{"id":6591,"date":"2025-10-20T10:39:25","date_gmt":"2025-10-20T07:39:25","guid":{"rendered":"https:\/\/mikrobiologikolamia.gr\/staging\/?p=6591"},"modified":"2026-05-06T12:24:03","modified_gmt":"2026-05-06T09:24:03","slug":"anti-xa-anti-factor-xa-timi-timing-stoxoi-ermineia","status":"publish","type":"post","link":"https:\/\/mikrobiologikolamia.gr\/staging\/anti-xa-anti-factor-xa-timi-timing-stoxoi-ermineia\/","title":{"rendered":"Anti-Xa (Anti\u2013Factor Xa): \u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9, \u03a4\u03b9\u03bc\u03ad\u03c2 &#038; \u03a3\u03c4\u03cc\u03c7\u03bf\u03b9, \u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 | \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u039b\u03b1\u03bc\u03af\u03b1"},"content":{"rendered":"<h1 style=\"font-size: 30px; font-weight: 800; margin: 18px 0 6px; line-height: 1.2; color: #111827;\">Anti-Xa: \u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u0391\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u0397\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 (UFH, LMWH, Fondaparinux)<\/h1>\n<div style=\"margin: 10px 0 12px; font-size: 13px; color: #6b7280;\">\u0394\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7: <time datetime=\"2026-01-31T00:00:00+02:00\">31 \u0399\u03b1\u03bd\u03bf\u03c5\u03b1\u03c1\u03af\u03bf\u03c5 2026<\/time> \u2022 \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7: <time datetime=\"2026-01-31T00:00:00+02:00\">31 \u0399\u03b1\u03bd\u03bf\u03c5\u03b1\u03c1\u03af\u03bf\u03c5 2026<\/time><\/div>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0 18px;\"><strong>\u03a3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7 \u03c0\u03b5\u03c1\u03af\u03bb\u03b7\u03c8\u03b7:<\/strong><\/p>\n<p style=\"margin: 6px 0 0; line-height: 1.7;\">\u0397 <strong>Anti-Xa<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b5\u03ba\u03c4\u03b9\u03bc\u03b7\u03b8\u03b5\u03af \u03c0\u03cc\u03c3\u03bf \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03b4\u03c1\u03b1 \u03b7 <strong>\u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7<\/strong> \u03c3\u03c4\u03bf\u03bd \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc \u03c0\u03ae\u03be\u03b7\u03c2. \u0388\u03c7\u03b5\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd \u03b7 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03c3\u03b5 UFH, LMWH \u03ba\u03b1\u03b9, \u03bc\u03b5 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b7 \u03b2\u03b1\u03b8\u03bc\u03bf\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7, fondaparinux.<\/p>\n<p style=\"margin: 6px 0 0; line-height: 1.7;\">\u03a4\u03bf \u03c0\u03b9\u03bf \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03bf \u03c3\u03b7\u03bc\u03b5\u03af\u03bf \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b7 \u03c4\u03b9\u03bc\u03ae, \u03b1\u03bb\u03bb\u03ac \u03b7 <strong>\u03c3\u03c9\u03c3\u03c4\u03ae \u03ce\u03c1\u03b1 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2<\/strong>. \u0393\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03bf\u03cd \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b5\u03c2 \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 4 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7, \u03b5\u03bd\u03ce \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03ad\u03b2\u03b9\u03b1 UFH \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c6\u03bf\u03cd \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03bf \u03c1\u03c5\u03b8\u03bc\u03cc\u03c2 \u03ad\u03b3\u03c7\u03c5\u03c3\u03b7\u03c2.<\/p>\n<p style=\"margin: 6px 0 0; line-height: 1.7;\">\u0397 Anti-Xa \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7. \u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf, \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7, \u03c4\u03b7\u03bd \u03ce\u03c1\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2, \u03c4\u03b7 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03c4\u03bf \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2, \u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1 \u03ae \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b9\u03c2 \u03c3\u03c5\u03bd\u03bf\u03b4\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2.<\/p>\n<\/div>\n<p style=\"line-height: 1.8; color: #111827; margin: 10px 0 16px;\">\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 <strong>Anti-Xa<\/strong> \u03ad\u03c7\u03b5\u03b9 \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03cc \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7 \u03c3\u03cd\u03b3\u03c7\u03c1\u03bf\u03bd\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03bc\u03b5 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03bc\u03b5\u03c4\u03c1\u03ac \u03c0\u03b9\u03bf \u03ac\u03bc\u03b5\u03c3\u03b1 \u03c4\u03b7 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c0\u03b1\u03bb\u03b1\u03b9\u03cc\u03c4\u03b5\u03c1\u03bf\u03c5\u03c2, \u03ad\u03bc\u03bc\u03b5\u03c3\u03bf\u03c5\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2. \u03a3\u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03c0\u03c1\u03ac\u03be\u03b7 \u03b2\u03bf\u03b7\u03b8\u03ac \u03c4\u03bf\u03bd \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03b1 \u03b9\u03b1\u03c4\u03c1\u03cc \u03bd\u03b1 \u03b1\u03c0\u03b1\u03bd\u03c4\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03c0\u03bf\u03bb\u03cd \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1: \u03b7 \u03b4\u03cc\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03b1\u03c1\u03ba\u03ae\u03c2, \u03b1\u03bd\u03b5\u03c0\u03b1\u03c1\u03ba\u03ae\u03c2 \u03ae \u03c5\u03c0\u03b5\u03c1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c4\u03b7 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae;<\/p>\n<p style=\"line-height: 1.8; color: #111827; margin: 10px 0 16px;\">\u0397 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1. \u03a7\u03b1\u03bc\u03b7\u03bb\u03ae \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c6\u03ae\u03c3\u03b5\u03b9 \u03c4\u03bf\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03b5\u03ba\u03c4\u03b5\u03b8\u03b5\u03b9\u03bc\u03ad\u03bd\u03bf \u03c3\u03b5 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7, \u03b5\u03bd\u03ce \u03c5\u03c0\u03b5\u03c1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1\u03c2. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03b7 Anti-Xa \u03ad\u03c7\u03b5\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1 \u03c3\u03b5 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03bf\u03c5 \u03b7 \u03c4\u03c5\u03c0\u03b9\u03ba\u03ae \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c0\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bc\u03b5 \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1 \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1: \u03ba\u03cd\u03b7\u03c3\u03b7, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03b1\u03ba\u03c1\u03b1\u03af\u03bf \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2, \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac, \u03b5\u03bd\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, ECMO, \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03ae \u03b1\u03c3\u03c5\u03bc\u03c6\u03c9\u03bd\u03af\u03b1 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03b4\u03cc\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/aptt-exetasi-aimatos\/\">aPTT<\/a>.<\/p>\n<p style=\"line-height: 1.8; color: #111827; margin: 10px 0 16px;\">\u039f \u03bf\u03b4\u03b7\u03b3\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af \u03b5\u03be\u03b7\u03b3\u03b5\u03af \u03c0\u03cc\u03c4\u03b5 \u03ad\u03c7\u03b5\u03b9 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7, \u03c0\u03ce\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ac \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1, \u03c0\u03bf\u03b9\u03bf\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03b5\u03b9\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03bf\u03af \u03c3\u03c4\u03cc\u03c7\u03bf\u03b9, \u03c0\u03bf\u03b9\u03b1 \u03bb\u03ac\u03b8\u03b7 \u03b1\u03bb\u03bb\u03bf\u03b9\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03ce\u03c2 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03b7 Anti-Xa \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03cc\u03c0\u03c9\u03c2 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/inr-exetasi\/\">INR<\/a>, <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/d-dimeri-d-dimers-ti-einai-giati-afxanontai-kai-pote-einai-anisychitika\/\">D-Dimer<\/a>, <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/antithrombin-iii-exetasi\/\">\u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7<\/a>, \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/thromvofilia\/\">\u03b8\u03c1\u03bf\u03bc\u03b2\u03bf\u03c6\u03b9\u03bb\u03af\u03b1\u03c2<\/a> \u03ba\u03b1\u03b9 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1.<\/p>\n<nav id=\"toc\" style=\"background: #f9fafb; border: 1px solid #e5e7eb; border-radius: 14px; padding: 16px 18px; margin: 22px 0;\" aria-label=\"\u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1\"><strong>\u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1<\/strong><\/p>\n<ol style=\"margin: 10px 0 0 18px; line-height: 1.9;\">\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec1\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 Anti-Xa<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec2\">\u03a0\u03cc\u03c4\u03b5 \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b7 Anti-Xa<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec3\">\u03a0\u03cc\u03c4\u03b5 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec4\">\u03a4\u03b9\u03bc\u03ad\u03c2 Anti-Xa \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03bf\u03af \u03c3\u03c4\u03cc\u03c7\u03bf\u03b9<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec5\">UFH, LMWH \u03ba\u03b1\u03b9 fondaparinux<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec6\">\u03a0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec7\">\u0395\u03b9\u03b4\u03b9\u03ba\u03bf\u03af \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03bf\u03af \u03ba\u03b1\u03b9 \u03ba\u03cd\u03b7\u03c3\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec8\">\u03a0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf-\u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec9\">Anti-Xa vs aPTT, INR \u03ba\u03b1\u03b9 calibrated assays<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec10\">Anti-Xa \u03c3\u03c4\u03b7\u03bd \u03b5\u03bd\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae, ECMO \u03ba\u03b1\u03b9 \u03b2\u03b1\u03c1\u03b9\u03ac \u03bd\u03cc\u03c3\u03bf<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec11\">\u0391\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03c8\u03b5\u03c5\u03b4\u03ce\u03c2 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ad\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec12\">\u03a3\u03c5\u03c7\u03bd\u03ac \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ac \u03c3\u03c6\u03ac\u03bb\u03bc\u03b1\u03c4\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec13\">\u03a0\u03cc\u03c4\u03b5 \u03b4\u03b5\u03bd \u03b5\u03bd\u03b4\u03b5\u03af\u03ba\u03bd\u03c5\u03c4\u03b1\u03b9 \u03b7 Anti-Xa<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec14\">Anti-Xa \u03c3\u03b5 30\u2019\u2019 \u03b3\u03b9\u03b1 \u03b5\u03c0\u03b1\u03b3\u03b3\u03b5\u03bb\u03bc\u03b1\u03c4\u03af\u03b5\u03c2 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#faq\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b5\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec16\">\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#sec17\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03c1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd &amp; \u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/a><\/li>\n<\/ol>\n<\/nav>\n<hr style=\"border: 0; border-top: 2px solid #d1d5db; margin: 18px 0;\" \/>\n<p><!-- ==================== SECTION 1 ==================== --><\/p>\n<h2 id=\"sec1\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">1<\/span><\/span>\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 Anti-Xa<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 Anti-Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03b9\u03bc\u03cc\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03bc\u03b5\u03c4\u03c1\u03ac \u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ce\u03bd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b1\u03bd\u03b1\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 Xa.<\/strong> \u03a3\u03c4\u03b7\u03bd \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af \u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03c4\u03b7\u03c2 \u03bc\u03b7 \u03ba\u03bb\u03b1\u03c3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 (UFH), \u03c4\u03c9\u03bd \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03bf\u03cd \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2 \u03b7\u03c0\u03b1\u03c1\u03b9\u03bd\u03ce\u03bd (LMWH) \u03ba\u03b1\u03b9, \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1 \u03b2\u03b1\u03b8\u03bc\u03bf\u03bd\u03bf\u03bc\u03b7\u03bc\u03ad\u03bd\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2, \u03c4\u03bf\u03c5 fondaparinux.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u039f \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03ad\u03bd\u03b6\u03c5\u03bc\u03bf \u03c4\u03bf\u03c5 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd \u03c0\u03ae\u03be\u03b7\u03c2. \u03a3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03c4\u03c1\u03bf\u03c0\u03ae \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2 \u03c3\u03b5 \u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7, \u03ac\u03c1\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c4\u03b5\u03bb\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03c3\u03c7\u03b7\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03cc \u03b8\u03c1\u03cc\u03bc\u03b2\u03bf\u03c5. \u038c\u03c4\u03b1\u03bd \u03c7\u03bf\u03c1\u03b7\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7, \u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 Xa \u03b1\u03bd\u03b1\u03c3\u03c4\u03ad\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2. \u0397 Anti-Xa \u03c0\u03c1\u03bf\u03c3\u03c0\u03b1\u03b8\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03c4\u03b1\u03c6\u03c1\u03ac\u03c3\u03b5\u03b9 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c3\u03b5 \u03b1\u03c1\u03b9\u03b8\u03bc\u03b7\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u03a4\u03b9 \u03bc\u03b5\u03c4\u03c1\u03ac \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac:<\/strong> \u0397 Anti-Xa \u03b4\u03b5\u03bd \u03bc\u03b5\u03c4\u03c1\u03ac \u00ab\u03c0\u03cc\u03c3\u03bf \u03b1\u03c1\u03b1\u03b9\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03b1\u03af\u03bc\u03b1\u00bb. \u039c\u03b5\u03c4\u03c1\u03ac \u03c0\u03cc\u03c3\u03bf \u03b1\u03bd\u03b1\u03c3\u03c4\u03ad\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03bf \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 Xa \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1.<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf, \u03c3\u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2 \u03c0\u03c1\u03bf\u03c3\u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae \u03c0\u03bf\u03c3\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 Xa \u03ba\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03c7\u03c1\u03c9\u03bc\u03b1\u03c4\u03bf\u03bc\u03b5\u03c4\u03c1\u03b9\u03ba\u03cc \u03c5\u03c0\u03cc\u03c3\u03c4\u03c1\u03c9\u03bc\u03b1. \u038c\u03c3\u03bf \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2, \u03c4\u03cc\u03c3\u03bf \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03bd\u03b1\u03c3\u03c4\u03ad\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03bf \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 Xa \u03ba\u03b1\u03b9 \u03c4\u03cc\u03c3\u03bf \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c7\u03c1\u03ce\u03bc\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03c4\u03b1\u03b9. \u03a4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03b5\u03c4\u03b1\u03c4\u03c1\u03ad\u03c0\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bc\u03bf\u03bd\u03ac\u03b4\u03b5\u03c2 <strong>IU\/mL<\/strong>, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03b4\u03b9\u03b5\u03b8\u03bd\u03b5\u03af\u03c2 \u03bc\u03bf\u03bd\u03ac\u03b4\u03b5\u03c2 \u03b1\u03bd\u03ac mL.