{"id":6635,"date":"2025-10-22T10:10:25","date_gmt":"2025-10-22T07:10:25","guid":{"rendered":"https:\/\/mikrobiologikolamia.gr\/staging\/?p=6635"},"modified":"2026-04-04T13:31:16","modified_gmt":"2026-04-04T10:31:16","slug":"skliroderma-systimatiki-sklirynsi","status":"publish","type":"post","link":"https:\/\/mikrobiologikolamia.gr\/staging\/skliroderma-systimatiki-sklirynsi\/","title":{"rendered":"\u03a3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 (\u03a3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03a3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7) \u2013 \u03a3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u0394\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 &#038; \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 | \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u039b\u03b1\u03bc\u03af\u03b1"},"content":{"rendered":"<article lang=\"el\" style=\"font-family: system-ui,-apple-system,Segoe UI,Roboto,Helvetica,Arial,sans-serif; line-height: 1.7; color: #111827; max-width: 900px; margin: 0 auto;\">\n<h1 style=\"font-size: 44px; line-height: 1.15; font-weight: 800; margin: 0 0 14px; color: #111827;\">\u03a3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 (\u03a3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03a3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7): \u03a3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1, \u0395\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1<\/h1>\n<div style=\"margin: 10px 0 12px; font-size: 13px; color: #6b7280;\">\u0394\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7: <time datetime=\"2025-10-22\">22 \u039f\u03ba\u03c4\u03c9\u03b2\u03c1\u03af\u03bf\u03c5 2025<\/time> \u2022 \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7: <time datetime=\"2026-04-04\">4 \u0391\u03c0\u03c1\u03b9\u03bb\u03af\u03bf\u03c5 2026<\/time><\/div>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0 18px;\">\n<p><strong>\u03a3\u03cd\u03bd\u03bf\u03c8\u03b7 \u03c3\u03b5 30\u2033<\/strong><\/p>\n<p style=\"margin: 8px 0 0; line-height: 1.7;\">\u03a4\u03bf <strong>\u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1<\/strong> \u03ae <strong>\u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 <strong>\u03c7\u03c1\u03cc\u03bd\u03b9\u03bf \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1<\/strong> \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03ac\u03b6\u03b5\u03b9 <strong>\u03b2\u03bb\u03ac\u03b2\u03b7 \u03bc\u03b9\u03ba\u03c1\u03ce\u03bd \u03b1\u03b3\u03b3\u03b5\u03af\u03c9\u03bd<\/strong>, <strong>\u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7<\/strong> \u03ba\u03b1\u03b9 <strong>\u03af\u03bd\u03c9\u03c3\u03b7<\/strong>. \u0394\u03b5\u03bd \u03b1\u03c6\u03bf\u03c1\u03ac \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1. \u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 <strong>\u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2, \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac, \u03bd\u03b5\u03c6\u03c1\u03bf\u03cd\u03c2, \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc<\/strong> \u03ba\u03b1\u03b9 \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b1 \u03ae \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b1 \u03b1\u03b3\u03b3\u03b5\u03af\u03b1. \u03a4\u03b1 \u03c0\u03b9\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u00ab\u03c0\u03c1\u03ce\u03b9\u03bc\u03b1 \u03ba\u03b1\u03bc\u03c0\u03b1\u03bd\u03ac\u03ba\u03b9\u03b1\u00bb \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf <strong>\u03c6\u03b1\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf Raynaud<\/strong>, \u03c4\u03bf <strong>\u03c0\u03c1\u03ae\u03be\u03b9\u03bc\u03bf\/\u03c3\u03c6\u03af\u03be\u03b9\u03bc\u03bf \u03b4\u03b1\u03ba\u03c4\u03cd\u03bb\u03c9\u03bd<\/strong>, \u03b7 <strong>\u03c0\u03b1\u03bb\u03b9\u03bd\u03b4\u03c1\u03cc\u03bc\u03b7\u03c3\u03b7<\/strong>, \u03b7 <strong>\u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1<\/strong> \u03ba\u03b1\u03b9 \u03c4\u03b1 <strong>\u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong> \u03cc\u03c0\u03c9\u03c2 <strong>anti-centromere<\/strong>, <strong>anti\u2013Scl-70<\/strong> \u03ba\u03b1\u03b9 <strong>anti\u2013RNA polymerase III<\/strong>. \u0397 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03ba\u03ac\u03bd\u03bf\u03c5\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7.<\/p>\n<\/div>\n<nav id=\"toc\" style=\"background: #f9fafb; border: 1px solid #e5e7eb; border-radius: 14px; padding: 14px 16px; margin: 14px 0 10px;\" aria-label=\"\u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1\"><strong>\u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1<\/strong><\/p>\n<ol style=\"margin: 10px 0 0 18px; padding: 0; line-height: 1.9;\">\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-1\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-2\">\u03a0\u03ce\u03c2 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af\u03c4\u03b1\u03b9 \u2013 \u03b1\u03b3\u03b3\u03b5\u03af\u03b1, \u03b1\u03bd\u03bf\u03c3\u03af\u03b1, \u03af\u03bd\u03c9\u03c3\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-3\">\u03a0\u03bf\u03b9\u03bf\u03b9 \u03c4\u03cd\u03c0\u03bf\u03b9 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-4\">\u03a0\u03bf\u03b9\u03bf\u03b9 \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf\u03b9 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03bf\u03c5\u03bd \u03bd\u03cc\u03c3\u03bf<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-5\">\u03a0\u03c1\u03ce\u03b9\u03bc\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03b3\u03bd\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-6\">\u03a4\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03c3\u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1, \u03c3\u03c4\u03b1 \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03b5\u03af\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-7\">\u03a0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c0\u03bd\u03bf\u03ae: \u03b3\u03b9\u03b1\u03c4\u03af \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03cc\u03c3\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03bf\u03af<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-8\">\u039a\u03b1\u03c1\u03b4\u03b9\u03ac, \u03bd\u03b5\u03c6\u03c1\u03bf\u03af \u03ba\u03b1\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-9\">\u039f\u03b9\u03c3\u03bf\u03c6\u03ac\u03b3\u03bf\u03c2, \u03c3\u03c4\u03bf\u03bc\u03ac\u03c7\u03b9 \u03ba\u03b1\u03b9 \u03ad\u03bd\u03c4\u03b5\u03c1\u03bf<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-10\">\u03a0\u03ce\u03c2 \u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-11\">\u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-12\">\u0391\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-13\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-14\">\u0392\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c1\u03c7\u03ad\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-15\">\u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b1\u03bd\u03ac \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03cc\u03c1\u03b3\u03b1\u03bd\u03bf<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-16\">\u039a\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1, \u03ba\u03c1\u03cd\u03bf, \u03b4\u03ad\u03c1\u03bc\u03b1, \u03ac\u03c3\u03ba\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-17\">\u0395\u03c1\u03b3\u03b1\u03c3\u03af\u03b1, \u03c3\u03c7\u03ad\u03c3\u03b5\u03b9\u03c2, \u03c8\u03c5\u03c7\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-18\">\u03a3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-19\">\u03a0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03ac\u03bd\u03bf \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-20\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b5\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-21\">\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section-22\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03c1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd &amp; \u03b2\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/a><\/li>\n<\/ol>\n<\/nav>\n<hr style=\"border: none; border-top: 2px solid #d1d5db; margin: 12px 0 22px;\" \/>\n<p><!-- ==================== SECTION 1 ==================== --><\/p>\n<section id=\"section-1\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">1<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1<\/span><\/h2>\n<p>\u03a4\u03bf <strong>\u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1<\/strong>, \u03c0\u03bf\u03c5 \u03c3\u03c4\u03b7\u03bd \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03bf\u03c1\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03bb\u03ad\u03b3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 <strong>\u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7<\/strong> \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd, \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 <strong>\u03c3\u03c0\u03ac\u03bd\u03b9\u03bf \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03b9\u03c3\u03c4\u03bf\u03cd<\/strong>. \u03a4\u03bf \u03cc\u03bd\u03bf\u03bc\u03ac \u03c4\u03bf\u03c5 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03ba\u03c5\u03c1\u03b9\u03bf\u03bb\u03b5\u03ba\u03c4\u03b9\u03ba\u03ac \u00ab\u03c3\u03ba\u03bb\u03b7\u03c1\u03cc \u03b4\u03ad\u03c1\u03bc\u03b1\u00bb, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03c0\u03bf\u03bb\u03bb\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03c0\u03ac\u03c7\u03c5\u03bd\u03c3\u03b7, \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7 \u03ae \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u00ab\u03c4\u03c1\u03b1\u03b2\u03ae\u03b3\u03bc\u03b1\u03c4\u03bf\u03c2\u00bb \u03c3\u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1. \u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03cc\u03bc\u03c9\u03c2 \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03c0\u03b9\u03bf \u03c3\u03cd\u03bd\u03b8\u03b5\u03c4\u03b7: \u03b1\u03c6\u03bf\u03c1\u03ac <strong>\u03c4\u03b1 \u03b1\u03b3\u03b3\u03b5\u03af\u03b1<\/strong>, \u03c4\u03bf <strong>\u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03cc<\/strong> \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 <strong>\u03ba\u03bf\u03bb\u03bb\u03b1\u03b3\u03cc\u03bd\u03bf\u03c5<\/strong>, \u03ba\u03b1\u03b9 \u03b3\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1 \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 <strong>\u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2, \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac, \u03bd\u03b5\u03c6\u03c1\u03bf\u03cd\u03c2, \u03bf\u03b9\u03c3\u03bf\u03c6\u03ac\u03b3\u03bf \u03ba\u03b1\u03b9 \u03ad\u03bd\u03c4\u03b5\u03c1\u03bf<\/strong>.<\/p>\n<p>\u0397 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03af\u03b4\u03b9\u03b1 \u03c3\u03b5 \u03cc\u03bb\u03bf\u03c5\u03c2. \u03a5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 <strong>Raynaud<\/strong> \u03ba\u03b1\u03b9 \u03ae\u03c0\u03b9\u03b5\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03c3\u03b5\u03b9\u03c2, \u03b5\u03bd\u03ce \u03ac\u03bb\u03bb\u03bf\u03b9 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03c0\u03b9\u03bf \u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03b1 <strong>\u03b4\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae<\/strong> \u03ae \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03c0\u03c1\u03bf\u03c3\u03b2\u03bf\u03bb\u03ae \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd. \u0391\u03c5\u03c4\u03cc\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03bb\u03cc\u03b3\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03bc\u03af\u03b1 \u00ab\u03bc\u03bf\u03bd\u03bf\u03ba\u03cc\u03bc\u03bc\u03b1\u03c4\u03b7\u00bb \u03c0\u03ac\u03b8\u03b7\u03c3\u03b7. \u0395\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 <strong>\u03c6\u03ac\u03c3\u03bc\u03b1<\/strong> \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03bc\u03b5 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c1\u03c5\u03b8\u03bc\u03bf\u03cd\u03c2 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2, \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ce\u03bd.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0 16px;\"><strong>\u03a4\u03b9 \u03bd\u03b1 \u03ba\u03c1\u03b1\u03c4\u03ae\u03c3\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03c1\u03c7\u03ae:<\/strong> \u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 <strong>\u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b4\u03bf\u03c4\u03b9\u03ba\u03cc<\/strong>, <strong>\u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bb\u03bb\u03b5\u03c1\u03b3\u03af\u03b1<\/strong> \u03ba\u03b1\u03b9 <strong>\u03b4\u03b5\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1<\/strong>. \u03a4\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03bf \u03b2\u03ae\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03b9\u03c3\u03c4\u03b5\u03af \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b1 \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9 \u03c3\u03c9\u03c3\u03c4\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 2 ==================== --><\/p>\n<section id=\"section-2\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">2<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03ce\u03c2 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af\u03c4\u03b1\u03b9 \u2013 \u03b1\u03b3\u03b3\u03b5\u03af\u03b1, \u03b1\u03bd\u03bf\u03c3\u03af\u03b1, \u03af\u03bd\u03c9\u03c3\u03b7<\/span><\/h2>\n<p>\u0397 \u03c0\u03b1\u03b8\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03ba\u03bb\u03b7\u03c1\u03bf\u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b5\u03be\u03b7\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b1 \u03b1\u03bd \u03c3\u03ba\u03b5\u03c6\u03c4\u03b5\u03af\u03c4\u03b5 \u03c4\u03c1\u03b5\u03b9\u03c2 \u03b4\u03b9\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03bf\u03cd\u03bd \u03c4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b1. \u03a0\u03c1\u03ce\u03c4\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 <strong>\u03b2\u03bb\u03ac\u03b2\u03b7 \u03c3\u03c4\u03b1 \u03bc\u03b9\u03ba\u03c1\u03ac \u03b1\u03b3\u03b3\u03b5\u03af\u03b1<\/strong>. \u03a4\u03b1 \u03b1\u03b3\u03b3\u03b5\u03af\u03b1 \u03b3\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b5\u03c5\u03b5\u03c1\u03ad\u03b8\u03b9\u03c3\u03c4\u03b1, \u03c3\u03c5\u03c3\u03c0\u03ce\u03bd\u03c4\u03b1\u03b9 \u03c5\u03c0\u03b5\u03c1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03bc\u03b9\u03ba\u03c1\u03bf\u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03af\u03b1. \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03b1\u03c5\u03c4\u03cc \u03b5\u03ba\u03c6\u03c1\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bc\u03b5 <strong>\u03c6\u03b1\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf Raynaud<\/strong>, \u03ba\u03c1\u03cd\u03b1 \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1, \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c7\u03c1\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03b5\u03c1\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c0\u03bf\u03cd\u03bb\u03c9\u03c3\u03b7 \u03ae \u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03b9\u03ba\u03ac \u03ad\u03bb\u03ba\u03b7.<\/p>\n<p>\u03a0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c4\u03bf <strong>\u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1<\/strong>. \u039f \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03b9 <strong>\u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong> \u03ba\u03b1\u03b9 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03bc\u03b5\u03c3\u03bf\u03bb\u03b1\u03b2\u03b7\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03ac\u03c3\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b9\u03c3\u03bf\u03c1\u03c1\u03bf\u03c0\u03af\u03b1 \u03c4\u03c9\u03bd \u03b9\u03c3\u03c4\u03ce\u03bd. \u0391\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03b2\u03bb\u03ac\u03b2\u03b7, \u03b1\u03bb\u03bb\u03ac \u03cc\u03c4\u03b9 \u03b7 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03b3\u03c1\u03b1\u03c6\u03ae \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03b2\u03bf\u03b7\u03b8\u03ac \u03bd\u03b1 \u03ba\u03b1\u03c4\u03b1\u03bb\u03ac\u03b2\u03bf\u03c5\u03bc\u03b5 <strong>\u03c4\u03b9 \u03c4\u03cd\u03c0\u03bf \u03bd\u03cc\u03c3\u03bf\u03c5<\/strong> \u03ad\u03c7\u03b5\u03b9 \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03ba\u03b1\u03b9 <strong>\u03c0\u03bf\u03b9\u03b1 \u03cc\u03c1\u03b3\u03b1\u03bd\u03b1<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03bf\u03cd\u03bd \u03c3\u03c4\u03b5\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7.