{"id":6277,"date":"2025-09-29T07:58:58","date_gmt":"2025-09-29T04:58:58","guid":{"rendered":"https:\/\/mikrobiologikolamia.gr\/staging\/?p=6277"},"modified":"2026-04-04T17:41:43","modified_gmt":"2026-04-04T14:41:43","slug":"anti-jo-1","status":"publish","type":"post","link":"https:\/\/mikrobiologikolamia.gr\/staging\/anti-jo-1\/","title":{"rendered":"\u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-Jo-1: \u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9, \u03c0\u03cc\u03c4\u03b5 \u03b6\u03b7\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9, \u03c0\u03ce\u03c2 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u2013 \u03a6\u03b9\u03bb\u03b9\u03ba\u03cc\u03c2 \u039f\u03b4\u03b7\u03b3\u03cc\u03c2"},"content":{"rendered":"<article style=\"font-family: system-ui,-apple-system,Segoe UI,Roboto,Helvetica,Arial,sans-serif; line-height: 1.7; color: #111827; max-width: 900px; margin: 0 auto; padding: 16px;\">\n<h1 style=\"font-size: 44px; line-height: 1.15; font-weight: 800; margin: 0 0 14px; color: #111827;\">\u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-Jo-1 \u2013 \u03a6\u03b9\u03bb\u03b9\u03ba\u03cc\u03c2 \u039f\u03b4\u03b7\u03b3\u03cc\u03c2<\/h1>\n<div style=\"margin: 10px 0 12px; font-size: 13px; color: #6b7280;\">\u0394\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7:<br \/>\n<time datetime=\"2025-09-29\">29 \u03a3\u03b5\u03c0\u03c4\u03b5\u03bc\u03b2\u03c1\u03af\u03bf\u03c5 2025<\/time><br \/>\n\u2022 \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7:<br \/>\n<time datetime=\"2026-04-04\">4 \u0391\u03c0\u03c1\u03b9\u03bb\u03af\u03bf\u03c5 2026<\/time><\/div>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0 18px;\"><strong>\u03a3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7 \u03c0\u03b5\u03c1\u03af\u03bb\u03b7\u03c8\u03b7:<\/strong><br \/>\n\u03a4\u03b1 <strong>\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-Jo-1<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bc\u03b5 \u03c4\u03bf<br \/>\n<strong>\u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd<\/strong>, \u03c4\u03b9\u03c2 <strong>\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b5\u03c2<\/strong> \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bc\u03b5<br \/>\n<strong>\u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1<\/strong>. \u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b4\u03b5\u03bd \u03bc\u03c0\u03b1\u03af\u03bd\u03b5\u03b9 \u03c9\u03c2 \u03c0\u03c1\u03bf\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c3\u03b5 \u03cc\u03bb\u03bf\u03c5\u03c2, \u03b1\u03bb\u03bb\u03ac \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd<br \/>\n\u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1, \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 CK, \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1, \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03bf\u03c2 \u03be\u03b7\u03c1\u03cc\u03c2 \u03b2\u03ae\u03c7\u03b1\u03c2, Raynaud, \u03b1\u03c1\u03b8\u03c1\u03b1\u03bb\u03b3\u03af\u03b5\u03c2 \u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1\u03c2.<br \/>\n\u0388\u03bd\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 <strong>\u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03b5\u03af \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/strong>, \u03b1\u03bb\u03bb\u03ac \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9 \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9<br \/>\n\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7.<\/div>\n<nav id=\"toc\" style=\"background: #f9fafb; border: 1px solid #e5e7eb; border-radius: 14px; padding: 16px; margin: 12px 0 16px;\" aria-label=\"\u03a0\u03af\u03bd\u03b1\u03ba\u03b1\u03c2 \u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd\"><strong>\u03a0\u03af\u03bd\u03b1\u03ba\u03b1\u03c2 \u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd<\/strong><\/p>\n<ol style=\"margin: 8px 0 0 18px; padding: 0;\">\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section1\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-Jo-1;<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section2\">\u03a0\u03cc\u03c4\u03b5 \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section3\">\u03a3\u03b5 \u03c0\u03bf\u03b9\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section4\">\u039c\u03b5 \u03c0\u03bf\u03b9\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section5\">\u03a0\u03bf\u03b9\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b2\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c8\u03af\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section6\">\u03a0\u03ce\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b9 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section7\">\u03a0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section8\">\u03a0\u03ce\u03c2 \u03b4\u03b9\u03b1\u03b2\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section9\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti-Jo-1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section10\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03ae \u03bf\u03c1\u03b9\u03b1\u03ba\u03cc anti-Jo-1<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section11\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b6\u03b7\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b1\u03b6\u03af<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section12\">\u0397 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5 anti-Jo-1 \u03b3\u03b9\u03b1 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03c5\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section13\">\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section14\">\u03a0\u03cc\u03c4\u03b5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section15\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b5\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section16\">\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/a><\/li>\n<li><a style=\"color: #dc2626; text-decoration: none;\" href=\"#section17\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd &amp; \u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/a><\/li>\n<\/ol>\n<\/nav>\n<hr style=\"border: 0; border-top: 2px solid #d1d5db; margin: 0 0 26px;\" \/>\n<p><!-- ==================== SECTION 1 ==================== --><\/p>\n<section id=\"section1\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">1<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-Jo-1;<\/span><\/h2>\n<p>\u03a4\u03b1 <strong>\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-Jo-1<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c4\u03bf\u03c7\u03b5\u03cd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd<br \/>\n<strong>\u03b9\u03c3\u03c4\u03b9\u03b4\u03c5\u03bb\u03bf-tRNA \u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03ac\u03c3\u03b7<\/strong>, \u03ad\u03bd\u03b1 \u03ad\u03bd\u03b6\u03c5\u03bc\u03bf \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03ce\u03bd \u03bc\u03ad\u03c3\u03b1 \u03c3\u03c4\u03bf \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03bf.<br \/>\n\u0391\u03bd\u03ae\u03ba\u03bf\u03c5\u03bd \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c4\u03c9\u03bd <strong>myositis-specific antibodies<\/strong> \u03ba\u03b1\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03c0\u03b9\u03bf \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03c5\u03cc\u03bc\u03b5\u03bd\u03bf<br \/>\n\u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03c4\u03c9\u03bd <strong>\u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd<\/strong>. \u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7, \u03cc\u03c4\u03b1\u03bd \u03bf \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03b6\u03b7\u03c4\u03ac anti-Jo-1,<br \/>\n\u03c0\u03c1\u03bf\u03c3\u03c0\u03b1\u03b8\u03b5\u03af \u03bd\u03b1 \u03b1\u03c0\u03b1\u03bd\u03c4\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c4\u03bf \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1 \u03b1\u03bd \u03c0\u03af\u03c3\u03c9 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b9\u03b1 <strong>\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7\u03c2 \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1<\/strong>,<br \/>\n\u03ad\u03bd\u03b1 <strong>\u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd<\/strong> \u03ae \u03bc\u03b9\u03b1 \u03bc\u03bf\u03c1\u03c6\u03ae \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5\u03c2 \u03bc\u03cd\u03b5\u03c2 \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2,<br \/>\n\u03c4\u03b9\u03c2 \u03b1\u03c1\u03b8\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1.<\/p>\n<p>\u03a4\u03bf anti-Jo-1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u00ab\u03ad\u03bd\u03b1 \u03b1\u03ba\u03cc\u03bc\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf\u00bb. \u0388\u03c7\u03b5\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b2\u03ac\u03c1\u03bf\u03c2 \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03ad\u03bd\u03b1 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf<br \/>\n\u03c6\u03b1\u03b9\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf \u03bd\u03cc\u03c3\u03bf\u03c5. \u03a3\u03b5 \u03b1\u03c1\u03ba\u03b5\u03c4\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c4\u03bf \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1 \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc <strong>\u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1<\/strong>, <strong>\u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 CK<\/strong>,<br \/>\n<strong>\u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1<\/strong>, <strong>\u03b1\u03c1\u03b8\u03c1\u03b1\u03bb\u03b3\u03af\u03b5\u03c2 \u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1<\/strong>, <strong>Raynaud<\/strong> \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03bb\u03b5\u03b3\u03cc\u03bc\u03b5\u03bd\u03b1<br \/>\n<strong>\u00ab\u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03ba\u03ac \u03c7\u03ad\u03c1\u03b9\u03b1\u00bb<\/strong>, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03c5\u03c0\u03b5\u03c1\u03ba\u03b5\u03c1\u03ac\u03c4\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c7\u03cd\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c4\u03b1 \u03b4\u03ac\u03ba\u03c4\u03c5\u03bb\u03b1. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc\u03bd \u03c4\u03bf\u03bd \u03bb\u03cc\u03b3\u03bf \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03be\u03af\u03b1 \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf<br \/>\n\u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c3\u03c9\u03c3\u03c4\u03ae \u03ba\u03b1\u03c4\u03b5\u03cd\u03b8\u03c5\u03bd\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5.<\/p>\n<p>\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03cc\u03c4\u03b9 \u03c4\u03bf anti-Jo-1 \u03b4\u03b5\u03bd \u03b4\u03b9\u03b1\u03b2\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03bf\u03ba\u03bf\u03bc\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03bf \u03c5\u03c0\u03cc\u03bb\u03bf\u03b9\u03c0\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc. \u0388\u03bd\u03b1\u03c2 \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9<br \/>\n\u03bc\u03c5\u03ca\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c7\u03c9\u03c1\u03af\u03c2 \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 anti-Jo-1, \u03b5\u03bd\u03ce \u03ac\u03bb\u03bb\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti-Jo-1 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03b5\u03b9 \u03c0\u03c1\u03ce\u03c4\u03b1 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae<br \/>\n\u03ba\u03b1\u03b9 \u03b1\u03c1\u03b3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1. \u0391\u03c5\u03c4\u03cc \u03b5\u03be\u03b7\u03b3\u03b5\u03af \u03b3\u03b9\u03b1\u03c4\u03af \u03bf \u03c3\u03c9\u03c3\u03c4\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 <strong>\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7, \u03bc\u03c5\u03ca\u03ba\u03ac \u03ad\u03bd\u03b6\u03c5\u03bc\u03b1,<br \/>\n\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b5\u03c5\u03c1\u03cd\u03c4\u03b5\u03c1\u03bf \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb<\/strong>.