd.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 14 ==================== --><\/p>\n<section id=\"section-14\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">14<\/span><\/span>\u0398\u03cd\u03bc\u03c9\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b8\u03cd\u03bc\u03bf\u03c2 \u03b1\u03b4\u03ad\u03bd\u03b1\u03c2<\/h2>\n<p>\u039f \u03b8\u03cd\u03bc\u03bf\u03c2 \u03b1\u03b4\u03ad\u03bd\u03b1\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03ae \u03b8\u03ad\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd AChR-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1. \u0395\u03af\u03bd\u03b1\u03b9 \u03cc\u03c1\u03b3\u03b1\u03bd\u03bf \u03c4\u03bf\u03c5 \u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c9\u03c1\u03af\u03bc\u03b1\u03bd\u03c3\u03b7 \u03c4\u03c9\u03bd \u03a4-\u03bb\u03b5\u03bc\u03c6\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd. \u03a3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03bf\u03bd \u03b8\u03cd\u03bc\u03bf, \u03cc\u03c0\u03c9\u03c2 \u03c5\u03c0\u03b5\u03c1\u03c0\u03bb\u03b1\u03c3\u03af\u03b1 \u03ae \u03b8\u03cd\u03bc\u03c9\u03bc\u03b1.<\/p>\n<p>\u03a4\u03bf <strong>\u03b8\u03cd\u03bc\u03c9\u03bc\u03b1<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03b3\u03ba\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b8\u03cd\u03bc\u03bf\u03c5 \u03b1\u03b4\u03ad\u03bd\u03b1. \u0394\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03b5 AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b8\u03cd\u03bc\u03c9\u03bc\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03ce\u03c3\u03c4\u03b5 \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b5\u03c3\u03bf\u03b8\u03c9\u03c1\u03b1\u03ba\u03af\u03bf\u03c5 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c3\u03c5\u03c7\u03bd\u03cc \u03b2\u03ae\u03bc\u03b1 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \u0397 \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03b2\u03bf\u03b7\u03b8\u03ac \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03c9\u03b8\u03b5\u03af \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03ac\u03b6\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b8\u03c9\u03c1\u03b1\u03ba\u03bf\u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7.<\/p>\n<p>\u0397 <strong>\u03b8\u03c5\u03bc\u03b5\u03ba\u03c4\u03bf\u03bc\u03ae<\/strong> \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03b6\u03b7\u03c4\u03b7\u03b8\u03b5\u03af \u03c3\u03b5 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03b3\u03b5\u03bd\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 AChR-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03ae \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b8\u03cd\u03bc\u03c9\u03bc\u03b1. \u0394\u03b5\u03bd \u03b1\u03c6\u03bf\u03c1\u03ac \u03cc\u03bb\u03bf\u03c5\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03c0\u03cc\u03c6\u03b1\u03c3\u03b7 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03bf\u03bc\u03ac\u03b4\u03b1, \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1, \u03c4\u03b7 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1, \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1:<\/strong> \u0398\u03b5\u03c4\u03b9\u03ba\u03ac AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03b1\u03c5\u03c4\u03cc\u03bc\u03b1\u03c4\u03b1 \u03b8\u03cd\u03bc\u03c9\u03bc\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03bb\u03cc\u03b3\u03bf \u03bd\u03b1 \u03c3\u03c5\u03b6\u03b7\u03c4\u03b7\u03b8\u03b5\u03af \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03b8\u03ce\u03c1\u03b1\u03ba\u03bf\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03b1 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03cc\u03b3\u03bf.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 15 ==================== --><\/p>\n<section id=\"section-15\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">15<\/span><\/span>\u03a0\u03b1\u03b9\u03b4\u03b9\u03ac, \u03ba\u03cd\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bd\u03b5\u03bf\u03b3\u03bd\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1<\/h2>\n<p>\u0397 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c3\u03c4\u03b1 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03ad\u03b3\u03b3\u03b9\u03c3\u03b7, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03b8\u03b5\u03af \u03b7 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03bd\u03b5\u03b1\u03bd\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c3\u03c5\u03b3\u03b3\u03b5\u03bd\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03b5\u03bd\u03b9\u03ba\u03ac \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03b1. \u03a4\u03b1 \u03c3\u03c5\u03b3\u03b3\u03b5\u03bd\u03ae \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03b1 \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03bf\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03b7 \u03c0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b7.