<\/p>\n<p>\u03a4\u03bf \u03c4\u03c1\u03af\u03c4\u03bf \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 <strong>\u03af\u03bd\u03c9\u03c3\u03b7<\/strong>. \u039f\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1, \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b9\u03bd\u03bf\u03b2\u03bb\u03ac\u03c3\u03c4\u03b5\u03c2, \u00ab\u03b4\u03bf\u03c5\u03bb\u03b5\u03cd\u03bf\u03c5\u03bd \u03c5\u03c0\u03b5\u03c1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ac\u00bb \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03ba\u03bf\u03bb\u03bb\u03b1\u03b3\u03cc\u03bd\u03bf \u03b1\u03c0\u03cc \u03cc\u03c3\u03bf \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9. \u03a4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03c0\u03ac\u03c7\u03c5\u03bd\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7 \u03b9\u03c3\u03c4\u03ce\u03bd<\/strong>. \u03a3\u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03c3\u03c6\u03af\u03be\u03b9\u03bc\u03bf, \u03b3\u03c5\u03b1\u03bb\u03ac\u03b4\u03b1 \u03ae \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b5\u03bb\u03b1\u03c3\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1. \u03a3\u03c4\u03bf\u03c5\u03c2 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2, \u03b1\u03bd \u03c0\u03c1\u03bf\u03c7\u03c9\u03c1\u03ae\u03c3\u03b5\u03b9, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 <strong>\u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1<\/strong> \u03ba\u03b1\u03b9 \u03c0\u03c4\u03ce\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b5\u03c6\u03b5\u03b4\u03c1\u03b5\u03af\u03b1\u03c2.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7, \u03ba\u03b1\u03bd\u03ad\u03bd\u03b1\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ce\u03c2 \u03c4\u03bf \u03af\u03b4\u03b9\u03bf \u00ab\u03bc\u03b5\u03af\u03b3\u03bc\u03b1\u00bb \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1\u03c2, \u03b1\u03bd\u03bf\u03c3\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03af\u03bd\u03c9\u03c3\u03b7\u03c2. \u03a3\u03b5 \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf\u03bd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03b5\u03af \u03b7 \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf\u03c2 \u03bc\u03b5 Raynaud \u03ba\u03b1\u03b9 \u03a0\u0391\u03a5. \u03a3\u03b5 \u03ac\u03bb\u03bb\u03bf\u03bd \u03b7 \u03b9\u03bd\u03c9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bd\u03b9\u03c3\u03c4\u03ce\u03c3\u03b1 \u03bc\u03b5 \u03b4\u03ad\u03c1\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2. \u0391\u03c5\u03c4\u03ae \u03b7 \u03b5\u03c4\u03b5\u03c1\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03b5\u03be\u03b7\u03b3\u03b5\u03af \u03b3\u03b9\u03b1\u03c4\u03af \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c3\u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7<\/strong> \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03af\u03b4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03cc\u03bb\u03bf\u03c5\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 3 ==================== --><\/p>\n<section id=\"section-3\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">3<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03bf\u03b9\u03bf\u03b9 \u03c4\u03cd\u03c0\u03bf\u03b9 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd<\/span><\/h2>\n<p>\u0397 \u03c0\u03b9\u03bf \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b4\u03b9\u03ac\u03ba\u03c1\u03b9\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03ac\u03bc\u03b5\u03c3\u03b1 \u03c3\u03b5 <strong>\u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7<\/strong> \u03ba\u03b1\u03b9 <strong>\u03b4\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7<\/strong>. \u0397 \u03b4\u03b9\u03ac\u03ba\u03c1\u03b9\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ae \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c9\u03c1\u03b7\u03c4\u03b9\u03ba\u03ae. \u0395\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf \u03c4\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5\u03bc\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf, \u03c0\u03bf\u03b9\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03bf\u03b9\u03b1 \u03cc\u03c1\u03b3\u03b1\u03bd\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b9\u03bf \u03c3\u03c4\u03b5\u03bd\u03ac.<\/p>\n<h3 style=\"font-size: 20px; margin: 18px 0 8px;\">\u03a0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03bc\u03bf\u03c1\u03c6\u03ae<\/h3>\n<p>\u03a3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03bc\u03bf\u03c1\u03c6\u03ae \u03b7 \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c6\u03bf\u03c1\u03ac \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 <strong>\u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1, \u03c7\u03ad\u03c1\u03b9\u03b1, \u03b1\u03bd\u03c4\u03b9\u03b2\u03c1\u03ac\u03c7\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03cc\u03c3\u03c9\u03c0\u03bf<\/strong>. \u03a3\u03c5\u03c7\u03bd\u03ac \u03c0\u03c1\u03bf\u03b7\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf \u03b4\u03b9\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1 \u03c4\u03bf Raynaud. \u0391\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 <strong>anti-centromere<\/strong> \u03b1\u03bd\u03ae\u03ba\u03bf\u03c5\u03bd \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1. \u0397 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b2\u03c1\u03b1\u03b4\u03cd\u03c4\u03b5\u03c1\u03b7, \u03b1\u03bb\u03bb\u03ac \u03b1\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b1\u03b8\u03ce\u03b1 \u03bd\u03cc\u03c3\u03bf. \u039c\u03b5 \u03c4\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03b3\u03b9\u03b1 <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7<\/strong>, \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ac \u03c0\u03c1\u03bf\u03b2\u03bb\u03ae\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03b9\u03ba\u03ac \u03ad\u03bb\u03ba\u03b7.<\/p>\n<h3 style=\"font-size: 20px; margin: 18px 0 8px;\">\u0394\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03bc\u03bf\u03c1\u03c6\u03ae<\/h3>\n<p>\u03a3\u03c4\u03b7 \u03b4\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03bc\u03bf\u03c1\u03c6\u03ae \u03b7 \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7 \u03b5\u03c0\u03b5\u03ba\u03c4\u03b5\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b9\u03bf \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03ac, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03c3\u03b5 <strong>\u03b2\u03c1\u03b1\u03c7\u03af\u03bf\u03bd\u03b5\u03c2, \u03bc\u03b7\u03c1\u03bf\u03cd\u03c2 \u03ae \u03ba\u03bf\u03c1\u03bc\u03cc<\/strong>. \u0397 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c0\u03b9\u03bf \u03b5\u03bd\u03b5\u03c1\u03b3\u03ae \u03c3\u03c4\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b3\u03b9\u03b1 <strong>\u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03c0\u03c1\u03bf\u03c3\u03b2\u03bf\u03bb\u03ae \u03c0\u03bd\u03b5\u03c5\u03bc\u03cc\u03bd\u03c9\u03bd, \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac\u03c2 \u03ae \u03bd\u03b5\u03c6\u03c1\u03ce\u03bd<\/strong>. \u03a4\u03b1 <strong>anti\u2013Scl-70<\/strong> \u03ba\u03b1\u03b9 <strong>anti\u2013RNA polymerase III<\/strong> \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03b4\u03ce. \u0395\u03b9\u03b4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b4\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03bc\u03bf\u03c1\u03c6\u03ae, \u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae.<\/p>\n<h3 style=\"font-size: 20px; margin: 18px 0 8px;\">Sine scleroderma \u03ba\u03b1\u03b9 overlap \u03bc\u03bf\u03c1\u03c6\u03ad\u03c2<\/h3>\n<p>\u03a5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c3\u03c0\u03b1\u03bd\u03b9\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03bf\u03c5 \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03ad\u03c7\u03b5\u03b9 <strong>\u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c7\u03c9\u03c1\u03af\u03c2 \u03b5\u03bc\u03c6\u03b1\u03bd\u03ae \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2<\/strong> \u03ae \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b7 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03c0\u03ac\u03b8\u03b7\u03c3\u03b7, \u03cc\u03c0\u03c9\u03c2 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1 \u03ae \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf Sj\u00f6gren. \u0391\u03c5\u03c4\u03ad\u03c2 \u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c0\u03b9\u03bf \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1.<\/p>\n<h3 style=\"font-size: 20px; margin: 18px 0 8px;\">\u039c\u03bf\u03c1\u03c6\u03ad\u03b1 \/ \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1<\/h3>\n<p>\u0397 <strong>\u03bc\u03bf\u03c1\u03c6\u03ad\u03b1<\/strong> \u03ae \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03bf\u03bd\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1. \u03a0\u03c1\u03bf\u03c3\u03b2\u03ac\u03bb\u03bb\u03b5\u03b9 \u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1 \u03c3\u03b5 \u03c0\u03bb\u03ac\u03ba\u03b5\u03c2 \u03ae \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03ba\u03b1\u03b9 <strong>\u03b4\u03b5\u03bd \u03c4\u03b1\u03c5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9<\/strong> \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7. \u0395\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03bd\u03b1 \u03bc\u03b7 \u03bc\u03c0\u03b5\u03c1\u03b4\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03bf\u03b9 \u03b4\u03cd\u03bf \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03b3\u03b9\u03b1\u03c4\u03af \u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae\u03c2 \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd \u03ba\u03b1\u03b9 \u03bf \u03c4\u03c1\u03cc\u03c0\u03bf\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03af\u03b4\u03b9\u03bf\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 4 ==================== --><\/p>\n<section id=\"section-4\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">4<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03bf\u03b9\u03bf\u03b9 \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf\u03b9 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03bf\u03c5\u03bd \u03bd\u03cc\u03c3\u03bf<\/span><\/h2>\n<p>\u03a4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03bd\u03cc\u03c3\u03bf\u03c2<\/strong> \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 <strong>\u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2<\/strong>, \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b5\u03bd\u03ae\u03bb\u03b9\u03ba\u03b7 \u03b6\u03c9\u03ae. \u0391\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b4\u03b5\u03bd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03b5\u03af \u03c3\u03b5 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03ae \u03c3\u03b5 \u03bd\u03b5\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b5\u03c2, \u03b1\u03bb\u03bb\u03ac \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ac \u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03ad\u03c3\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2. \u0397 \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03ae\u03c2 \u03bc\u03b5\u03c4\u03ac\u03b4\u03bf\u03c3\u03b7 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03ba\u03b1\u03bd\u03cc\u03bd\u03b1\u03c2. \u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ba\u03ac\u03c0\u03bf\u03b9\u03b1 <strong>\u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7<\/strong>, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03b4\u03b5\u03bd \u03ba\u03bb\u03b7\u03c1\u03bf\u03bd\u03bf\u03bc\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c0\u03bb\u03cc \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c8\u03b9\u03bc\u03bf \u03c4\u03c1\u03cc\u03c0\u03bf.<\/p>\n<p>\u039f\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b4\u03b5\u03bd \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03c3\u03bf\u03c5\u03bd \u03bc\u03af\u03b1 \u03bc\u03bf\u03bd\u03b1\u03b4\u03b9\u03ba\u03ae \u03b1\u03b9\u03c4\u03af\u03b1. \u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bc\u03b5 \u03cc\u03c4\u03b9 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 <strong>\u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03af \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2<\/strong>, <strong>\u03bf\u03c1\u03bc\u03bf\u03bd\u03b9\u03ba\u03bf\u03af \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03af<\/strong>, \u03c0\u03b5\u03c1\u03b9\u03b2\u03b1\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03ba\u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03c5\u03b1\u03bb\u03c9\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1. \u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c0\u03c1\u03ac\u03be\u03b7 \u03bf \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1 \u03b2\u03c1\u03bf\u03cd\u03bc\u03b5 \u00ab\u03c0\u03bf\u03b9\u03bf\u03c2 \u03ad\u03c6\u03c4\u03b1\u03b9\u03be\u03b5\u00bb, \u03b1\u03bb\u03bb\u03ac \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03c3\u03bf\u03c5\u03bc\u03b5 <strong>\u03c0\u03cc\u03c3\u03bf \u03b5\u03bd\u03b5\u03c1\u03b3\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2<\/strong>, <strong>\u03c0\u03bf\u03b9\u03b1 \u03cc\u03c1\u03b3\u03b1\u03bd\u03b1 \u03b1\u03c0\u03b5\u03b9\u03bb\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9<\/strong> \u03ba\u03b1\u03b9 <strong>\u03c4\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9<\/strong>.<\/p>\n<p>\u03a5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03bf\u03cd\u03bd \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf, \u03b1\u03bb\u03bb\u03ac \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c7\u03b5\u03b9\u03c1\u03bf\u03c4\u03b5\u03c1\u03b5\u03cd\u03c3\u03bf\u03c5\u03bd \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03c3\u03b5\u03b9\u03c2. \u039f \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf <strong>\u03ba\u03ac\u03c0\u03bd\u03b9\u03c3\u03bc\u03b1<\/strong>, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b5\u03c0\u03b9\u03b2\u03b1\u03c1\u03cd\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03b5\u03cd\u03b5\u03b9 \u03c4\u03bf Raynaud \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ac \u03c4\u03b7 \u03bc\u03b9\u03ba\u03c1\u03bf\u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae \u03b5\u03c6\u03b5\u03b4\u03c1\u03b5\u03af\u03b1. \u0393\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc \u03b7 \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae \u03ba\u03b1\u03c0\u03bd\u03af\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03ae \u03c5\u03b3\u03b5\u03af\u03b1\u03c2. \u0395\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 5 ==================== --><\/p>\n<section id=\"section-5\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">5<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03c1\u03ce\u03b9\u03bc\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03b3\u03bd\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd<\/span><\/h2>\n<p>\u03a4\u03bf \u03c0\u03c1\u03ce\u03c4\u03bf \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf \u03c0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03cc \u03c3\u03b7\u03bc\u03b5\u03af\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf <strong>\u03c6\u03b1\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf Raynaud<\/strong>: \u03c4\u03b1 \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1 \u03b1\u03bb\u03bb\u03ac\u03b6\u03bf\u03c5\u03bd \u03c7\u03c1\u03ce\u03bc\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03ba\u03c1\u03cd\u03bf \u03ae \u03c4\u03bf \u03c3\u03c4\u03c1\u03b5\u03c2, \u03b3\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bb\u03b5\u03c5\u03ba\u03ac, \u03bc\u03c0\u03bb\u03b5 \u03ae \u03b5\u03c1\u03c5\u03b8\u03c1\u03ac \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bc\u03bf\u03cd\u03b4\u03b9\u03b1\u03c3\u03bc\u03b1 \u03ae \u03c0\u03cc\u03bd\u03bf. \u0391\u03c0\u03cc \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c4\u03bf Raynaud \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1, \u03b1\u03bb\u03bb\u03ac \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03b4\u03c5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 <strong>\u03c0\u03c1\u03b7\u03c3\u03bc\u03ad\u03bd\u03b1 \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1<\/strong>, <strong>\u03c3\u03c6\u03af\u03be\u03b9\u03bc\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2<\/strong>, <strong>\u03b8\u03b5\u03c4\u03b9\u03ba\u03ac ANA<\/strong> \u03ae <strong>\u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c4\u03c1\u03b9\u03c7\u03bf\u03b5\u03b9\u03b4\u03bf\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7<\/strong>, \u03c4\u03cc\u03c4\u03b5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7.