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03be\u03af\u03b1 \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b5\u03c3\u03c4\u03b9\u03ac\u03b6\u03b5\u03b9 \u03c0\u03b9\u03bf \u03ac\u03bc\u03b5\u03c3\u03b1 \u03c3\u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2. \u03a4\u03bf <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/aptt-exetasi-aimatos\/\">aPTT<\/a> \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf \u03c4\u03b5\u03c3\u03c4 \u03c0\u03ae\u03be\u03b7\u03c2, \u03b1\u03bb\u03bb\u03ac \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c0\u03bf\u03bb\u03bb\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03c0\u03ae\u03be\u03b7\u03c2, \u03bf\u03be\u03b5\u03af\u03b1 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03b1\u03bd\u03c4\u03b9\u03b4\u03c1\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03b1, lupus anticoagulant, \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf-\u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03ac \u03c3\u03c6\u03ac\u03bb\u03bc\u03b1\u03c4\u03b1. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03c3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03b7 Anti-Xa \u03b4\u03af\u03bd\u03b5\u03b9 \u03c0\u03b9\u03bf \u03ba\u03b1\u03b8\u03b1\u03c1\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ad\u03bd\u03c4\u03b1\u03c3\u03b7\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0391\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 Anti-Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b7. \u03a3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03bf\u03cd\u03c2 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c4\u03c5\u03c0\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae LMWH \u03b4\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7. \u0397 \u03b1\u03be\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c8\u03b9\u03bc\u03b7 \u03ae \u03cc\u03c4\u03b1\u03bd \u03b7 \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03af\u03ba\u03b5\u03c5\u03c3\u03b7.<\/p>\n<p><!-- ==================== SECTION 2 ==================== --><\/p>\n<h2 id=\"sec2\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">2<\/span><\/span>\u03a0\u03cc\u03c4\u03b5 \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b7 Anti-Xa<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 Anti-Xa \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03bf \u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b1\u03ba\u03c1\u03b9\u03b2\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ae \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03ce\u03c3\u03b5\u03b9 \u03b7 \u03b1\u03c0\u03bb\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03ae \u03c4\u03bf aPTT.<\/strong> \u0394\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 screening \u03b3\u03b9\u03b1 \u03b8\u03c1\u03bf\u03bc\u03b2\u03ce\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03b5\u03bd\u03b9\u03ba\u03cc\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03b9\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03c5\u03c7\u03bd\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03ad\u03b2\u03b9\u03b1\u03c2 UFH \u03cc\u03c4\u03b1\u03bd \u03c4\u03bf aPTT \u03b4\u03b5\u03bd \u03c3\u03c5\u03bc\u03b2\u03b1\u03b4\u03af\u03b6\u03b5\u03b9 \u03bc\u03b5 \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7 \u03ae \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1. \u0391\u03c5\u03c4\u03cc \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b5\u03af \u03c3\u03b5 \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03c5\u03cc\u03bc\u03b5\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2, \u03c3\u03b5 \u03c3\u03ae\u03c8\u03b7, \u03c3\u03b5 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7, \u03c3\u03b5 \u03c5\u03c8\u03b7\u03bb\u03cc \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 VIII, \u03c3\u03b5 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 lupus anticoagulant \u03ae \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2 \u03c4\u03c9\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03c0\u03ae\u03be\u03b7\u03c2. \u03a3\u03b5 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2, \u03b7 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c3\u03c6\u03b1\u03bb\u03ad\u03c3\u03c4\u03b5\u03c1\u03b7 \u03c4\u03b9\u03c4\u03bb\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ad\u03b3\u03c7\u03c5\u03c3\u03b7\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03c4\u03b7 LMWH, \u03b7 Anti-Xa \u03b4\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03b5 \u03cc\u03bb\u03bf\u03c5\u03c2. \u0396\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2: \u03ba\u03cd\u03b7\u03c3\u03b7 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03cc \u03b8\u03c1\u03bf\u03bc\u03b2\u03c9\u03c4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf, \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03b1\u03ba\u03c1\u03b1\u03af\u03bf \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2, \u03c0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2, \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5, \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03b9\u03ac\u03b6\u03bf\u03c5\u03c3\u03b1 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7 \u03c0\u03b1\u03c1\u03ac \u03b1\u03b3\u03c9\u03b3\u03ae \u03ae \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03b1\u03c6\u03ae \u03b5\u03be\u03ae\u03b3\u03b7\u03c3\u03b7.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u039a\u03cd\u03c1\u03b9\u03b5\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7:<\/strong><br \/>\n\u2022 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 UFH \u03cc\u03c4\u03b1\u03bd \u03c4\u03bf aPTT \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b1\u03be\u03b9\u03cc\u03c0\u03b9\u03c3\u03c4\u03bf \u03ae \u03b1\u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03bf<br \/>\n\u2022 LMWH \u03c3\u03b5 \u03ba\u03cd\u03b7\u03c3\u03b7, \u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1, \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2 \u03ae \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1<br \/>\n\u2022 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03ba\u03b1\u03b9 \u03bd\u03b5\u03bf\u03b3\u03bd\u03ac \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7<br \/>\n\u2022 \u03b2\u03b1\u03c1\u03ad\u03c9\u03c2 \u03c0\u03ac\u03c3\u03c7\u03bf\u03bd\u03c4\u03b5\u03c2, \u03b5\u03bd\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, ECMO \u03ae \u03bc\u03b7 \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c8\u03b9\u03bc\u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae<br \/>\n\u2022 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c5\u03c0\u03b5\u03c1\u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2, \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1\u03c2 \u03ae \u03c5\u03c0\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2<br \/>\n\u2022 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae\u03c2 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03bc\u03b5 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b6\u03b7\u03c4\u03b7\u03b8\u03b5\u03af \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03b3\u03cd\u03c1\u03c9 \u03b1\u03c0\u03cc \u03b5\u03c0\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2 \u03ae \u03c3\u03b5 \u03c0\u03b5\u03c1\u03b9\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03c7\u03b5\u03af\u03c1\u03b9\u03c3\u03b7, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03b1\u03c0\u03cc\u03c6\u03b1\u03c3\u03b7 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03ae\u03ba\u03b5\u03b9 \u03c3\u03c4\u03bf\u03bd \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03b1 \u03b9\u03b1\u03c4\u03c1\u03cc. \u0397 \u03b1\u03c0\u03bb\u03ae \u03c0\u03b5\u03c1\u03b9\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf \u00ab\u03c0\u03cc\u03c3\u03bf \u03b4\u03c5\u03bd\u03b1\u03c4\u03ae\u00bb \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b4\u03cc\u03c3\u03b7 \u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03b5\u03af. \u03a0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03cc\u03c2 \u03c7\u03c1\u03bf\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03c6\u03bb\u03b5\u03b2\u03b9\u03ba\u03ae\u03c2 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7\u03c2 \u03ae \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc, \u03b7 Anti-Xa \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/thromvofilia\/\">\u03b8\u03c1\u03bf\u03bc\u03b2\u03bf\u03c6\u03b9\u03bb\u03af\u03b1\u03c2<\/a>. \u0386\u03bb\u03bb\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03cc\u03c0\u03c9\u03c2 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/proteini-c-exetasi-aimatos-thromvofilia\/\">\u03a0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 C<\/a>, <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/protein-s-exetasi\/\">\u03a0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 S<\/a>, \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7, Factor V Leiden, \u03bc\u03b5\u03c4\u03ac\u03bb\u03bb\u03b1\u03be\u03b7 \u03c0\u03c1\u03bf\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03c4\u03b9\u03c6\u03c9\u03c3\u03c6\u03bf\u03bb\u03b9\u03c0\u03b9\u03b4\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1, \u03b1\u03c0\u03b1\u03bd\u03c4\u03bf\u03cd\u03bd \u03c3\u03b5 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03cc \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1: \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7, \u03cc\u03c7\u03b9 \u03c0\u03cc\u03c3\u03bf \u03b4\u03c1\u03b1 \u03b7 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03b5\u03ba\u03b5\u03af\u03bd\u03b7 \u03c4\u03b7 \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae.<\/p>\n<p><!-- ==================== SECTION 3 ==================== --><\/p>\n<h2 id=\"sec3\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">3<\/span><\/span>\u03a0\u03cc\u03c4\u03b5 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 \u03c3\u03c9\u03c3\u03c4\u03ae \u03ce\u03c1\u03b1 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03bf\u03c2 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03be\u03b9\u03bf\u03c0\u03b9\u03c3\u03c4\u03af\u03b1 \u03c4\u03b7\u03c2 Anti-Xa.<\/strong> \u0391\u03bd \u03c4\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03bb\u03b7\u03c6\u03b8\u03b5\u03af \u03c0\u03bf\u03bb\u03cd \u03bd\u03c9\u03c1\u03af\u03c2 \u03ae \u03c0\u03bf\u03bb\u03cd \u03b1\u03c1\u03b3\u03ac, \u03b7 \u03c4\u03b9\u03bc\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bb\u03b1\u03bd\u03b8\u03b1\u03c3\u03bc\u03ad\u03bd\u03b1 \u03c5\u03c8\u03b7\u03bb\u03ae \u03ae \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03bb\u03ac\u03b8\u03bf\u03c2 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03b4\u03cc\u03c3\u03b7\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0393\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03bf\u03cd \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b5\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03b7 enoxaparin, \u03b7 dalteparin \u03ae \u03b7 tinzaparin, \u03b7 \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03c4\u03bf <strong>peak<\/strong>, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 <strong>4 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03b4\u03cc\u03c1\u03b9\u03b1 \u03b4\u03cc\u03c3\u03b7<\/strong>. \u0391\u03c5\u03c4\u03cc \u03c4\u03bf \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c3\u03b7\u03bc\u03b5\u03af\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03c1\u03c5\u03c6\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03b5\u03b9 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c3\u03c4\u03cc\u03c7\u03bf\u03c5\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0393\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03ad\u03b2\u03b9\u03b1 UFH, \u03b7 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae. \u0397 UFH \u03c7\u03bf\u03c1\u03b7\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c9\u03c2 \u03c3\u03c5\u03bd\u03b5\u03c7\u03ae\u03c2 \u03ad\u03b3\u03c7\u03c5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b7 Anti-Xa \u03bc\u03b5\u03c4\u03c1\u03b9\u03ad\u03c4\u03b1\u03b9 \u03b1\u03c6\u03bf\u03cd \u03c0\u03b5\u03c1\u03ac\u03c3\u03b5\u03b9 \u03b1\u03c1\u03ba\u03b5\u03c4\u03cc\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c2 \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03ad\u03bd\u03b1\u03c1\u03be\u03b7 \u03ae \u03c4\u03b7\u03bd \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c1\u03c5\u03b8\u03bc\u03bf\u03cd. \u03a3\u03c5\u03c7\u03bd\u03ac \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b4\u03b9\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 <strong>4\u20136 \u03c9\u03c1\u03ce\u03bd<\/strong> \u03ae \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf \u03c4\u03bf\u03c5 \u03bd\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf\u03c5.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u03a7\u03c1\u03bf\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b1\u03bd\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf:<\/strong><br \/>\n\u2022 LMWH: \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 4 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03b4\u03cc\u03c1\u03b9\u03b1 \u03b4\u03cc\u03c3\u03b7<br \/>\n\u2022 UFH \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03ad\u03b2\u03b9\u03b1: \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ad\u03b3\u03c7\u03c5\u03c3\u03b7\u03c2 \u03ae \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c1\u03c5\u03b8\u03bc\u03bf\u03cd, \u03c3\u03c5\u03c7\u03bd\u03ac 4\u20136 \u03ce\u03c1\u03b5\u03c2<br \/>\n\u2022 Fondaparinux: \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 3 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7, \u03bc\u03b5 fondaparinux-calibrated \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf<br \/>\n\u2022 DOACs: \u03b4\u03b5\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b7 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ae Anti-Xa \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03b3\u03b9\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 \u03ce\u03c1\u03b1 \u03c4\u03b7\u03c2 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b3\u03c1\u03ac\u03c6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03c4\u03bf \u03c0\u03b1\u03c1\u03b1\u03c0\u03b5\u03bc\u03c0\u03c4\u03b9\u03ba\u03cc \u03ae \u03bd\u03b1 \u03b4\u03b7\u03bb\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf. \u03a4\u03bf \u03af\u03b4\u03b9\u03bf \u03b9\u03c3\u03c7\u03cd\u03b5\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03b1\u03ba\u03c1\u03b9\u03b2\u03ad\u03c2 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf, \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7, \u03c4\u03b7 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7. \u0388\u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 Anti-Xa \u03c7\u03c9\u03c1\u03af\u03c2 \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b4\u03cd\u03c3\u03ba\u03bf\u03bb\u03bf \u03ae \u03b1\u03b4\u03cd\u03bd\u03b1\u03c4\u03bf \u03bd\u03b1 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03c5\u03c4\u03b5\u03af \u03c3\u03c9\u03c3\u03c4\u03ac.<\/p>\n<div style=\"background: #fff7ed; border-left: 4px solid #ea580c; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u03a0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac:<\/strong> \u0391\u03bd \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03ba\u03ac\u03bd\u03b5\u03b9 LMWH \u03c3\u03c4\u03b9\u03c2 08:00, \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03b3\u03b9\u03b1 peak Anti-Xa \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u03c3\u03c4\u03b9\u03c2 12:00. \u0391\u03bd \u03b7 \u03bb\u03ae\u03c8\u03b7 \u03b3\u03af\u03bd\u03b5\u03b9 \u03c3\u03c4\u03b9\u03c2 09:00 \u03ae \u03c3\u03c4\u03b9\u03c2 16:00, \u03b7 \u03c4\u03b9\u03bc\u03ae \u03b4\u03b5\u03bd \u03c3\u03c5\u03b3\u03ba\u03c1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03af\u03b4\u03b9\u03bf\u03c5\u03c2 \u03c3\u03c4\u03cc\u03c7\u03bf\u03c5\u03c2.