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03ba\u03cd\u03b7\u03c3\u03b7, \u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03b5\u03af\u03bd\u03b5\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae, \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03c9\u03b8\u03b5\u03af \u03ae \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03c9\u03b8\u03b5\u03af. \u0397 \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03af\u03b4\u03b9\u03b1 \u03c3\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2. \u03a4\u03b1 AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c0\u03b5\u03c1\u03ac\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03c0\u03bb\u03b1\u03ba\u03bf\u03cd\u03bd\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03bf\u03c5\u03bd <strong>\u03c0\u03b1\u03c1\u03bf\u03b4\u03b9\u03ba\u03ae \u03bd\u03b5\u03bf\u03b3\u03bd\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1<\/strong>. \u03a4\u03bf \u03bd\u03b5\u03bf\u03b3\u03bd\u03cc \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03b5\u03b9 \u03c5\u03c0\u03bf\u03c4\u03bf\u03bd\u03af\u03b1, \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03c4\u03b7 \u03c3\u03af\u03c4\u03b9\u03c3\u03b7, \u03b1\u03b4\u03cd\u03bd\u03b1\u03bc\u03bf \u03ba\u03bb\u03ac\u03bc\u03b1 \u03ae \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1.<\/p>\n<p>\u0397 \u03bd\u03b5\u03bf\u03b3\u03bd\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c0\u03b1\u03c1\u03bf\u03b4\u03b9\u03ba\u03ae, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03c4\u03b1 \u03bc\u03b7\u03c4\u03c1\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c0\u03bf\u03bc\u03b1\u03ba\u03c1\u03cd\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1\u03b4\u03b9\u03b1\u03ba\u03ac \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03c4\u03bf\u03c5 \u03bd\u03b5\u03bf\u03b3\u03bd\u03bf\u03cd. \u03a0\u03b1\u03c1\u2019 \u03cc\u03bb\u03b1 \u03b1\u03c5\u03c4\u03ac, \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b1\u03c0\u03cc \u03bd\u03b5\u03bf\u03b3\u03bd\u03bf\u03bb\u03cc\u03b3\u03bf. \u0397 \u03c0\u03c1\u03bf\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bc\u03b1\u03b9\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03b5\u03bf\u03b3\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b1\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03ba\u03cd\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03c4\u03bf\u03ba\u03b5\u03c4\u03cc \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03c3\u03c4\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1, \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c7\u03b5\u03af\u03c1\u03b9\u03c3\u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae\u03c2 \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7\u03c2. \u0397 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b1 \u03bc\u03b5 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03cc\u03b3\u03bf \u03ba\u03b1\u03b9 \u03bc\u03b1\u03b9\u03b5\u03c5\u03c4\u03ae\u03c1\u03b1 \u03bc\u03b5 \u03b5\u03bc\u03c0\u03b5\u03b9\u03c1\u03af\u03b1 \u03c3\u03b5 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03ba\u03cd\u03b7\u03c3\u03b7\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 16 ==================== --><\/p>\n<section id=\"section-16\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">16<\/span><\/span>\u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1<\/h2>\n<p>\u039f\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae \u03bc\u03b5\u03c4\u03ac\u03b4\u03bf\u03c3\u03b7. \u0391\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ba\u03ac\u03b8\u03b5 \u03c4\u03ad\u03c4\u03bf\u03b9\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03b1\u03c0\u03b1\u03b3\u03bf\u03c1\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae. \u03a3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03bc\u03c9\u03c2 \u03cc\u03c4\u03b9 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae, \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b9\u03b1\u03c4\u03c1\u03bf\u03cd \u03ba\u03b1\u03b9 \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5-\u03bf\u03c6\u03ad\u03bb\u03bf\u03c5\u03c2.<\/p>\n<ul>\n<li><strong>\u0391\u03bc\u03b9\u03bd\u03bf\u03b3\u03bb\u03c5\u03ba\u03bf\u03c3\u03af\u03b4\u03b5\u03c2:<\/strong> \u039c\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae \u03bc\u03b5\u03c4\u03ac\u03b4\u03bf\u03c3\u03b7.