<\/p>\n<p>\u0386\u03bb\u03bb\u03bf \u03c0\u03c1\u03ce\u03b9\u03bc\u03bf \u03c3\u03b7\u03bc\u03ac\u03b4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 <strong>puffy fingers<\/strong>, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03c0\u03c1\u03b7\u03c3\u03bc\u03ad\u03bd\u03b1 \u03ae \u00ab\u03c6\u03bf\u03c5\u03c3\u03ba\u03c9\u03bc\u03ad\u03bd\u03b1\u00bb \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03c1\u03b3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c0\u03bf\u03ba\u03c4\u03bf\u03cd\u03bd \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2. \u03a0\u03bf\u03bb\u03bb\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03ac\u03c6\u03bf\u03c5\u03bd \u03c9\u03c2 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03bd\u03b1 \u03b2\u03b3\u03ac\u03bb\u03bf\u03c5\u03bd \u03b4\u03b1\u03c7\u03c4\u03c5\u03bb\u03af\u03b4\u03b9\u03b1 \u03ae \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03cc\u03c4\u03b9 \u03c4\u03b1 \u03c7\u03ad\u03c1\u03b9\u03b1 \u00ab\u03b4\u03b5\u03bd \u03bb\u03c5\u03b3\u03af\u03b6\u03bf\u03c5\u03bd \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac\u00bb. \u03a3\u03c5\u03c7\u03bd\u03ac \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd <strong>\u03ba\u03b1\u03bf\u03cd\u03c1\u03b5\u03c2<\/strong>, <strong>\u03b4\u03c5\u03c3\u03c6\u03b1\u03b3\u03af\u03b1<\/strong>, \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03c4\u03c1\u03bf\u03c6\u03ae\u03c2 \u03c0\u03bf\u03c5 \u00ab\u03ba\u03bf\u03bb\u03bb\u03ac\u03b5\u03b9\u00bb, \u03ae \u03b4\u03c5\u03c3\u03c6\u03bf\u03c1\u03af\u03b1 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b1 \u03b3\u03b5\u03cd\u03bc\u03b1\u03c4\u03b1.<\/p>\n<p>\u03a3\u03b7\u03bc\u03ac\u03b4\u03b9\u03b1 \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b9\u03bf \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 <strong>\u03bd\u03ad\u03b1 \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1<\/strong>, \u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03b1\u03bd\u03c4\u03bf\u03c7\u03ae\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b7\u03c6\u03cc\u03c1\u03b1 \u03ae \u03c3\u03c4\u03bf \u03c0\u03b5\u03c1\u03c0\u03ac\u03c4\u03b7\u03bc\u03b1, \u03bf <strong>\u03be\u03b7\u03c1\u03cc\u03c2 \u03b2\u03ae\u03c7\u03b1\u03c2<\/strong>, \u03c4\u03b1 <strong>\u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03b9\u03ba\u03ac \u03ad\u03bb\u03ba\u03b7<\/strong>, \u03b7 <strong>\u03b1\u03c0\u03cc\u03c4\u03bf\u03bc\u03b7 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2<\/strong>, \u03bf \u03ad\u03bd\u03c4\u03bf\u03bd\u03bf\u03c2 \u03c0\u03bf\u03bd\u03bf\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03b8\u03bf\u03bb\u03ae \u03cc\u03c1\u03b1\u03c3\u03b7. \u0395\u03b9\u03b4\u03b9\u03ba\u03ac \u03bf \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c3\u03ba\u03bb\u03b7\u03c1\u03bf\u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 <strong>\u03b1\u03b9\u03c6\u03bd\u03af\u03b4\u03b9\u03b1\u03c2 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7\u03c2<\/strong> \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b5\u03c0\u03b5\u03af\u03b3\u03bf\u03c5\u03c3\u03b1 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03b1\u03c0\u03bf\u03b4\u03b5\u03af\u03be\u03b5\u03c9\u03c2 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03b1\u03bd\u03c4\u03af\u03bf\u03c5.<\/p>\n<div style=\"background: #fff7ed; border-left: 4px solid #ea580c; border-radius: 10px; padding: 12px 14px; margin: 12px 0 16px;\"><strong>\u03a0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac:<\/strong> \u0391\u03bd \u03ad\u03c7\u03b5\u03c4\u03b5 <strong>Raynaud + \u03c3\u03c6\u03b9\u03c7\u03c4\u03ac \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1 + \u03ba\u03b1\u03bf\u03cd\u03c1\u03b5\u03c2\/\u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1<\/strong>, \u03bc\u03b7\u03bd \u03b1\u03c1\u03ba\u03b5\u03c3\u03c4\u03b5\u03af\u03c4\u03b5 \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ae \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7 \u03c4\u03cd\u03c0\u03bf\u03c5 \u00ab\u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c3\u03c4\u03c1\u03b5\u03c2\u00bb. \u0395\u03af\u03bd\u03b1\u03b9 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03cc\u03c2 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03be\u03af\u03b6\u03b5\u03b9 <strong>\u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf<\/strong>.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 6 ==================== --><\/p>\n<section id=\"section-6\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">6<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03c3\u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1, \u03c3\u03c4\u03b1 \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03b1\u03b3\u03b3\u03b5\u03af\u03b1<\/span><\/h2>\n<p>\u03a4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03c0\u03b9\u03bf \u03bf\u03c1\u03b1\u03c4\u03cc \u03ba\u03bf\u03bc\u03bc\u03ac\u03c4\u03b9 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03b1\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b2\u03bf\u03b7\u03b8\u03ac \u03bd\u03b1 \u03c4\u03b5\u03b8\u03b5\u03af \u03b7 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1. \u03a4\u03bf \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03cc \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 <strong>\u03c3\u03ba\u03bb\u03b7\u03c1\u03bf\u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03af\u03b1<\/strong>, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03c0\u03ac\u03c7\u03c5\u03bd\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c6\u03af\u03be\u03b9\u03bc\u03bf \u03c3\u03c4\u03b1 \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1. \u039c\u03b5 \u03c4\u03bf\u03bd \u03c7\u03c1\u03cc\u03bd\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03b5\u03cd\u03b5\u03b9 \u03b7 \u03c0\u03bb\u03ae\u03c1\u03b7\u03c2 \u03ba\u03ac\u03bc\u03c8\u03b7 \u03ae \u03ad\u03ba\u03c4\u03b1\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c7\u03b5\u03c1\u03b9\u03ce\u03bd, \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03bb\u03b5\u03c0\u03c4\u03ae \u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf \u03ac\u03bd\u03bf\u03b9\u03b3\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2.<\/p>\n<p>\u03a3\u03c4\u03bf \u03c0\u03c1\u03cc\u03c3\u03c9\u03c0\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03b5\u03af \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1 \u00ab\u03c4\u03c1\u03b1\u03b2\u03ac\u03b5\u03b9\u00bb, \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03bf \u03ac\u03bd\u03bf\u03b9\u03b3\u03bc\u03b1 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03b9\u03bf \u03bb\u03b5\u03af\u03b1, \u03b3\u03c5\u03b1\u03bb\u03b9\u03c3\u03c4\u03b5\u03c1\u03ae \u03cc\u03c8\u03b7. \u03a3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 <strong>\u03c4\u03b5\u03bb\u03b1\u03b3\u03b3\u03b5\u03b9\u03b5\u03ba\u03c4\u03b1\u03c3\u03af\u03b5\u03c2<\/strong>, \u03bc\u03b9\u03ba\u03c1\u03ad\u03c2 \u03ba\u03cc\u03ba\u03ba\u03b9\u03bd\u03b5\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b2\u03bb\u03ac\u03b2\u03b5\u03c2 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03b5 \u03c0\u03c1\u03cc\u03c3\u03c9\u03c0\u03bf \u03ba\u03b1\u03b9 \u03c7\u03ad\u03c1\u03b9\u03b1, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 <strong>\u03b1\u03c3\u03b2\u03ad\u03c3\u03c4\u03c9\u03c3\u03b7<\/strong> \u03ba\u03ac\u03c4\u03c9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1. \u038c\u03bb\u03b1 \u03b1\u03c5\u03c4\u03ac \u03b4\u03b5\u03bd \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03cc\u03bd\u03bf \u03b1\u03b9\u03c3\u03b8\u03b7\u03c4\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1. \u0394\u03b5\u03af\u03c7\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b2\u03bb\u03ac\u03b2\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1\u03c2 \u03b1\u03bd\u03b1\u03b4\u03cc\u03bc\u03b7\u03c3\u03b7\u03c2 \u03b9\u03c3\u03c4\u03ce\u03bd.<\/p>\n<p>\u0397 \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b5\u03be\u03af\u03c3\u03bf\u03c5 \u03b5\u03bd\u03bf\u03c7\u03bb\u03b7\u03c4\u03b9\u03ba\u03ae. \u03a4\u03bf <strong>Raynaud<\/strong> \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ae\u03c0\u03b9\u03bf \u03ad\u03c9\u03c2 \u03b5\u03be\u03bf\u03c5\u03b8\u03b5\u03bd\u03c9\u03c4\u03b9\u03ba\u03cc. \u03a3\u03b5 \u03c0\u03b9\u03bf \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03c3\u03c3\u03bf\u03bd\u03c4\u03b1\u03b9 <strong>\u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03b9\u03ba\u03ac \u03ad\u03bb\u03ba\u03b7<\/strong>, \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 \u03b9\u03c3\u03c7\u03b1\u03b9\u03bc\u03af\u03b1\u03c2, \u03b5\u03c0\u03b9\u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03cc\u03bd\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf\u03bd \u03cd\u03c0\u03bd\u03bf, \u03c4\u03b7\u03bd \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1. \u0397 \u03c3\u03c9\u03c3\u03c4\u03ae \u03c4\u03bf\u03c0\u03b9\u03ba\u03ae \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1, \u03b7 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c3\u03af\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03ba\u03c1\u03cd\u03bf \u03ba\u03b1\u03b9 \u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03b4\u03b9\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u00ab\u03b4\u03b5\u03c5\u03c4\u03b5\u03c1\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u00bb. \u0395\u03af\u03bd\u03b1\u03b9 \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03ac \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1\u03c2.<\/p>\n<p>\u03a3\u03c4\u03bf \u03b9\u03b1\u03c4\u03c1\u03b5\u03af\u03bf, \u03b7 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae\u03c2 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03bf\u03bd <strong>modified Rodnan skin score<\/strong>. \u03a0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c3\u03b5 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2. \u0394\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7, \u03b1\u03bb\u03bb\u03ac \u03c0\u03bf\u03bb\u03cd \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03bf \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03ba\u03b1\u03c4\u03b1\u03bb\u03ac\u03b2\u03bf\u03c5\u03bc\u03b5 \u03b1\u03bd \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae, \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ae \u03c0\u03c1\u03bf\u03bf\u03b4\u03b5\u03cd\u03b5\u03b9.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 7 ==================== --><\/p>\n<section id=\"section-7\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">7<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c0\u03bd\u03bf\u03ae: \u03b3\u03b9\u03b1\u03c4\u03af \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03cc\u03c3\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03bf\u03af<\/span><\/h2>\n<p>\u039f\u03b9 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03cc\u03c1\u03b3\u03b1\u03bd\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c3\u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1. \u039f\u03b9 \u03b4\u03cd\u03bf \u03b2\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 <strong>\u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 (ILD)<\/strong> \u03ba\u03b1\u03b9 \u03b7 <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7 (\u03a0\u0391\u03a5)<\/strong>. \u0394\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03af\u03b4\u03b9\u03bf \u03c0\u03c1\u03ac\u03b3\u03bc\u03b1, \u03b1\u03bd \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd.<\/p>\n<p>\u0397 <strong>ILD<\/strong> \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03b1\u03c1\u03ad\u03b3\u03c7\u03c5\u03bc\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03b9 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7 \u03ba\u03b1\u03b9 \u03b9\u03bd\u03c9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae. \u039f \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 <strong>\u03be\u03b7\u03c1\u03cc \u03b2\u03ae\u03c7\u03b1<\/strong>, <strong>\u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1<\/strong> \u03ae \u03b1\u03c0\u03bb\u03ce\u03c2 \u03bd\u03b1 \u03ba\u03bf\u03c5\u03c1\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c4\u03b9\u03c2 \u03c3\u03ba\u03ac\u03bb\u03b5\u03c2. \u039c\u03b5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c6\u03bf\u03c1\u03ad\u03c2 \u03b7 \u03c0\u03c4\u03ce\u03c3\u03b7 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03ce\u03c4\u03b1 \u03c3\u03c4\u03b9\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac \u03c3\u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1. \u0393\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03b5\u03af \u03bd\u03b1 \u03c1\u03c9\u03c4\u03ac\u03bc\u03b5 \u03bc\u03cc\u03bd\u03bf \u00ab\u03b1\u03bd\u03b1\u03c0\u03bd\u03ad\u03c9 \u03ba\u03b1\u03bb\u03ac\u00bb. \u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 <strong>\u03c3\u03c0\u03b9\u03c1\u03bf\u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7<\/strong>, <strong>DLCO<\/strong> \u03ba\u03b1\u03b9, \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7, <strong>HRCT<\/strong>.<\/p>\n<p>\u0397 <strong>\u03a0\u0391\u03a5<\/strong> \u03b1\u03c6\u03bf\u03c1\u03ac \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c4\u03b1 \u03b1\u03b3\u03b3\u03b5\u03af\u03b1 \u03c4\u03c9\u03bd \u03c0\u03bd\u03b5\u03c5\u03bc\u03cc\u03bd\u03c9\u03bd. \u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03ce\u03c3\u03b5\u03b9 <strong>\u03c0\u03c1\u03bf\u03bf\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7<\/strong>, <strong>\u03b6\u03ac\u03bb\u03b7<\/strong>, <strong>\u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03c4\u03bf\u03c7\u03ae<\/strong>, \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03bf\u03b9\u03b4\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03b1 \u03c0\u03cc\u03b4\u03b9\u03b1 \u03c3\u03b5 \u03c0\u03c1\u03bf\u03c7\u03c9\u03c1\u03b7\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2. \u03a3\u03c4\u03b1 \u03b1\u03c1\u03c7\u03b9\u03ba\u03ac \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cd\u03c0\u03bf\u03c5\u03bb\u03b7. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03bf\u03b9 \u03c3\u03cd\u03b3\u03c7\u03c1\u03bf\u03bd\u03b5\u03c2 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u03b4\u03af\u03bd\u03bf\u03c5\u03bd \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c4\u03bf <strong>\u03b5\u03c4\u03ae\u03c3\u03b9\u03bf screening<\/strong> \u03bc\u03b5 <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ad\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b5\u03c2<\/strong>, <strong>\u03b7\u03c7\u03bf\u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03b3\u03c1\u03ac\u03c6\u03b7\u03bc\u03b1<\/strong> \u03ba\u03b1\u03b9 <strong>NT-proBNP<\/strong>.