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 14px 0 0;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf \u03c3\u03b7\u03bc\u03b5\u03af\u03bf:<\/strong><br \/>\n\u03a4\u03bf anti-Jo-1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03b5\u03bd\u03b9\u03ba\u03bf\u03cd check-up. \u0391\u03be\u03af\u03b6\u03b5\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03b3\u03b9\u03b1 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1,<br \/>\n\u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd \u03ae \u03b1\u03bd\u03b5\u03be\u03ae\u03b3\u03b7\u03c4\u03b7 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 2 ==================== --><\/p>\n<section id=\"section2\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">2<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03cc\u03c4\u03b5 \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/span><\/h2>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03bf \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03ae\u03c3\u03b5\u03b9 \u03b1\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ae \u03c4\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b1\u03b9\u03c1\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u03bc\u03b5<br \/>\n<strong>\u03b9\u03b4\u03b9\u03bf\u03c0\u03b1\u03b8\u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7 \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1<\/strong> \u03ae \u03bc\u03b5 <strong>\u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd<\/strong>. \u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c0\u03c1\u03ce\u03c4\u03b7<br \/>\n\u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03b1\u03c3\u03b1\u03c6\u03ae \u03b5\u03bd\u03bf\u03c7\u03bb\u03ae\u03bc\u03b1\u03c4\u03b1. \u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03bc\u03c0\u03b1\u03af\u03bd\u03b5\u03b9 \u03c0\u03b9\u03bf \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03cc\u03c0\u03c9\u03c2<br \/>\n<strong>\u03b5\u03b3\u03b3\u03cd\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1<\/strong>, <strong>\u03b1\u03bd\u03b5\u03be\u03ae\u03b3\u03b7\u03c4\u03b1 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 CK<\/strong>, <strong>\u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1 \u03bc\u03b5 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7\u03c2 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1\u03c2<\/strong>,<br \/>\n<strong>\u03b1\u03c1\u03b8\u03c1\u03b1\u03bb\u03b3\u03af\u03b5\u03c2<\/strong>, <strong>Raynaud<\/strong>, \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bb\u03bb\u03bf\u03b9\u03ce\u03c3\u03b5\u03b9\u03c2 \u03ae \u03b3\u03b5\u03bd\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ae \u03bc\u03b5 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1.<\/p>\n<p>\u03a0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03c6\u03bf\u03c1\u03ad\u03c2 \u03c4\u03bf anti-Jo-1 \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03b7 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03b5\u03b9 \u03b1\u03c0\u03cc <strong>\u03b1\u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/strong>.<br \/>\n\u0393\u03b9\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03b5\u03b9\u03b3\u03bc\u03b1, \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c0\u03bf\u03bd\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bc\u03b7\u03c1\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03ce\u03bc\u03bf\u03c5\u03c2, \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03bd\u03b1 \u03c3\u03b7\u03ba\u03c9\u03b8\u03b5\u03af \u03b1\u03c0\u03cc \u03ba\u03b1\u03c1\u03ad\u03ba\u03bb\u03b1<br \/>\n\u03ae \u03bd\u03b1 \u03b1\u03bd\u03b5\u03b2\u03b5\u03af \u03c3\u03ba\u03ac\u03bb\u03b5\u03c2, \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1 \u03bd\u03b1 \u03c6\u03b1\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b1 \u03bc\u03c5\u03ca\u03ba\u03ac \u03ad\u03bd\u03b6\u03c5\u03bc\u03b1. \u03a3\u03b5 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2, \u03c4\u03bf \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03bc\u03c5\u03c2 \u03b1\u03bb\u03bb\u03ac \u03bf<br \/>\n\u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1\u03c2: \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03bf\u03c2 \u03be\u03b7\u03c1\u03cc\u03c2 \u03b2\u03ae\u03c7\u03b1\u03c2, \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7 \u03ae \u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae HRCT. \u03a3\u03b5 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c4\u03bf anti-Jo-1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bd\u03bf\u03af\u03be\u03b5\u03b9 \u03c4\u03bf\u03bd<br \/>\n\u03b4\u03c1\u03cc\u03bc\u03bf \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b7 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7.<\/p>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b8\u03ad\u03c3\u03b7 \u03cc\u03c4\u03b1\u03bd \u03bf \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03b8\u03ad\u03bb\u03b5\u03b9 \u03bd\u03b1 \u03be\u03b5\u03c7\u03c9\u03c1\u03af\u03c3\u03b5\u03b9 \u03bc\u03b9\u03b1 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7 \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 \u03b1\u03c0\u03cc \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b1\u03b9\u03c4\u03af\u03b5\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1\u03c2,<br \/>\n\u03cc\u03c0\u03c9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1, \u03b5\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03b1\u03af\u03c4\u03b9\u03b1, \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2 \u03ae \u03bc\u03b7 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b5\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ad\u03c2 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2.<br \/>\n\u039c\u03b5 \u03b1\u03c0\u03bb\u03ac \u03bb\u03cc\u03b3\u03b9\u03b1, \u03c4\u03bf anti-Jo-1 \u03b4\u03b5\u03bd \u03b1\u03c0\u03b1\u03bd\u03c4\u03ac \u03bc\u03cc\u03bd\u03bf \u00ab\u03bd\u03b1\u03b9 \u03ae \u03cc\u03c7\u03b9\u00bb, \u03b1\u03bb\u03bb\u03ac \u03b2\u03bf\u03b7\u03b8\u03ac \u03bd\u03b1 \u03bc\u03c0\u03b5\u03b9 \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c3\u03c4\u03bf \u03c3\u03c9\u03c3\u03c4\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 3 ==================== --><\/p>\n<section id=\"section3\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">3<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03b5 \u03c0\u03bf\u03b9\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1<\/span><\/h2>\n<p>\u0397 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c4\u03bf <strong>\u03c0\u03c1\u03bf-\u03c4\u03b5\u03c3\u03c4 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b5\u03bd\u03b4\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03bf<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03ae\u03b4\u03b7 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc.<br \/>\n\u0394\u03b7\u03bb\u03b1\u03b4\u03ae, \u03cc\u03c4\u03b1\u03bd \u03bf \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03b4\u03b5\u03bd \u03c8\u03ac\u03c7\u03bd\u03b5\u03b9 \u03c3\u03c4\u03b1 \u03c4\u03c5\u03c6\u03bb\u03ac, \u03b1\u03bb\u03bb\u03ac \u03ad\u03c7\u03b5\u03b9 \u03bc\u03c0\u03c1\u03bf\u03c3\u03c4\u03ac \u03c4\u03bf\u03c5 \u03ad\u03bd\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1. \u03a3\u03b5 \u03b1\u03c5\u03c4\u03bf\u03cd\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2<br \/>\n\u03c4\u03bf anti-Jo-1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7\u03c2.<\/p>\n<p>\u0395\u03b9\u03b4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03b1, \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03b5:<\/p>\n<ul style=\"padding-left: 18px; margin: 0 0 12px;\">\n<li>\u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 <strong>\u03b5\u03b3\u03b3\u03cd\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1<\/strong> \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b1 \u03bc\u03c5\u03ca\u03ba\u03ac \u03ad\u03bd\u03b6\u03c5\u03bc\u03b1,<\/li>\n<li>\u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 <strong>\u03b1\u03bd\u03b5\u03be\u03ae\u03b3\u03b7\u03c4\u03b7 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1<\/strong>, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b5\u03be\u03c9\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ac \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1,<\/li>\n<li>\u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 <strong>\u03b1\u03c1\u03b8\u03c1\u03b1\u03bb\u03b3\u03af\u03b5\u03c2\/\u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1<\/strong> \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b5\u03be\u03b7\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b5\u03c0\u03b1\u03c1\u03ba\u03ce\u03c2 \u03b1\u03c0\u03cc \u03ac\u03bb\u03bb\u03bf \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1,<\/li>\n<li>\u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 <strong>Raynaud<\/strong>, \u00ab\u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03ba\u03ac \u03c7\u03ad\u03c1\u03b9\u03b1\u00bb \u03ae \u03b5\u03c0\u03b9\u03ba\u03b1\u03bb\u03c5\u03c0\u03c4\u03cc\u03bc\u03b5\u03bd\u03b1 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03cd \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf\u03c5,<\/li>\n<li>\u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bf\u03c0\u03bf\u03af\u03bf\u03c5\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03ae\u03b4\u03b7 \u03c4\u03b5\u03b8\u03b5\u03af \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 <strong>\u03c4\u03b1\u03be\u03b9\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7 \u03c5\u03c0\u03bf\u03c4\u03cd\u03c0\u03bf\u03c5<\/strong>,<\/li>\n<li>\u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03bf\u03c5 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03ba\u03c4\u03b9\u03bc\u03b7\u03b8\u03b5\u03af \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03ae \u03ae\u03b4\u03b7 \u03b5\u03b3\u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b7\u03bc\u03ad\u03bd\u03b7 <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae<\/strong>.<\/li>\n<\/ul>\n<p>\u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03c0\u03bf\u03bb\u03cd \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03b1\u03c6\u03ae \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ae \u03bc\u03cc\u03bd\u03bf \u03ba\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03ad\u03bd\u03b1<br \/>\n\u03b3\u03b5\u03bd\u03b9\u03ba\u03cc \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf screening. \u03a3\u03c4\u03b1 \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1, \u03b7 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b5\u03c1\u03ce\u03c4\u03b7\u03c3\u03b7 \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1:<br \/>\n<strong>\u00ab\u03a4\u03b9 \u03c5\u03c0\u03bf\u03c8\u03b9\u03ac\u03b6\u03bf\u03bc\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac;\u00bb<\/strong> \u0391\u03bd \u03b1\u03c5\u03c4\u03ae \u03b7 \u03b5\u03c1\u03ce\u03c4\u03b7\u03c3\u03b7 \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c0\u03b1\u03bd\u03c4\u03b7\u03b8\u03b5\u03af, \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b5\u03cd\u03ba\u03bf\u03bb\u03bf \u03bd\u03b1 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03b7\u03b8\u03b5\u03af \u03c3\u03cd\u03b3\u03c7\u03c5\u03c3\u03b7 \u03c0\u03b1\u03c1\u03ac \u03bd\u03b1<br \/>\n\u03c0\u03c1\u03bf\u03ba\u03cd\u03c8\u03b5\u03b9 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 4 ==================== --><\/p>\n<section id=\"section4\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">4<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u039c\u03b5 \u03c0\u03bf\u03b9\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9<\/span><\/h2>\n<p>\u03a4\u03bf anti-Jo-1 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03c9\u03c4\u03af\u03c3\u03c4\u03c9\u03c2 \u03bc\u03b5 \u03c4\u03bf <strong>\u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd<\/strong>, \u03ad\u03bd\u03b1 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03ae\u03ba\u03b5\u03b9 \u03c3\u03c4\u03bf<br \/>\n\u03b5\u03c5\u03c1\u03cd\u03c4\u03b5\u03c1\u03bf \u03c6\u03ac\u03c3\u03bc\u03b1 \u03c4\u03c9\u03bd <strong>\u03b9\u03b4\u03b9\u03bf\u03c0\u03b1\u03b8\u03ce\u03bd \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03c9\u03b4\u03ce\u03bd \u03bc\u03c5\u03bf\u03c0\u03b1\u03b8\u03b5\u03b9\u03ce\u03bd<\/strong>. \u03a4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03af\u03b4\u03b9\u03bf \u03c4\u03c1\u03cc\u03c0\u03bf \u03c3\u03b5 \u03cc\u03bb\u03bf\u03c5\u03c2.