<\/li>\n<li><strong>\u03a6\u03b8\u03bf\u03c1\u03b9\u03bf\u03ba\u03b9\u03bd\u03bf\u03bb\u03cc\u03bd\u03b5\u03c2:<\/strong> \u0388\u03c7\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1.<\/li>\n<li><strong>\u039c\u03b1\u03ba\u03c1\u03bf\u03bb\u03af\u03b4\u03b5\u03c2:<\/strong> \u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03c3\u03bf\u03c5\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c3\u03b5 \u03b5\u03c5\u03b1\u03af\u03c3\u03b8\u03b7\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2.<\/li>\n<li><strong>\u039c\u03b1\u03b3\u03bd\u03ae\u03c3\u03b9\u03bf:<\/strong> \u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03c3\u03b5 \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03ad\u03b2\u03b9\u03b1 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03ae \u03c5\u03c8\u03b7\u03bb\u03ad\u03c2 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2.<\/li>\n<li><strong>\u0392-\u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2:<\/strong> \u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7 \u03ae \u03c4\u03b7\u03bd \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1.<\/li>\n<li><strong>\u039d\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03bf\u03af \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03ad\u03c2:<\/strong> \u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03c3\u03b5 \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b5\u03af\u03bf \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1.<\/li>\n<\/ul>\n<p>\u039f \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03b5 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03bd\u03b7\u03bc\u03b5\u03c1\u03ce\u03bd\u03b5\u03b9 \u03ba\u03ac\u03b8\u03b5 \u03b9\u03b1\u03c4\u03c1\u03cc, \u03bf\u03b4\u03bf\u03bd\u03c4\u03af\u03b1\u03c4\u03c1\u03bf \u03ae \u03b1\u03bd\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \u0391\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b5\u03c0\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7, \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03b1\u03bd\u03c4\u03b9\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03ae \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03ad\u03b2\u03b9\u03b1 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae.<\/p>\n<div style=\"background: #fff7ed; border-left: 4px solid #ea580c; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac:<\/strong> \u039c\u03b7 \u03b4\u03b9\u03b1\u03ba\u03cc\u03c0\u03c4\u03b5\u03c4\u03b5 \u03ba\u03b1\u03b9 \u03bc\u03b7 \u03be\u03b5\u03ba\u03b9\u03bd\u03ac\u03c4\u03b5 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03c5\u03bd\u03b5\u03bd\u03bd\u03cc\u03b7\u03c3\u03b7 \u03bc\u03b5 \u03b9\u03b1\u03c4\u03c1\u03cc. \u0397 \u03bb\u03af\u03c3\u03c4\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 17 ==================== --><\/p>\n<section id=\"section-17\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">17<\/span><\/span>\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/h2>\n<p>\u0397 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae. \u039f \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af \u03c4\u03b7 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b9\u03c3\u03c7\u03cd, \u03c4\u03b7\u03bd \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7, \u03c4\u03b7\u03bd \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae, \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03ac\u03c0\u03bf\u03c3\u03b7, \u03c4\u03b7\u03bd \u03bf\u03bc\u03b9\u03bb\u03af\u03b1, \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03bd\u03bf\u03ae \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c3\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1. \u039f\u03b9 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b2\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7.<\/p>\n<p>\u039f \u03c4\u03af\u03c4\u03bb\u03bf\u03c2 \u03c4\u03c9\u03bd AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b4\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03bc\u03b5\u03c4\u03c1\u03b9\u03ad\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03b5\u03c0\u03af\u03c3\u03ba\u03b5\u03c8\u03b7. \u03a3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03c4\u03af\u03c4\u03bb\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03b3\u03c1\u03b1\u03bc\u03bc\u03b9\u03ba\u03ae. \u0388\u03c4\u03c3\u03b9, \u03ad\u03bd\u03b1\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c7\u03c9\u03c1\u03af\u03c2 \u03b5\u03bd\u03c4\u03c5\u03c0\u03c9\u03c3\u03b9\u03b1\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ae \u03c4\u03bf\u03c5 \u03c4\u03af\u03c4\u03bb\u03bf\u03c5 \u03ae \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2 \u03c3\u03c4\u03bf\u03bd \u03c4\u03af\u03c4\u03bb\u03bf \u03c7\u03c9\u03c1\u03af\u03c2 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b7 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.