<\/p>\n<p>\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1 \u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03b5\u03af \u03bd\u03b1 \u03c0\u03bf\u03cd\u03bc\u03b5 \u00ab\u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf\u00bb. \u03a0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b5\u03c5\u03ba\u03c1\u03b9\u03bd\u03b9\u03c3\u03c4\u03b5\u03af \u03b1\u03bd \u03c6\u03c4\u03b1\u03af\u03b5\u03b9 <strong>\u03af\u03bd\u03c9\u03c3\u03b7<\/strong>, <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7<\/strong>, <strong>\u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae<\/strong>, \u03b1\u03bd\u03b1\u03b9\u03bc\u03af\u03b1, \u03b1\u03c0\u03bf\u03c1\u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03b1\u03c0\u03cc \u03c0\u03b1\u03bb\u03b9\u03bd\u03b4\u03c1\u03cc\u03bc\u03b7\u03c3\u03b7 \u03ae \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd. \u0397 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03c4\u03cc\u03c3\u03bf \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c4\u03b1\u03c7\u03cd\u03c4\u03b7\u03c4\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03bf\u03c0\u03bf\u03af\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03ba\u03b9\u03bd\u03b7\u03b8\u03b5\u03af \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 8 ==================== --><\/p>\n<section id=\"section-8\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">8<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u039a\u03b1\u03c1\u03b4\u03b9\u03ac, \u03bd\u03b5\u03c6\u03c1\u03bf\u03af \u03ba\u03b1\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2<\/span><\/h2>\n<p>\u0397 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03c3\u03b9\u03c9\u03c0\u03b7\u03bb\u03ae \u03b1\u03c0\u03cc \u03cc\u03c3\u03bf \u03bd\u03bf\u03bc\u03af\u03b6\u03b5\u03b9 \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2. \u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd <strong>\u03b1\u03c1\u03c1\u03c5\u03b8\u03bc\u03af\u03b5\u03c2<\/strong>, \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03c0\u03b1\u03bb\u03bc\u03ce\u03bd, \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03c4\u03bf\u03c7\u03ae, \u03c0\u03b5\u03c1\u03b9\u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03ae \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03b4\u03b5\u03be\u03b9\u03ac\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac\u03c2, \u03b9\u03b4\u03af\u03c9\u03c2 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7. \u03a3\u03b5 \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b7 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b2\u03bb\u03ac\u03b2\u03b7 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c1\u03c7\u03b9\u03ba\u03ac \u03bc\u03b5 <strong>\u03c4\u03c1\u03bf\u03c0\u03bf\u03bd\u03af\u03bd\u03b7<\/strong>, <strong>NT-proBNP<\/strong>, <strong>\u0397\u039a\u0393<\/strong> \u03ae <strong>\u03c5\u03c0\u03ad\u03c1\u03b7\u03c7\u03bf \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac\u03c2<\/strong>, \u03c0\u03c1\u03b9\u03bd \u03b1\u03ba\u03cc\u03bc\u03b7 \u03b5\u03be\u03b5\u03bb\u03b9\u03c7\u03b8\u03b5\u03af \u03c3\u03b5 \u03c0\u03b9\u03bf \u03ba\u03b1\u03b8\u03b1\u03c1\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1.<\/p>\n<p>\u039f\u03b9 <strong>\u03bd\u03b5\u03c6\u03c1\u03bf\u03af<\/strong> \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae, \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03bc\u03bf\u03c1\u03c6\u03ae \u03ba\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03bd\u03cc\u03c3\u03bf\u03c5. \u0397 \u03c0\u03b9\u03bf \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 <strong>\u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03ba\u03c1\u03af\u03c3\u03b7 \u03c3\u03ba\u03bb\u03b7\u03c1\u03bf\u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2<\/strong>. \u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 <strong>\u03b1\u03c0\u03cc\u03c4\u03bf\u03bc\u03b7 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7<\/strong>, <strong>\u03c4\u03b1\u03c7\u03b5\u03af\u03b1 \u03ac\u03bd\u03bf\u03b4\u03bf \u03ba\u03c1\u03b5\u03b1\u03c4\u03b9\u03bd\u03af\u03bd\u03b7\u03c2<\/strong>, \u03ba\u03b5\u03c6\u03b1\u03bb\u03b1\u03bb\u03b3\u03af\u03b1, \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2 \u03cc\u03c1\u03b1\u03c3\u03b7\u03c2, \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1 \u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03c0\u03b1\u03b8\u03b7\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7\u03c2. \u0395\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03b5\u03af\u03b3\u03bf\u03c5\u03c3\u03b1 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 <strong>\u03ac\u03bc\u03b5\u03c3\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7<\/strong>.<\/p>\n<p>\u0393\u03b9\u03b1 \u03c4\u03bf\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae, \u03c4\u03bf \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc \u03bc\u03ae\u03bd\u03c5\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b1\u03c6\u03ad\u03c2: \u03c3\u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b4\u03b5\u03bd \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03bc\u03b5 \u03bc\u03cc\u03bd\u03bf \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2. \u039c\u03b5\u03c4\u03c1\u03ac\u03bc\u03b5 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac <strong>\u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c0\u03af\u03b5\u03c3\u03b7<\/strong>, \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5\u03bc\u03b5 <strong>\u03ba\u03c1\u03b5\u03b1\u03c4\u03b9\u03bd\u03af\u03bd\u03b7<\/strong>, <strong>\u03bf\u03cd\u03c1\u03b1<\/strong>, \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03bf\u03cd\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03bc\u03b5\u03bb\u03bf\u03cd\u03bc\u03b5 \u03bd\u03ad\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03cc\u03c0\u03c9\u03c2 \u03c0\u03bf\u03bd\u03bf\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf, \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03c0\u03b1\u03bb\u03bc\u03ce\u03bd \u03ae \u03b1\u03bd\u03b5\u03be\u03ae\u03b3\u03b7\u03c4\u03b7 \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7\u03c2.<\/p>\n<div style=\"background: #fef2f2; border: 1px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0 16px;\"><strong>\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc:<\/strong> \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1, <strong>\u03be\u03b1\u03c6\u03bd\u03b9\u03ba\u03ae \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2<\/strong>, <strong>\u03c0\u03bf\u03bd\u03bf\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf\u03c2<\/strong>, <strong>\u03b8\u03bf\u03bb\u03ae \u03cc\u03c1\u03b1\u03c3\u03b7<\/strong> \u03ae <strong>\u03b1\u03c0\u03cc\u03c4\u03bf\u03bc\u03b7 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2<\/strong> \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 <strong>\u03ac\u03bc\u03b5\u03c3\u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7<\/strong>. \u0394\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03cd\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5\u03bc\u03b5 \u00ab\u03bd\u03b1 \u03c0\u03b5\u03c1\u03ac\u03c3\u03b5\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5\u00bb.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 9 ==================== --><\/p>\n<section id=\"section-9\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">9<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u039f\u03b9\u03c3\u03bf\u03c6\u03ac\u03b3\u03bf\u03c2, \u03c3\u03c4\u03bf\u03bc\u03ac\u03c7\u03b9 \u03ba\u03b1\u03b9 \u03ad\u03bd\u03c4\u03b5\u03c1\u03bf<\/span><\/h2>\n<p>\u03a4\u03bf \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c0\u03b9\u03bf \u03c3\u03c5\u03c7\u03bd\u03ac \u03b5\u03c0\u03b7\u03c1\u03b5\u03b1\u03b6\u03cc\u03bc\u03b5\u03bd\u03b1 \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1. \u0397 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03c3\u03c5\u03c7\u03bd\u03ac \u03be\u03b5\u03ba\u03b9\u03bd\u03ac \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd <strong>\u03bf\u03b9\u03c3\u03bf\u03c6\u03ac\u03b3\u03bf<\/strong>. \u0395\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 <strong>\u03ba\u03b1\u03bf\u03cd\u03c1\u03b5\u03c2<\/strong>, <strong>\u03c0\u03b1\u03bb\u03b9\u03bd\u03b4\u03c1\u03cc\u03bc\u03b7\u03c3\u03b7<\/strong>, \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03cc\u03c4\u03b9 \u03b7 \u03c4\u03c1\u03bf\u03c6\u03ae \u00ab\u03ba\u03bf\u03bb\u03bb\u03ac\u03b5\u03b9\u00bb, \u03b2\u03c1\u03b1\u03c7\u03bd\u03ac\u03b4\u03b1 \u03ae \u03b2\u03ae\u03c7\u03b1\u03c2 \u03c4\u03b7 \u03bd\u03cd\u03c7\u03c4\u03b1. \u03a0\u03bf\u03bb\u03bb\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c4\u03bf \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd \u03ad\u03bd\u03b1 \u03b1\u03c0\u03bb\u03cc \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c3\u03cd\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1, \u03b1\u03bb\u03bb\u03ac \u03c3\u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b7 \u03c0\u03b1\u03bb\u03b9\u03bd\u03b4\u03c1\u03cc\u03bc\u03b7\u03c3\u03b7 \u03b1\u03be\u03af\u03b6\u03b5\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae, \u03b3\u03b9\u03b1\u03c4\u03af \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b6\u03c9\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03af\u03bf\u03c4\u03b5 \u03b5\u03c0\u03b9\u03b2\u03b1\u03c1\u03cd\u03bd\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03cc.<\/p>\n<p>\u03a0\u03b9\u03bf \u03c7\u03b1\u03bc\u03b7\u03bb\u03ac, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd <strong>\u03c6\u03bf\u03cd\u03c3\u03ba\u03c9\u03bc\u03b1<\/strong>, <strong>\u03b5\u03bd\u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03b4\u03b9\u03ac\u03c1\u03c1\u03bf\u03b9\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03c5\u03c3\u03ba\u03bf\u03b9\u03bb\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2<\/strong>, \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03b1\u03c4\u03b5\u03bb\u03bf\u03cd\u03c2 \u03c0\u03ad\u03c8\u03b7\u03c2, \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2 \u03ae \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 <strong>\u03b4\u03c5\u03c3\u03b1\u03c0\u03bf\u03c1\u03c1\u03cc\u03c6\u03b7\u03c3\u03b7\u03c2<\/strong>. \u0388\u03bd\u03b1 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 <strong>\u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c5\u03c0\u03b5\u03c1\u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03bb\u03b5\u03c0\u03c4\u03bf\u03cd \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5 (SIBO)<\/strong>, \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03af\u03bd\u03b5\u03b9 \u03ad\u03bd\u03c4\u03bf\u03bd\u03bf \u03bc\u03b5\u03c4\u03b5\u03c9\u03c1\u03b9\u03c3\u03bc\u03cc, \u03c5\u03c0\u03bf\u03b8\u03c1\u03b5\u03c8\u03af\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b1\u03c0\u03bf\u03c1\u03c1\u03cc\u03c6\u03b7\u03c3\u03b7 \u03b8\u03c1\u03b5\u03c0\u03c4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c5\u03c3\u03b9\u03ce\u03bd.<\/p>\n<p>\u0397 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03c3\u03c5\u03bd\u03b4\u03c5\u03ac\u03b6\u03b5\u03b9 <strong>\u03bc\u03ad\u03c4\u03c1\u03b1 \u03c4\u03c1\u03cc\u03c0\u03bf\u03c5 \u03b6\u03c9\u03ae\u03c2<\/strong>, \u03cc\u03c0\u03c9\u03c2 \u03bc\u03b9\u03ba\u03c1\u03ac \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b3\u03b5\u03cd\u03bc\u03b1\u03c4\u03b1, \u03b1\u03c0\u03bf\u03c6\u03c5\u03b3\u03ae \u03b2\u03b1\u03c1\u03b9\u03bf\u03cd \u03b2\u03c1\u03b1\u03b4\u03b9\u03bd\u03bf\u03cd, \u03b1\u03bd\u03cd\u03c8\u03c9\u03c3\u03b7 \u03ba\u03b5\u03c6\u03b1\u03bb\u03ae\u03c2 \u03ba\u03c1\u03b5\u03b2\u03b1\u03c4\u03b9\u03bf\u03cd, \u03bc\u03b5 <strong>\u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1<\/strong> \u03cc\u03c0\u03c9\u03c2 <strong>PPI<\/strong>, \u03ba\u03b1\u03c4\u03ac \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 <strong>\u03c0\u03c1\u03bf\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac<\/strong> \u03ba\u03b1\u03b9, \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 SIBO, \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b7 <strong>\u03b1\u03bd\u03c4\u03b9\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae<\/strong>. \u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2 \u03ae \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03c5\u03c0\u03bf\u03b8\u03c1\u03b5\u03c8\u03af\u03b1\u03c2, \u03b7 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03b5\u03c1\u03b5\u03af.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 10 ==================== --><\/p>\n<section id=\"section-10\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">10<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03ce\u03c2 \u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/span><\/h2>\n<p>\u0397 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b4\u03b5\u03bd \u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03bc\u03cc\u03bd\u03bf \u03c4\u03b5\u03c3\u03c4. \u039f \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03c3\u03c5\u03bd\u03b4\u03c5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf <strong>\u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc<\/strong>, \u03c4\u03b7\u03bd <strong>\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/strong>, \u03c4\u03b9\u03c2 <strong>\u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2\/\u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2<\/strong>, \u03c4\u03b7\u03bd <strong>\u03c4\u03c1\u03b9\u03c7\u03bf\u03b5\u03b9\u03b4\u03bf\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7<\/strong> \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd. \u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7, \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03bc\u03c0\u03b1\u03af\u03bd\u03b5\u03b9 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03b9 Raynaud, \u03c0\u03c1\u03b7\u03c3\u03bc\u03ad\u03bd\u03b1 \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1, \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2, \u03c0\u03b1\u03bb\u03b9\u03bd\u03b4\u03c1\u03cc\u03bc\u03b7\u03c3\u03b7 \u03ae \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf\u03c2 \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03c5\u03c0\u03bf\u03c8\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03b5\u03c4\u03b9\u03ba\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1.<\/p>\n<p>\u03a4\u03b1 <strong>ACR\/EULAR \u03ba\u03c1\u03b9\u03c4\u03ae\u03c1\u03b9\u03b1 \u03c4\u03b1\u03be\u03b9\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7\u03c2<\/strong> \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd <strong>\u03b2\u03b1\u03b8\u03bc\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1<\/strong>. \u0391\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b5\u03ba\u03c4\u03b5\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03ac \u03c0\u03ad\u03c1\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03ba\u03b1\u03c1\u03c0\u03b9\u03bf\u03c6\u03b1\u03bb\u03b1\u03b3\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c1\u03b8\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2, \u03b1\u03c5\u03c4\u03cc \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03b1\u03c1\u03ba\u03b5\u03af \u03b3\u03b9\u03b1 \u03c4\u03b1\u03be\u03b9\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7. \u0394\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac, \u03b1\u03b8\u03c1\u03bf\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03cc\u03c0\u03c9\u03c2 <strong>puffy fingers<\/strong>, <strong>\u03c3\u03ba\u03bb\u03b7\u03c1\u03bf\u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03af\u03b1<\/strong>, <strong>\u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03b9\u03ba\u03ac \u03ad\u03bb\u03ba\u03b7 \u03ae \u03bf\u03c5\u03bb\u03ad\u03c2<\/strong>, <strong>\u03c4\u03b5\u03bb\u03b1\u03b3\u03b3\u03b5\u03b9\u03b5\u03ba\u03c4\u03b1\u03c3\u03af\u03b5\u03c2<\/strong>, <strong>\u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03c4\u03c1\u03b9\u03c7\u03bf\u03b5\u03b9\u03b4\u03ae \u03bd\u03c5\u03c7\u03b9\u03ce\u03bd<\/strong>, <strong>Raynaud<\/strong>, <strong>ILD\/PAH<\/strong> \u03ba\u03b1\u03b9 <strong>\u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong>.