<br \/>\n\u03a3\u03b5 \u03bc\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd\u03c2 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03b5\u03af \u03b7 \u03bc\u03c5\u03ca\u03ba\u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03c3\u03b5 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03b7 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1, \u03b5\u03bd\u03ce \u03c3\u03b5 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03b7 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1 \u03ae \u03c4\u03b1 \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac\/\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ac \u03c3\u03b7\u03bc\u03b5\u03af\u03b1.<br \/>\n\u0391\u03c5\u03c4\u03ae \u03b1\u03ba\u03c1\u03b9\u03b2\u03ce\u03c2 \u03b7 \u03b5\u03c4\u03b5\u03c1\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03b5\u03be\u03b7\u03b3\u03b5\u03af \u03b3\u03b9\u03b1\u03c4\u03af \u03c4\u03bf anti-Jo-1 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1.<\/p>\n<p>\u03a4\u03bf \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b1\u03bd\u03c4\u03b7\u03b8\u03b5\u03af \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5:<\/p>\n<ul style=\"padding-left: 18px; margin: 0 0 12px;\">\n<li><strong>\u03c0\u03bf\u03bb\u03c5\u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1<\/strong>,<\/li>\n<li><strong>\u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03bf\u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1<\/strong>,<\/li>\n<li><strong>\u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd<\/strong>,<\/li>\n<li><strong>overlap \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03b1<\/strong> \u03bc\u03b5 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03b1\u03c0\u03cc \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03cc\u03c2 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1,<\/li>\n<li>\u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ac \u03c3\u03b5 \u03ac\u03bb\u03bb\u03b1 \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03b1 \u03cc\u03c0\u03bf\u03c5 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c4\u03b7 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03bf\u03c3\u03af\u03b1.<\/li>\n<\/ul>\n<p>\u03a3\u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03ac\u03be\u03b7 \u03cc\u03bc\u03c9\u03c2, \u03cc\u03c4\u03b1\u03bd \u03ad\u03bd\u03b1\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c3\u03b5 anti-Jo-1 \u03ba\u03b1\u03b9 \u03ad\u03c7\u03b5\u03b9 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1,<br \/>\n\u03c4\u03bf \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u00ab\u03ad\u03c7\u03b5\u03b9 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1;\u00bb, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9<br \/>\n<strong>\u00ab\u03ad\u03c7\u03b5\u03b9 \u03ae \u03b8\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03b5\u03b9 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1;\u00bb<\/strong>. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc\u03bd \u03c4\u03bf\u03bd \u03bb\u03cc\u03b3\u03bf \u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c3\u03c5\u03c7\u03bd\u03ac \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc<br \/>\n\u03ba\u03bf\u03bc\u03bc\u03ac\u03c4\u03b9 \u03c4\u03bf\u03c5 work-up \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03ad\u03bd\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin-top: 14px;\"><strong>\u03a3\u03c5\u03c7\u03bd\u03cc \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03bb\u03ac\u03b8\u03bf\u03c2:<\/strong><br \/>\n\u03bd\u03b1 \u03b4\u03b9\u03b1\u03b2\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf anti-Jo-1 \u03bc\u03cc\u03bd\u03bf \u03c9\u03c2 \u00ab\u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1\u03c2\u00bb \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c5\u03c0\u03bf\u03c4\u03b9\u03bc\u03ac\u03c4\u03b1\u03b9 \u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1<br \/>\n\u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae\u03c2.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 5 ==================== --><\/p>\n<section id=\"section5\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">5<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03bf\u03b9\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b2\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c8\u03af\u03b1<\/span><\/h2>\n<p>\u0397 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03b3\u03b9\u03b1 anti-Jo-1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b3\u03b5\u03bd\u03bd\u03b9\u03ad\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03c0\u03cc <strong>\u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/strong>, \u03cc\u03c7\u03b9 \u03b1\u03c0\u03cc \u03ad\u03bd\u03b1 \u03bc\u03cc\u03bd\u03bf \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1.<br \/>\n\u03a4\u03b1 \u03c0\u03b9\u03bf \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 \u03b5\u03be\u03ae\u03c2:<\/p>\n<ul style=\"padding-left: 18px; margin: 0 0 12px;\">\n<li><strong>\u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1<\/strong>, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03ce\u03bc\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bc\u03b7\u03c1\u03bf\u03cd\u03c2,<\/li>\n<li><strong>\u03ba\u03cc\u03c0\u03c9\u03c3\u03b7<\/strong> \u03ba\u03b1\u03b9 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03b5 \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ad\u03c2 \u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03b9\u03c2,<\/li>\n<li><strong>\u03bc\u03c5\u03b1\u03bb\u03b3\u03af\u03b5\u03c2<\/strong> \u03ae \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u00ab\u03b2\u03b1\u03c1\u03b9\u03ce\u03bd\u00bb \u03bc\u03c5\u03ce\u03bd,<\/li>\n<li><strong>\u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7<\/strong> \u03ae \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03bf\u03c2 \u03be\u03b7\u03c1\u03cc\u03c2 \u03b2\u03ae\u03c7\u03b1\u03c2,<\/li>\n<li><strong>\u03b1\u03c1\u03b8\u03c1\u03b1\u03bb\u03b3\u03af\u03b5\u03c2 \u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1<\/strong>,<\/li>\n<li><strong>\u03c6\u03b1\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf Raynaud<\/strong>,<\/li>\n<li><strong>\u00ab\u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03ba\u03ac \u03c7\u03ad\u03c1\u03b9\u03b1\u00bb<\/strong> \u03bc\u03b5 \u03c4\u03c1\u03b1\u03c7\u03b9\u03ac, \u03c3\u03ba\u03b1\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c0\u03b9\u03b4\u03b5\u03c1\u03bc\u03af\u03b4\u03b1 \u03c3\u03c4\u03b9\u03c2 \u03c0\u03b1\u03bb\u03ac\u03bc\u03b5\u03c2 \u03ae \u03c3\u03c4\u03b1 \u03c0\u03bb\u03ac\u03b3\u03b9\u03b1 \u03c4\u03c9\u03bd \u03b4\u03b1\u03ba\u03c4\u03cd\u03bb\u03c9\u03bd,<\/li>\n<li><strong>\u03b1\u03bd\u03b5\u03be\u03ae\u03b3\u03b7\u03c4\u03b1 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 CK, LDH, AST \u03ae ALT<\/strong> \u03c7\u03c9\u03c1\u03af\u03c2 \u03ac\u03bb\u03bb\u03b7 \u03c0\u03c1\u03bf\u03c6\u03b1\u03bd\u03ae \u03b5\u03be\u03ae\u03b3\u03b7\u03c3\u03b7.<\/li>\n<\/ul>\n<p>\u0394\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf \u03bd\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03cc\u03bb\u03b1 \u03bc\u03b1\u03b6\u03af. \u039a\u03ac\u03c0\u03bf\u03b9\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03be\u03b5\u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03b9 \u03bc\u03b5 \u03ba\u03c5\u03c1\u03af\u03b1\u03c1\u03c7\u03bf \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03b1 \u03bc\u03c5\u03ca\u03ba\u03ac<br \/>\n\u03b5\u03bd\u03bf\u03c7\u03bb\u03ae\u03bc\u03b1\u03c4\u03b1. \u0386\u03bb\u03bb\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03b5\u03b9 \u03c0\u03c1\u03ce\u03c4\u03b1 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b1\u03c1\u03b3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae. \u0391\u03c5\u03c4\u03ae \u03b7 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae \u03b1\u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03c1\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9<br \/>\n\u03b2\u03b1\u03c3\u03b9\u03ba\u03cc\u03c2 \u03bb\u03cc\u03b3\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b5\u03c0\u03b1\u03b3\u03c1\u03cd\u03c0\u03bd\u03b7\u03c3\u03b7 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03cd\u03c0\u03bf\u03c0\u03c4\u03bf\u03c2 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ce\u03bd \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd.<\/p>\n<p>\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03bc\u03bf\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u00ab\u03b4\u03b9\u03ac\u03c3\u03c0\u03b1\u03c1\u03c4\u03b1\u00bb \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b4\u03af\u03bd\u03bf\u03c5\u03bd \u03b1\u03bc\u03ad\u03c3\u03c9\u03c2 \u03bc\u03b9\u03b1 \u03c0\u03c1\u03bf\u03c6\u03b1\u03bd\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7.<br \/>\n\u0397 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c3\u03ba\u03ad\u03c8\u03b7 \u03c4\u03cc\u03c4\u03b5 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1, \u03b1\u03bb\u03bb\u03ac \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b6\u03b7\u03c4\u03ac \u03c4\u03bf \u03b5\u03bd\u03b9\u03b1\u03af\u03bf \u03bd\u03ae\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03c4\u03b1 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03b9:<br \/>\n\u03bc\u03c5\u03c2, \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1\u03c2, \u03b1\u03c1\u03b8\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2, \u03b1\u03b3\u03b3\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 6 ==================== --><\/p>\n<section id=\"section6\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">6<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03ce\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b9 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9<\/span><\/h2>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 <strong>\u03b1\u03c0\u03bb\u03ae \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1<\/strong> \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03bb\u03cd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 <strong>\u03bf\u03c1\u03cc \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2<\/strong>.<br \/>\n\u0391\u03c0\u03cc \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c0\u03bb\u03b5\u03c5\u03c1\u03ac\u03c2, \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03bc\u03b5 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03b8\u03cc\u03b4\u03bf\u03c5\u03c2,<br \/>\n\u03cc\u03c0\u03c9\u03c2 <strong>ELISA<\/strong>, <strong>line blot \/ immunoblot<\/strong> \u03ae \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c0\u03bb\u03b1\u03c4\u03c6\u03cc\u03c1\u03bc\u03b5\u03c2 \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf.<br \/>\n\u0393\u03b9\u03b1 \u03c4\u03bf\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03af\u03b4\u03b9\u03b1 \u03cc\u03c0\u03c9\u03c2 \u03c3\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03ba\u03bf\u03b9\u03bd\u03ae \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1: \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03b1\u03c0\u03cc \u03c6\u03bb\u03ad\u03b2\u03b1 \u03c4\u03bf\u03c5 \u03c7\u03b5\u03c1\u03b9\u03bf\u03cd, \u03c3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7 \u03bb\u03ae\u03c8\u03b7, \u03c7\u03c9\u03c1\u03af\u03c2 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03c4\u03b1\u03bb\u03b1\u03b9\u03c0\u03c9\u03c1\u03af\u03b1.<\/p>\n<p>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03b1\u03c0\u03cc \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03c3\u03b5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03cc\u03c3\u03bf \u03c4\u03bf \u03c0\u03ce\u03c2 \u03b8\u03b1 \u03bb\u03b7\u03c6\u03b8\u03b5\u03af \u03c4\u03bf \u03b1\u03af\u03bc\u03b1, \u03b1\u03bb\u03bb\u03ac<br \/>\n<strong>\u03bf \u03c4\u03c1\u03cc\u03c0\u03bf\u03c2 \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c0\u03ce\u03c2 \u03b8\u03b1 \u03b5\u03ba\u03c6\u03c1\u03b1\u03c3\u03c4\u03b5\u03af \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/strong>. \u039c\u03b5\u03c1\u03b9\u03ba\u03ac \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03b1 \u03b4\u03af\u03bd\u03bf\u03c5\u03bd \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7 \u03c9\u03c2<br \/>\n\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc\/\u03bf\u03c1\u03b9\u03b1\u03ba\u03cc\/\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc, \u03ac\u03bb\u03bb\u03b1 \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03bf\u03c5\u03bd \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b1\u03c0\u03cc \u03bc\u03bf\u03bd\u03ac\u03b4\u03b5\u03c2 \u03ba\u03b1\u03b9 cut-off. \u0395\u03c0\u03b5\u03b9\u03b4\u03ae \u03bf\u03b9 \u03c0\u03bb\u03b1\u03c4\u03c6\u03cc\u03c1\u03bc\u03b5\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03bb\u03cd\u03c4\u03c9\u03c2 \u03af\u03b4\u03b9\u03b5\u03c2,<br \/>\n\u03b7 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b1 <strong>\u03cc\u03c1\u03b9\u03b1 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03bf\u03c5<\/strong>.<\/p>\n<p>\u03a3\u03b5 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2, \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc \u03b7 \u03b5\u03c0\u03b1\u03bd\u03ac\u03bb\u03b7\u03c8\u03b7 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf <strong>\u03af\u03b4\u03b9\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03ae \u03c3\u03c4\u03b7\u03bd \u03af\u03b4\u03b9\u03b1 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf<\/strong>,<br \/>\n\u03ce\u03c3\u03c4\u03b5 \u03bf\u03b9 \u03c3\u03c5\u03b3\u03ba\u03c1\u03af\u03c3\u03b5\u03b9\u03c2 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c3\u03bf \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b1\u03c3\u03c6\u03b1\u03bb\u03b5\u03af\u03c2. \u0391\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ad\u03bd\u03b1 \u03ac\u03bb\u03bb\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03bb\u03ac\u03b8\u03bf\u03c2,<br \/>\n\u03b1\u03bb\u03bb\u03ac \u03cc\u03c4\u03b9 \u03b7 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ac \u03bd\u03b1 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b1 \u03bf\u03b9 \u03bc\u03b9\u03ba\u03c1\u03ad\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 7 ==================== --><\/p>\n<section id=\"section7\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">7<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1<\/span><\/h2>\n<p>\u0393\u03b9\u03b1 \u03c4\u03bf <strong>anti-Jo-1<\/strong> \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 <strong>\u03b4\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1<\/strong>. \u0397 \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9<br \/>\n\u03cc\u03c0\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b5\u03ba\u03c4\u03cc\u03c2 \u03b1\u03bd \u03bf \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03b6\u03b7\u03c4\u03ae\u03c3\u03b5\u03b9 \u03c4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b1\u03bd\u03b1\u03bb\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c0\u03b1\u03b9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2.<br \/>\n\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7, \u03bf \u03c0\u03b9\u03bf \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf\u03c2 \u03ba\u03b1\u03bd\u03cc\u03bd\u03b1\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1 \u03bc\u03b7\u03bd \u03b5\u03c3\u03c4\u03b9\u03ac\u03b6\u03b5\u03c4\u03b5 \u03c4\u03cc\u03c3\u03bf \u03c3\u03c4\u03b7 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1 \u03cc\u03c3\u03bf \u03c3\u03c4\u03b7 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03b3\u03b9\u03b1\u03c4\u03c1\u03bf\u03cd.<\/p>\n<p>\u03a0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7, \u03ba\u03b1\u03bb\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03c4\u03b5:<\/p>\n<ul style=\"padding-left: 18px; margin: 0 0 12px;\">\n<li>\u03b1\u03bd \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 <strong>\u03ba\u03bf\u03c1\u03c4\u03b9\u03ba\u03bf\u03c3\u03c4\u03b5\u03c1\u03bf\u03b5\u03b9\u03b4\u03ae, \u03b1\u03bd\u03bf\u03c3\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ac \u03ae \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2<\/strong>,<\/li>\n<li>\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ae\u03b4\u03b7 \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc <strong>\u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1<\/strong>,<\/li>\n<li>\u03b1\u03bd \u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03b7\u03b3\u03b7\u03b8\u03b5\u03af \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b5\u03c2 <strong>\u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03af\u03b5\u03c2, \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2<\/strong> \u03ae \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7,<\/li>\n<li>\u03b1\u03bd \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 <strong>\u03c0\u03c1\u03ce\u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/strong> \u03ae \u03b3\u03b9\u03b1 <strong>\u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<\/strong>.<\/li>\n<\/ul>\n<p>\u0391\u03bd \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03bf\u03c5\u03bd \u03c4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b1 \u03ba\u03b1\u03b9 <strong>CK, LDH, AST, ALT, CRP, \u03a4\u039a\u0395, ANA \u03ae \u03c0\u03bb\u03ae\u03c1\u03b5\u03c2 \u03bc\u03c5\u03bf\u03c3\u03b9\u03c4\u03b9\u03b4\u03b9\u03ba\u03cc panel<\/strong>,<br \/>\n\u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03bf \u03bd\u03b1 \u03bb\u03b7\u03c6\u03b8\u03bf\u03cd\u03bd \u03bc\u03b1\u03b6\u03af. \u0388\u03c4\u03c3\u03b9 \u03bf \u03b8\u03b5\u03c1\u03ac\u03c0\u03c9\u03bd \u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03b8\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b9\u03b1 \u03b5\u03bd\u03b9\u03b1\u03af\u03b1 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c4\u03b7\u03c2 \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b8\u03b1 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1<br \/>\n\u03c3\u03c5\u03bd\u03b8\u03ad\u03c4\u03b5\u03b9 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c0\u03cc \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin-top: 14px;\"><strong>\u03a0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac:<\/strong><br \/>\n\u03b1\u03bd \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 follow-up, \u03ba\u03c1\u03b1\u03c4\u03ae\u03c3\u03c4\u03b5 \u03bc\u03b1\u03b6\u03af \u03c3\u03b1\u03c2 \u03c4\u03b1 \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1. \u0397 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c0\u03b1\u03bb\u03b9\u03bf\u03cd \u03ba\u03b1\u03b9 \u03bd\u03ad\u03bf\u03c5 \u03c4\u03af\u03c4\u03bb\u03bf\u03c5<br \/>\n\u03b2\u03bf\u03b7\u03b8\u03ac \u03c0\u03bf\u03bb\u03cd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc CK, \u03c3\u03c0\u03b9\u03c1\u03bf\u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c4\u03b7\u03c2 \u03af\u03b4\u03b9\u03b1\u03c2 \u03c0\u03b5\u03c1\u03b9\u03cc\u03b4\u03bf\u03c5.<\/div>\n<\/section>\n<p><!-- ==================== SECTION 8 ==================== --><\/p>\n<section id=\"section8\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">8<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03ce\u03c2 \u03b4\u03b9\u03b1\u03b2\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/span><\/h2>\n<p>\u03a4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b4\u03b9\u03b1\u03b2\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03b5 \u03c4\u03c1\u03af\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1: <strong>\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc<\/strong>, <strong>\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc<\/strong> \u03ba\u03b1\u03b9<br \/>\n<strong>\u03b4\u03b9\u03b1\u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc<\/strong>. \u03a4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03b1\u03c6\u03bf\u03c1\u03ac \u03b1\u03bd \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae, \u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03ae \u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03cc\u03c1\u03b9\u03b1 \u03c4\u03bf\u03c5<br \/>\n\u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03bf\u03c5. \u03a4\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03b1\u03c6\u03bf\u03c1\u03ac \u03b1\u03bd \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03c4\u03b9\u03ba\u03b5\u03b9\u03bc\u03b5\u03bd\u03b9\u03ba\u03ac \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03c4\u03b1\u03b9\u03c1\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u03bc\u03b5 \u03c4\u03b7<br \/>\n\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1. \u03a4\u03bf \u03b4\u03b9\u03b1\u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03b1\u03c6\u03bf\u03c1\u03ac \u03b1\u03bd \u03c4\u03bf \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03cc, \u03b1\u03bd \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9, \u03ba\u03b1\u03b9 \u03c0\u03ce\u03c2 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n<p>\u0388\u03bd\u03b1 <strong>\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc<\/strong> \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03b1\u03be\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03ae \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5.<br \/>\n\u0388\u03bd\u03b1 <strong>\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc<\/strong> \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03b5\u03b9 \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf, \u03b3\u03b9\u03b1\u03c4\u03af \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd \u03ae \u03ac\u03bb\u03bb\u03bf\u03b9 \u03c5\u03c0\u03bf\u03c4\u03cd\u03c0\u03bf\u03b9<br \/>\n\u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1\u03c2. \u0388\u03bd\u03b1 <strong>\u03bf\u03c1\u03b9\u03b1\u03ba\u03cc<\/strong> \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae, \u03b3\u03b9\u03b1\u03c4\u03af \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03bb\u03cd\u03bd\u03b5\u03b9 \u03c4\u03bf \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1.