<\/p>\n<p>\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03ba\u03bf\u03c1\u03c4\u03b9\u03ba\u03bf\u03c3\u03c4\u03b5\u03c1\u03bf\u03b5\u03b9\u03b4\u03ae \u03ae \u03b1\u03bd\u03bf\u03c3\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ac, \u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b3\u03b5\u03bd\u03b9\u03ba\u03ae \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ac \u03ad\u03bd\u03b6\u03c5\u03bc\u03b1, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7, \u03bb\u03b9\u03c0\u03af\u03b4\u03b9\u03b1 \u03ae \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03b3\u03c9\u03b3\u03ae. \u03a3\u03c4\u03cc\u03c7\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b9\u03c3\u03bf\u03c1\u03c1\u03bf\u03c0\u03af\u03b1 \u03b1\u03bd\u03ac\u03bc\u03b5\u03c3\u03b1 \u03c3\u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03c6\u03c5\u03b3\u03ae \u03b1\u03bd\u03b5\u03c0\u03b9\u03b8\u03cd\u03bc\u03b7\u03c4\u03c9\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03b5\u03b9\u03ce\u03bd.<\/p>\n<p>\u0397 \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03ae \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03af\u03b4\u03b9\u03bf \u03c4\u03bf\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9. \u0393\u03b9\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03b5\u03b9\u03b3\u03bc\u03b1, \u03c0\u03cc\u03c4\u03b5 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b2\u03bb\u03b5\u03c6\u03b1\u03c1\u03cc\u03c0\u03c4\u03c9\u03c3\u03b7, \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03c4\u03b7 \u03bc\u03ac\u03c3\u03b7\u03c3\u03b7 \u03c3\u03c4\u03bf \u03c4\u03ad\u03bb\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b3\u03b5\u03cd\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b1\u03bd \u03b7 \u03c6\u03c9\u03bd\u03ae \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03bf\u03bc\u03b9\u03bb\u03af\u03b1 \u03ae \u03b1\u03bd \u03b7 \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1. \u0391\u03c5\u03c4\u03ad\u03c2 \u03bf\u03b9 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c0\u03b9\u03bf \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b1\u03c0\u03cc \u03bc\u03af\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c4\u03b9\u03bc\u03ae \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 18 ==================== --><\/p>\n<section id=\"section-18\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">18<\/span><\/span>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03c0\u03b1\u03b3\u03af\u03b4\u03b5\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1<\/h2>\n<p>\u0397 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03c0\u03b1\u03b3\u03af\u03b4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c5\u03c0\u03b5\u03c1\u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b5\u03bd\u03cc\u03c2 \u03b8\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1. \u0391\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b1 AChR \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1, \u03ba\u03ac\u03b8\u03b5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03c4\u03bf \u03c3\u03c9\u03c3\u03c4\u03cc \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf.<\/p>\n<p>\u0397 \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03b3\u03af\u03b4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c5\u03c0\u03bf\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2. \u0391\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac AChR \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03bf\u03c5\u03bd \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1. \u0397 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 MuSK-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae, LRP4-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03ae \u03bf\u03c1\u03bf\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae. \u0391\u03c5\u03c4\u03cc \u03b9\u03c3\u03c7\u03cd\u03b5\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ae \u03bc\u03bf\u03c1\u03c6\u03ae \u03ae \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bd\u03c9\u03c1\u03af\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n<p>\u0397 \u03c4\u03c1\u03af\u03c4\u03b7 \u03c0\u03b1\u03b3\u03af\u03b4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03c9\u03bd. \u0391\u03bd \u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9 \u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2, \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03c4\u03bf cut-off. \u0393\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c4\u03ac\u03c3\u03b7\u03c2, \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c4\u03b9\u03bc\u03cc\u03c4\u03b5\u03c1\u03bf \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c4\u03bf \u03af\u03b4\u03b9\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03ae \u03c4\u03bf\u03c5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03bf\u03bd \u03b7 \u03af\u03b4\u03b9\u03b1 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2, \u03cc\u03c4\u03b1\u03bd \u03b1\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac \u03b5\u03c6\u03b9\u03ba\u03c4\u03cc.