<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03b5 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03c4\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2, \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03af\u03b4\u03b9\u03bf \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c3\u03b7\u03bc\u03b5\u03af\u03bf \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7. \u0394\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac, \u03bc\u03b9\u03b1 \u03c6\u03b1\u03b9\u03bd\u03bf\u03bc\u03b5\u03bd\u03b9\u03ba\u03ae \u00ab\u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ae\u00bb \u03c4\u03b7\u03c2 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bd\u03c4\u03b1\u03bd\u03b1\u03ba\u03bb\u03ac \u03bc\u03cc\u03bd\u03bf \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03cc timing \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c3\u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2.<\/p>\n<p><!-- ==================== SECTION 4 ==================== --><\/p>\n<h2 id=\"sec4\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">4<\/span><\/span>\u03a4\u03b9\u03bc\u03ad\u03c2 Anti-Xa \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03bf\u03af \u03c3\u03c4\u03cc\u03c7\u03bf\u03b9<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u039f\u03b9 \u03c4\u03b9\u03bc\u03ad\u03c2 Anti-Xa \u03b5\u03ba\u03c6\u03c1\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03b5 IU\/mL, \u03b1\u03bb\u03bb\u03ac \u03bf\u03b9 \u03c3\u03c4\u03cc\u03c7\u03bf\u03b9 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03af\u03b4\u03b9\u03bf\u03b9 \u03b3\u03b9\u03b1 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03ba\u03b1\u03b9 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03c3\u03c7\u03ae\u03bc\u03b1\u03c4\u03b1.<\/strong> \u0397 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03bf \u03b5\u03af\u03b4\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2, \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7, \u03c4\u03bf\u03bd \u03c7\u03c1\u03cc\u03bd\u03bf \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2, \u03c4\u03b7\u03bd \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03cc\u03c1\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03bf\u03c5.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u039f\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ba\u03ac\u03c4\u03c9 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bc\u03b5\u03bd\u03b1 \u03b5\u03cd\u03c1\u03b7 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03b1\u03c0\u03cc\u03bb\u03c5\u03c4\u03bf\u03b9 \u03ba\u03b1\u03bd\u03cc\u03bd\u03b5\u03c2. \u0394\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03b1\u03bd\u03c4\u03b9\u03b4\u03c1\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf, \u03c4\u03bf \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf, \u03c4\u03b7\u03bd \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b1\u03bd \u03b7 \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \u03b1\u03c6\u03bf\u03c1\u03ac peak \u03ae steady-state. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03b7 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03b1 \u03b9\u03b1\u03c4\u03c1\u03cc \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03c0\u03bf\u03c5 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\">\u2194\ufe0f \u03a3\u03cd\u03c1\u03b5\u03c4\u03b5 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03c4\u03ae\u03bb\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03af\u03bd\u03b1\u03ba\u03b1<\/div>\n<div style=\"overflow-x: auto; margin: 10px 0 16px;\">\n<table style=\"width: 100%; border-collapse: collapse; min-width: 720px; color: #111827; font-size: 14px;\">\n<thead style=\"background: #f3f4f6;\">\n<tr>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">\u0391\u03b3\u03c9\u03b3\u03ae \/ \u03c3\u03c7\u03ae\u03bc\u03b1<\/th>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">\u03a3\u03c9\u03c3\u03c4\u03cc\u03c2 \u03c7\u03c1\u03bf\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2<\/th>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">\u03a3\u03c5\u03bd\u03ae\u03b8\u03b7\u03c2 \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 Anti-Xa<\/th>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">\u03a3\u03c7\u03cc\u03bb\u03b9\u03bf<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">UFH \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03ad\u03b2\u03b9\u03b1<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u039c\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03ad\u03b3\u03c7\u03c5\u03c3\u03b7\u03c2 \u03ae \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae\u03c2 \u03c1\u03c5\u03b8\u03bc\u03bf\u03cd<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">0.3\u20130.7 IU\/mL<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a3\u03c5\u03c7\u03bd\u03cc \u03b5\u03cd\u03c1\u03bf\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 UFH, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">LMWH \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae BID<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">Peak \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 4 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">0.5\u20131.0 IU\/mL<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a3\u03c5\u03c7\u03bd\u03ac \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b4\u03cc\u03c3\u03b7 \u03b4\u03cd\u03bf \u03c6\u03bf\u03c1\u03ad\u03c2 \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">LMWH \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae QD<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">Peak \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 4 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">1.0\u20132.0 IU\/mL<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0393\u03b9\u03b1 \u03c3\u03c7\u03ae\u03bc\u03b1\u03c4\u03b1 \u03ac\u03c0\u03b1\u03be \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2, \u03bc\u03b5 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03c3\u03c4\u03b7\u03bd \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">LMWH \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">Peak \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 4 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 0.2\u20130.5 IU\/mL<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a4\u03b1 \u03cc\u03c1\u03b9\u03b1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03cc\u03c3\u03bf \u03b1\u03c5\u03c3\u03c4\u03b7\u03c1\u03ac \u03c4\u03c5\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b1 \u03cc\u03c3\u03bf \u03c3\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b4\u03cc\u03c3\u03b7<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">Fondaparinux<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">Peak \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 3 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03b2\u03b1\u03b8\u03bc\u03bf\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0391\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 calibrated \u03b3\u03b9\u03b1 fondaparinux, \u03cc\u03c7\u03b9 \u03b1\u03c0\u03bb\u03ae Anti-Xa \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u039c\u03b9\u03b1 \u03c0\u03bf\u03bb\u03cd \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03c4\u03b9\u03bc\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03c5\u03c0\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03bb\u03ac\u03b8\u03bf\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2, \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7, \u03b1\u03bd\u03b5\u03c0\u03b1\u03c1\u03ba\u03ae \u03b1\u03c0\u03bf\u03c1\u03c1\u03cc\u03c6\u03b7\u03c3\u03b7 \u03ae \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1. \u039c\u03b9\u03b1 \u03c5\u03c8\u03b7\u03bb\u03ae \u03c4\u03b9\u03bc\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7 LMWH, \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7 \u03c0\u03b9\u03bf \u03ba\u03bf\u03bd\u03c4\u03ac \u03b1\u03c0\u03cc \u03c4\u03bf \u03b1\u03bd\u03b1\u03bc\u03b5\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf \u03ae \u03b5\u03c0\u03b9\u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u03a0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c1\u03b9\u03b8\u03bc\u03ce\u03bd:<\/strong><br \/>\n\u2022 Anti-Xa 0.1 IU\/mL: \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03b3\u03b9\u03b1 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae, \u03b1\u03bb\u03bb\u03ac \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc timing \u03ba\u03b1\u03b9 \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7<br \/>\n\u2022 Anti-Xa 0.3 IU\/mL: \u03ba\u03b1\u03c4\u03ce\u03c4\u03b5\u03c1\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03cc\u03c1\u03b9\u03bf \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ac UFH \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03b1<br \/>\n\u2022 Anti-Xa 0.8 IU\/mL: \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd \u03b5\u03cd\u03c1\u03bf\u03c5\u03c2 \u03b3\u03b9\u03b1 LMWH BID, \u03b1\u03bb\u03bb\u03ac \u03cc\u03c7\u03b9 \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03c3\u03c7\u03ae\u03bc\u03b1<br \/>\n\u2022 Anti-Xa \u22651.5 IU\/mL: \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c8\u03b7\u03bb\u03ae, \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03c3\u03b5 BID \u03c3\u03c7\u03ae\u03bc\u03b1 \u03ae \u03c3\u03b5 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 Anti-Xa \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c0\u03c9\u03c2 \u03bc\u03b9\u03b1 \u03b1\u03c0\u03bb\u03ae \u03b2\u03b9\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03bc\u03b5 \u03ad\u03bd\u03b1 \u03b3\u03b5\u03bd\u03b9\u03ba\u03cc \u00ab\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc\u00bb \u03cc\u03c1\u03b9\u03bf. \u0394\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03af\u03b1 \u03c4\u03b9\u03bc\u03ae \u03c0\u03bf\u03c5 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b3\u03b9\u03b1 \u03cc\u03bb\u03bf\u03c5\u03c2. \u0397 \u03af\u03b4\u03b9\u03b1 \u03c4\u03b9\u03bc\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03b9\u03b8\u03c5\u03bc\u03b7\u03c4\u03ae \u03c3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b2\u03bb\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03b5 \u03ac\u03bb\u03bb\u03bf\u03bd, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf, \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7, \u03ce\u03c1\u03b1 \u03bb\u03ae\u03c8\u03b7\u03c2, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1\u03c2.<\/p>\n<p><!-- ==================== SECTION 5 ==================== --><\/p>\n<h2 id=\"sec5\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">5<\/span><\/span>UFH, LMWH \u03ba\u03b1\u03b9 fondaparinux<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 Anti-Xa \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03bd\u03cc\u03b7\u03bc\u03b1 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9.<\/strong> \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03b9 \u03b1\u03bd \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 UFH, LMWH, fondaparinux \u03ae \u03ac\u03bc\u03b5\u03c3\u03bf \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03b1 Xa \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 <strong>UFH<\/strong> \u03ad\u03c7\u03b5\u03b9 \u03c0\u03b9\u03bf \u03b1\u03c0\u03c1\u03cc\u03b2\u03bb\u03b5\u03c0\u03c4\u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae. \u03a3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b7 \u03b3\u03c1\u03b1\u03bc\u03bc\u03b9\u03ba\u03ae \u03c3\u03c7\u03ad\u03c3\u03b7 \u03b4\u03cc\u03c3\u03b7\u03c2-\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03ad\u03b2\u03b9\u03b1 \u03c4\u03b9\u03c4\u03bb\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7. \u03a0\u03b1\u03c1\u03b1\u03b4\u03bf\u03c3\u03b9\u03b1\u03ba\u03ac \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5 aPTT, \u03b1\u03bb\u03bb\u03ac \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ac \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1 \u03b7 Anti-Xa \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c0\u03b9\u03bf \u03ac\u03bc\u03b5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b5\u03c5\u03ac\u03bb\u03c9\u03c4\u03b7 \u03c3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03bf\u03bb\u03ad\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u039f\u03b9 <strong>LMWH<\/strong> \u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03b9\u03bf \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c8\u03b9\u03bc\u03b7 \u03b1\u03c0\u03bf\u03c1\u03c1\u03cc\u03c6\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b2\u03b9\u03bf\u03b4\u03b9\u03b1\u03b8\u03b5\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03c5\u03c0\u03bf\u03b4\u03cc\u03c1\u03b9\u03b1 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf\u03c5\u03c2 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03bf\u03cd\u03c2 \u03b5\u03bd\u03ae\u03bb\u03b9\u03ba\u03b5\u03c2. \u038c\u03c4\u03b1\u03bd \u03cc\u03bc\u03c9\u03c2 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ba\u03cd\u03b7\u03c3\u03b7, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03c0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03ae \u03b1\u03ba\u03c1\u03b1\u03af\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2, \u03b7 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03af\u03ba\u03b5\u03c5\u03c3\u03b7.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a4\u03bf <strong>fondaparinux<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03b5\u03bd\u03c4\u03b1\u03c3\u03b1\u03ba\u03c7\u03b1\u03c1\u03af\u03c4\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03c3\u03c4\u03ad\u03bb\u03bb\u03b5\u03b9 \u03b5\u03ba\u03bb\u03b5\u03ba\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03bd \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 Xa \u03bc\u03ad\u03c3\u03c9 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2. \u0394\u03b5\u03bd \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5 aPTT \u03ae INR. \u0391\u03bd \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7, \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 anti-Xa assay \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b2\u03b1\u03b8\u03bc\u03bf\u03bd\u03bf\u03bc\u03b7\u03bc\u03ad\u03bd\u03bf \u03b3\u03b9\u03b1 fondaparinux. \u0397 \u03b1\u03c0\u03bb\u03ae \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac \u00abAnti-Xa\u00bb \u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03b5\u03af.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\">\u2194\ufe0f \u03a3\u03cd\u03c1\u03b5\u03c4\u03b5 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03c4\u03ae\u03bb\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03af\u03bd\u03b1\u03ba\u03b1<\/div>\n<div style=\"overflow-x: auto; margin: 10px 0 16px;\">\n<table style=\"width: 100%; border-collapse: collapse; min-width: 760px; color: #111827; font-size: 14px;\">\n<thead style=\"background: #f3f4f6;\">\n<tr>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">\u03a0\u03b1\u03c1\u03ac\u03bc\u03b5\u03c4\u03c1\u03bf\u03c2<\/th>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">UFH<\/th>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">LMWH<\/th>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">Fondaparinux<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a4\u03c1\u03cc\u03c0\u03bf\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 IV \u03ad\u03b3\u03c7\u03c5\u03c3\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a5\u03c0\u03bf\u03b4\u03cc\u03c1\u03b9\u03b1<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a5\u03c0\u03bf\u03b4\u03cc\u03c1\u03b9\u03b1<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">aPTT \u03ae Anti-Xa<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">Anti-Xa \u03bc\u03cc\u03bd\u03bf \u03c3\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a3\u03c0\u03ac\u03bd\u03b9\u03b1, \u03bc\u03cc\u03bd\u03bf \u03bc\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03b2\u03b1\u03b8\u03bc\u03bf\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u039d\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b5\u03be\u03b1\u03c1\u03c4\u03ce\u03bc\u03b5\u03bd\u03b7 \u03b1\u03c0\u03cc \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03ba\u03ac\u03b8\u03b1\u03c1\u03c3\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7 \u03c3\u03b5 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc eGFR<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03c3\u03b5 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0391\u03bd\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a0\u03c1\u03c9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7 \u03bc\u03b5 \u03ba\u03b1\u03bb\u03ae \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u03a0\u03c1\u03c9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7 \u03bc\u03b5\u03c1\u03b9\u03ba\u03ce\u03c2 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0394\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b1\u03c0\u03bb\u03cc \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03b1\u03bd\u03c4\u03af\u03b4\u03bf\u03c4\u03bf \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae\u03c2 \u03c7\u03c1\u03ae\u03c3\u03b7\u03c2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03bb\u03ac\u03b8\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1 \u03c3\u03c5\u03b3\u03ba\u03c1\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c4\u03b9\u03bc\u03ad\u03c2 Anti-Xa \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ce\u03bd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c3\u03b1\u03bd \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03c3\u03bf\u03b4\u03cd\u03bd\u03b1\u03bc\u03b5\u03c2. \u0388\u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 LMWH \u03b4\u03b5\u03bd \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c0\u03c9\u03c2 \u03ad\u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 UFH. \u03a4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b7 \u03b2\u03b1\u03b8\u03bc\u03bf\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bf \u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf.<\/p>\n<p><!-- ==================== SECTION 6 ==================== --><\/p>\n<h2 id=\"sec6\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">6<\/span><\/span>\u03a0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 Anti-Xa \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf, \u03c4\u03bf timing, \u03c4\u03b7 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03c4\u03bf \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2, \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf-\u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2.<\/strong> \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03b7 \u03c4\u03b9\u03bc\u03ae \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03b2\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03bf\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b1.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 <strong>\u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b7 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b3\u03b9\u03b1 LMWH \u03ba\u03b1\u03b9 fondaparinux. \u038c\u03c4\u03b1\u03bd \u03c4\u03bf eGFR \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc, \u03b7 \u03ba\u03ac\u03b8\u03b1\u03c1\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03b9\u03c9\u03b8\u03b5\u03af \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf, \u03b7\u03bb\u03b9\u03ba\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03ae \u03bf\u03be\u03b5\u03af\u03b1 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7, \u03b7 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/kreatinini-aimatos-ouron\/\">\u03ba\u03c1\u03b5\u03b1\u03c4\u03b9\u03bd\u03af\u03bd\u03b7<\/a> \u03ba\u03b1\u03b9 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/egfr\/\">eGFR<\/a> \u03b3\u03b9\u03b1 \u03b1\u03c3\u03c6\u03b1\u03bb\u03ad\u03c3\u03c4\u03b5\u03c1\u03b7 \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a4\u03bf <strong>\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2<\/strong> \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf\u03bd \u03cc\u03b3\u03ba\u03bf \u03ba\u03b1\u03c4\u03b1\u03bd\u03bf\u03bc\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1. \u03a3\u03b5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1, \u03bf\u03b9 fixed \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03bf\u03c5\u03bd \u03c3\u03b5 \u03c5\u03c0\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03b5\u03bd\u03ce \u03c3\u03b5 \u03c0\u03bf\u03bb\u03cd \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c3\u03c5\u03b3\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2. \u0397 Anti-Xa \u03b4\u03b5\u03bd \u03b4\u03af\u03bd\u03b5\u03b9 \u03b1\u03c5\u03c4\u03cc\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7, \u03b1\u03bb\u03bb\u03ac \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03b1\u03bd \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 \u03b5\u03c0\u03b9\u03b8\u03c5\u03bc\u03b7\u03c4\u03bf\u03cd \u03c3\u03c4\u03cc\u03c7\u03bf\u03c5.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 <strong>\u03ba\u03cd\u03b7\u03c3\u03b7<\/strong> \u03bc\u03b5\u03c4\u03b1\u03b2\u03ac\u03bb\u03bb\u03b5\u03b9 \u03c4\u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 LMWH. \u0391\u03c5\u03be\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bf \u03cc\u03b3\u03ba\u03bf\u03c2 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03b7 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03ba\u03ac\u03b8\u03b1\u03c1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03ac\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03b4\u03c5\u03bd\u03b1\u03bc\u03b9\u03ba\u03ac. \u03a0\u03b1\u03c1\u03cc\u03c4\u03b9 \u03b7 \u03c1\u03bf\u03c5\u03c4\u03af\u03bd\u03b1 monitoring \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b7 \u03c3\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03b5\u03b3\u03ba\u03cd\u03bf\u03c5\u03c2, \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c5\u03c8\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03b7 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03c9\u03c2 \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03bf \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03af\u03ba\u03b5\u03c5\u03c3\u03b7\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 <strong>\u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2. \u03a3\u03b5 \u03b2\u03b1\u03c1\u03b9\u03ac \u03bd\u03cc\u03c3\u03bf, \u03c3\u03ae\u03c8\u03b7, ECMO, \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf, \u03ba\u03b1\u03c4\u03b1\u03bd\u03ac\u03bb\u03c9\u03c3\u03b7 \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03ae \u03c3\u03c5\u03b3\u03b3\u03b5\u03bd\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1, \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03ae\u03c3\u03b5\u03b9 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7\u03c2. \u03a3\u03b5 \u03c4\u03ad\u03c4\u03bf\u03b9\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03bf \u03c0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03bf\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c4\u03c5\u03c6\u03bb\u03ae \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u03a0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9:<\/strong><br \/>\n\u2022 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ad\u03c2 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf: UFH, LMWH, fondaparinux \u03ae DOAC<br \/>\n\u2022 \u03b4\u03cc\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03ce\u03c1\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2<br \/>\n\u2022 \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7: \u03c0\u03c1\u03bf\u03c6\u03cd\u03bb\u03b1\u03be\u03b7 \u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1<br \/>\n\u2022 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ae eGFR<br \/>\n\u2022 \u03ba\u03cd\u03b7\u03c3\u03b7, \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2, \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1 \u03ae \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7<br \/>\n\u2022 \u03bb\u03ae\u03c8\u03b7 rivaroxaban, apixaban, edoxaban \u03ae \u03ac\u03bb\u03bb\u03bf\u03c5 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03b1 Xa<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a0\u03c1\u03bf-\u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03ac \u03c3\u03c6\u03ac\u03bb\u03bc\u03b1\u03c4\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03bb\u03ae\u03c8\u03b7 \u03b1\u03c0\u03cc \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae \u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03b7\u03c0\u03b1\u03c1\u03b9\u03bd\u03b9\u03c3\u03c4\u03b5\u03af, \u03bb\u03ac\u03b8\u03bf\u03c2 \u03c0\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7 \u03c3\u03c9\u03bb\u03ae\u03bd\u03b1 \u03ba\u03b9\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd, \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7 \u03c6\u03c5\u03b3\u03bf\u03ba\u03ad\u03bd\u03c4\u03c1\u03b7\u03c3\u03b7\u03c2 \u03ae \u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7, \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b1\u03bb\u03bb\u03bf\u03b9\u03ce\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1. \u03a0\u03c1\u03b9\u03bd \u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9 \u03b7 \u03b4\u03cc\u03c3\u03b7, \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03c4\u03b9\u03bc\u03ae \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c3\u03c9\u03c3\u03c4\u03ac \u03bb\u03b7\u03c6\u03b8\u03ad\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ac \u03c7\u03c1\u03bf\u03bd\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1.<\/p>\n<p><!-- ==================== SECTION 7 ==================== --><\/p>\n<h2 id=\"sec7\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">7<\/span><\/span>\u0395\u03b9\u03b4\u03b9\u03ba\u03bf\u03af \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03bf\u03af \u03ba\u03b1\u03b9 \u03ba\u03cd\u03b7\u03c3\u03b7<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 Anti-Xa \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1 \u03c3\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03bf\u03cd\u03c2, \u03cc\u03c0\u03bf\u03c5 \u03b7 \u03c4\u03c5\u03c0\u03b9\u03ba\u03ae \u03b4\u03cc\u03c3\u03b7 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03b4\u03b5\u03bd \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c0\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bc\u03b5 \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7.<\/strong> \u03a3\u03b5 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b4\u03b5\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03ba\u03ac, \u03b1\u03bb\u03bb\u03ac \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03be\u03b5\u03b9 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b1\u03c0\u03bf\u03c6\u03ac\u03c3\u03b5\u03b9\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03c4\u03b7\u03bd <strong>\u03ba\u03cd\u03b7\u03c3\u03b7<\/strong>, \u03b7 LMWH \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c2 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03c6\u03bb\u03b5\u03b2\u03b9\u03ba\u03ae\u03c2 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7\u03c2, \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc VTE, \u03b1\u03bd\u03c4\u03b9\u03c6\u03c9\u03c3\u03c6\u03bf\u03bb\u03b9\u03c0\u03b9\u03b4\u03b9\u03ba\u03cc \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf, \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b2\u03b1\u03bb\u03b2\u03af\u03b4\u03b5\u03c2 \u03ae \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b1\u03b9\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2. \u0397 Anti-Xa \u03b4\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03b5\u03b3\u03ba\u03cd\u03bf\u03c5\u03c2 \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae. \u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03cc\u03bc\u03c9\u03c2 \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af \u03cc\u03c4\u03b1\u03bd \u03b7 \u03b4\u03cc\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae, \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b1\u03ba\u03c1\u03b1\u03af\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03b9\u03ac\u03b6\u03bf\u03bd \u03b5\u03c0\u03b5\u03b9\u03c3\u03cc\u03b4\u03b9\u03bf \u03ae \u03cc\u03c4\u03b1\u03bd \u03bf \u03b8\u03b5\u03c1\u03ac\u03c0\u03c9\u03bd \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/antifosfolipidiko-syndromo\/\">\u03b1\u03bd\u03c4\u03b9\u03c6\u03c9\u03c3\u03c6\u03bf\u03bb\u03b9\u03c0\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5<\/a>, \u03b7 Anti-Xa \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2 APS. \u0397 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03ba\u03c1\u03b9\u03c4\u03ae\u03c1\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03cc\u03c0\u03c9\u03c2 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/lupus-anticoagulant-la\/\">Lupus Anticoagulant<\/a>, \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03bb\u03b9\u03c0\u03b9\u03bd\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 anti-\u03b22GPI. \u0397 Anti-Xa \u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03cc\u03c4\u03b1\u03bd \u03b7 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03ae\u03b4\u03b7 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03b5\u03af \u03c9\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u039a\u03cd\u03b7\u03c3\u03b7 \u2013 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c7\u03c1\u03ae\u03c3\u03b7:<\/strong><br \/>\n\u2022 \u03b4\u03b5\u03bd \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c5\u03c4\u03cc\u03bc\u03b1\u03c4\u03b1 \u03c3\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae LMWH<br \/>\n\u2022 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1 \u03c3\u03b5 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b4\u03cc\u03c3\u03b7, \u03c5\u03c8\u03b7\u03bb\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ae \u03bc\u03b7 \u03c0\u03c1\u03bf\u03b2\u03bb\u03ad\u03c8\u03b9\u03bc\u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae<br \/>\n\u2022 \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf peak, \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 4 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7<br \/>\n\u2022 \u03b7 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03b4\u03cc\u03c3\u03b7\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03b1, \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03c4\u03bf\u03c5\u03c2 <strong>\u03b7\u03bb\u03b9\u03ba\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2<\/strong>, \u03b7 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03ae \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03b9\u03ba\u03cc\u03c2 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2. \u0397 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03ba\u03c1\u03b5\u03b1\u03c4\u03b9\u03bd\u03af\u03bd\u03b7 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc eGFR, \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03cc\u03c4\u03b1\u03bd \u03b7 \u03bc\u03c5\u03ca\u03ba\u03ae \u03bc\u03ac\u03b6\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7. \u03a3\u03b5 \u03b1\u03bc\u03c6\u03af\u03b2\u03bf\u03bb\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2, \u03bf \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bd\u03b9\u03c3\u03c7\u03c5\u03b8\u03b5\u03af \u03bc\u03b5 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03b7 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/cystatin-c\/\">\u03ba\u03c5\u03c3\u03c4\u03b1\u03c4\u03af\u03bd\u03b7 C<\/a>, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03c4\u03b1 <strong>\u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03ba\u03b1\u03b9 \u03bd\u03b5\u03bf\u03b3\u03bd\u03ac<\/strong>, \u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03b1\u03c0\u03cc \u03c4\u03c9\u03bd \u03b5\u03bd\u03b7\u03bb\u03af\u03ba\u03c9\u03bd. \u03a4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac, \u03bf \u03cc\u03b3\u03ba\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03bd\u03bf\u03bc\u03ae\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03ac\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03b7 Anti-Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03c3\u03c5\u03c7\u03bd\u03ac \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03c3\u03b5 \u03c0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ac \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ac \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03b1.