<br \/>\n\u0395\u03ba\u03b5\u03af \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c3\u03c5\u03bd\u03bf\u03b4\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 14px 0 10px;\">\u2194\ufe0f \u03a3\u03cd\u03c1\u03b5\u03c4\u03b5 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03c4\u03ae\u03bb\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03af\u03bd\u03b1\u03ba\u03b1<\/div>\n<div style=\"overflow-x: auto;\">\n<table style=\"width: 100%; border-collapse: collapse; min-width: 680px; font-size: 15px;\">\n<thead>\n<tr style=\"background: #f9fafb;\">\n<th style=\"text-align: left; border: 1px solid #e5e7eb; padding: 10px;\">\u0391\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/th>\n<th style=\"text-align: left; border: 1px solid #e5e7eb; padding: 10px;\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2<\/th>\n<th style=\"text-align: left; border: 1px solid #e5e7eb; padding: 10px;\">\u03a4\u03b9 \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>\u0391\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u0394\u03b5\u03bd \u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03b9 anti-Jo-1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03c6\u03b1\u03b9\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03b5\u03b9 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1 \u03ae \u03ac\u03bb\u03bb\u03bf anti-synthetase \u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1.<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u0391\u03bd \u03b7 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9, \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03c5\u03c1\u03cd\u03c4\u03b5\u03c1\u03bf panel \u03ba\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7.<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>\u039f\u03c1\u03b9\u03b1\u03ba\u03cc<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u039c\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03ce\u03bd\u03b5\u03b9 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7.<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u03a3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03b5\u03c0\u03b1\u03bd\u03ac\u03bb\u03b7\u03c8\u03b7 \u03ae panel \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03cc\u03c0\u03bf\u03c5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9.<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>\u0398\u03b5\u03c4\u03b9\u03ba\u03cc<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u03a5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03b9 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd \/ \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7 \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1.<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u0388\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bc\u03c5\u03ce\u03bd, \u03c0\u03bd\u03b5\u03c5\u03bc\u03cc\u03bd\u03c9\u03bd, ANA\/\u03bc\u03c5\u03bf\u03c3\u03b9\u03c4\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\/\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/section>\n<p><!-- ==================== SECTION 9 ==================== --><\/p>\n<section id=\"section9\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">9<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti-Jo-1<\/span><\/h2>\n<p>\u0388\u03bd\u03b1 <strong>\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti-Jo-1<\/strong> \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1 \u03bc\u03b5 \u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03c3\u03cd\u03bd\u03b4\u03b5\u03c3\u03b7 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03bf<br \/>\n<strong>\u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd<\/strong> \u03ba\u03b1\u03b9 \u03b3\u03b5\u03bd\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03bf \u03c6\u03ac\u03c3\u03bc\u03b1 \u03c4\u03c9\u03bd <strong>\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03c9\u03b4\u03ce\u03bd \u03bc\u03c5\u03bf\u03c0\u03b1\u03b8\u03b5\u03b9\u03ce\u03bd<\/strong>.<br \/>\n\u038c\u03bc\u03c9\u03c2 \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b1\u03c0\u03bf\u03ba\u03c4\u03ac \u03c4\u03bf \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03bd\u03cc\u03b7\u03bc\u03b1 \u03cc\u03c4\u03b1\u03bd \u00ab\u03ba\u03bf\u03c5\u03bc\u03c0\u03ce\u03bd\u03b5\u03b9\u00bb \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1. \u03a3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1,<br \/>\n\u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 CK \u03ba\u03b1\u03b9 \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1, \u03b7 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b1\u03c5\u03c4\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03be\u03b1\u03b9\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae. \u03a3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<br \/>\n\u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03c0\u03b9\u03bf \u03c0\u03c1\u03bf\u03c3\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03ac\u03b8\u03bc\u03b9\u03c3\u03b7.<\/p>\n<p>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac, \u03ad\u03bd\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03bf \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b6\u03b7\u03c4\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac:<\/p>\n<ul style=\"padding-left: 18px; margin: 0 0 12px;\">\n<li>\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 <strong>\u03b5\u03bd\u03b5\u03c1\u03b3\u03cc\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae<\/strong>,<\/li>\n<li>\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 <strong>\u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1<\/strong>, \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03b1\u03bd \u03c4\u03b1 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ae\u03c0\u03b9\u03b1,<\/li>\n<li>\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd <strong>\u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1, Raynaud, \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bb\u03bb\u03bf\u03b9\u03ce\u03c3\u03b5\u03b9\u03c2<\/strong> \u03ae overlap \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1,<\/li>\n<li>\u03b1\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c4\u03b1\u03be\u03b9\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2 \u03c3\u03b5 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf <strong>\u03c5\u03c0\u03cc\u03c4\u03c5\u03c0\u03bf \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1\u03c2<\/strong>.<\/li>\n<\/ul>\n<p>\u0395\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03bd\u03b1 \u03bc\u03b7\u03bd \u03c5\u03c0\u03b5\u03c1\u03b5\u03ba\u03c4\u03b9\u03bc\u03ac\u03c4\u03b1\u03b9 \u03c4\u03bf \u00ab\u03cd\u03c8\u03bf\u03c2\u00bb \u03c4\u03bf\u03c5 \u03c4\u03af\u03c4\u03bb\u03bf\u03c5 \u03c3\u03b1\u03bd \u03bd\u03b1 \u03ae\u03c4\u03b1\u03bd \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1\u03c2.<br \/>\n\u03a3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bf\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2 \u03c4\u03bf\u03c5 anti-Jo-1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03bd \u03c3\u03b5 \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf \u03b2\u03b1\u03b8\u03bc\u03cc \u03c4\u03b7\u03bd \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5,<br \/>\n\u03b1\u03bb\u03bb\u03ac \u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c4\u03bf <strong>\u03c3\u03cd\u03bd\u03bf\u03bb\u03bf<\/strong>:<br \/>\n\u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, CK, CRP\/\u03a4\u039a\u0395 \u03cc\u03c0\u03bf\u03c5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9, \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b5\u03c2 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1, HRCT \u03ba\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 10 ==================== --><\/p>\n<section id=\"section10\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">10<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03ae \u03bf\u03c1\u03b9\u03b1\u03ba\u03cc anti-Jo-1<\/span><\/h2>\n<p>\u0388\u03bd\u03b1 <strong>\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc anti-Jo-1<\/strong> <strong>\u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03b5\u03b9<\/strong> \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1 \u03bf\u03cd\u03c4\u03b5 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd.<br \/>\n\u0391\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03af\u03c3\u03c9\u03c2 \u03c4\u03bf \u03c0\u03b9\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c3\u03b7\u03bc\u03b5\u03af\u03bf \u03c0\u03bf\u03c5 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c4\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2. \u03a5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd, \u03cc\u03c0\u03c9\u03c2<br \/>\n<strong>anti-PL-7, anti-PL-12, anti-EJ, anti-OJ<\/strong>, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03bf\u03b9 \u03bc\u03c5\u03bf\u03c3\u03b9\u03c4\u03b9\u03b4\u03b9\u03ba\u03bf\u03af \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03bf\u03af \u03b5\u03bd\u03ce<br \/>\n\u03c4\u03bf anti-Jo-1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc. \u0395\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2, \u03ad\u03bd\u03b1 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2,<br \/>\n\u03cc\u03c7\u03b9 \u03ba\u03b1\u03c4\u2019 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ac.<\/p>\n<p>\u03a4\u03bf <strong>\u03bf\u03c1\u03b9\u03b1\u03ba\u03cc<\/strong> \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c0\u03b9\u03bf \u03b1\u03c0\u03b1\u03b9\u03c4\u03b7\u03c4\u03b9\u03ba\u03cc \u03c3\u03c4\u03b7\u03bd \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1. \u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03ae \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03bf\u03c5<br \/>\n\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bd\u03c4\u03b1\u03bd\u03b1\u03ba\u03bb\u03ac \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b9\u03b4\u03b9\u03b1\u03b9\u03c4\u03b5\u03c1\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03b8\u03cc\u03b4\u03bf\u03c5, \u03ae \u03b1\u03c0\u03bb\u03ce\u03c2 \u03bd\u03b1 \u03bc\u03b7\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c3\u03b1\u03c6\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1 \u03b1\u03bd \u03bb\u03b5\u03af\u03c0\u03b5\u03b9 \u03b7 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b7<br \/>\n\u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc\u03bd \u03c4\u03bf\u03bd \u03bb\u03cc\u03b3\u03bf \u03c4\u03b1 \u03bf\u03c1\u03b9\u03b1\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03bf\u03cd\u03bd \u03bf\u03cd\u03c4\u03b5 \u03c3\u03b5 \u03c0\u03b1\u03bd\u03b9\u03ba\u03cc \u03bf\u03cd\u03c4\u03b5 \u03c3\u03b5 \u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03b1 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03ac\u03c3\u03bc\u03b1\u03c4\u03b1.<\/p>\n<p>\u038c\u03c4\u03b1\u03bd \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03c0\u03b1\u03c1\u03ac \u03ad\u03bd\u03b1 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03ae \u03bf\u03c1\u03b9\u03b1\u03ba\u03cc anti-Jo-1, \u03bf \u03c3\u03c9\u03c3\u03c4\u03cc\u03c2 \u03b4\u03c1\u03cc\u03bc\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9:<\/p>\n<ul style=\"padding-left: 18px; margin: 0;\">\n<li>\u03b5\u03c0\u03ad\u03ba\u03c4\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 \u03c3\u03b5 <strong>\u03b5\u03c5\u03c1\u03cd\u03c4\u03b5\u03c1\u03bf panel \u03bc\u03c5\u03bf\u03c3\u03b9\u03c4\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd\/antisynthetase \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/strong>,<\/li>\n<li>\u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 <strong>CK, LDH, AST, ALT<\/strong>,<\/li>\n<li>\u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 <strong>\u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae<\/strong> \u03bc\u03b5 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b5\u03c2 \u03ae HRCT,<\/li>\n<li>\u03c3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7 \u03bc\u03b5 <strong>\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c3\u03c4\u03bf\u03bd \u03c7\u03c1\u03cc\u03bd\u03bf<\/strong>.