<\/p>\n<p>\u0397 \u03c4\u03ad\u03c4\u03b1\u03c1\u03c4\u03b7 \u03c0\u03b1\u03b3\u03af\u03b4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c0\u03b1\u03c1\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1. \u0388\u03bd\u03b1\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u00ab\u03c7\u03b5\u03b9\u03c1\u03bf\u03c4\u03b5\u03c1\u03b5\u03cd\u03b5\u03b9 \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2\u00bb, \u03b5\u03bd\u03ce \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03bb\u03ac\u03b2\u03b5\u03b9 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03b2\u03b1\u03c1\u03cd\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae \u03bc\u03b5\u03c4\u03ac\u03b4\u03bf\u03c3\u03b7.<\/p>\n<p>\u0397 \u03c0\u03ad\u03bc\u03c0\u03c4\u03b7 \u03c0\u03b1\u03b3\u03af\u03b4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c3\u03cd\u03b3\u03c7\u03c5\u03c3\u03b7 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2. \u0397 \u03b4\u03b9\u03c0\u03bb\u03c9\u03c0\u03af\u03b1, \u03b7 \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7, \u03b7 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03ae \u03b7 \u03b4\u03c5\u03c3\u03c6\u03b1\u03b3\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03b1\u03b9\u03c4\u03af\u03b5\u03c2. \u0398\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1, \u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03ba\u03ac \u03b5\u03c0\u03b5\u03b9\u03c3\u03cc\u03b4\u03b9\u03b1, \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b5\u03c2, \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03bd\u03b5\u03c5\u03c1\u03ce\u03bd\u03b1, \u03c0\u03b5\u03c1\u03b9\u03c6\u03b5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf Lambert-Eaton \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03c0\u03bf\u03c5\u03bd \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 19 ==================== --><\/p>\n<section id=\"section-19\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">19<\/span><\/span>\u03a0\u03cc\u03c4\u03b5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7;<\/h2>\n<p>\u0397 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ae\u03c0\u03b9\u03b1, \u03b1\u03bb\u03bb\u03ac \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03c9\u03b8\u03b5\u03af \u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03b1. \u0397 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b2\u03bf\u03bb\u03b2\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 \u03c0\u03b9\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03b5\u03c1\u03bf\u03cd\u03bd. \u039f \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b6\u03b7\u03c4\u03ae\u03c3\u03b5\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03cc\u03c4\u03b1\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1, \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03ac\u03c0\u03bf\u03c3\u03b7 \u03ae \u03c4\u03b1\u03c7\u03b5\u03af\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1\u03c2.<\/p>\n<ul>\n<li>\u0394\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1, \u03bf\u03c1\u03b8\u03cc\u03c0\u03bd\u03bf\u03b9\u03b1 \u03ae \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03cc\u03c4\u03b9 \u03b7 \u03b1\u03bd\u03b1\u03c0\u03bd\u03bf\u03ae \u03ba\u03bf\u03c5\u03c1\u03ac\u03b6\u03b5\u03b9.<\/li>\n<li>\u0391\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03ba\u03b1\u03c4\u03ac\u03c0\u03bf\u03c3\u03b7\u03c2 \u03c5\u03b3\u03c1\u03ce\u03bd \u03ae \u03c4\u03c1\u03bf\u03c6\u03ae\u03c2.<\/li>\n<li>\u03a0\u03bd\u03b9\u03b3\u03bc\u03bf\u03bd\u03ae, \u03b2\u03ae\u03c7\u03b1\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c4\u03bf \u03c6\u03b1\u03b3\u03b7\u03c4\u03cc \u03ae \u03b5\u03b9\u03c3\u03c1\u03cc\u03c6\u03b7\u03c3\u03b7.<\/li>\n<li>\u0391\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03bd\u03b1 \u03ba\u03c1\u03b1\u03c4\u03b7\u03b8\u03b5\u03af \u03c4\u03bf \u03ba\u03b5\u03c6\u03ac\u03bb\u03b9.<\/li>\n<li>\u03a4\u03b1\u03c7\u03b5\u03af\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c6\u03c9\u03bd\u03ae\u03c2, \u03bf\u03bc\u03b9\u03bb\u03af\u03b1\u03c2 \u03ae \u03bc\u03ac\u03c3\u03b7\u03c3\u03b7\u03c2.