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03b5 <strong>\u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1<\/strong>, \u03b7 \u03b4\u03cc\u03c3\u03b7 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03bf \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2, \u03c4\u03bf \u03b9\u03b4\u03b1\u03bd\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2 \u03ae \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03c3\u03bc\u03ad\u03bd\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf. \u0397 Anti-Xa \u03b4\u03b5\u03bd \u03b5\u03c0\u03b9\u03bb\u03cd\u03b5\u03b9 \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03b7 \u03c4\u03b7\u03c2 \u03c4\u03b7 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03b1\u03bd \u03b7 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03c4\u03c5\u03b3\u03c7\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03b5\u03c0\u03b9\u03b8\u03c5\u03bc\u03b7\u03c4\u03cc \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c3\u03c4\u03cc\u03c7\u03bf.<\/p>\n<p><!-- ==================== SECTION 8 ==================== --><\/p>\n<h2 id=\"sec8\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">8<\/span><\/span>\u03a0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf-\u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 Anti-Xa \u03b4\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03b1\u03c5\u03c3\u03c4\u03b7\u03c1\u03cc \u03c0\u03c1\u03bf-\u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf.<\/strong> \u0397 \u03c3\u03c9\u03c3\u03c4\u03ae \u03c0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03b4\u03b5\u03bd \u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03bf \u03c6\u03b1\u03b3\u03b7\u03c4\u03cc, \u03b1\u03bb\u03bb\u03ac \u03c4\u03b7\u03bd \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03b5\u03b9 \u03c4\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ae \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u039f \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03bd\u03b7\u03bc\u03b5\u03c1\u03ce\u03c3\u03b5\u03b9 \u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03b3\u03b9\u03b1 \u03c4\u03bf \u03b1\u03ba\u03c1\u03b9\u03b2\u03ad\u03c2 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9. \u0397 \u03bb\u03ad\u03be\u03b7 \u00ab\u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u00bb \u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03b5\u03af. \u03a0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b1\u03c6\u03ad\u03c2 \u03b1\u03bd \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 UFH, LMWH, fondaparinux \u03ae \u03ac\u03bb\u03bb\u03bf \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03cc. \u03a0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b4\u03cc\u03c3\u03b7, \u03b7 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1, \u03b7 \u03ce\u03c1\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03bf \u03bb\u03cc\u03b3\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03b6\u03b7\u03c4\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a4\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03b5 \u03c3\u03c9\u03bb\u03ae\u03bd\u03b1 \u03ba\u03b9\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd \u03bd\u03b1\u03c4\u03c1\u03af\u03bf\u03c5 3.2%, \u03bc\u03b5 \u03c3\u03c9\u03c3\u03c4\u03ae \u03c0\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7. \u0397 \u03b1\u03bd\u03b1\u03bb\u03bf\u03b3\u03af\u03b1 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03c1\u03bf\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae. \u0391\u03bd \u03bf \u03c3\u03c9\u03bb\u03ae\u03bd\u03b1\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03bf\u03b3\u03b5\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ae \u03c5\u03c0\u03b5\u03c1\u03b3\u03b5\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c2, \u03b7 \u03b1\u03bd\u03b1\u03bb\u03bf\u03b3\u03af\u03b1 \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03b1\u03c3\u03c4\u03b5\u03af. \u03a3\u03b5 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03ba\u03c1\u03af\u03c4\u03b7 \u03c0\u03ac\u03bd\u03c9 \u03b1\u03c0\u03cc 55% \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af \u03b4\u03b9\u03cc\u03c1\u03b8\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5 \u03ba\u03b9\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u03a0\u03c1\u03bf-\u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03ae checklist:<\/strong><br \/>\n\u2022 \u03c3\u03c9\u03c3\u03c4\u03cc\u03c2 \u03c3\u03c9\u03bb\u03ae\u03bd\u03b1\u03c2 \u03ba\u03b9\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd 3.2% \u03ba\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ae \u03c0\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7<br \/>\n\u2022 \u03b1\u03bd\u03b1\u03b3\u03c1\u03b1\u03c6\u03ae \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5, \u03b4\u03cc\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ce\u03c1\u03b1\u03c2 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2<br \/>\n\u2022 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03c3\u03c4\u03bf \u03c3\u03c9\u03c3\u03c4\u03cc peak \u03ae steady-state<br \/>\n\u2022 \u03b1\u03c0\u03bf\u03c6\u03c5\u03b3\u03ae \u03bb\u03ae\u03c8\u03b7\u03c2 \u03b1\u03c0\u03cc \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b7\u03c0\u03b1\u03c1\u03b9\u03bd\u03b9\u03c3\u03c4\u03b5\u03af<br \/>\n\u2022 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03c6\u03c5\u03b3\u03bf\u03ba\u03ad\u03bd\u03c4\u03c1\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c7\u03c9\u03c1\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03cc\u03c4\u03b1\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9<br \/>\n\u2022 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7 \u03b3\u03b9\u03b1 DOACs, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03ba\u03cd\u03b7\u03c3\u03b7 \u03ae \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b9\u03c2 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b5\u03c2 \u03b1\u03c0\u03cc \u03c6\u03bb\u03b5\u03b2\u03b9\u03ba\u03ad\u03c2 \u03ae \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03ad\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2. \u0391\u03bd \u03b7 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae \u03ad\u03c7\u03b5\u03b9 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03b3\u03b9\u03b1 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03ae \u03ad\u03c7\u03b5\u03b9 \u03b5\u03ba\u03c0\u03bb\u03c5\u03b8\u03b5\u03af \u03bc\u03b5 \u03b7\u03c0\u03b1\u03c1\u03b9\u03bd\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b4\u03b9\u03ac\u03bb\u03c5\u03bc\u03b1, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c5\u03c0\u03ac\u03c1\u03be\u03b5\u03b9 \u03b5\u03c0\u03b9\u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b5\u03c7\u03bd\u03b7\u03c4\u03ac \u03c5\u03c8\u03b7\u03bb\u03ae Anti-Xa. \u038c\u03c4\u03b1\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03bd, \u03c0\u03c1\u03bf\u03c4\u03b9\u03bc\u03ac\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c6\u03b5\u03c1\u03b9\u03ba\u03ae \u03c6\u03bb\u03b5\u03b2\u03bf\u03ba\u03ad\u03bd\u03c4\u03b7\u03c3\u03b7.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b5\u03c2 \u03b1\u03b9\u03bc\u03cc\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c6\u03c4\u03ac\u03bd\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf \u03c4\u03bf\u03c5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03bf\u03c5. \u03a3\u03b5 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u03c0\u03c1\u03bf\u03c2 \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf, \u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af \u03b4\u03b9\u03b1\u03c7\u03c9\u03c1\u03b9\u03c3\u03bc\u03cc \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03c8\u03c5\u03be\u03b7, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf.<\/p>\n<div style=\"background: #fff7ed; border-left: 4px solid #ea580c; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u03a0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac:<\/strong> \u0397 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 Anti-Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03c4\u03ae \u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ae \u03ce\u03c1\u03b1, \u03c3\u03c9\u03c3\u03c4\u03cc \u03c3\u03c9\u03bb\u03ae\u03bd\u03b1, \u03c3\u03c9\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1. \u03a7\u03c9\u03c1\u03af\u03c2 \u03b1\u03c5\u03c4\u03ac, \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ae\u03c2 \u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03ae\u03c2 \u03b4\u03af\u03bd\u03b5\u03b9 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b1\u03be\u03af\u03b1\u03c2.<\/div>\n<p><!-- ==================== SECTION 9 ==================== --><\/p>\n<h2 id=\"sec9\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">9<\/span><\/span>Anti-Xa vs aPTT, INR \u03ba\u03b1\u03b9 calibrated assays<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 Anti-Xa, \u03c4\u03bf aPTT \u03ba\u03b1\u03b9 \u03c4\u03bf INR \u03b4\u03b5\u03bd \u03bc\u03b5\u03c4\u03c1\u03bf\u03cd\u03bd \u03c4\u03bf \u03af\u03b4\u03b9\u03bf \u03c0\u03c1\u03ac\u03b3\u03bc\u03b1.<\/strong> \u0397 \u03c3\u03cd\u03b3\u03c7\u03c5\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03bf\u03c5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ae \u03b1\u03b9\u03c4\u03af\u03b1 \u03bb\u03b1\u03bd\u03b8\u03b1\u03c3\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1\u03c2, \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ac.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a4\u03bf <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/aptt-exetasi-aimatos\/\">aPTT<\/a> \u03b5\u03ba\u03c4\u03b9\u03bc\u03ac \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae \u03ba\u03b1\u03b9 \u03ba\u03bf\u03b9\u03bd\u03ae \u03bf\u03b4\u03cc \u03c0\u03ae\u03be\u03b7\u03c2. \u03a7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03b4\u03bf\u03c3\u03b9\u03b1\u03ba\u03ac \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 UFH, \u03b1\u03bb\u03bb\u03ac \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c0\u03bf\u03bb\u03bb\u03bf\u03cd\u03c2 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2. \u03a3\u03b5 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03c5\u03c8\u03b7\u03bb\u03cc \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 VIII, lupus anticoagulant, \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf \u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03c0\u03ae\u03be\u03b7\u03c2, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03c4\u03bf\u03c0\u03c4\u03c1\u03af\u03b6\u03b5\u03b9 \u03b1\u03be\u03b9\u03cc\u03c0\u03b9\u03c3\u03c4\u03b1 \u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a4\u03bf <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/inr-exetasi\/\">INR<\/a> \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b5\u03be\u03c9\u03b3\u03b5\u03bd\u03ae \u03bf\u03b4\u03cc \u03c0\u03ae\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b3\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ce\u03bd \u03b2\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7\u03c2 \u039a, \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03b2\u03b1\u03c1\u03c6\u03b1\u03c1\u03af\u03bd\u03b7. \u0394\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03bf \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03bf \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2, LMWH \u03ae fondaparinux \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03ba\u03c1\u03b9\u03b8\u03b5\u03af \u03b7 \u03b4\u03cc\u03c3\u03b7 \u03c4\u03bf\u03c5\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 Anti-Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03ba\u03bf\u03bd\u03c4\u03ac \u03c3\u03c4\u03bf \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1 \u00ab\u03c0\u03cc\u03c3\u03b7 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03bf\u03c5 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 Xa \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf\u00bb. \u0391\u03c5\u03c4\u03cc \u03c4\u03b7\u03bd \u03ba\u03ac\u03bd\u03b5\u03b9 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03b3\u03b9\u03b1 UFH \u03ba\u03b1\u03b9 LMWH \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7. \u038c\u03bc\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03b4\u03ce \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae: \u03b7 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ae Anti-Xa \u03b3\u03b9\u03b1 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03af\u03b4\u03b9\u03b1 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 calibrated Anti-Xa \u03bc\u03b5\u03b8\u03cc\u03b4\u03bf\u03c5\u03c2 \u03b3\u03b9\u03b1 \u03ac\u03bc\u03b5\u03c3\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ac.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 12px 0;\">\u2194\ufe0f \u03a3\u03cd\u03c1\u03b5\u03c4\u03b5 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03c4\u03ae\u03bb\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03af\u03bd\u03b1\u03ba\u03b1<\/div>\n<div style=\"overflow-x: auto; margin: 10px 0 16px;\">\n<table style=\"width: 100%; border-collapse: collapse; min-width: 760px; color: #111827; font-size: 14px;\">\n<thead style=\"background: #f3f4f6;\">\n<tr>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">\u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/th>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">\u03a4\u03b9 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af<\/th>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">\u039a\u03cd\u03c1\u03b9\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b7<\/th>\n<th style=\"border: 1px solid #d1d5db; padding: 9px; text-align: left;\">\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc\u03c2<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">Anti-Xa \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0391\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 Xa \u03b1\u03c0\u03cc \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">UFH\/LMWH \u03c3\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0391\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c3\u03c9\u03c3\u03c4\u03cc timing \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b7 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">aPTT<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0395\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae\u03c2\/\u03ba\u03bf\u03b9\u03bd\u03ae \u03bf\u03b4\u03cc\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">UFH, \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03c0\u03b1\u03c1\u03ac\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0395\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2, \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03ba\u03b1\u03b9 LA<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">INR<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0395\u03be\u03c9\u03b3\u03b5\u03bd\u03ae\u03c2 \u03bf\u03b4\u03cc\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0392\u03b1\u03c1\u03c6\u03b1\u03c1\u03af\u03bd\u03b7 \/ \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ad\u03c2 \u03b2\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7\u03c2 \u039a<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0394\u03b5\u03bd \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03ae LMWH<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">Calibrated Anti-Xa \u03b3\u03b9\u03b1 DOAC<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0395\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03b1 Xa<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">Rivaroxaban, apixaban, edoxaban \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 9px;\">\u0391\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc calibrator \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a4\u03b1 DOACs \u03cc\u03c0\u03c9\u03c2 rivaroxaban \u03ba\u03b1\u03b9 apixaban \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ae Anti-Xa \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03ae\u03c3\u03bf\u03c5\u03bd \u03c8\u03b5\u03c5\u03b4\u03ce\u03c2 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1, \u03b1\u03bd \u03bf \u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b1\u03bd\u03c4\u03b9\u03b4\u03c1\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b2\u03b1\u03b8\u03bc\u03bf\u03bd\u03bf\u03bc\u03b7\u03bc\u03ad\u03bd\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf \u03bd\u03b1 \u03b4\u03b7\u03bb\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2.