<\/li>\n<\/ul>\n<\/section>\n<p><!-- ==================== SECTION 11 ==================== --><\/p>\n<section id=\"section11\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">11<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b6\u03b7\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b1\u03b6\u03af<\/span><\/h2>\n<p>\u03a4\u03bf anti-Jo-1 \u03c3\u03c7\u03b5\u03b4\u03cc\u03bd \u03c0\u03bf\u03c4\u03ad \u03b4\u03b5\u03bd \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5. \u039f \u03bb\u03cc\u03b3\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bb\u03cc\u03c2: \u03bf\u03b9 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf<br \/>\n\u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03c5\u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2. \u0393\u03b9\u03b1 \u03bd\u03b1 \u03b5\u03ba\u03c4\u03b9\u03bc\u03b7\u03b8\u03b5\u03af \u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1, \u03b7 \u03ad\u03ba\u03c4\u03b1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5,<br \/>\n\u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 14px 0 10px;\">\u2194\ufe0f \u03a3\u03cd\u03c1\u03b5\u03c4\u03b5 \u03bf\u03c1\u03b9\u03b6\u03cc\u03bd\u03c4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03c3\u03c4\u03ae\u03bb\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03af\u03bd\u03b1\u03ba\u03b1<\/div>\n<div style=\"overflow-x: auto;\">\n<table style=\"width: 100%; border-collapse: collapse; min-width: 760px; font-size: 15px;\">\n<thead>\n<tr style=\"background: #f9fafb;\">\n<th style=\"text-align: left; border: 1px solid #e5e7eb; padding: 10px;\">\u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/th>\n<th style=\"text-align: left; border: 1px solid #e5e7eb; padding: 10px;\">\u0393\u03b9\u03b1\u03c4\u03af \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9<\/th>\n<th style=\"text-align: left; border: 1px solid #e5e7eb; padding: 10px;\">\u03a4\u03b9 \u03c0\u03c1\u03bf\u03c3\u03b8\u03ad\u03c4\u03b5\u03b9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>CK<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u0392\u03b1\u03c3\u03b9\u03ba\u03cc\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03b2\u03bb\u03ac\u03b2\u03b7\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u03a5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03b9 \u03b5\u03bd\u03b5\u03c1\u03b3\u03cc \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1 \u03cc\u03c4\u03b1\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>LDH, AST, ALT<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u03a3\u03c5\u03bd\u03bf\u03b4\u03ad\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03b2\u03bb\u03ac\u03b2\u03b7\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u0392\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03c3\u03c4\u03b7\u03bd \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b2\u03b9\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>ANA<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u0393\u03b5\u03bd\u03b9\u03ba\u03cc\u03c2 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc\u03c2 \u03c0\u03c1\u03bf\u03c3\u03b1\u03bd\u03b1\u03c4\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u03a3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03cd\u03c0\u03b1\u03c1\u03be\u03b7 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03cd \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf\u03c5 \u03c5\u03c0\u03cc\u03b2\u03b1\u03b8\u03c1\u03bf\u03c5<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>Myositis \/ antisynthetase panel<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u0391\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03c9\u03bd \u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u0392\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c4\u03bf Jo-1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03ae \u03bf\u03c1\u03b9\u03b1\u03ba\u03cc<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>CRP \/ \u03a4\u039a\u0395<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u0394\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u03a3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1, \u03cc\u03c7\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>HRCT \u03b8\u03ce\u03c1\u03b1\u03ba\u03bf\u03c2<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u0388\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7\u03c2 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u039a\u03b1\u03b8\u03bf\u03c1\u03af\u03b6\u03b5\u03b9 \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03c0\u03cc\u03c3\u03bf \u03b5\u03ba\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>\u03a3\u03c0\u03b9\u03c1\u03bf\u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \/ DLCO<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u039b\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03cc\u03bd\u03c9\u03bd<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u03a7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03c3\u03c4\u03b7 baseline \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf follow-up<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\"><strong>\u0397\u039c\u0393, MRI \u03bc\u03c5\u03ce\u03bd \u03ae \u03b2\u03b9\u03bf\u03c8\u03af\u03b1<\/strong><\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u038c\u03c4\u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c4\u03b5\u03ba\u03bc\u03b7\u03c1\u03af\u03c9\u03c3\u03b7 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1\u03c2<\/td>\n<td style=\"border: 1px solid #e5e7eb; padding: 10px;\">\u03a3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03cc\u03c4\u03b1\u03bd \u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c4\u03b7<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p style=\"margin-top: 14px;\">\u039f \u03c0\u03b9\u03bf \u03c3\u03c9\u03c3\u03c4\u03cc\u03c2 \u03c4\u03c1\u03cc\u03c0\u03bf\u03c2 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03b2\u03b1\u03c3\u03c4\u03b5\u03af \u03c4\u03bf anti-Jo-1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bd\u03b1 \u03c4\u03bf \u03b4\u03b5\u03b9 \u03ba\u03b1\u03bd\u03b5\u03af\u03c2 \u03c9\u03c2<br \/>\n<strong>\u03bc\u03ad\u03c1\u03bf\u03c2 \u03b5\u03bd\u03cc\u03c2 \u03c7\u03ac\u03c1\u03c4\u03b7<\/strong>, \u03cc\u03c7\u03b9 \u03c9\u03c2 \u03bc\u03bf\u03bd\u03b1\u03b4\u03b9\u03ba\u03cc \u03b4\u03b5\u03af\u03ba\u03c4\u03b7. \u039f \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03c4\u03cc\u03c2<br \/>\n\u03c0\u03bf\u03c5 \u03b4\u03af\u03bd\u03b5\u03b9 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ac \u03b1\u03be\u03b9\u03cc\u03c0\u03b9\u03c3\u03c4\u03b7 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 12 ==================== --><\/p>\n<section id=\"section12\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">12<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0397 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5 anti-Jo-1 \u03b3\u03b9\u03b1 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03c5\u03c2<\/span><\/h2>\n<p>\u0391\u03c5\u03c4\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03af\u03c3\u03c9\u03c2 \u03b7 \u03c0\u03b9\u03bf \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b7 \u03b5\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03ac\u03c1\u03b8\u03c1\u03bf\u03c5. \u03a4\u03bf anti-Jo-1 \u03ad\u03c7\u03b5\u03b9 \u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1 \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5<br \/>\n<strong>\u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1<\/strong> \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03bc\u03b5 <strong>\u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1<\/strong>. \u03a3\u03b5 \u03b1\u03c1\u03ba\u03b5\u03c4\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2, \u03bc\u03ac\u03bb\u03b9\u03c3\u03c4\u03b1, \u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae<br \/>\n\u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03b5\u03af \u03bd\u03c9\u03c1\u03af\u03c2, \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03ae \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b7\u03b3\u03b7\u03b8\u03b5\u03af \u03c4\u03b7\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ad\u03bd\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<br \/>\n\u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03bc\u03cc\u03bd\u03bf \u03c3\u03b5 \u00ab\u03bc\u03c5\u03ca\u03ba\u03cc\u00bb \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf, \u03b1\u03bb\u03bb\u03ac \u03c3\u03b5 \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03c0\u03bd\u03b5\u03c5\u03bc\u03cc\u03bd\u03c9\u03bd.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7, \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03b5 anti-Jo-1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03bb\u03b5\u03b3\u03c7\u03b8\u03b5\u03af \u03b1\u03bd \u03ad\u03c7\u03b5\u03b9:<\/p>\n<ul style=\"padding-left: 18px; margin: 0 0 12px;\">\n<li>\u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03b1\u03bd\u03c4\u03bf\u03c7\u03ae\u03c2 \u03c3\u03c4\u03b7\u03bd \u03ba\u03cc\u03c0\u03c9\u03c3\u03b7,<\/li>\n<li>\u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03bf \u03be\u03b7\u03c1\u03cc \u03b2\u03ae\u03c7\u03b1,<\/li>\n<li>\u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1 \u03c3\u03b5 \u03c0\u03c1\u03bf\u03c3\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1,<\/li>\n<li>\u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03b7 \u03c3\u03c0\u03b9\u03c1\u03bf\u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \u03ae \u03c3\u03c4\u03b7 DLCO,<\/li>\n<li>\u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ae \u03bc\u03b5 ILD \u03c3\u03c4\u03b7\u03bd HRCT.<\/li>\n<\/ul>\n<p>\u03a0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1, \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bc\u03cd\u03b5\u03c2 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03c3\u03b5 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1, \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 CK \u03ba\u03b1\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03b2\u03ac\u03c1\u03c5\u03bd\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2.<br \/>\n\u03a5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b7 \u03bc\u03c5\u03ca\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bf\u03c0\u03bf\u03af\u03bf\u03c5\u03c2 \u03c4\u03bf \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc \u03c3\u03ba\u03ad\u03bb\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b5\u03bc\u03c6\u03b1\u03bd\u03ad\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf \u03bc\u03c5\u03ca\u03ba\u03cc.<br \/>\n\u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc\u03c2 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c3\u03c4\u03b5\u03c1\u03b5\u03cc\u03c4\u03c5\u03c0\u03b1, \u03b1\u03bb\u03bb\u03ac \u03c3\u03c4\u03bf \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03bf\u03c5 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03bf\u03cd.<\/p>\n<p>\u039c\u03b5 \u03b1\u03c0\u03bb\u03ac \u03bb\u03cc\u03b3\u03b9\u03b1, \u03ad\u03bd\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti-Jo-1 \u03b4\u03b5\u03bd \u03bb\u03ad\u03b5\u03b9 \u03bc\u03cc\u03bd\u03bf \u00ab\u03c8\u03ac\u03be\u03b5 \u03b3\u03b9\u03b1 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1\u00bb. \u039b\u03ad\u03b5\u03b9 \u03ba\u03b1\u03b9<br \/>\n<strong>\u00ab\u03bc\u03b7\u03bd \u03be\u03b5\u03c7\u03ac\u03c3\u03b5\u03b9\u03c2 \u03bd\u03b1 \u03b5\u03bb\u03ad\u03b3\u03be\u03b5\u03b9\u03c2 \u03c0\u03c1\u03bf\u03c3\u03b5\u03ba\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03c5\u03c2 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2\u00bb<\/strong>. \u0391\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03c0\u03bf\u03c5 \u03ba\u03ac\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03b7\u03bd \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7<br \/>\n\u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c9\u03c3\u03c4\u03ae \u03c0\u03b1\u03c1\u03b1\u03c0\u03bf\u03bc\u03c0\u03ae \u03c3\u03b5 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03bf \u03ae\/\u03ba\u03b1\u03b9 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03bb\u03cc\u03b3\u03bf.