<\/li>\n<li>\u039d\u03ad\u03b1 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7, \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b5\u03af\u03bf \u03ae \u03bd\u03ad\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf.<\/li>\n<\/ul>\n<div style=\"background: #fef2f2; border-left: 4px solid #b91c1c; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\"><strong>\u03a0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae:<\/strong> \u0397 \u03bc\u03c5\u03b1\u03c3\u03b8\u03b5\u03bd\u03b9\u03ba\u03ae \u03ba\u03c1\u03af\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03b5\u03af\u03b3\u03bf\u03c5\u03c3\u03b1 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7. \u0397 \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1 \u03ae \u03b7 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b7 \u03b4\u03c5\u03c3\u03ba\u03b1\u03c4\u03b1\u03c0\u03bf\u03c3\u03af\u03b1 \u03c3\u03b5 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae \u03ae \u03cd\u03c0\u03bf\u03c0\u03c4\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 20 ==================== --><\/p>\n<section id=\"section-20\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">20<\/span><\/span>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b5\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR;<\/summary>\n<p>\u038c\u03c7\u03b9, \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c0\u03bb\u03ae \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0391\u03bd \u03c4\u03b1 AChR \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac, \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1;<\/summary>\n<p>\u038c\u03c7\u03b9, \u03b3\u03b9\u03b1\u03c4\u03af \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 AChR-\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae, MuSK-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae, LRP4-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03ae \u03bf\u03c1\u03bf\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc AChR \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1;<\/summary>\n<p>\u03a3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ac \u03bc\u03b5 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1, \u03b5\u03c6\u03cc\u03c3\u03bf\u03bd \u03c4\u03b1\u03b9\u03c1\u03b9\u03ac\u03b6\u03b5\u03b9 \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03bb\u03ad\u03b3\u03be\u03c9 MuSK \u03ba\u03b1\u03b9 LRP4 \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 AChR;<\/summary>\n<p>\u039f \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 MuSK \u03ba\u03b1\u03b9 LRP4 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf\u03c2 \u03cc\u03c4\u03b1\u03bd \u03c4\u03b1 AChR \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b1\u03bb\u03bb\u03ac \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039f \u03c4\u03af\u03c4\u03bb\u03bf\u03c2 \u03c4\u03c9\u03bd AChR \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03c0\u03cc\u03c3\u03bf \u03b2\u03b1\u03c1\u03b9\u03ac \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2;<\/summary>\n<p>\u038c\u03c7\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1, \u03b3\u03b9\u03b1\u03c4\u03af \u03b7 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03b5\u03ba\u03c4\u03b9\u03bc\u03ac\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1;<\/summary>\n<p>\u039d\u03b1\u03b9, \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 IVIG, \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c6\u03b1\u03af\u03c1\u03b5\u03c3\u03b7, rituximab \u03ba\u03b1\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf\u03c5\u03c2 \u03c4\u03af\u03c4\u03bb\u03bf\u03c5\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0398\u03b5\u03c4\u03b9\u03ba\u03ac AChR \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03ad\u03c7\u03c9 \u03b8\u03cd\u03bc\u03c9\u03bc\u03b1;<\/summary>\n<p>\u038c\u03c7\u03b9, \u03b1\u03bb\u03bb\u03ac \u03c3\u03b5 AChR-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c3\u03c5\u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b8\u03ce\u03c1\u03b1\u03ba\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b8\u03cd\u03bc\u03bf\u03c5.<\/p>\n<\/details>\n<\/section>\n<p><!-- ==================== SECTION 21 ==================== --><\/p>\n<section id=\"section-21\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">21<\/span><\/span>\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/h2>\n<p>\u03a4\u03b1 <strong>\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 gravis. \u0397 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03ac \u03c4\u03bf\u03c5\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1, \u03b1\u03bb\u03bb\u03ac \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03bc\u03b5 \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7.