<\/p>\n<p>\u03a0\u03bf\u03bb\u03cd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc: \u03c4\u03b1 \u03c4\u03b1\u03be\u03b9\u03bd\u03bf\u03bc\u03b9\u03ba\u03ac \u03ba\u03c1\u03b9\u03c4\u03ae\u03c1\u03b9\u03b1 \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03ba\u03c1\u03af\u03c3\u03b7. \u0388\u03bd\u03b1\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 <strong>\u03c0\u03bf\u03bb\u03cd \u03c0\u03c1\u03ce\u03b9\u03bc\u03bf \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf<\/strong> \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03bc\u03b7\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c3\u03c5\u03b3\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03c3\u03b5\u03b9 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1, \u03b1\u03bb\u03bb\u03ac \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ae\u03b4\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7, \u03b3\u03b9\u03b1\u03c4\u03af \u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03b1\u03c1\u03ba\u03c4\u03cc\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 10px 0;\">\u2194\ufe0f \u03a3\u03cd\u03c1\u03b5\u03c4\u03b5 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03c4\u03ae\u03bb\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03af\u03bd\u03b1\u03ba\u03b1<\/div>\n<div style=\"overflow-x: auto;\">\n<table style=\"width: 100%; border-collapse: collapse; min-width: 720px;\">\n<thead>\n<tr>\n<th style=\"text-align: left; border-bottom: 2px solid #e5e7eb; padding: 8px;\">\u0395\u03cd\u03c1\u03b7\u03bc\u03b1<\/th>\n<th style=\"text-align: left; border-bottom: 2px solid #e5e7eb; padding: 8px;\">\u0393\u03b9\u03b1\u03c4\u03af \u03bc\u03b5\u03c4\u03c1\u03ac\u03b5\u03b9<\/th>\n<th style=\"text-align: left; border-bottom: 2px solid #e5e7eb; padding: 8px;\">\u03a4\u03b9 \u03c5\u03c0\u03bf\u03c8\u03b9\u03ac\u03b6\u03b5\u03b9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">Raynaud<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u03a3\u03c5\u03c7\u03bd\u03cc \u03c0\u03c1\u03ce\u03b9\u03bc\u03bf \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03c3\u03cd\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u03a0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b1\u03c1\u03c7\u03cc\u03bc\u03b5\u03bd\u03b7 \u03c3\u03c5\u03bd\u03b4\u03b5\u03c4\u03b9\u03ba\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03b4\u03c5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">Puffy fingers \/ \u03c3\u03ba\u03bb\u03b7\u03c1\u03bf\u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03af\u03b1<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u0394\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u0395\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1\u03c2 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7\u03c2<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u03a4\u03c1\u03b9\u03c7\u03bf\u03b5\u03b9\u03b4\u03bf\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7 \u03bd\u03c5\u03c7\u03b9\u03ce\u03bd<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u0395\u03bb\u03ad\u03b3\u03c7\u03b5\u03b9 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03b2\u03bb\u03ac\u03b2\u03b7<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u03a3\u03ba\u03bb\u03b7\u03c1\u03bf\u03b4\u03b5\u03c1\u03bc\u03b9\u03ba\u03cc pattern \u03bc\u03b9\u03ba\u03c1\u03bf\u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03af\u03b1\u03c2<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">ANA \/ \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u039f\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03b3\u03c1\u03b1\u03c6\u03ae \u03bd\u03cc\u03c3\u03bf\u03c5<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u03a4\u03cd\u03c0\u03bf\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">HRCT \/ PFTs \/ DLCO<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u0388\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae\u03c2<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">ILD \u03ae \u03cd\u03c0\u03bf\u03c0\u03c4\u03b7 \u03a0\u0391\u03a5<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px;\">\u0397\u03c7\u03bf\u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03b3\u03c1\u03ac\u03c6\u03b7\u03bc\u03b1 \/ NT-proBNP<\/td>\n<td style=\"padding: 8px;\">\u039a\u03b1\u03c1\u03b4\u03b9\u03bf\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2<\/td>\n<td style=\"padding: 8px;\">\u03a0\u0391\u03a5 \u03ae \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/section>\n<p><!-- ==================== SECTION 11 ==================== --><\/p>\n<section id=\"section-11\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">11<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2<\/span><\/h2>\n<p>\u039f\u03b9 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b4\u03b5\u03bd \u00ab\u03bc\u03b5\u03c4\u03c1\u03bf\u03cd\u03bd\u00bb \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03b5\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03c4\u03b7 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5, \u03b1\u03bb\u03bb\u03ac \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5. \u03a4\u03bf \u03c0\u03c1\u03ce\u03c4\u03bf \u03b2\u03ae\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c4\u03b1 <strong>ANA<\/strong>. \u03a3\u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03c3\u03c5\u03c7\u03bd\u03ac \u03b8\u03b5\u03c4\u03b9\u03ba\u03ac, \u03b1\u03bb\u03bb\u03ac \u03c4\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b1\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03ac\u00b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03b9 <strong>\u03c0\u03bf\u03b9\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf pattern<\/strong> \u03ba\u03b1\u03b9 <strong>\u03c0\u03bf\u03b9\u03bf \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1<\/strong> \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b5\u03c0\u03cc\u03bc\u03b5\u03bd\u03bf \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf.<\/p>\n<p>\u03a4\u03b1 \u03c4\u03c1\u03af\u03b1 \u03c0\u03b9\u03bf \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ac SSc-related \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 <strong>anti-centromere<\/strong>, <strong>anti\u2013topoisomerase I \/ anti\u2013Scl-70<\/strong> \u03ba\u03b1\u03b9 <strong>anti\u2013RNA polymerase III<\/strong>. \u03a3\u03b5 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2, \u03c4\u03b1 <strong>anti-centromere<\/strong> \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5 <strong>\u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03bc\u03bf\u03c1\u03c6\u03ae<\/strong> \u03ba\u03b1\u03b9 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b3\u03b9\u03b1 <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7<\/strong>. \u03a4\u03b1 <strong>anti\u2013Scl-70<\/strong> \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5 <strong>\u03b4\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf<\/strong> \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 <strong>\u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7\u03c2 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1\u03c2<\/strong>. \u03a4\u03b1 <strong>anti\u2013RNA polymerase III<\/strong> \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5 <strong>\u03b4\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03bd\u03cc\u03c3\u03bf<\/strong> \u03ba\u03b1\u03b9 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03b5\u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03c3\u03b7 \u03b3\u03b9\u03b1 <strong>\u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03ba\u03c1\u03af\u03c3\u03b7<\/strong>.<\/p>\n<p>\u03a0\u03ad\u03c1\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1, \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 <strong>\u03b3\u03b5\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2<\/strong>, <strong>\u03a4\u039a\u0395\/CRP<\/strong>, <strong>\u03bf\u03c5\u03c1\u03af\u03b1\u03c2\/\u03ba\u03c1\u03b5\u03b1\u03c4\u03b9\u03bd\u03af\u03bd\u03b7\u03c2<\/strong>, <strong>\u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bd\u03b6\u03cd\u03bc\u03c9\u03bd<\/strong>, <strong>CPK<\/strong> \u03c3\u03b5 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae\u03c2, <strong>\u03b3\u03b5\u03bd\u03b9\u03ba\u03ae\u03c2 \u03bf\u03cd\u03c1\u03c9\u03bd<\/strong> \u03ba\u03b1\u03b9, \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9, <strong>NT-proBNP<\/strong> \u03ae <strong>\u03c4\u03c1\u03bf\u03c0\u03bf\u03bd\u03af\u03bd\u03b7\u03c2<\/strong>. \u0391\u03c5\u03c4\u03ad\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u00ab\u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2\u00bb \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b2\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03c5\u03b8\u03b5\u03af \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b1 \u03b1\u03bd \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf \u03cc\u03c1\u03b3\u03b1\u03bd\u03bf \u03b1\u03c1\u03c7\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03b9\u03ad\u03b6\u03b5\u03c4\u03b1\u03b9.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 10px 0;\">\u2194\ufe0f \u03a3\u03cd\u03c1\u03b5\u03c4\u03b5 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03c4\u03ae\u03bb\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03af\u03bd\u03b1\u03ba\u03b1<\/div>\n<div style=\"overflow-x: auto;\">\n<table style=\"width: 100%; border-collapse: collapse; min-width: 760px;\">\n<thead>\n<tr>\n<th style=\"text-align: left; border-bottom: 2px solid #e5e7eb; padding: 8px;\">\u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/th>\n<th style=\"text-align: left; border-bottom: 2px solid #e5e7eb; padding: 8px;\">\u03a4\u03b9 \u03bc\u03b1\u03c2 \u03bb\u03ad\u03b5\u03b9<\/th>\n<th style=\"text-align: left; border-bottom: 2px solid #e5e7eb; padding: 8px;\">\u03a3\u03c5\u03bd\u03b7\u03b8\u03ad\u03c3\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">ANA<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u0393\u03b5\u03bd\u03b9\u03ba\u03ae \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03bf\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03be\u03b5\u03b9\u03b4\u03af\u03ba\u03b5\u03c5\u03c3\u03b7 \u03bc\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">Anti-centromere<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u03a3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03bc\u03bf\u03c1\u03c6\u03ae<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u0388\u03bc\u03c6\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 screening \u03a0\u0391\u03a5<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">Anti\u2013Scl-70<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u03a3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5 \u03b4\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03bc\u03bf\u03c1\u03c6\u03ae<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u039c\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b5\u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03af\u03bd\u03c9\u03c3\u03b7<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">Anti\u2013RNA polymerase III<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u03a3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03bd\u03cc\u03c3\u03bf<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u03a3\u03c4\u03b5\u03bd\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">CRP \/ \u03a4\u039a\u0395<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u0393\u03b5\u03bd\u03b9\u03ba\u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1<\/td>\n<td style=\"padding: 8px; border-bottom: 1px solid #f1f5f9;\">\u0394\u03b5\u03bd \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03ce\u03bd\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03b5\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px;\">\u039a\u03c1\u03b5\u03b1\u03c4\u03b9\u03bd\u03af\u03bd\u03b7 \/ \u03b3\u03b5\u03bd\u03b9\u03ba\u03ae \u03bf\u03cd\u03c1\u03c9\u03bd<\/td>\n<td style=\"padding: 8px;\">\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03bd\u03b5\u03c6\u03c1\u03ce\u03bd<\/td>\n<td style=\"padding: 8px;\">\u03a7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ce\u03bd<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/section>\n<p><!-- ==================== SECTION 12 ==================== --><\/p>\n<section id=\"section-12\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">12<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0391\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd<\/span><\/h2>\n<p>\u0397 \u03c3\u03cd\u03b3\u03c7\u03c1\u03bf\u03bd\u03b7 \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1 \u03c3\u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b9\u03b4\u03ad\u03b1 \u03cc\u03c4\u03b9 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c8\u03ac\u03c7\u03bd\u03bf\u03c5\u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03b2\u03bf\u03bb\u03ae \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd <strong>\u03bd\u03c9\u03c1\u03af\u03c2<\/strong>, \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03cc\u03c4\u03b1\u03bd \u03b7 \u03b2\u03bb\u03ac\u03b2\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03b3\u03af\u03bd\u03b5\u03b9 \u03c0\u03c1\u03bf\u03c6\u03b1\u03bd\u03ae\u03c2. \u0393\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc \u03bf \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b7\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03b1.<\/p>\n<p>\u0393\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 <strong>\u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2<\/strong>, \u03b2\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ad\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b5\u03c2<\/strong> \u03bc\u03b5 <strong>FVC<\/strong> \u03ba\u03b1\u03b9 <strong>DLCO<\/strong>. \u0391\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ae \u03cd\u03c0\u03bf\u03c0\u03c4\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1, \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 <strong>HRCT<\/strong>. \u0393\u03b9\u03b1 \u03c4\u03b7\u03bd <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7<\/strong>, \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 <strong>\u03c5\u03c0\u03ad\u03c1\u03b7\u03c7\u03bf\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac\u03c2<\/strong>, <strong>NT-proBNP<\/strong> \u03ba\u03b1\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2, \u03b5\u03bd\u03ce \u03c3\u03b5 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af <strong>\u03b4\u03b5\u03be\u03b9\u03cc\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03cc\u03c2 \u03ba\u03b1\u03b8\u03b5\u03c4\u03b7\u03c1\u03b9\u03b1\u03c3\u03bc\u03cc\u03c2<\/strong>.<\/p>\n<p>\u0393\u03b9\u03b1 \u03c4\u03b7\u03bd <strong>\u03ba\u03b1\u03c1\u03b4\u03b9\u03ac<\/strong>, \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 <strong>\u0397\u039a\u0393<\/strong>, <strong>\u03b7\u03c7\u03bf\u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03b3\u03c1\u03ac\u03c6\u03b7\u03bc\u03b1<\/strong>, \u03ba\u03b1\u03c4\u03ac \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 <strong>\u03c4\u03c1\u03bf\u03c0\u03bf\u03bd\u03af\u03bd\u03b7<\/strong>, <strong>NT-proBNP<\/strong> \u03ba\u03b1\u03b9, \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7, <strong>\u03bc\u03b1\u03b3\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac\u03c2<\/strong>. \u0393\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 <strong>\u03bd\u03b5\u03c6\u03c1\u03bf\u03cd\u03c2<\/strong>, \u03b2\u03b1\u03c3\u03b9\u03ba\u03ac \u03b1\u03bb\u03bb\u03ac \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b1 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03b7 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c0\u03af\u03b5\u03c3\u03b7<\/strong>, \u03b7 <strong>\u03ba\u03c1\u03b5\u03b1\u03c4\u03b9\u03bd\u03af\u03bd\u03b7<\/strong> \u03ba\u03b1\u03b9 \u03b7 <strong>\u03b3\u03b5\u03bd\u03b9\u03ba\u03ae \u03bf\u03cd\u03c1\u03c9\u03bd<\/strong>. \u0393\u03b9\u03b1 \u03c4\u03bf <strong>\u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc<\/strong>, \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03b5\u03bd\u03b4\u03bf\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7, pH\u03bc\u03b5\u03c4\u03c1\u03af\u03b1 \u03ae \u03bc\u03b1\u03bd\u03bf\u03bc\u03b5\u03c4\u03c1\u03af\u03b1.