<\/p>\n<p><!-- ==================== SECTION 10 ==================== --><\/p>\n<h2 id=\"sec10\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">10<\/span><\/span>Anti-Xa \u03c3\u03c4\u03b7\u03bd \u03b5\u03bd\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae, ECMO \u03ba\u03b1\u03b9 \u03b2\u03b1\u03c1\u03b9\u03ac \u03bd\u03cc\u03c3\u03bf<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u03a3\u03c4\u03b7\u03bd \u03b5\u03bd\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf ECMO, \u03b7 Anti-Xa \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03c4\u03bf aPTT \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c3\u03c4\u03b1\u03b8\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03cd\u03c3\u03ba\u03bf\u03bb\u03bf \u03bd\u03b1 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03c5\u03c4\u03b5\u03af.<\/strong> \u039f\u03b9 \u03b2\u03b1\u03c1\u03ad\u03c9\u03c2 \u03c0\u03ac\u03c3\u03c7\u03bf\u03bd\u03c4\u03b5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b4\u03c5\u03bd\u03b1\u03bc\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03ae\u03be\u03b7, \u03c3\u03c4\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03c3\u03c4\u03bf\u03bd \u03cc\u03b3\u03ba\u03bf \u03ba\u03b1\u03c4\u03b1\u03bd\u03bf\u03bc\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03b5 \u03c3\u03ae\u03c8\u03b7, \u03c0\u03bf\u03bb\u03c5\u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03ba\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1, \u03bc\u03b1\u03b6\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b3\u03b3\u03af\u03c3\u03b5\u03b9\u03c2, \u03b1\u03b9\u03bc\u03bf\u03b1\u03c1\u03b1\u03af\u03c9\u03c3\u03b7 \u03ae \u03ad\u03bd\u03c4\u03bf\u03bd\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7, \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03c0\u03ae\u03be\u03b7\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03b1. \u03a4\u03bf aPTT \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ae \u03bd\u03b1 \u03b2\u03c1\u03b1\u03c7\u03cd\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bb\u03cc\u03b3\u03bf\u03c5\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7 UFH. \u0391\u03c5\u03c4\u03cc \u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03b7\u03bd Anti-Xa \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03c9\u03c2 \u03c0\u03b9\u03bf \u03ac\u03bc\u03b5\u03c3\u03bf \u03b4\u03b5\u03af\u03ba\u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03c4\u03bf ECMO, \u03c4\u03bf \u03ba\u03cd\u03ba\u03bb\u03c9\u03bc\u03b1 \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2. \u03a4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03c5\u03ba\u03bb\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1\u03c2. \u0397 \u03b9\u03c3\u03bf\u03c1\u03c1\u03bf\u03c0\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bb\u03b5\u03c0\u03c4\u03ae. \u0397 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c4\u03b7 \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 UFH, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03bc\u03cc\u03bd\u03bf\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u03a3\u03c4\u03b7\u03bd \u03b5\u03bd\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bd\u03b5\u03ba\u03c4\u03b9\u03bc\u03ce\u03bd\u03c4\u03b1\u03b9:<\/strong><br \/>\n\u2022 Anti-Xa \u03ba\u03b1\u03b9\/\u03ae aPTT \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf \u03bc\u03bf\u03bd\u03ac\u03b4\u03b1\u03c2<br \/>\n\u2022 \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b3\u03b3\u03af\u03c3\u03b5\u03c9\u03bd<br \/>\n\u2022 \u03b1\u03b9\u03bc\u03bf\u03c0\u03b5\u03c4\u03ac\u03bb\u03b9\u03b1, \u03b9\u03bd\u03c9\u03b4\u03bf\u03b3\u03cc\u03bd\u03bf, PT\/INR \u03ba\u03b1\u03b9 D-Dimer \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9<br \/>\n\u2022 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c6\u03af\u03bb\u03c4\u03c1\u03c9\u03bd, \u03b3\u03c1\u03b1\u03bc\u03bc\u03ce\u03bd \u03ba\u03b1\u03b9 ECMO \u03ba\u03c5\u03ba\u03bb\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2<br \/>\n\u2022 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7, \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03c6\u03b1\u03b9\u03bd\u03bf\u03bc\u03b5\u03bd\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c3\u03b5 \u03b2\u03b1\u03c1\u03b9\u03ac \u03bd\u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7. \u03a3\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7, \u03b7 \u03b1\u03c0\u03bb\u03ae \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 UFH \u03c7\u03c9\u03c1\u03af\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03b9\u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03b7. \u039f \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/antithrombin-iii-exetasi\/\">\u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2<\/a> \u03b2\u03bf\u03b7\u03b8\u03ac \u03bd\u03b1 \u03be\u03b5\u03c7\u03c9\u03c1\u03af\u03c3\u03b5\u03b9 \u03b7 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03b5\u03c0\u03b1\u03c1\u03ba\u03ae \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b5\u03bd\u03b5\u03c1\u03b3\u03cc \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7, \u03bf \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/d-dimeri-d-dimers-ti-einai-giati-afxanontai-kai-pote-einai-anisychitika\/\">D-Dimer<\/a> \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03c3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2\/\u03b9\u03bd\u03c9\u03b4\u03cc\u03bb\u03c5\u03c3\u03b7\u03c2, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03b7\u03bd Anti-Xa \u03b3\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2. \u039a\u03ac\u03b8\u03b5 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03c0\u03b1\u03bd\u03c4\u03ac \u03c3\u03b5 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03cc \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1.<\/p>\n<p><!-- ==================== SECTION 11 ==================== --><\/p>\n<h2 id=\"sec11\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">11<\/span><\/span>\u0391\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03c8\u03b5\u03c5\u03b4\u03ce\u03c2 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ad\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b1\u03c3\u03ba\u03ae\u03c3\u03b5\u03b9 \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2 \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7.<\/strong> \u038c\u03c4\u03b1\u03bd \u03b7 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae, \u03b7 \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd UFH \u03ae \u03c3\u03c4\u03b7 LMWH \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03b7 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b1\u03bd\u03b1\u03bc\u03b5\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf \u03c4\u03bf\u03c5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03bf\u03c5.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c6\u03c5\u03c3\u03b9\u03ba\u03cc\u03c2 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2. \u0391\u03bd\u03b1\u03c3\u03c4\u03ad\u03bb\u03bb\u03b5\u03b9 \u03ad\u03bd\u03b6\u03c5\u03bc\u03b1 \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03bf \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 Xa. \u0397 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03b5\u03bd\u03b9\u03c3\u03c7\u03cd\u03b5\u03b9 \u03b4\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2. \u0395\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2, \u03b1\u03bd \u03b7 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b5\u03c0\u03b1\u03c1\u03ba\u03ae\u03c2, \u03b7 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b7\u03bd \u03b1\u03c0\u03bf\u03b4\u03af\u03b4\u03b5\u03b9 \u03cc\u03c0\u03c9\u03c2 \u03b1\u03bd\u03b1\u03bc\u03ad\u03bd\u03b5\u03c4\u03b1\u03b9.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a7\u03b1\u03bc\u03b7\u03bb\u03ae \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03b3\u03b3\u03b5\u03bd\u03ae\u03c2 \u03ae \u03b5\u03c0\u03af\u03ba\u03c4\u03b7\u03c4\u03b7. \u0395\u03c0\u03af\u03ba\u03c4\u03b7\u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c3\u03ae\u03c8\u03b7, \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf, \u03bd\u03b5\u03c6\u03c1\u03c9\u03c3\u03b9\u03ba\u03cc \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf, \u03b4\u03b9\u03ac\u03c7\u03c5\u03c4\u03b7 \u03b5\u03bd\u03b4\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03c0\u03ae\u03be\u03b7, \u03b5\u03ba\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7, ECMO, \u03bc\u03b5\u03b3\u03ac\u03bb\u03b5\u03c2 \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03c0\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03b1\u03bd\u03ac\u03bb\u03c9\u03c3\u03b7 \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03c0\u03ae\u03be\u03b7\u03c2. \u03a3\u03b5 \u03bd\u03b5\u03bf\u03b3\u03bd\u03ac \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03c4\u03c9\u03bd \u03b5\u03bd\u03b7\u03bb\u03af\u03ba\u03c9\u03bd.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u03a0\u03cc\u03c4\u03b5 \u03bd\u03b1 \u03b5\u03bb\u03b5\u03b3\u03c7\u03b8\u03b5\u03af \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 Anti-Xa:<\/strong><br \/>\n\u2022 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae Anti-Xa \u03c0\u03b1\u03c1\u03ac \u03b1\u03c5\u03be\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03b7 \u03b4\u03cc\u03c3\u03b7 UFH<br \/>\n\u2022 ICU, ECMO, \u03c3\u03ae\u03c8\u03b7 \u03ae \u03b2\u03b1\u03c1\u03b9\u03ac \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7\u03c2 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7<br \/>\n\u2022 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7<br \/>\n\u2022 \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03b8\u03c1\u03bf\u03bc\u03b2\u03bf\u03c6\u03b9\u03bb\u03af\u03b1\u03c2 \u03ae \u03b1\u03bd\u03b5\u03be\u03ae\u03b3\u03b7\u03c4\u03b7\u03c2 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7\u03c2<br \/>\n\u2022 \u03bd\u03b5\u03bf\u03b3\u03bd\u03ac \u03ae \u03c0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 \u03c0\u03b1\u03b3\u03af\u03b4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u00ab\u03c4\u03c5\u03c6\u03bb\u03ae\u00bb \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 UFH \u03cc\u03c4\u03b1\u03bd \u03b7 Anti-Xa \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae. \u0391\u03bd \u03c4\u03bf \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7, \u03b7 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b7\u03bd \u03b4\u03b9\u03bf\u03c1\u03b8\u03ce\u03c3\u03b5\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1\u03c2 \u03cc\u03c4\u03b1\u03bd \u03b7 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03b8\u03b5\u03af.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc, \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03ba\u03bb\u03b7\u03c1\u03bf\u03bd\u03bf\u03bc\u03b9\u03ba\u03ae \u03ae \u03b5\u03c0\u03af\u03ba\u03c4\u03b7\u03c4\u03b7 \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1, \u03b7 Anti-Xa \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03b2\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/antithrombin-iii-exetasi\/\">\u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7\u03c2 III<\/a> \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c0\u03bb\u03ae\u03c1\u03b5\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf. \u03a3\u03b5 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03b8\u03c1\u03bf\u03bc\u03b2\u03bf\u03c6\u03b9\u03bb\u03af\u03b1\u03c2, \u03b7 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03a0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 C, \u03a0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 S \u03ba\u03b1\u03b9 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2.<\/p>\n<p><!-- ==================== SECTION 12 ==================== --><\/p>\n<h2 id=\"sec12\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">12<\/span><\/span>\u03a3\u03c5\u03c7\u03bd\u03ac \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ac \u03c3\u03c6\u03ac\u03bb\u03bc\u03b1\u03c4\u03b1<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u03a4\u03b1 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03bf\u03be\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 Anti-Xa \u03bf\u03c6\u03b5\u03af\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bb\u03ac\u03b8\u03bf\u03c2 timing, \u03bb\u03ac\u03b8\u03bf\u03c2 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03ae \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03bf\u03c2.<\/strong> \u03a0\u03c1\u03b9\u03bd \u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9 \u03b7 \u03b4\u03cc\u03c3\u03b7, \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b1\u03c0\u03bb\u03ac \u03b1\u03bb\u03bb\u03ac \u03c3\u03c5\u03c7\u03bd\u03ac \u03c3\u03c6\u03ac\u03bb\u03bc\u03b1\u03c4\u03b1.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a4\u03bf \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf \u03bb\u03ac\u03b8\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03b5\u03ba\u03c4\u03cc\u03c2 peak. \u0391\u03bd \u03b7 LMWH \u03b4\u03cc\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03b9\u03c2 08:00 \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03c3\u03c4\u03b9\u03c2 10:00 \u03ae \u03c3\u03c4\u03b9\u03c2 15:00, \u03b7 \u03c4\u03b9\u03bc\u03ae \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af \u03c3\u03c4\u03bf \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03cc peak \u03c4\u03c9\u03bd 4 \u03c9\u03c1\u03ce\u03bd. \u0391\u03bd \u03c3\u03c5\u03b3\u03ba\u03c1\u03b9\u03b8\u03b5\u03af \u03bc\u03b5 \u03c3\u03c4\u03cc\u03c7\u03bf\u03c5\u03c2 peak, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03bb\u03ac\u03b8\u03bf\u03c2 \u03c3\u03c5\u03bc\u03c0\u03ad\u03c1\u03b1\u03c3\u03bc\u03b1.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0394\u03b5\u03cd\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03cc \u03bb\u03ac\u03b8\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03bb\u03ae\u03c8\u03b7 \u03b1\u03c0\u03cc \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae \u03bc\u03b5 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7. \u0391\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03b9\u03ba\u03c1\u03ae \u03b5\u03c0\u03b9\u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03b5\u03b9 \u03c4\u03b5\u03c7\u03bd\u03b7\u03c4\u03ac \u03c4\u03b7\u03bd Anti-Xa \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b4\u03ce\u03c3\u03b5\u03b9 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c5\u03c0\u03b5\u03c1\u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2. \u0391\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c3\u03b5 \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03c5\u03cc\u03bc\u03b5\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2, \u03cc\u03c0\u03bf\u03c5 \u03bf\u03b9 \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03ad\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b1 flushes \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u039b\u03ac\u03b8\u03bf\u03c2 \u03c0\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7 \u03c3\u03c9\u03bb\u03ae\u03bd\u03b1 \u03ba\u03b9\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd, \u03c0\u03ae\u03b3\u03bc\u03b1 \u03c3\u03c4\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1, \u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7, \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7 \u03c3\u03c4\u03b7 \u03c6\u03c5\u03b3\u03bf\u03ba\u03ad\u03bd\u03c4\u03c1\u03b7\u03c3\u03b7, \u03b1\u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b7 \u03c6\u03cd\u03bb\u03b1\u03be\u03b7 \u03ae \u03bb\u03b1\u03bd\u03b8\u03b1\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b2\u03b1\u03b8\u03bc\u03bf\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7 \u03bc\u03b5\u03b8\u03cc\u03b4\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1. \u03a3\u03c4\u03b7\u03bd Anti-Xa, \u03b7 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf-\u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c4\u03b1\u03b4\u03af\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03cc\u03c3\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03ae \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae checklist \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1:<\/strong><br \/>\n\u2022 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03ba\u03b1\u03b9 \u03b7 \u03b4\u03cc\u03c3\u03b7;<br \/>\n\u2022 \u03b3\u03c1\u03ac\u03c6\u03c4\u03b7\u03ba\u03b5 \u03b7 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ae\u03c2 \u03ce\u03c1\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2;<br \/>\n\u2022 \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03c3\u03c4\u03bf \u03c3\u03c9\u03c3\u03c4\u03cc \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03c3\u03b7\u03bc\u03b5\u03af\u03bf;<br \/>\n\u2022 \u03c4\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03b4\u03b5\u03bd \u03bb\u03ae\u03c6\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03b7\u03c0\u03b1\u03c1\u03b9\u03bd\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae;<br \/>\n\u2022 \u03bf \u03c3\u03c9\u03bb\u03ae\u03bd\u03b1\u03c2 \u03ba\u03b9\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd \u03b3\u03ad\u03bc\u03b9\u03c3\u03b5 \u03c3\u03c9\u03c3\u03c4\u03ac;<br \/>\n\u2022 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03bf\u03bb\u03ae \u03b1\u03c0\u03cc DOAC;<br \/>\n\u2022 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b7 \u03b2\u03b1\u03b8\u03bc\u03bf\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf;<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bd\u03b1 \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c3\u03c7\u03cc\u03bb\u03b9\u03bf \u03b3\u03b9\u03b1 \u03c4\u03bf timing \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf. \u0388\u03c4\u03c3\u03b9 \u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc\u03c2 \u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03b4\u03b5\u03bd \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03ad\u03bd\u03b1\u03bd \u03b1\u03c0\u03bf\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc, \u03b1\u03bb\u03bb\u03ac \u03bc\u03b9\u03b1 \u03c4\u03b9\u03bc\u03ae \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bd\u03c4\u03b1\u03c7\u03b8\u03b5\u03af \u03c3\u03c4\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf.<\/p>\n<p><!-- ==================== SECTION 13 ==================== --><\/p>\n<h2 id=\"sec13\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">13<\/span><\/span>\u03a0\u03cc\u03c4\u03b5 \u03b4\u03b5\u03bd \u03b5\u03bd\u03b4\u03b5\u03af\u03ba\u03bd\u03c5\u03c4\u03b1\u03b9 \u03b7 Anti-Xa<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 Anti-Xa \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03c1\u03bf\u03c5\u03c4\u03af\u03bd\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03cc.<\/strong> \u038c\u03c4\u03b1\u03bd \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03b1\u03c6\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7 \u03ae \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03c9\u03c3\u03c4\u03cc timing, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c3\u03cd\u03b3\u03c7\u03c5\u03c3\u03b7 \u03c0\u03b1\u03c1\u03ac \u03b2\u03bf\u03ae\u03b8\u03b5\u03b9\u03b1.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0394\u03b5\u03bd \u03b5\u03bd\u03b4\u03b5\u03af\u03ba\u03bd\u03c5\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03b3\u03b5\u03bd\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u00ab\u03c0\u03ae\u03be\u03b7\u03c2\u00bb \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03ae \u03c3\u03c5\u03b3\u03b3\u03b5\u03bd\u03ad\u03c2 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf. \u0393\u03b9\u03b1 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7\u03c2, \u03c0\u03b1\u03c1\u03ac\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2 \u03ae \u03c0\u03c1\u03bf\u03b5\u03b3\u03c7\u03b5\u03b9\u03c1\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03cc\u03c0\u03c9\u03c2 PT\/INR, aPTT, \u03b9\u03bd\u03c9\u03b4\u03bf\u03b3\u03cc\u03bd\u03bf, \u03b1\u03b9\u03bc\u03bf\u03c0\u03b5\u03c4\u03ac\u03bb\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03af \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03c0\u03ae\u03be\u03b7\u03c2, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0394\u03b5\u03bd \u03b5\u03bd\u03b4\u03b5\u03af\u03ba\u03bd\u03c5\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c9\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7\u03c2. \u0393\u03b9\u03b1 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c6\u03bb\u03b5\u03b2\u03b9\u03ba\u03ae\u03c2 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7\u03c2 \u03ae \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b5\u03bc\u03b2\u03bf\u03bb\u03ae\u03c2, \u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1, \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03ba\u03b1\u03b9, \u03cc\u03c0\u03bf\u03c5 \u03b5\u03bd\u03b4\u03b5\u03af\u03ba\u03bd\u03c5\u03c4\u03b1\u03b9, <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/d-dimeri-d-dimers-ti-einai-giati-afxanontai-kai-pote-einai-anisychitika\/\">D-Dimer<\/a>. \u0397 Anti-Xa \u03b1\u03c0\u03b1\u03bd\u03c4\u03ac \u03c3\u03c4\u03bf \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2, \u03cc\u03c7\u03b9 \u03c3\u03c4\u03bf \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b8\u03c1\u03cc\u03bc\u03b2\u03bf\u03c2.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u0394\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03ac\u03bc\u03b5\u03c3\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ce\u03bd, \u03b5\u03ba\u03c4\u03cc\u03c2 \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae calibrated \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf DOAC. \u0388\u03bd\u03b1 \u03b1\u03c0\u03bb\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 Anti-Xa \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 rivaroxaban \u03ae apixaban \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03c0\u03bb\u03b1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u0394\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03be\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd:<\/strong><br \/>\n\u2022 \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae LMWH \u03c7\u03c9\u03c1\u03af\u03c2 \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf<br \/>\n\u2022 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae \u03b7 \u03ce\u03c1\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2<br \/>\n\u2022 \u03c4\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03c5\u03c7\u03b1\u03af\u03bf \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af \u03c3\u03b5 peak\/steady-state<br \/>\n\u2022 \u03c4\u03bf \u03b6\u03b7\u03c4\u03bf\u03cd\u03bc\u03b5\u03bd\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2<br \/>\n\u2022 \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 DOAC \u03c7\u03c9\u03c1\u03af\u03c2 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae calibrated \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u0397 \u03c3\u03c9\u03c3\u03c4\u03ae \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03b7\u03c2 Anti-Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7. \u038c\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03b1\u03c6\u03ad\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03cc \u03c0\u03c1\u03bf-\u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf, \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd\u03c4\u03b9\u03bc\u03b7. \u038c\u03c4\u03b1\u03bd \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b1\u03c5\u03c4\u03ac, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03ac\u03c3\u03ba\u03bf\u03c0\u03b5\u03c2 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae.<\/p>\n<p><!-- ==================== SECTION 14 ==================== --><\/p>\n<h2 id=\"sec14\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">14<\/span><\/span>Anti-Xa \u03c3\u03b5 30\u2019\u2019 \u03b3\u03b9\u03b1 \u03b5\u03c0\u03b1\u03b3\u03b3\u03b5\u03bb\u03bc\u03b1\u03c4\u03af\u03b5\u03c2 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 Anti-Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03be\u03b9\u03cc\u03c0\u03b9\u03c3\u03c4\u03b7 \u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b4\u03b5\u03b8\u03b5\u03af \u03bc\u03b5 \u03c3\u03c9\u03c3\u03c4\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf, \u03c3\u03c9\u03c3\u03c4\u03ae \u03b4\u03cc\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03cc timing.<\/strong><\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>\u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03bf\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc\u03c2 \u03bf\u03b4\u03b7\u03b3\u03cc\u03c2:<\/strong><br \/>\n\u2022 UFH: \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 \u03c3\u03c5\u03c7\u03bd\u03ac 0.3\u20130.7 IU\/mL, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf<br \/>\n\u2022 LMWH BID \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae: peak 4h, \u03c3\u03c5\u03c7\u03bd\u03cc\u03c2 \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 0.5\u20131.0 IU\/mL<br \/>\n\u2022 LMWH QD \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae: peak 4h, \u03c3\u03c5\u03c7\u03bd\u03cc\u03c2 \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 1.0\u20132.0 IU\/mL<br \/>\n\u2022 LMWH \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae: monitoring \u03bc\u03cc\u03bd\u03bf \u03c3\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<br \/>\n\u2022 Fondaparinux: \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03b2\u03b1\u03b8\u03bc\u03bf\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7<br \/>\n\u2022 DOACs: \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 drug-calibrated assays, \u03cc\u03c7\u03b9 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ae Anti-Xa \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2<\/div>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 UFH \u03ba\u03b1\u03b9 \u03b1\u03c3\u03c5\u03bc\u03c6\u03c9\u03bd\u03af\u03b1 aPTT\/\u03b4\u03cc\u03c3\u03b7\u03c2, \u03b7 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c4\u03b9\u03bc\u03cc\u03c4\u03b5\u03c1\u03b7, \u03b9\u03b4\u03af\u03c9\u03c2 \u03c3\u03b5 ICU, ECMO, \u03c3\u03ae\u03c8\u03b7, \u03c5\u03c8\u03b7\u03bb\u03cc FVIII \u03ae lupus anticoagulant. \u03a3\u03b5 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae Anti-Xa \u03c0\u03b1\u03c1\u03ac \u03c5\u03c8\u03b7\u03bb\u03ad\u03c2 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 UFH, \u03b5\u03bb\u03ad\u03b3\u03be\u03c4\u03b5 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03c0\u03c1\u03b9\u03bd \u03b1\u03c5\u03be\u03ae\u03c3\u03b5\u03c4\u03b5 \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 LMWH \u03ba\u03b1\u03b9 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03bc\u03b7\u03bd \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b5 \u03bc\u03cc\u03bd\u03bf \u03c4\u03b7\u03bd Anti-Xa. \u03a3\u03c5\u03bd\u03b5\u03ba\u03c4\u03b9\u03bc\u03ae\u03c3\u03c4\u03b5 eGFR, \u03b7\u03bb\u03b9\u03ba\u03af\u03b1, \u03b2\u03ac\u03c1\u03bf\u03c2, \u03b1\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03b9 \u03c7\u03c1\u03cc\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b4\u03cc\u03c3\u03b7. \u0397 \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc eGFR.<\/p>\n<p style=\"line-height: 1.8; color: #111827;\">\u03a3\u03b5 \u03ba\u03cd\u03b7\u03c3\u03b7, \u03bc\u03b7\u03bd \u03b5\u03c6\u03b1\u03c1\u03bc\u03cc\u03b6\u03b5\u03c4\u03b5 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03ba\u03ac monitoring \u03c3\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2. \u03a7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03c4\u03b5 Anti-Xa \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae, \u03c5\u03c8\u03b7\u03bb\u03cc\u03c2 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2, \u03b1\u03ba\u03c1\u03b1\u03af\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03ae \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf. \u039f \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af \u03c3\u03c4\u03bf \u03c3\u03c7\u03ae\u03bc\u03b1 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2.<\/p>\n<div style=\"background: #fff7ed; border-left: 4px solid #ea580c; border-radius: 10px; padding: 12px 14px; margin: 12px 0; line-height: 1.7;\"><strong>Bottom line:<\/strong> \u03c3\u03c9\u03c3\u03c4\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7 + \u03c3\u03c9\u03c3\u03c4\u03cc timing + \u03c3\u03c9\u03c3\u03c4\u03ae \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 + \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7. \u03a7\u03c9\u03c1\u03af\u03c2 \u03b1\u03c5\u03c4\u03ac, \u03b7 Anti-Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2 \u03bc\u03b5 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b1\u03be\u03af\u03b1.<\/div>\n<p><!-- ==================== SECTION 15 ==================== --><\/p>\n<h2 id=\"faq\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">15<\/span><\/span>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b5\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a4\u03b9 \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 Anti-Xa;<\/summary>\n<p>\u0394\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03ad\u03bd\u03c4\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 Xa \u03b1\u03c0\u03cc \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03ae \u03c3\u03c5\u03b3\u03b3\u03b5\u03bd\u03ad\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03cc, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03b2\u03bf\u03b7\u03b8\u03ac \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 Anti-Xa;<\/summary>\n<p>\u038c\u03c7\u03b9, \u03b4\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1\u00b7 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03bc\u03c9\u03c2 \u03c3\u03c9\u03c3\u03c4\u03ae \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03ae \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5, \u03b4\u03cc\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ce\u03c1\u03b1\u03c2 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a0\u03cc\u03c4\u03b5 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9 \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03b3\u03b9\u03b1 LMWH;<\/summary>\n<p>\u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 4 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03b4\u03cc\u03c1\u03b9\u03b1 \u03b4\u03cc\u03c3\u03b7, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03bc\u03b5\u03c4\u03c1\u03b7\u03b8\u03b5\u03af \u03c4\u03bf peak \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a0\u03cc\u03c4\u03b5 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 Anti-Xa \u03c3\u03b5 UFH;<\/summary>\n<p>\u03a3\u03b5 \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03ad\u03b2\u03b9\u03b1 UFH \u03bc\u03b5\u03c4\u03c1\u03b9\u03ad\u03c4\u03b1\u03b9 \u03b1\u03c6\u03bf\u03cd \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03b7 \u03ad\u03b3\u03c7\u03c5\u03c3\u03b7 \u03ae \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c1\u03c5\u03b8\u03bc\u03bf\u03cd, \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf \u03c4\u03bf\u03c5 \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03bf\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a0\u03bf\u03b9\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 Anti-Xa \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2;<\/summary>\n<p>\u03a3\u03c5\u03c7\u03bd\u03ac \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 0.3\u20130.7 IU\/mL \u03b3\u03b9\u03b1 UFH, 0.5\u20131.0 IU\/mL \u03b3\u03b9\u03b1 LMWH \u03b4\u03cd\u03bf \u03c6\u03bf\u03c1\u03ad\u03c2 \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2 \u03ba\u03b1\u03b9 1.0\u20132.0 IU\/mL \u03b3\u03b9\u03b1 LMWH \u03ac\u03c0\u03b1\u03be \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03cc\u03bb\u03bf\u03b9 \u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 LMWH \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf Anti-Xa;<\/summary>\n<p>\u038c\u03c7\u03b9, \u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03bf\u03af \u03b5\u03bd\u03ae\u03bb\u03b9\u03ba\u03b5\u03c2 \u03b4\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c1\u03bf\u03c5\u03c4\u03af\u03bd\u03b1 monitoring\u00b7 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03b5 \u03ba\u03cd\u03b7\u03c3\u03b7, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03b1\u03ba\u03c1\u03b1\u03af\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2, \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03ae \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03b7 Anti-Xa \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03b3\u03b9\u03b1 Xarelto \u03ae Eliquis;<\/summary>\n<p>\u0397 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ae Anti-Xa \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b7 \u03b3\u03b9\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 DOACs\u00b7 \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac calibrated assays \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0393\u03b9\u03b1\u03c4\u03af \u03b7 Anti-Xa \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03b3\u03b5\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03b5\u03bd\u03ce \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7;<\/summary>\n<p>\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03c6\u03b5\u03af\u03bb\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bb\u03ac\u03b8\u03bf\u03c2 timing, \u03c0\u03c1\u03bf-\u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03cc \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03ae \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7, \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03b2\u03b1\u03c1\u03b9\u03ac \u03bd\u03cc\u03c3\u03bf \u03ae ECMO.