<\/p>\n<p>\u0391\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac AChR \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03bf\u03c5\u03bd \u03c4\u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1. \u0391\u03bd \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03c5\u03c0\u03b9\u03ba\u03ae, \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b5\u03c7\u03b9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 <strong>MuSK<\/strong>, <strong>LRP4<\/strong>, cell-based assay \u03ae \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03c9\u03c2 single-fiber EMG.<\/p>\n<p>\u0388\u03bd\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03c0\u03b9\u03bf \u03bf\u03c1\u03b3\u03b1\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf: \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7, \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03b8\u03ce\u03c1\u03b1\u03ba\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03b8\u03cd\u03bc\u03bf, \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c3\u03c5\u03bd\u03bf\u03b4\u03ce\u03bd \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03c9\u03bd \u03bd\u03bf\u03c3\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc. \u0397 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03bd\u03cc\u03c3\u03bf\u03c2, \u03b1\u03bb\u03bb\u03ac \u03bc\u03b5 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bb\u03b5\u03b3\u03c7\u03b8\u03b5\u03af \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac.<\/p>\n<p>\u0397 \u03c0\u03b9\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1 \u03bc\u03b7 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03bd\u03b5\u03af\u03c2 \u03c3\u03b5 \u03bc\u03af\u03b1 \u03bc\u03cc\u03bd\u03bf \u03c4\u03b9\u03bc\u03ae. \u0397 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc, \u03c3\u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7, \u03c3\u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2. \u03a4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd\u03c4\u03b9\u03bc\u03bf \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03bf, \u03cc\u03c7\u03b9 \u03b1\u03c0\u03bf\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 22 ==================== --><\/p>\n<section id=\"section-22\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 42px; height: 42px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#7f1d1d 0%,#b70000 100%); border-radius: 10px; box-shadow: 0 8px 18px rgba(127,29,29,0.28); flex: 0 0 42px;\"><span style=\"transform: rotate(-45deg); color: #fff; font-size: 15px; font-weight: 800; line-height: 1;\">22<\/span><\/span>\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 &amp; \u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/h2>\n<p style=\"text-align: center; margin: 12px 0 14px;\"><strong>\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03b9\u03b1\u03c4\u03c1\u03cc \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03cc \u03bc\u03b1\u03c2.<\/strong> \u039c\u03c0\u03bf\u03c1\u03b5\u03af\u03c4\u03b5 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03c3\u03b5\u03c4\u03b5 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ae \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.<\/p>\n<div style=\"background: #fdf2f2; border: 2px solid #b70000; border-radius: 14px; padding: 18px; text-align: center;\">\n<div><strong>\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd AChR, MuSK \u03ae LRP4 \u03ae \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf:<\/strong><\/div>\n<div style=\"display: flex; gap: 10px; justify-content: center; flex-wrap: wrap; margin-top: 10px;\"><a style=\"background: #b70000; color: #fff; padding: 12px 18px; border-radius: 12px; text-decoration: none; font-weight: 600; display: inline-flex; align-items: center; justify-content: center; width: 200px; height: 44px; white-space: nowrap;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"noopener\">\ud83d\udcd8 \u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd<\/a><br \/>\n<a style=\"background: #b70000; color: #fff; padding: 12px 18px; border-radius: 12px; text-decoration: none; font-weight: 600; display: inline-flex; align-items: center; justify-content: center; width: 200px; height: 44px; white-space: nowrap;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/about-us\/appointments\/\" target=\"_blank\" rel=\"nofollow noopener\">\ud83d\udcc5 \u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd<\/a><\/div>\n<div style=\"margin-top: 10px; color: #374151;\">\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n<\/div>\n<h3 style=\"margin: 24px 0 10px; font-size: 20px; font-weight: 800; color: #111827;\">\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1 &amp; \u03a0\u03b7\u03b3\u03ad\u03c2<\/h3>\n<div style=\"margin-top: 12px; font-size: 14px; line-height: 1.35;\">\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0;\">Narayanaswami P, Sanders DB, Wolfe G, et al. International Consensus Guidance for Management of Myasthenia Gravis: 2020 Update. <em>Neurology<\/em>.