<\/p>\n<p>\u03a3\u03b5 \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03cc \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf, \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03b4\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03bc\u03bd\u03b7\u03bc\u03bf\u03bd\u03b5\u03cd\u03c3\u03b5\u03b9 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03bf\u03bd\u03cc\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd. \u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af <strong>\u03c0\u03c1\u03cc\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1<\/strong> \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u00ab\u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03cc\u03c4\u03b1\u03bd \u03c0\u03bf\u03bd\u03ac\u03c9\u00bb. \u0397 \u03c0\u03c1\u03bf\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 13 ==================== --><\/p>\n<section id=\"section-13\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">13<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7<\/span><\/h2>\n<p>\u039f\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c1\u03c9\u03c4\u03bf\u03cd\u03bd: \u00ab\u0391\u03bd \u03b2\u03b3\u03b5\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti\u2013Scl-70, \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ad\u03c7\u03c9 \u03b2\u03b1\u03c1\u03b9\u03ac \u03bd\u03cc\u03c3\u03bf;\u00bb \u03ae \u00ab\u0391\u03bd \u03b7 DLCO \u03c0\u03ad\u03c3\u03b5\u03b9, \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03ad\u03c2 \u03bc\u03bf\u03c5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c7\u03b1\u03bb\u03ac\u03c3\u03b5\u03b9;\u00bb. \u0397 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 <strong>\u03c3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong>, \u03c4\u03b7\u03bd <strong>\u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/strong> \u03ba\u03b1\u03b9 \u03c4\u03bf <strong>\u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc<\/strong>. \u0388\u03bd\u03b1 \u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7. \u039c\u03b9\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03bb\u03b7 \u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1.<\/p>\n<p>\u0393\u03b9\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03b5\u03b9\u03b3\u03bc\u03b1, \u03ad\u03bd\u03b1 <strong>\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti-centromere<\/strong> \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7\u03c2 \u03bc\u03bf\u03c1\u03c6\u03ae\u03c2, \u03b1\u03bb\u03bb\u03ac \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03bb\u03ac \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c4\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc screening. \u0388\u03bd\u03b1 <strong>\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti\u2013Scl-70<\/strong> \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03b3\u03b9\u03b1 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae, \u03b1\u03bb\u03bb\u03ac \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b4\u03bf\u03cd\u03bc\u03b5 <strong>HRCT<\/strong>, <strong>\u03c3\u03c0\u03b9\u03c1\u03bf\u03bc\u03b5\u03c4\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2<\/strong> \u03ba\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1. \u0388\u03bd\u03b1 <strong>anti\u2013RNA polymerase III<\/strong> \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03bf\u03c0\u03c9\u03c3\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03b8\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b5\u03af \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03ba\u03c1\u03af\u03c3\u03b7, \u03b1\u03bb\u03bb\u03ac \u03cc\u03c4\u03b9 \u03b7 \u03b5\u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03c3\u03b7 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7.<\/p>\n<p>\u03a4\u03bf \u03af\u03b4\u03b9\u03bf \u03b9\u03c3\u03c7\u03cd\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2. \u039c\u03b9\u03b1 \u03c0\u03c4\u03ce\u03c3\u03b7 \u03c4\u03b7\u03c2 <strong>DLCO<\/strong> \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 <strong>\u03a0\u0391\u03a5<\/strong>, <strong>ILD<\/strong> \u03ae \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2. \u0388\u03bd\u03b1 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf <strong>NT-proBNP<\/strong> \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b1\u03c2 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03c0\u03b9\u03bf \u03c0\u03c1\u03bf\u03c3\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc \u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03ba\u03ac\u03bd\u03b5\u03b9 \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \u0391\u03c5\u03c4\u03cc\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03bf \u03bb\u03cc\u03b3\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03b7 <strong>\u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc<\/strong> \u03ad\u03c7\u03b5\u03b9 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1: \u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03b5\u03af \u03bd\u03b1 \u03b4\u03bf\u03cd\u03bc\u03b5 \u03b1\u03bd \u03ad\u03bd\u03b1 \u03bd\u03bf\u03cd\u03bc\u03b5\u03c1\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u00ab\u03ba\u03cc\u03ba\u03ba\u03b9\u03bd\u03bf\u00bb \u03ae \u00ab\u03c0\u03c1\u03ac\u03c3\u03b9\u03bd\u03bf\u00bb.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 14 ==================== --><\/p>\n<section id=\"section-14\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">14<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0392\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c1\u03c7\u03ad\u03c2<\/span><\/h2>\n<p>\u0394\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03af\u03b1 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c0\u03bf\u03c5 \u00ab\u03c3\u03b2\u03ae\u03bd\u03b5\u03b9\u00bb \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf \u03c3\u03b5 \u03cc\u03bb\u03bf\u03c5\u03c2. \u0397 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c3\u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b7<\/strong>. \u0386\u03bb\u03bb\u03bf \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03cd\u03bf\u03c5\u03bc\u03b5 \u03cc\u03c4\u03b1\u03bd \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03b5\u03af \u03c4\u03bf <strong>Raynaud<\/strong>, \u03ac\u03bb\u03bb\u03bf \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 <strong>ILD<\/strong>, \u03ac\u03bb\u03bb\u03bf \u03cc\u03c4\u03b1\u03bd \u03b7 \u03ba\u03cd\u03c1\u03b9\u03b1 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf <strong>\u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc<\/strong> \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03bf \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd <strong>\u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03b9\u03ba\u03ac \u03ad\u03bb\u03ba\u03b7<\/strong> \u03ae \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae.<\/p>\n<p>\u03a3\u03b5 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2, \u03c4\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c0\u03bb\u03ac\u03bd\u03bf \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c4\u03ad\u03c3\u03c3\u03b5\u03c1\u03b9\u03c2 \u03ac\u03be\u03bf\u03bd\u03b5\u03c2. \u03a0\u03c1\u03ce\u03c4\u03bf\u03bd, <strong>\u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c4\u03b7\u03c2 \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5<\/strong>. \u0394\u03b5\u03cd\u03c4\u03b5\u03c1\u03bf\u03bd, <strong>\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03bf\u03c5\u03c2\/\u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2<\/strong> \u03cc\u03c4\u03b1\u03bd \u03b1\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf. \u03a4\u03c1\u03af\u03c4\u03bf\u03bd, <strong>\u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03ae \u03b5\u03c0\u03b9\u03b2\u03c1\u03ac\u03b4\u03c5\u03bd\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03af\u03bd\u03c9\u03c3\u03b7\u03c2<\/strong> \u03c3\u03b5 \u03b4\u03ad\u03c1\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2. \u03a4\u03ad\u03c4\u03b1\u03c1\u03c4\u03bf\u03bd, <strong>\u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7<\/strong> \u03b3\u03b9\u03b1 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b6\u03c9\u03ae\u03c2, \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae, \u03c0\u03cc\u03bd\u03bf, \u03b4\u03ad\u03c1\u03bc\u03b1, \u03cd\u03c0\u03bd\u03bf \u03ba\u03b1\u03b9 \u03c8\u03c5\u03c7\u03bf\u03bb\u03bf\u03b3\u03af\u03b1.<\/p>\n<p>\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1. \u0395\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03b9 <strong>\u03c4\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<\/strong>, \u03c3\u03c9\u03c3\u03c4\u03cc\u03c2 \u03c7\u03c1\u03bf\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd, \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae \u03ba\u03b1\u03c0\u03bd\u03af\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2, \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c3\u03af\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03ba\u03c1\u03cd\u03bf, \u03c6\u03c5\u03c3\u03b9\u03ba\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03c3\u03c4\u03bf\u03bc\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c3\u03ba\u03ae\u03c3\u03b5\u03b9\u03c2, \u03c3\u03c9\u03c3\u03c4\u03ae \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b5\u03bd\u03ae \u03c3\u03c5\u03bd\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03bc\u03b5 <strong>\u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03bf<\/strong>, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03bc\u03b5 <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03bb\u03cc\u03b3\u03bf, \u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf, \u03bd\u03b5\u03c6\u03c1\u03bf\u03bb\u03cc\u03b3\u03bf, \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03bf\u03bb\u03cc\u03b3\u03bf \u03ae \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03bf<\/strong> \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 15 ==================== --><\/p>\n<section id=\"section-15\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">15<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b1\u03bd\u03ac \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03cc\u03c1\u03b3\u03b1\u03bd\u03bf<\/span><\/h2>\n<p>\u0393\u03b9\u03b1 \u03c4\u03bf <strong>Raynaud<\/strong>, \u03c3\u03c5\u03c7\u03bd\u03ac \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 <strong>\u03b1\u03b3\u03b3\u03b5\u03b9\u03bf\u03b4\u03b9\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ac<\/strong> \u03cc\u03c0\u03c9\u03c2 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ad\u03c2 \u03b1\u03c3\u03b2\u03b5\u03c3\u03c4\u03af\u03bf\u03c5. \u03a3\u03b5 \u03c0\u03b9\u03bf \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03bf\u03cd\u03bd <strong>PDE5 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2<\/strong> \u03ae \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ad\u03c2. \u038c\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd <strong>\u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03b9\u03ba\u03ac \u03ad\u03bb\u03ba\u03b7<\/strong>, \u03bf \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03cc\u03c3\u03bf \u03b7 \u03b5\u03c0\u03bf\u03cd\u03bb\u03c9\u03c3\u03b7 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03c0\u03bf\u03c6\u03c5\u03b3\u03ae \u03bd\u03ad\u03c9\u03bd \u03b2\u03bb\u03b1\u03b2\u03ce\u03bd, \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c3\u03c9\u03c3\u03c4\u03ae \u03c4\u03bf\u03c0\u03b9\u03ba\u03ae \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2.<\/p>\n<p>\u0393\u03b9\u03b1 <strong>\u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03af\u03bd\u03c9\u03c3\u03b7<\/strong> \u03ae \u03b5\u03bd\u03b5\u03c1\u03b3\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf, \u03bf \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2. \u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 <strong>SSc-ILD<\/strong> \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7, \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03cc\u03c0\u03c9\u03c2 <strong>\u03bc\u03c5\u03ba\u03bf\u03c6\u03b1\u03b9\u03bd\u03bf\u03bb\u03ac\u03c4\u03b7<\/strong>, <strong>\u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03c9\u03c3\u03c6\u03b1\u03bc\u03af\u03b4\u03b7<\/strong>, <strong>rituximab<\/strong>, \u03b5\u03bd\u03ce \u03c3\u03b5 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 <strong>nintedanib<\/strong> \u03ae <strong>tocilizumab<\/strong>. \u0397 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ae \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03ba\u03ae. \u0395\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 HRCT, \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03b2\u03ac\u03c1\u03c5\u03bd\u03c3\u03b7, \u03c4\u03b7\u03bd \u03c4\u03b1\u03c7\u03cd\u03c4\u03b7\u03c4\u03b1 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b1\u03bd\u03bf\u03c7\u03ae \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7<\/strong>, \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03bf\u03bc\u03ac\u03b4\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 <strong>\u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 PDE5<\/strong>, <strong>\u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ad\u03c2 \u03b5\u03bd\u03b4\u03bf\u03b8\u03b7\u03bb\u03af\u03bd\u03b7\u03c2<\/strong>, <strong>\u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03ba\u03c5\u03ba\u03bb\u03af\u03bd\u03b5\u03c2<\/strong> \u03ae \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ad\u03c2. \u0393\u03b9\u03b1 \u03c4\u03bf <strong>\u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc<\/strong> \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 <strong>PPI<\/strong>, \u03ba\u03b1\u03c4\u03ac \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 <strong>\u03c0\u03c1\u03bf\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac<\/strong>, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03b3\u03c9\u03b3\u03ae \u03b3\u03b9\u03b1 SIBO. \u0393\u03b9\u03b1 \u03c4\u03b7 <strong>\u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03ba\u03c1\u03af\u03c3\u03b7<\/strong>, \u03b7 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 <strong>ACE \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03ae. \u0395\u03b4\u03ce \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03ba\u03b1\u03b9 \u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7.<\/p>\n<p>\u03a3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae, \u03c4\u03b1\u03c7\u03ad\u03c9\u03c2 \u03b5\u03be\u03b5\u03bb\u03b9\u03c3\u03c3\u03cc\u03bc\u03b5\u03bd\u03b7 \u03bd\u03cc\u03c3\u03bf, \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1 \u03ba\u03ad\u03bd\u03c4\u03c1\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03b6\u03b7\u03c4\u03ae\u03c3\u03bf\u03c5\u03bd \u03b1\u03ba\u03cc\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ad\u03c2, \u03cc\u03c0\u03c9\u03c2 <strong>\u03b1\u03c5\u03c4\u03cc\u03bb\u03bf\u03b3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03bc\u03cc\u03c3\u03c7\u03b5\u03c5\u03c3\u03b7 \u03b1\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd<\/strong> \u03c3\u03b5 \u03c0\u03bf\u03bb\u03cd \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2. \u0391\u03c5\u03c4\u03ad\u03c2 \u03bf\u03b9 \u03b1\u03c0\u03bf\u03c6\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd \u03c4\u03b7 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03af\u03c7\u03bd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03ba\u03bb\u03b7\u03c1\u03bf\u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03c0\u03c1\u03bf\u03c7\u03c9\u03c1\u03ae\u03c3\u03b5\u03b9 \u03c0\u03bf\u03bb\u03cd \u03c0\u03ad\u03c1\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u00ab\u03b4\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c4\u03af\u03c0\u03bf\u03c4\u03b1 \u03bd\u03b1 \u03ba\u03ac\u03bd\u03bf\u03c5\u03bc\u03b5\u00bb.