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 13 ==================== --><\/p>\n<section id=\"section13\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">13<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/span><\/h2>\n<p>\u0391\u03bd \u03c4\u03b5\u03b8\u03b5\u03af \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd \u03ae \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03bc\u03b5 anti-Jo-1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b4\u03b5\u03bd \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03bc\u03b5 \u03c4\u03bf \u03af\u03b4\u03b9\u03bf<br \/>\n\u03c4\u03bf \u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1. \u0397 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03ac\u03be\u03b7 \u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03b5 \u03ad\u03bd\u03b1<br \/>\n<strong>\u03c0\u03bf\u03bb\u03c5\u03c0\u03b1\u03c1\u03b1\u03b3\u03bf\u03bd\u03c4\u03b9\u03ba\u03cc follow-up<\/strong> \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9:<\/p>\n<ul style=\"padding-left: 18px; margin: 0 0 12px;\">\n<li>\u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7,<\/li>\n<li>\u03bc\u03c5\u03ca\u03ba\u03ac \u03ad\u03bd\u03b6\u03c5\u03bc\u03b1 \u03cc\u03c0\u03c9\u03c2 <strong>CK<\/strong>,<\/li>\n<li>\u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2 \u03cc\u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03bd\u03cc\u03b7\u03bc\u03b1,<\/li>\n<li><strong>\u03c3\u03c0\u03b9\u03c1\u03bf\u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7, DLCO<\/strong> \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03ae HRCT,<\/li>\n<li>\u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03b1 \u03b9\u03b1\u03c4\u03c1\u03cc.<\/li>\n<\/ul>\n<p>\u03a3\u03b5 \u03bc\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ae \u03c4\u03bf\u03c5 anti-Jo-1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03ba\u03ac\u03c0\u03bf\u03b9\u03b1 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5, \u03b1\u03bb\u03bb\u03ac \u03b1\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1<br \/>\n\u03bc\u03b5 \u03c4\u03bf\u03bd \u03af\u03b4\u03b9\u03bf \u03c4\u03c1\u03cc\u03c0\u03bf. \u0393\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03bf\u03bd\u03b1\u03b4\u03b9\u03ba\u03cc\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2. \u0388\u03bd\u03b1\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03b9\u03c3\u03b8\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9<br \/>\n\u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b1, \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 CK \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03b5\u03bd\u03ce \u03bf \u03c4\u03af\u03c4\u03bb\u03bf\u03c2 \u03bd\u03b1 \u03bc\u03b7\u03bd \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03c4\u03cc\u03c3\u03bf \u03b5\u03bd\u03c4\u03c5\u03c0\u03c9\u03c3\u03b9\u03b1\u03ba\u03ac. \u03a4\u03bf \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03bf \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af<br \/>\n\u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b5\u03af. \u0393\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03b7 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 follow-up \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae<\/strong> \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03bc\u03bf\u03bd\u03bf\u03b4\u03b9\u03ac\u03c3\u03c4\u03b1\u03c4\u03b7.<\/p>\n<p>\u0391\u03c0\u03cc \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03ac\u03c0\u03bf\u03c8\u03b7, \u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03be\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bf\u03c1\u03b3\u03b1\u03bd\u03c9\u03bc\u03ad\u03bd\u03b1, \u03bc\u03b5 \u03c3\u03c5\u03b3\u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03b1\u03c6\u03ae \u03b3\u03bd\u03ce\u03c3\u03b7 \u03c4\u03bf\u03c5<br \/>\n\u03c4\u03b9 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ce\u03c2 \u03b5\u03bb\u03ad\u03b3\u03c7\u03b5\u03c4\u03b1\u03b9 \u03ba\u03ac\u03b8\u03b5 \u03c6\u03bf\u03c1\u03ac: \u03bc\u03c5\u03c2, \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b1\u03c2, \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03ae \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c6\u03bf\u03c1\u03c4\u03af\u03bf.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 14 ==================== --><\/p>\n<section id=\"section14\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">14<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03cc\u03c4\u03b5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7<\/span><\/h2>\n<p>\u0391\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ae\u03b4\u03b7 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti-Jo-1 \u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5, \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd.<br \/>\n\u0397 \u03c0\u03b9\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03af\u03b1 \u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03bf <strong>\u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03cc<\/strong>. \u0391\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03b5\u03af \u03ae \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03c9\u03b8\u03b5\u03af \u03b4\u03cd\u03c3\u03c0\u03bd\u03bf\u03b9\u03b1, \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c0\u03c4\u03ce\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03bf\u03c7\u03ae\u03c2,<br \/>\n\u03b1\u03bd \u03bf \u03b2\u03ae\u03c7\u03b1\u03c2 \u03b5\u03c0\u03b9\u03bc\u03ad\u03bd\u03b5\u03b9 \u03c7\u03c9\u03c1\u03af\u03c2 \u03ac\u03bb\u03bb\u03b7 \u03b5\u03be\u03ae\u03b3\u03b7\u03c3\u03b7 \u03ae \u03b1\u03bd \u03b7 \u03b1\u03bd\u03b1\u03c0\u03bd\u03bf\u03ae \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03b1 \u03c0\u03b9\u03bf \u03b4\u03cd\u03c3\u03ba\u03bf\u03bb\u03b7, \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b5\u03c0\u03b1\u03bd\u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7.<br \/>\n\u0397 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03bf\u03c5\u03bd \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n<p>\u0386\u03bc\u03b5\u03c3\u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd:<\/p>\n<ul style=\"padding-left: 18px; margin: 0 0 12px;\">\n<li>\u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 <strong>\u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1\u03c2<\/strong>,<\/li>\n<li>\u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03b5 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03b9\u03bd \u03ae\u03c4\u03b1\u03bd \u03b5\u03cd\u03ba\u03bf\u03bb\u03b5\u03c2,<\/li>\n<li>\u03bd\u03ad\u03b1 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c0\u03cc \u03b1\u03c1\u03b8\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2 \u03ae Raynaud,<\/li>\n<li>\u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03ac\u03bd\u03bf\u03b4\u03bf\u03c2 CK \u03ae \u03ac\u03bb\u03bb\u03c9\u03bd \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ce\u03bd \u03b4\u03b5\u03b9\u03ba\u03c4\u03ce\u03bd \u03c3\u03b5 \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc \u03c0\u03b5\u03c1\u03b9\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03cc,<\/li>\n<li>\u03bd\u03ad\u03b1 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03b3\u03b9\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03bb\u03cc\u03b3\u03c9 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1\u03c2 \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae\u03c2.<\/li>\n<\/ul>\n<p>\u03a4\u03bf \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03bc\u03ae\u03bd\u03c5\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf anti-Jo-1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u00ab\u03c7\u03b1\u03c1\u03c4\u03af \u03c3\u03c5\u03c1\u03c4\u03b1\u03c1\u03b9\u03bf\u03cd\u00bb. \u038c\u03c4\u03b1\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae,<br \/>\n\u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03bd\u03b5\u03c1\u03b3\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03c0\u03b1\u03b8\u03b7\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03bc\u03bf\u03bd\u03ae. \u0397 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03b1\u03bd\u03c4\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03ba\u03ac\u03bd\u03b5\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03cc\u03c4\u03b1\u03bd \u03c4\u03bf \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc \u03c3\u03ba\u03ad\u03bb\u03bf\u03c2<br \/>\n\u03b1\u03c1\u03c7\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9.<\/p>\n<\/section>\n<p><!-- ==================== SECTION 15 ==================== --><\/p>\n<section id=\"section15\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">15<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b5\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/span><\/h2>\n<details style=\"margin-bottom: 14px; border: 1px solid #e5e7eb; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a4\u03b1 anti-Jo-1 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03c3\u03af\u03b3\u03bf\u03c5\u03c1\u03b1 \u03cc\u03c4\u03b9 \u03ad\u03c7\u03c9 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1;<\/summary>\n<p>\u038c\u03c7\u03b9. \u0388\u03bd\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03b9 \u03ad\u03bd\u03c4\u03bf\u03bd\u03b1 \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c8\u03af\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1, \u03c4\u03b1 \u03bc\u03c5\u03ca\u03ba\u03ac \u03ad\u03bd\u03b6\u03c5\u03bc\u03b1, \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03cc\u03c0\u03bf\u03c5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03ae\/\u03ba\u03b1\u03b9 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e5e7eb; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0391\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc, \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03bb\u03ad\u03b3\u03be\u03c9 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2;<\/summary>\n<p>\u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03bd\u03b1\u03b9, \u03b3\u03b9\u03b1\u03c4\u03af \u03c4\u03bf anti-Jo-1 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bc\u03b5 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bc\u03b5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c6\u03bf\u03c1\u03ad\u03c2 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b7\u03b3\u03b7\u03b8\u03b5\u03af \u03ae \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc \u03c4\u03b1 \u03bc\u03c5\u03ca\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e5e7eb; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0391\u03bd \u03c4\u03bf anti-Jo-1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc, \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd;<\/summary>\n<p>\u038c\u03c7\u03b9. \u03a5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd, \u03cc\u03c0\u03c9\u03c2 PL-7, PL-12, EJ \u03ba\u03b1\u03b9 OJ, \u03b3\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc \u03c3\u03b5 \u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af \u03b5\u03c5\u03c1\u03cd\u03c4\u03b5\u03c1\u03bf panel.