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03c5\u03c8\u03b7\u03bb\u03ae Anti-Xa;<\/summary>\n<p>\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03ae \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5, \u03b1\u03bb\u03bb\u03ac \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03c0\u03c1\u03ce\u03c4\u03b1 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03c9\u03b8\u03bf\u03cd\u03bd \u03c4\u03bf timing, \u03b7 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b5\u03c0\u03b9\u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0397 Anti-Xa \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03b1\u03bd \u03ad\u03c7\u03c9 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7;<\/summary>\n<p>\u038c\u03c7\u03b9, \u03b7 Anti-Xa \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af \u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9 \u03c4\u03c5\u03c7\u03b1\u03af\u03b1 \u03bf\u03c0\u03bf\u03b9\u03b1\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03ce\u03c1\u03b1;<\/summary>\n<p>\u038c\u03c7\u03b9 \u03b1\u03be\u03b9\u03cc\u03c0\u03b9\u03c3\u03c4\u03b1\u00b7 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03c9\u03c3\u03c4\u03cc timing \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7, \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b7\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03c3\u03b9\u03bc\u03bf.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a0\u03bf\u03b9\u03b1 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b4\u03bf\u03b8\u03b5\u03af \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf;<\/summary>\n<p>\u03a0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b4\u03b7\u03bb\u03c9\u03b8\u03bf\u03cd\u03bd \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf, \u03b7 \u03b4\u03cc\u03c3\u03b7, \u03b7 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1, \u03b7 \u03ce\u03c1\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2, \u03b7 \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03c5\u03c7\u03cc\u03bd \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03ae \u03bb\u03ae\u03c8\u03b7 \u03ac\u03bb\u03bb\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03bf\u03cd.<\/p>\n<\/details>\n<p><!-- ==================== SECTION 16 ==================== --><\/p>\n<h2 id=\"sec16\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">16<\/span><\/span>\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/h2>\n<p style=\"line-height: 1.8; color: #111827;\"><strong>\u0397 Anti-Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03bf \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c9\u03c3\u03c4\u03ac, \u03b1\u03bb\u03bb\u03ac \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03c0\u03bb\u03b1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03cc\u03c4\u03b1\u03bd \u03bb\u03b5\u03af\u03c0\u03b5\u03b9 \u03c4\u03bf timing \u03ae \u03c4\u03bf \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf.<\/strong><\/p>\n<ul style=\"line-height: 1.8; color: #111827; padding-left: 22px;\">\n<li>\u0397 Anti-Xa \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b3\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 UFH, LMWH \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 fondaparinux \u03bc\u03b5 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf.<\/li>\n<li>\u0394\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2 \u03b8\u03c1\u03cc\u03bc\u03b2\u03c9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac D-Dimer, \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03ae \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03b8\u03c1\u03bf\u03bc\u03b2\u03bf\u03c6\u03b9\u03bb\u03af\u03b1\u03c2.<\/li>\n<li>\u0393\u03b9\u03b1 LMWH \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 4 \u03ce\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03bc\u03b5\u03c4\u03c1\u03b7\u03b8\u03b5\u03af \u03c4\u03bf peak.<\/li>\n<li>\u0393\u03b9\u03b1 UFH \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ad\u03b3\u03c7\u03c5\u03c3\u03b7\u03c2 \u03ae \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c1\u03c5\u03b8\u03bc\u03bf\u03cd, \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03bf.<\/li>\n<li>\u03a4\u03b1 \u03c3\u03c5\u03bd\u03ae\u03b8\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ac \u03b5\u03cd\u03c1\u03b7 \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03b1\u03bd\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf, \u03c3\u03c7\u03ae\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf.<\/li>\n<li>\u039d\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03ba\u03cd\u03b7\u03c3\u03b7, \u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1, \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03ba\u03b1\u03b9 ICU\/ECMO \u03b5\u03af\u03bd\u03b1\u03b9 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03bf\u03c5 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b1\u03be\u03af\u03b1.<\/li>\n<li>\u03a7\u03b1\u03bc\u03b7\u03bb\u03ae Anti-Xa \u03c0\u03b1\u03c1\u03ac \u03c5\u03c8\u03b7\u03bb\u03ad\u03c2 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 UFH \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03c3\u03ba\u03ad\u03c8\u03b7 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03c4\u03b9\u03b8\u03c1\u03bf\u03bc\u03b2\u03af\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03b1\u03c5\u03c4\u03cc\u03bc\u03b1\u03c4\u03b1 \u03c3\u03b5 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03b4\u03cc\u03c3\u03b7\u03c2.<\/li>\n<li>\u03a4\u03b1 DOACs \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd Anti-Xa\u00b7 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac calibrated assays \u03b3\u03b9\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7.<\/li>\n<li>\u0397 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03b1\u03c0\u03cc \u03b7\u03c0\u03b1\u03c1\u03b9\u03bd\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03ce\u03c3\u03b5\u03b9 \u03c8\u03b5\u03c5\u03b4\u03ce\u03c2 \u03c5\u03c8\u03b7\u03bb\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1.<\/li>\n<li>\u0397 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03b1 \u03b9\u03b1\u03c4\u03c1\u03cc \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc, \u03c4\u03b7 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03c4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1.<\/li>\n<\/ul>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0; line-height: 1.7;\"><strong>\u039a\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03cc \u03bc\u03ae\u03bd\u03c5\u03bc\u03b1:<\/strong> \u0397 Anti-Xa \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03ad\u03bd\u03b1\u03c2 \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2. \u0395\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03c0\u03bf\u03ba\u03c4\u03ac \u03bd\u03cc\u03b7\u03bc\u03b1 \u03bc\u03cc\u03bd\u03bf \u03cc\u03c4\u03b1\u03bd \u03be\u03ad\u03c1\u03bf\u03c5\u03bc\u03b5 \u03c0\u03bf\u03b9\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03b4\u03cc\u03b8\u03b7\u03ba\u03b5, \u03c0\u03cc\u03c4\u03b5 \u03b4\u03cc\u03b8\u03b7\u03ba\u03b5, \u03c0\u03cc\u03c4\u03b5 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03b7 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03bf\u03b9\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1.<\/div>\n<p><!-- ==================== SECTION 17 ==================== --><\/p>\n<h2 id=\"sec17\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px; font-size: 24px; font-weight: 900; color: #111827;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; background: linear-gradient(180deg,#ffffff,#f3f4f6); border: 1px solid #d1d5db; border-radius: 10px; box-shadow: 0 4px 10px rgba(17,24,39,.10); flex: 0 0 36px;\"><span style=\"font-size: 14px; font-weight: 900; color: #b70000;\">17<\/span><\/span>\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd &amp; \u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/h2>\n<p style=\"text-align: center; line-height: 1.8; color: #111827; margin: 12px 0 14px;\"><strong>\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03b9\u03b1\u03c4\u03c1\u03cc \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03cc \u03bc\u03b1\u03c2. \u039c\u03c0\u03bf\u03c1\u03b5\u03af\u03c4\u03b5 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03c3\u03b5\u03c4\u03b5 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ae \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.<\/strong><\/p>\n<div style=\"background: #fdf2f2; border: 2px solid #b70000; border-radius: 14px; padding: 18px; text-align: center; margin: 14px 0 22px;\">\n<div><strong>\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 Anti-Xa \u03ae \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf:<\/strong><\/div>\n<div style=\"display: flex; gap: 10px; justify-content: center; flex-wrap: wrap; margin-top: 10px;\"><a style=\"background: #b70000; color: #fff; padding: 0 18px; border-radius: 12px; text-decoration: none; font-weight: 600; display: inline-flex; align-items: center; justify-content: center; width: 200px; height: 44px; white-space: nowrap;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"nofollow noopener\">\ud83d\udcd8 \u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd<\/a><br \/>\n<a style=\"background: #b70000; color: #fff; padding: 0 18px; border-radius: 12px; text-decoration: none; font-weight: 600; display: inline-flex; align-items: center; justify-content: center; width: 200px; height: 44px; white-space: nowrap;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/about-us\/appointments\/\" target=\"_blank\" rel=\"nofollow noopener\">\ud83d\udcc5 \u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd \u03a4\u03ce\u03c1\u03b1<\/a><\/div>\n<div style=\"margin-top: 10px; color: #374151;\">\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n<\/div>\n<h3 style=\"font-size: 20px; font-weight: 900; color: #111827; margin: 22px 0 10px;\">\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/h3>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">Baker P, Baglin T, Kitchen S, et al. <em>Guidelines on the laboratory aspects of assays used in haemostasis and thrombosis.<\/em> British Journal of Haematology. 2024.<br \/>\n<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/bjh.19729\" target=\"_blank\" rel=\"noopener\">https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/bjh.19729<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">American Society of Hematology. <em>2018 guidelines for management of venous thromboembolism in the context of pregnancy.<\/em> Blood Advances. 2018.<br \/>\nhttps:\/\/ashpublications.org\/bloodadvances\/article\/2\/22\/3317\/16094\/<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">ISTH SSC draft guidance. <em>How to monitor and manage unfractionated heparin in clinical practice.<\/em> 2025.<br \/>\nhttps:\/\/cdn.ymaws.com\/www.isth.org\/resource\/resmgr\/guidance_and_guidelines\/Guidance_UFH_PublicComments_.pdf<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">Gloucestershire Hospitals NHS Foundation Trust. <em>Heparin Anti-Xa Assay \u2013 sample timing and practical laboratory notes.<\/em><br \/>\nhttps:\/\/www.gloshospitals.nhs.uk\/our-services\/services-we-offer\/pathology\/tests-and-investigations\/heparin-anti-xa-assay\/<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">Rajsic S, et al. <em>Anticoagulation monitoring during ECMO support and anti-factor Xa-guided UFH monitoring.<\/em> 2024.<br \/>\nhttps:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11653157\/<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\"><strong>\u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u2013 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u039b\u03b1\u03bc\u03af\u03b1<\/strong><br \/>\n<a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"noopener\">https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/<\/a><\/div>\n<div style=\"background: #f1f5f9; border-left: 4px solid #2563eb; padding: 10px 14px; border-radius: 8px; margin-top: 10px;\"><strong style=\"color: #1d4ed8;\">\u0395\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03bc\u03ad\u03bb\u03b5\u03b9\u03b1:<\/strong><br \/>\n\u0394\u03c1. \u03a0\u03b1\u03bd\u03c4\u03b5\u03bb\u03ae\u03c2 \u0391\u03bd\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03cc\u03c0\u03bf\u03c5\u03bb\u03bf\u03c2, \u0399\u03b1\u03c4\u03c1\u03cc\u03c2 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u2013 \u0392\u03b9\u03bf\u03c0\u03b1\u03b8\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2<br \/>\n\u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u039b\u03b1\u03bc\u03af\u03b1\u03c2, \u0388\u03c3\u03bb\u03b9\u03bd 19, \u039b\u03b1\u03bc\u03af\u03b1 35100<br \/>\n\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Anti-Xa: \u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u0391\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u0397\u03c0\u03b1\u03c1\u03af\u03bd\u03b7\u03c2 (UFH, LMWH, Fondaparinux) \u0394\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7: 31 \u0399\u03b1\u03bd\u03bf\u03c5\u03b1\u03c1\u03af\u03bf\u03c5 2026 \u2022 \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7: 31 \u0399\u03b1\u03bd\u03bf\u03c5\u03b1\u03c1\u03af\u03bf\u03c5 2026 \u03a3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7 \u03c0\u03b5\u03c1\u03af\u03bb\u03b7\u03c8\u03b7: \u0397 Anti-Xa \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b5\u03ba\u03c4\u03b9\u03bc\u03b7\u03b8\u03b5\u03af \u03c0\u03cc\u03c3\u03bf \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03b4\u03c1\u03b1 \u03b7 \u03b7\u03c0\u03b1\u03c1\u03af\u03bd\u03b7 \u03c3\u03c4\u03bf\u03bd \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc \u03c0\u03ae\u03be\u03b7\u03c2. \u0388\u03c7\u03b5\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd \u03b7 \u03b1\u03bd\u03c4\u03b9\u03c0\u03b7\u03ba\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03c3\u03b5 UFH, [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":6592,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2534],"tags":[2237,2236,2240,2241,2239,2238,2242,602,165,1651,195,598],"class_list":["post-6591","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exetaseis-aimatos","tag-anti-factor-xa","tag-anti-xa","tag-enoxaparin","tag-fondaparinux","tag-lmwh","tag-ufh","tag-aimostasi","tag-antipiktika","tag-egkymosyni","tag-mikroviologiko-lamia","tag-nefriki-aneparkeia","tag-pixi"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/6591","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/comments?post=6591"}],"version-history":[{"count":6,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/6591\/revisions"}],"predecessor-version":[{"id":11528,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/6591\/revisions\/11528"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media\/6592"}],"wp:attachment":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media?parent=6591"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/categories?post=6591"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/tags?post=6591"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}