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 16 ==================== --><\/p>\n<section id=\"section-16\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">16<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u039a\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1, \u03ba\u03c1\u03cd\u03bf, \u03b4\u03ad\u03c1\u03bc\u03b1, \u03ac\u03c3\u03ba\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae<\/span><\/h2>\n<p>\u0397 \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1 \u03c3\u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1. \u0393\u03b9\u03b1 \u03c4\u03bf <strong>Raynaud<\/strong>, \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b7 <strong>\u03b8\u03b5\u03c1\u03bc\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c3\u03af\u03b1<\/strong>: \u03b3\u03ac\u03bd\u03c4\u03b9\u03b1, \u03ba\u03ac\u03bb\u03c4\u03c3\u03b5\u03c2, \u03c3\u03c4\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c1\u03bf\u03cd\u03c7\u03c9\u03bd, \u03b1\u03c0\u03bf\u03c6\u03c5\u03b3\u03ae \u03b1\u03c0\u03cc\u03c4\u03bf\u03bc\u03b7\u03c2 \u03ad\u03ba\u03b8\u03b5\u03c3\u03b7\u03c2 \u03c3\u03b5 \u03ba\u03c1\u03cd\u03bf, \u03ba\u03b1\u03bb\u03cc\u03c2 \u03b1\u03b5\u03c1\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b1\u03bb\u03bb\u03ac \u03cc\u03c7\u03b9 \u03c8\u03c5\u03c7\u03c1\u03cc \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03ba\u03b1\u03b9, \u03cc\u03c0\u03bf\u03c5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9, \u03b8\u03b5\u03c1\u03bc\u03b1\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03bc\u03b1\u03c4\u03b1. \u0397 \u03b1\u03c0\u03bf\u03c6\u03c5\u03b3\u03ae \u03ba\u03b1\u03c0\u03bd\u03af\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03bb\u03cd\u03c4\u03c9\u03c2 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ae.<\/p>\n<p>\u0393\u03b9\u03b1 \u03c4\u03bf <strong>\u03b4\u03ad\u03c1\u03bc\u03b1<\/strong>, \u03b2\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03b7 <strong>\u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03b5\u03bd\u03c5\u03b4\u03ac\u03c4\u03c9\u03c3\u03b7<\/strong>, \u03b7 \u03b1\u03c0\u03bf\u03c6\u03c5\u03b3\u03ae 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\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1. \u0397 \u03c6\u03c5\u03c3\u03b9\u03ba\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03b5\u03c1\u03b3\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1 \u03b1\u03c0\u2019 \u03cc\u03c3\u03bf \u03c0\u03b9\u03c3\u03c4\u03b5\u03cd\u03bf\u03c5\u03bd \u03c0\u03bf\u03bb\u03bb\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2.<\/p>\n<p>\u0397 <strong>\u03ac\u03c3\u03ba\u03b7\u03c3\u03b7<\/strong> \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03cc\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b9\u03c2 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae 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\u03b4\u03b5\u03bd \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c0\u03b1\u03bb\u03b9\u03bd\u03b4\u03c1\u03cc\u03bc\u03b7\u03c3\u03b7 \u03b2\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac. \u0391\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2, \u03b1\u03bd\u03b1\u03b9\u03bc\u03af\u03b1, \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03ae \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03bf \u03c6\u03bf\u03cd\u03c3\u03ba\u03c9\u03bc\u03b1, \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b4\u03c5\u03c3\u03b1\u03c0\u03bf\u03c1\u03c1\u03cc\u03c6\u03b7\u03c3\u03b7 \u03ae SIBO \u03ba\u03b1\u03b9, \u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af, \u03b4\u03b9\u03b1\u03b9\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 17 ==================== --><\/p>\n<section id=\"section-17\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">17<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0395\u03c1\u03b3\u03b1\u03c3\u03af\u03b1, \u03c3\u03c7\u03ad\u03c3\u03b5\u03b9\u03c2, \u03c8\u03c5\u03c7\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 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\u03ad\u03ba\u03b8\u03b5\u03c3\u03b7 \u03c3\u03b5 \u03c8\u03c5\u03c7\u03c1\u03cc \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd, \u03c3\u03b5 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ae \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7 \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7. \u039c\u03b5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c6\u03bf\u03c1\u03ad\u03c2 \u03b1\u03c1\u03ba\u03bf\u03cd\u03bd <strong>\u03bc\u03b9\u03ba\u03c1\u03ad\u03c2 \u03b5\u03c1\u03b3\u03bf\u03bd\u03bf\u03bc\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ad\u03c2<\/strong>, \u03ac\u03bb\u03bb\u03b1\u03c4\u03b5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03ba\u03b1\u03b8\u03b7\u03ba\u03cc\u03bd\u03c4\u03c9\u03bd.<\/p>\n<p>\u0397 <strong>\u03c8\u03c5\u03c7\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03b2\u03ac\u03c1\u03c5\u03bd\u03c3\u03b7<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ae. \u0397 \u03b1\u03b2\u03b5\u03b2\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5, \u03bf\u03b9 \u03b1\u03b9\u03c3\u03b8\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2, \u03b7 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7, \u03bf \u03c6\u03cc\u03b2\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2 \u03ae \u03c4\u03b7\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03bf\u03c5\u03bd \u03c3\u03b5 <strong>\u03ac\u03b3\u03c7\u03bf\u03c2<\/strong>, <strong>\u03ba\u03b1\u03c4\u03b1\u03b8\u03bb\u03b9\u03c0\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7<\/strong> \u03ae \u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc\u03c3\u03c5\u03c1\u03c3\u03b7. \u0391\u03c5\u03c4\u03ac \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u00ab\u03c5\u03c0\u03b5\u03c1\u03b2\u03bf\u03bb\u03ad\u03c2\u00bb. \u0395\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03b1\u03c1\u03ba\u03c4\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b9\u03b1\u03c2 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n<p>\u0397 <strong>\u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1<\/strong> \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9, \u03b1\u03bb\u03bb\u03ac \u03c3\u03c5\u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u2019 \u03cc\u03c3\u03bf \u03b8\u03b1 \u03ad\u03c0\u03c1\u03b5\u03c0\u03b5. \u03a0\u03cc\u03bd\u03bf\u03c2, \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7, \u03b4\u03c5\u03c3\u03c6\u03bf\u03c1\u03af\u03b1, \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ac \u03c0\u03c1\u03bf\u03b2\u03bb\u03ae\u03bc\u03b1\u03c4\u03b1, \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03ba\u03b1\u03b9 \u03c8\u03c5\u03c7\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03b2\u03ac\u03c1\u03c5\u03bd\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7 \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c5\u03c4\u03bf\u03c0\u03b5\u03c0\u03bf\u03af\u03b8\u03b7\u03c3\u03b7. \u0391\u03c5\u03c4\u03cc \u03c4\u03bf \u03b8\u03ad\u03bc\u03b1 \u03b1\u03be\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03c3\u03c5\u03b6\u03b7\u03c4\u03b9\u03ad\u03c4\u03b1\u03b9 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b1\u03bc\u03b7\u03c7\u03b1\u03bd\u03af\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03bf\u03bc\u03ac\u03b4\u03b1, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b6\u03c9\u03ae\u03c2 \u03ae \u03c4\u03b7 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b6\u03b5\u03c5\u03b3\u03b1\u03c1\u03b9\u03bf\u03cd.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 18 ==================== --><\/p>\n<section id=\"section-18\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">18<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7<\/span><\/h2>\n<p>\u0397 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c6\u03b9\u03ba\u03c4\u03ae \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1, \u03b1\u03bb\u03bb\u03ac \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 <strong>\u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7 \u03c3\u03cd\u03bb\u03bb\u03b7\u03c8\u03b7<\/strong>. \u03a4\u03bf \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03b6\u03b7\u03c4\u03bf\u03cd\u03bc\u03b5\u03bd\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03ba\u03c4\u03b9\u03bc\u03b7\u03b8\u03b5\u03af \u03b1\u03bd \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae<\/strong> \u03ba\u03b1\u03b9 \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2 \u03b1\u03c0\u03cc <strong>\u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2<\/strong>, <strong>\u03ba\u03b1\u03c1\u03b4\u03b9\u03ac<\/strong> \u03ae <strong>\u03bd\u03b5\u03c6\u03c1\u03bf\u03cd\u03c2<\/strong>. \u0395\u03be\u03af\u03c3\u03bf\u03c5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03bb\u03b5\u03b3\u03c7\u03b8\u03b5\u03af \u03b1\u03bd \u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ae \u03bc\u03b5 \u03ba\u03cd\u03b7\u03c3\u03b7 \u03ae \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03bd\u03c9\u03c1\u03af\u03c4\u03b5\u03c1\u03b1.<\/p>\n<p>\u0397 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03bb\u03cc \u03bd\u03b1 \u03be\u03b5\u03ba\u03b9\u03bd\u03ac \u03c3\u03b5 \u03c6\u03ac\u03c3\u03b7 \u03b5\u03bd\u03b5\u03c1\u03b3\u03ae\u03c2 \u03ae \u03c4\u03b1\u03c7\u03ad\u03c9\u03c2 \u03b5\u03be\u03b5\u03bb\u03b9\u03c3\u03c3\u03cc\u03bc\u03b5\u03bd\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5. \u039f \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 <strong>\u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03bf\u03c5<\/strong> \u03ba\u03b1\u03b9 <strong>\u03bc\u03b1\u03b9\u03b5\u03c5\u03c4\u03ae\u03c1\u03b1 \u03c5\u03c8\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03b1\u03c3\u03c6\u03b1\u03bb\u03ad\u03c3\u03c4\u03b5\u03c1\u03bf\u03c2 \u03b4\u03c1\u03cc\u03bc\u03bf\u03c2. \u039a\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03ba\u03cd\u03b7\u03c3\u03b7 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2, \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03b8\u03b5\u03ce\u03c1\u03b7\u03c3\u03b7 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd.<\/p>\n<p>\u039f\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03cc\u03c0\u03c9\u03c2 <strong>\u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03a0\u0391\u03a5<\/strong>, \u03b1\u03c5\u03be\u03ac\u03bd\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03b9 \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae. \u039c\u03b5\u03c4\u03ac \u03c4\u03bf\u03bd \u03c4\u03bf\u03ba\u03b5\u03c4\u03cc \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b5\u03c0\u03b1\u03bd\u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7, \u03b3\u03b9\u03b1\u03c4\u03af \u03b7 \u03bb\u03bf\u03c7\u03b5\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b5\u03c1\u03af\u03bf\u03b4\u03bf\u03c2 \u03cc\u03c0\u03bf\u03c5 \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b1\u03bd\u03b1\u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03c4\u03bf\u03cd\u03bd.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 19 ==================== --><\/p>\n<section id=\"section-19\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">19<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03ac\u03bd\u03bf \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2<\/span><\/h2>\n<p>\u0397 \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c3\u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b2\u03b5\u03bb\u03c4\u03b9\u03c9\u03b8\u03b5\u03af \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac, \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03bf\u03c5\u03bc\u03b5 \u03bd\u03c9\u03c1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf, \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03bc\u03b5 \u03c0\u03b9\u03bf \u03b5\u03bd\u03b5\u03c1\u03b3\u03ac \u03c4\u03b1 \u03cc\u03c1\u03b3\u03b1\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c4\u03bf\u03c5\u03bc\u03b5 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ad\u03c2. \u03a0\u03b1\u03c1\u2019 \u03cc\u03bb\u03b1 \u03b1\u03c5\u03c4\u03ac, \u03b7 \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7 <strong>\u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03af\u03b4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03cc\u03bb\u03bf\u03c5\u03c2<\/strong>. \u0395\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03c4\u03cd\u03c0\u03bf \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5, \u03c4\u03bf \u03c0\u03bf\u03b9\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd, \u03b1\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03c7\u03b8\u03b5\u03af ILD \u03ae \u03a0\u0391\u03a5, \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b4\u03b1\u03ba\u03c4\u03c5\u03bb\u03b9\u03ba\u03ac \u03ad\u03bb\u03ba\u03b7, \u03c0\u03cc\u03c3\u03bf \u03bd\u03c9\u03c1\u03af\u03c2 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03ce\u03c2 \u03b1\u03bd\u03c4\u03b1\u03c0\u03bf\u03ba\u03c1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03c3\u03c4\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c0\u03bb\u03ac\u03bd\u03bf.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7, \u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 <strong>\u03c4\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2<\/strong>, <strong>\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2<\/strong>, \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c0\u03b1\u03bb\u03b9\u03bd\u03b4\u03c1\u03cc\u03bc\u03b7\u03c3\u03b7 \u03ae \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03b4\u03b9\u03ba\u03cc <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc<\/strong> \u03ba\u03b1\u03b9 <strong>\u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc<\/strong> \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf. \u039f\u03b9 \u03bd\u03b5\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u03b4\u03af\u03bd\u03bf\u03c5\u03bd \u03ad\u03bc\u03c6\u03b1\u03c3\u03b7 \u03c3\u03c4\u03bf <strong>\u03b5\u03c4\u03ae\u03c3\u03b9\u03bf screening \u03b3\u03b9\u03b1 \u03a0\u0391\u03a5<\/strong> \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd <strong>\u03b5\u03c4\u03ae\u03c3\u03b9\u03b1 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7<\/strong> \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7, \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b9 \u03b1\u03bd \u03b4\u03b5\u03bd \u03ad\u03c7\u03bf\u03c5\u03bd \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1. :contentReference[oaicite:1]{index=1}<\/p>\n<p>\u039f \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03b2\u03bf\u03b7\u03b8\u03ac\u03b5\u03b9 \u03c0\u03bf\u03bb\u03cd \u03cc\u03c4\u03b1\u03bd \u03ba\u03c1\u03b1\u03c4\u03ac \u03ad\u03bd\u03b1 \u03b1\u03c0\u03bb\u03cc \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03cc \u03b1\u03c1\u03c7\u03b5\u03af\u03bf \u03bc\u03b5 <strong>\u03c0\u03af\u03b5\u03c3\u03b7<\/strong>, \u03bd\u03ad\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03b5\u03c0\u03b5\u03b9\u03c3\u03cc\u03b4\u03b9\u03b1 Raynaud, \u03ad\u03bb\u03ba\u03b7, \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1, \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2 \u03b7\u03bc\u03b5\u03c1\u03bf\u03bc\u03b7\u03bd\u03af\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd. \u0388\u03c4\u03c3\u03b9 \u03bf \u03b5\u03c0\u03b1\u03bd\u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b1\u03c0\u03bf\u03b4\u03bf\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bd\u03c9\u03c1\u03af\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b9\u03ba\u03c1\u03ad\u03c2 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03b8\u03b1 \u03c0\u03b5\u03c1\u03bd\u03bf\u03cd\u03c3\u03b1\u03bd \u03b1\u03c0\u03b1\u03c1\u03b1\u03c4\u03ae\u03c1\u03b7\u03c4\u03b5\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 20 ==================== --><\/p>\n<section id=\"section-20\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">20<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b5\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/span><\/h2>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc;<\/summary>\n<p>\u038c\u03c7\u03b9. \u0397 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1 \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c0\u03bf\u03bb\u03cd \u03b1\u03c0\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae. \u039a\u03ac\u03c0\u03bf\u03b9\u03bf\u03b9 \u03ad\u03c7\u03bf\u03c5\u03bd \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 Raynaud \u03ba\u03b1\u03b9 \u03ae\u03c0\u03b9\u03b1 \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae, \u03b5\u03bd\u03ce \u03ac\u03bb\u03bb\u03bf\u03b9 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b5\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2, \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac \u03ae \u03bd\u03b5\u03c6\u03c1\u03bf\u03cd\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0391\u03bd \u03ad\u03c7\u03c9 Raynaud, \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ad\u03c7\u03c9 \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1;<\/summary>\n<p>\u038c\u03c7\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b1. \u03a4\u03bf Raynaud \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03c9\u03c4\u03bf\u03c0\u03b1\u03b8\u03ad\u03c2. \u038c\u03c4\u03b1\u03bd \u03cc\u03bc\u03c9\u03c2 \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b5 \u03c0\u03c1\u03b7\u03c3\u03bc\u03ad\u03bd\u03b1 \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1, \u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c4\u03c1\u03b9\u03c7\u03bf\u03b5\u03b9\u03b4\u03bf\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7 \u03ae \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1, \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a0\u03bf\u03b9\u03bf \u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03c0\u03b9\u03bf \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc;<\/summary>\n<p>\u0394\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03bc\u03cc\u03bd\u03bf. \u03a4\u03b1 \u03c0\u03b9\u03bf \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ac \u03b5\u03af\u03bd\u03b1\u03b9 ANA, anti-centromere, anti\u2013Scl-70 \u03ba\u03b1\u03b9 anti\u2013RNA polymerase III, \u03bc\u03b5 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03c3\u03b5\u03b9\u03c2 \u03c4\u03bf \u03ba\u03b1\u03b8\u03ad\u03bd\u03b1.