<br \/>\n<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7884987\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7884987\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0;\">Shelly S, et al. National guidelines for diagnosis, treatment and management of myasthenia gravis. <em>Therapeutic Advances in Neurological Disorders<\/em>.<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0;\">Jacob S, Farrugia ME, Hewamadduma C, et al. Association of British Neurologists autoimmune myasthenia gravis management guidelines 2025 update. <em>Practical Neurology<\/em>.<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0;\">Lazaridis K, Tzartos SJ. Autoantibody Specificities in Myasthenia Gravis. <em>Frontiers in Immunology<\/em>.<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0;\">Gilhus NE. Myasthenia Gravis. <em>New England Journal of Medicine<\/em>.<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0;\">\u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u2013 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u039b\u03b1\u03bc\u03af\u03b1<br \/>\n<a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"noopener\">https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/<\/a><\/div>\n<\/div>\n<div style=\"background: #f1f5f9; border-left: 4px solid #2563eb; padding: 10px 14px; border-radius: 8px; margin-top: 18px;\"><strong style=\"color: #1d4ed8;\">\u0395\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03bc\u03ad\u03bb\u03b5\u03b9\u03b1:<\/strong><br \/>\n\u0394\u03c1. \u03a0\u03b1\u03bd\u03c4\u03b5\u03bb\u03ae\u03c2 \u0391\u03bd\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03cc\u03c0\u03bf\u03c5\u03bb\u03bf\u03c2<br \/>\n\u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u039b\u03b1\u03bc\u03af\u03b1\u03c2<br \/>\n\u0388\u03c3\u03bb\u03b9\u03bd 19, \u039b\u03b1\u03bc\u03af\u03b1 35100 \u2022 \u03a4\u03b7\u03bb. +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>\u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR, MuSK \u03ba\u03b1\u03b9 LRP4: \u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u039c\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1 Gravis \u0394\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7: 31 \u039f\u03ba\u03c4\u03c9\u03b2\u03c1\u03af\u03bf\u03c5 2025 \u2022 \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7: 24 \u0391\u03c0\u03c1\u03b9\u03bb\u03af\u03bf\u03c5 2026 \u03a3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7 \u03c0\u03b5\u03c1\u03af\u03bb\u03b7\u03c8\u03b7: \u03a4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 AChR \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u039c\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 Gravis, \u03bc\u03b9\u03b1\u03c2 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03c3\u03cd\u03bd\u03b1\u03c8\u03b7\u03c2. \u038c\u03c4\u03b1\u03bd \u03c4\u03b1 AChR \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b1\u03bb\u03bb\u03ac \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd \u03cd\u03c0\u03bf\u03c0\u03c4\u03b1, \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b5\u03c0\u03b5\u03ba\u03c4\u03b5\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":6700,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2534],"tags":[2360,985,2361,376,1651,991,2286,2362,2363],"class_list":["post-6699","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exetaseis-aimatos","tag-achr","tag-lrp4","tag-musk","tag-antisomata","tag-mikroviologiko-lamia","tag-myastheneia-gravis","tag-nevrologia","tag-nevromyikes-pathiseis","tag-ofthalmiki-myastheneia"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/6699","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/comments?post=6699"}],"version-history":[{"count":4,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/6699\/revisions"}],"predecessor-version":[{"id":11225,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/6699\/revisions\/11225"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media\/6700"}],"wp:attachment":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media?parent=6699"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/categories?post=6699"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/tags?post=6699"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}