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e5e7eb; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1;<\/summary>\n<p>\u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03cc\u03c7\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03af\u03b4\u03b9\u03bf \u03c4\u03bf anti-Jo-1, \u03b1\u03bb\u03bb\u03ac \u03b1\u03bd \u03b3\u03af\u03bd\u03bf\u03c5\u03bd \u03c4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b5 \u03c4\u03b9\u03c2 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03bf\u03c5 \u03ae \u03c4\u03bf\u03c5 \u03b3\u03b9\u03b1\u03c4\u03c1\u03bf\u03cd \u03c3\u03b1\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e5e7eb; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03bc\u03cc\u03bd\u03bf \u03bc\u03b5 \u03c4\u03bf\u03bd \u03c4\u03af\u03c4\u03bb\u03bf \u03c4\u03bf\u03c5 anti-Jo-1;<\/summary>\n<p>\u038c\u03c7\u03b9. \u0397 \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03b5\u03ba\u03c4\u03b9\u03bc\u03ac\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bc\u03b5 \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1, \u03c4\u03b7\u03bd CK, \u03ba\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03bc\u03b5 \u03c3\u03c0\u03b9\u03c1\u03bf\u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7, DLCO \u03ae HRCT.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e5e7eb; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03bd\u03b1 \u03b2\u03b3\u03b5\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c3\u03b5 panel \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b1 \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1;<\/summary>\n<p>\u039d\u03b1\u03b9. \u03a3\u03c5\u03c7\u03bd\u03ac \u03c4\u03bf anti-Jo-1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03c0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1 \u03bc\u03b5 ANA, ENA \u03ae \u03c0\u03bb\u03ae\u03c1\u03b5\u03c2 myositis panel, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03c6\u03b1\u03bd\u03b5\u03af \u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b5\u03c5\u03c1\u03cd\u03c4\u03b5\u03c1\u03bf \u03ae \u03c0\u03b9\u03bf \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb.<\/p>\n<\/details>\n<\/section>\n<p><!-- ==================== SECTION 16 ==================== --><\/p>\n<section id=\"section16\" style=\"margin: 26px 0;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">16<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/span><\/h2>\n<div style=\"background: #f8fafc; border: 1px solid #e5e7eb; border-radius: 14px; padding: 16px 18px;\">\n<p style=\"margin: 0 0 10px;\"><strong>\u2022 \u03a4\u03bf anti-Jo-1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1<\/strong> \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bc\u03b5 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b5\u03c2.<\/p>\n<p style=\"margin: 0 0 10px;\"><strong>\u2022 \u0388\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2<\/strong>, \u03b3\u03b9\u03b1\u03c4\u03af \u03b7 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03ac \u03c4\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bc\u03b5 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1.<\/p>\n<p style=\"margin: 0 0 10px;\"><strong>\u2022 \u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03b5\u03af \u03bc\u03cc\u03bd\u03b7 \u03c4\u03b7\u03c2 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/strong>. \u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, CK, \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03ba\u03b1\u03b9 \u03cc\u03c0\u03bf\u03c5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7.<\/p>\n<p style=\"margin: 0 0 10px;\"><strong>\u2022 \u0391\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc anti-Jo-1 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03b5\u03b9 \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf<\/strong>, \u03b3\u03b9\u03b1\u03c4\u03af \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 antisynthetase \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1.<\/p>\n<p style=\"margin: 0;\"><strong>\u2022 \u0397 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc<\/strong> \u03c0\u03bf\u03c5 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc, \u03c4\u03b7\u03bd \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c0\u03bb\u03ae\u03c1\u03b5\u03c2 \u03c3\u03cd\u03bd\u03bf\u03bb\u03bf \u03c4\u03c9\u03bd \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd.<\/p>\n<\/div>\n<\/section>\n<p><!-- ==================== SECTION 17 ==================== --><\/p>\n<section id=\"section17\" style=\"margin: 26px 0 10px;\">\n<h2 style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(135deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: inset 0 1px 0 rgba(255,255,255,.85),0 4px 10px rgba(0,0,0,.10); flex: 0 0 36px;\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">17<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd &amp; \u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/span><\/h2>\n<p style=\"margin: 0 0 14px;\">\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03b9\u03b1\u03c4\u03c1\u03cc \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03cc \u03bc\u03b1\u03c2. \u039c\u03c0\u03bf\u03c1\u03b5\u03af\u03c4\u03b5 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03c3\u03b5\u03c4\u03b5 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ae \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.<\/p>\n<div style=\"background: #fdf2f2; border: 1px solid #b70000; border-radius: 12px; padding: 18px 16px; margin: 0 0 22px; text-align: center;\">\n<p style=\"margin: 0 0 10px; font-size: 15px; color: #111827;\">\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 anti-Jo-1 \u03b1\u03c0\u03cc \u03b9\u03b1\u03c4\u03c1\u03cc \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03cc \u03bc\u03b1\u03c2, \u03bc\u03b5 \u03ba\u03b1\u03b8\u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1, \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae.<\/p>\n<div style=\"display: flex; flex-wrap: wrap; gap: 10px; justify-content: center; margin: 12px 0 8px;\"><a style=\"display: inline-flex; align-items: center; justify-content: center; width: 200px; height: 44px; white-space: nowrap; background: #b70000; color: #ffffff; text-decoration: none; border-radius: 8px; font-weight: bold;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/about-us\/appointments\/\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd<\/a><br \/>\n<a style=\"display: inline-flex; align-items: center; justify-content: center; width: 200px; height: 44px; white-space: nowrap; background: #b70000; color: #ffffff; text-decoration: none; border-radius: 8px; font-weight: bold;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\">\u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd<\/a><\/div>\n<p style=\"margin: 8px 0 0; font-size: 14px;\">\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">ARUP Consult. <em>Inflammatory Myopathies.<\/em><br \/>\n<a href=\"https:\/\/arupconsult.com\/content\/inflammatory-myopathies\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/arupconsult.com\/content\/inflammatory-myopathies<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">Mayo Clinic Laboratories. <em>Jo 1 Antibodies, IgG, Serum.<\/em><br \/>\n<a href=\"https:\/\/www.mayocliniclabs.com\/test-catalog\/Overview\/800219\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.mayocliniclabs.com\/test-catalog\/Overview\/800219<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">The Myositis Association. <em>Antisynthetase Syndrome.<\/em><br \/>\n<a href=\"https:\/\/www.myositis.org\/about-myositis\/types-of-myositis\/antisynthetase-syndrome\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.myositis.org\/about-myositis\/types-of-myositis\/antisynthetase-syndrome\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">Solomon J, et al. <em>Myositis-related interstitial lung disease and antisynthetase syndrome.<\/em><br \/>\n<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3676869\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3676869\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\">Yang H, et al. <em>Clinical and prognostic associations of anti-Jo-1 antibody levels in patients with antisynthetase syndrome.<\/em><br \/>\n<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11137886\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11137886\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin: 6px 0; line-height: 1.35; font-size: 14px;\"><strong>\u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u2013 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u039b\u03b1\u03bc\u03af\u03b1<\/strong><br \/>\n<a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"noopener\">https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/<\/a><\/div>\n<div style=\"background: #f1f5f9; border-left: 4px solid #2563eb; padding: 10px 14px; border-radius: 8px; margin-top: 10px;\"><strong style=\"color: #1d4ed8;\">\u0395\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03bc\u03ad\u03bb\u03b5\u03b9\u03b1:<\/strong><br \/>\n\u0394\u03c1. \u03a0\u03b1\u03bd\u03c4\u03b5\u03bb\u03ae\u03c2 \u0391\u03bd\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03cc\u03c0\u03bf\u03c5\u03bb\u03bf\u03c2, \u0399\u03b1\u03c4\u03c1\u03cc\u03c2 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u2013 \u0392\u03b9\u03bf\u03c0\u03b1\u03b8\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2<br \/>\n\u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u039b\u03b1\u03bc\u03af\u03b1\u03c2, \u0388\u03c3\u03bb\u03b9\u03bd 19, \u039b\u03b1\u03bc\u03af\u03b1 35100<br \/>\n\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n<\/section>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-Jo-1 \u2013 \u03a6\u03b9\u03bb\u03b9\u03ba\u03cc\u03c2 \u039f\u03b4\u03b7\u03b3\u03cc\u03c2 \u0394\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7: 29 \u03a3\u03b5\u03c0\u03c4\u03b5\u03bc\u03b2\u03c1\u03af\u03bf\u03c5 2025 \u2022 \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7: 4 \u0391\u03c0\u03c1\u03b9\u03bb\u03af\u03bf\u03c5 2026 \u03a3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7 \u03c0\u03b5\u03c1\u03af\u03bb\u03b7\u03c8\u03b7: \u03a4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-Jo-1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bc\u03b5 \u03c4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b1\u03c3\u03ce\u03bd, \u03c4\u03b9\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bc\u03b5 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1. \u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b4\u03b5\u03bd \u03bc\u03c0\u03b1\u03af\u03bd\u03b5\u03b9 \u03c9\u03c2 \u03c0\u03c1\u03bf\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c3\u03b5 \u03cc\u03bb\u03bf\u03c5\u03c2, \u03b1\u03bb\u03bb\u03ac \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03bc\u03c5\u03ca\u03ba\u03ae \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1, [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":6279,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2534],"tags":[2079,2078,2082,2083,2084,2081,2080],"class_list":["post-6277","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exetaseis-aimatos","tag-anti-synthetase-antibodies","tag-antisomata-anti-jo-1","tag-dermatomyositida","tag-diamesi-pnevmonopatheia","tag-exetasi-anti-jo-1","tag-polymyositida","tag-syndromo-antisynthetason"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/6277","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/comments?post=6277"}],"version-history":[{"count":3,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/6277\/revisions"}],"predecessor-version":[{"id":10762,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/6277\/revisions\/10762"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media\/6279"}],"wp:attachment":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media?parent=6277"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/categories?post=6277"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/tags?post=6277"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}