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac;<\/summary>\n<p>\u0394\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03cc\u03bb\u03bf\u03c5\u03c2, \u03b1\u03bb\u03bb\u03ac \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03c5\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03c0\u03c1\u03bf\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03bc\u03b5\u03c4\u03c1\u03ac\u03c9 \u03c4\u03b7\u03bd \u03c0\u03af\u03b5\u03c3\u03ae \u03bc\u03bf\u03c5 \u03c3\u03c4\u03bf \u03c3\u03c0\u03af\u03c4\u03b9;<\/summary>\n<p>\u039d\u03b1\u03b9, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b1\u03bd \u03ad\u03c7\u03b5\u03c4\u03b5 \u03b4\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03bc\u03bf\u03c1\u03c6\u03ae \u03ae \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \u0397 \u03c4\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2 \u03b2\u03bf\u03b7\u03b8\u03ac \u03bd\u03b1 \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b1 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b5\u03c2 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ae.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039c\u03c0\u03bf\u03c1\u03ce \u03bd\u03b1 \u03b3\u03c5\u03bc\u03bd\u03ac\u03b6\u03bf\u03bc\u03b1\u03b9;<\/summary>\n<p>\u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03bd\u03b1\u03b9, \u03bc\u03b5 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03c3\u03c4\u03bf \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03b1\u03bd\u03c4\u03bf\u03c7\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b9\u03c2 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ad\u03c2 \u03ae \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03c3\u03b5\u03b9\u03c2. \u0397 \u03ae\u03c0\u03b9\u03b1 \u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03b1 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03b4\u03b9\u03b1\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c9\u03c6\u03ad\u03bb\u03b9\u03bc\u03b5\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0397 \u03c0\u03b1\u03bb\u03b9\u03bd\u03b4\u03c1\u03cc\u03bc\u03b7\u03c3\u03b7 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1;<\/summary>\n<p>\u039d\u03b1\u03b9. \u0397 \u03b4\u03c5\u03c3\u03ba\u03b9\u03bd\u03b7\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03bf\u03b9\u03c3\u03bf\u03c6\u03ac\u03b3\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b7 \u0393\u039f\u03a0\u039d \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7, \u03cc\u03c7\u03b9 \u03b1\u03c0\u03bb\u03ae \u03c5\u03c0\u03bf\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03c9\u03c2 \u201c\u03b5\u03c5\u03b1\u03af\u03c3\u03b8\u03b7\u03c4\u03bf \u03c3\u03c4\u03bf\u03bc\u03ac\u03c7\u03b9\u201d.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0397 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7 \u03b1\u03c0\u03b1\u03b3\u03bf\u03c1\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9;<\/summary>\n<p>\u038c\u03c7\u03b9, \u03b1\u03bb\u03bb\u03ac \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c3\u03c7\u03b5\u03b4\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03b5\u03ba\u03c4\u03b9\u03ba\u03ac. \u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae \u03bd\u03cc\u03c3\u03bf\u03c2, \u03c0\u03c1\u03bf\u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c0\u03bd\u03b5\u03c5\u03bc\u03cc\u03bd\u03c9\u03bd\/\u03ba\u03b1\u03c1\u03b4\u03b9\u03ac\u03c2\/\u03bd\u03b5\u03c6\u03c1\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b1\u03bd\u03b1\u03b8\u03b5\u03ce\u03c1\u03b7\u03c3\u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7 \u03c3\u03cd\u03bb\u03bb\u03b7\u03c8\u03b7.<\/p>\n<\/details>\n<\/section>\n<p><!-- ==================== SECTION 21 ==================== --><\/p>\n<section id=\"section-21\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">21<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/span><\/h2>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 10px 0 16px;\">\n<ul style=\"margin: 0; padding-left: 18px;\">\n<li style=\"margin: 0 0 8px;\">\u03a4\u03bf \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf\u03c2<\/strong>, \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1.<\/li>\n<li style=\"margin: 0 0 8px;\">\u03a4\u03bf <strong>Raynaud<\/strong>, \u03c4\u03b1 <strong>\u03c0\u03c1\u03b7\u03c3\u03bc\u03ad\u03bd\u03b1\/\u03c3\u03c6\u03b9\u03c7\u03c4\u03ac \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1<\/strong>, \u03b7 <strong>\u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1<\/strong> \u03ba\u03b1\u03b9 \u03bf\u03b9 <strong>\u03ba\u03b1\u03bf\u03cd\u03c1\u03b5\u03c2<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03be\u03af\u03b6\u03bf\u03c5\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf.<\/li>\n<li style=\"margin: 0 0 8px;\">\u03a4\u03b1 <strong>anti-centromere<\/strong>, <strong>anti\u2013Scl-70<\/strong> \u03ba\u03b1\u03b9 <strong>anti\u2013RNA polymerase III<\/strong> \u03b2\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03c0\u03bf\u03bb\u03cd \u03c3\u03c4\u03b7 \u03c7\u03b1\u03c1\u03c4\u03bf\u03b3\u03c1\u03ac\u03c6\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c4\u03cd\u03c0\u03bf\u03c5 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/li>\n<li style=\"margin: 0 0 8px;\">\u0397 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03cc\u03bd\u03c9\u03bd, \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03b5\u03c6\u03c1\u03ce\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae<\/strong>, \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ae\u03c0\u03b9\u03b1.<\/li>\n<li style=\"margin: 0 0 8px;\">\u0397 <strong>\u03b1\u03c0\u03cc\u03c4\u03bf\u03bc\u03b7 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2<\/strong> \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03c3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 <strong>\u03ac\u03bc\u03b5\u03c3\u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7<\/strong>.<\/li>\n<li style=\"margin: 0 0 8px;\">\u0397 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7<\/strong> \u03ba\u03b1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ad\u03c2 \u03b1\u03c0\u03cc \u03cc,\u03c4\u03b9 \u03c0\u03b1\u03bb\u03b1\u03b9\u03cc\u03c4\u03b5\u03c1\u03b1.<\/li>\n<li style=\"margin: 0;\">\u0397 <strong>\u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03b1\u03c0\u03cc \u03b9\u03b1\u03c4\u03c1\u03cc<\/strong> \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1, \u03b3\u03b9\u03b1\u03c4\u03af \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1.<\/li>\n<\/ul>\n<\/div>\n<\/section>\n<p><!-- ==================== SECTION 22 ==================== --><\/p>\n<section id=\"section-22\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(135deg,#f1f5f9 0%,#9ca3af 100%); border-radius: 10px; transform: rotate(45deg); box-shadow: 0 4px 10px rgba(0,0,0,0.10), inset 0 1px 1px rgba(255,255,255,0.85); flex: 0 0 36px;\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">22<\/span><\/span> <span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03c1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd &amp; \u03b2\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/span><\/h2>\n<p style=\"margin: 0 0 14px;\">\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03b9\u03b1\u03c4\u03c1\u03cc \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03cc \u03bc\u03b1\u03c2. \u039c\u03c0\u03bf\u03c1\u03b5\u03af\u03c4\u03b5 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03c3\u03b5\u03c4\u03b5 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ae \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.<\/p>\n<div style=\"background: #fdf2f2; border: 2px solid #b70000; border-radius: 14px; padding: 18px; text-align: center;\">\n<div><strong>\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03c3\u03ba\u03bb\u03b7\u03c1\u03bf\u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 (ANA, anti-centromere, anti\u2013Scl-70, anti\u2013RNA polymerase III \u03ba.\u03ac.) \u03ae \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf:<\/strong><\/div>\n<div style=\"display: flex; gap: 10px; justify-content: center; flex-wrap: wrap; margin-top: 10px;\"><a style=\"background: #b70000; color: #fff; padding: 12px 18px; border-radius: 12px; text-decoration: none; font-weight: 600; display: inline-flex; align-items: center; justify-content: center; white-space: nowrap; width: 200px; height: 44px;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"nofollow noopener\">\ud83d\udcd8 \u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd<\/a> <a style=\"background: #b70000; color: #fff; padding: 12px 18px; border-radius: 12px; text-decoration: none; font-weight: 600; display: inline-flex; align-items: center; justify-content: center; white-space: nowrap; width: 200px; height: 44px;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/about-us\/appointments\/\" target=\"_blank\" rel=\"nofollow noopener\">\ud83d\udcc5 \u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd \u03a4\u03ce\u03c1\u03b1<\/a><\/div>\n<div style=\"margin-top: 10px; color: #374151;\">\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n<\/div>\n<div style=\"margin-top: 18px; border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 6px; line-height: 1.35; font-size: 14px;\">Del Galdo F, Lescoat A, Khanna D, et al. <em>EULAR recommendations for the treatment of systemic sclerosis: 2023 update.<\/em><br \/>\n<a href=\"https:\/\/ard.eular.org\/article\/S0003-4967(24)00584-3\/fulltext\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/ard.eular.org\/article\/S0003-4967(24)00584-3\/fulltext<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">Denton CP, De Lorenzis E, Roblin E, et al. <em>The 2024 British Society for Rheumatology guideline for management of systemic sclerosis\u2014executive summary.<\/em><br \/>\n<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11534113\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11534113\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">van den Hoogen F, Khanna D, Fransen J, et al. <em>2013 classification criteria for systemic sclerosis: an ACR\/EULAR collaborative initiative.<\/em><br \/>\n<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3930146\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3930146\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">Volkmann ER, Allanore Y. <em>Systemic sclerosis.<\/em> <em>Lancet<\/em> \/ review summary on PubMed.<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36442487\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/36442487\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">American College of Rheumatology. <em>Scleroderma \u2013 patient information.<\/em><br \/>\n<a href=\"https:\/\/rheumatology.org\/patients\/scleroderma\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/rheumatology.org\/patients\/scleroderma<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">Mayo Clinic. <em>Scleroderma \u2013 symptoms and causes.<\/em><br \/>\n<a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/scleroderma\/symptoms-causes\/syc-20351952\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.mayoclinic.org\/diseases-conditions\/scleroderma\/symptoms-causes\/syc-20351952<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">Mayo Clinic. <em>Scleroderma \u2013 diagnosis and treatment.<\/em><br \/>\n<a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/scleroderma\/diagnosis-treatment\/drc-20351957\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.mayoclinic.org\/diseases-conditions\/scleroderma\/diagnosis-treatment\/drc-20351957<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">National Center for Biotechnology Information. <em>Scleroderma and Renal Crisis.<\/em><br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK482424\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK482424\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\"><strong>\u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u2013 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u039b\u03b1\u03bc\u03af\u03b1<\/strong><br \/>\n<a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"noopener\">https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/<\/a><\/div>\n<div style=\"background: #f1f5f9; border-left: 4px solid #2563eb; padding: 10px 14px; border-radius: 8px; margin-top: 10px;\"><strong style=\"color: #1d4ed8;\">\u0395\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03bc\u03ad\u03bb\u03b5\u03b9\u03b1:<\/strong><br \/>\n\u0394\u03c1. \u03a0\u03b1\u03bd\u03c4\u03b5\u03bb\u03ae\u03c2 \u0391\u03bd\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03cc\u03c0\u03bf\u03c5\u03bb\u03bf\u03c2, \u0399\u03b1\u03c4\u03c1\u03cc\u03c2 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u2013 \u0392\u03b9\u03bf\u03c0\u03b1\u03b8\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2<br \/>\n\u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u039b\u03b1\u03bc\u03af\u03b1\u03c2, \u0388\u03c3\u03bb\u03b9\u03bd 19, \u039b\u03b1\u03bc\u03af\u03b1 35100<br \/>\n\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n<\/section>\n<\/article>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u03a3\u03ba\u03bb\u03b7\u03c1\u03cc\u03b4\u03b5\u03c1\u03bc\u03b1 (\u03a3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03a3\u03ba\u03bb\u03ae\u03c1\u03c5\u03bd\u03c3\u03b7): \u03a3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1, \u0395\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u0394\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7: 22 \u039f\u03ba\u03c4\u03c9\u03b2\u03c1\u03af\u03bf\u03c5 2025 \u2022 \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 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