{"id":5975,"date":"2025-09-17T10:27:47","date_gmt":"2025-09-17T07:27:47","guid":{"rendered":"https:\/\/mikrobiologikolamia.gr\/staging\/?p=5975"},"modified":"2026-01-19T07:08:24","modified_gmt":"2026-01-19T05:08:24","slug":"anti-ccp","status":"publish","type":"post","link":"https:\/\/mikrobiologikolamia.gr\/staging\/anti-ccp\/","title":{"rendered":"Anti-CCP \u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1: \u03a4\u03b9 \u0394\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03b7 \u0395\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 &#038; \u03a0\u03cc\u03c4\u03b5 \u0391\u03bd\u03b7\u03c3\u03c5\u03c7\u03b5\u03af"},"content":{"rendered":"<h1>Anti-CCP \u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1: \u03a4\u03b9 \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 &amp; \u03c0\u03cc\u03c4\u03b5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b7\u03c3\u03c5\u03c7\u03b7\u03c4\u03b9\u03ba\u03ae<\/h1>\n<p style=\"font-size: 14px; color: #6b7280; margin: 6px 0 0;\">\u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7:<br \/>\n<time datetime=\"2026-01-08\">8 \u0399\u03b1\u03bd\u03bf\u03c5\u03b1\u03c1\u03af\u03bf\u03c5 2026<\/time><\/p>\n<p><!-- MINI INFOBOX --><\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0 18px;\"><strong>\u03a3\u03b5 1 \u03bb\u03b5\u03c0\u03c4\u03cc:<\/strong><br \/>\n\u03a4\u03b1 <strong>anti-CCP<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03c0\u03b9\u03bf \u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1.<br \/>\n\u039c\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1,<br \/>\n\u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03bf\u03cd\u03bd \u03bc\u03cc\u03bd\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7.<\/div>\n<nav id=\"toc\" style=\"background: #f9fafb; border: 1px solid #e5e7eb; border-radius: 14px; padding: 14px; margin: 16px 0;\" aria-label=\"\u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1\"><strong>\ud83d\udcd1 \u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1<\/strong><\/p>\n<ol style=\"margin: 10px 0 0 18px; line-height: 1.75;\">\n<li><a style=\"color: #dc2626;\" href=\"#sec1\">1. \u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-CCP<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec2\">2. \u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03ba\u03b9\u03c4\u03c1\u03bf\u03c5\u03bb\u03bb\u03b9\u03bd\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec3\">3. \u0393\u03b9\u03b1\u03c4\u03af \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec4\">4. \u03a0\u03cc\u03c4\u03b5 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b6\u03b7\u03c4\u03b7\u03b8\u03b5\u03af<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec5\">5. \u0394\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec6\">6. \u03a6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec7\">7. \u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti-CCP<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec8\">8. Anti-CCP &amp; \u03a1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u0391\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec9\">9. Anti-CCP vs \u03a1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03a0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 (RF)<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec10\">10. \u03a3\u03c5\u03bd\u03bf\u03b4\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec11\">11. \u03a0\u03cc\u03c4\u03b5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec12\">12. Anti-CCP &amp; \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec13\">13. \u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2 (FAQ)<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec14\">14. \u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec15\">15. \u03a4\u03b9 \u0394\u0395\u039d \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 anti-CCP<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec16\">16. \u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec17\">17. \u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#sec18\">18. \u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/a><\/li>\n<\/ol>\n<\/nav>\n<hr style=\"border: 0; border-top: 2px solid #d1d5db; margin: 14px 0 18px;\" \/>\n<p><!-- SECTION 1 --><\/p>\n<h2 id=\"sec1\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">1<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-CCP<\/span><\/h2>\n<p>\u03a4\u03b1 <strong>\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 anti-CCP (anti-Cyclic Citrullinated Peptide)<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac <strong>\u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong> \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1.<br \/>\n\u03a3\u03c7\u03b7\u03bc\u03b1\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c4\u03bf \u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03b9 \u03c9\u03c2 \u00ab\u03be\u03ad\u03bd\u03b1\u00bb \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c5\u03c0\u03bf\u03c3\u03c4\u03b5\u03af <em>\u03ba\u03b9\u03c4\u03c1\u03bf\u03c5\u03bb\u03bb\u03b9\u03bd\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7<\/em>,<br \/>\n\u03bc\u03b9\u03b1 \u03bc\u03b5\u03c4\u03b1-\u03bc\u03b5\u03c4\u03b1\u03c6\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7. \u03a4\u03b1 anti-CCP \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03c3\u03c4\u03b5\u03bd\u03ac \u03bc\u03b5 \u03c4\u03b7 <strong>\u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1<\/strong>,<br \/>\n\u03bc\u03b5 \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03cc\u03bc\u03b5\u03bd\u03b7 \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03c0\u03bb\u03b7\u03c3\u03b9\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf 95\u201398% \u03c3\u03b5 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2.<\/p>\n<p>\u0397 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b1\u03c1\u03b8\u03c1\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03cc\u03c4\u03b9 \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03b2\u03ac\u03c3\u03b7,<br \/>\n\u03ba\u03b1\u03b9 \u03b3\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03b1 \u03c3\u03c4\u03bf\u03bd \u03c3\u03cd\u03b3\u03c7\u03c1\u03bf\u03bd\u03bf \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0 18px; line-height: 1.65;\"><strong>\u0393\u03b9\u03b1\u03c4\u03af \u03c4\u03b1 anti-CCP \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u00ab\u03b5\u03b9\u03b4\u03b9\u03ba\u03ac\u00bb \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1;<\/strong><br \/>\n\u03a4\u03b1 anti-CCP \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03b1\u03c0\u03bb\u03bf\u03cd\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2.<br \/>\n\u03a3\u03c4\u03bf\u03c7\u03b5\u03cd\u03bf\u03c5\u03bd <strong>\u03ba\u03b9\u03c4\u03c1\u03bf\u03c5\u03bb\u03bb\u03b9\u03bd\u03c9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2<\/strong>,<br \/>\n\u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b1 \u03bc\u03b5 \u03c4\u03bf\u03bd <strong>\u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc<\/strong><br \/>\n\u03c4\u03b7\u03c2 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2.<br \/>\n\u0393\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc:<\/p>\n<ul style=\"margin: 8px 0 0 18px;\">\n<li>\u0388\u03c7\u03bf\u03c5\u03bd <strong>\u03c0\u03bf\u03bb\u03cd \u03c5\u03c8\u03b7\u03bb\u03ae \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1<\/strong> \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf<\/li>\n<li>\u039c\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd <strong>\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong><\/li>\n<li>\u03a3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 <strong>\u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1<\/strong> \u03cc\u03c4\u03b1\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03ac<\/li>\n<\/ul>\n<\/div>\n<p><!-- SECTION 2 --><\/p>\n<h2 id=\"sec2\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">2<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03ba\u03b9\u03c4\u03c1\u03bf\u03c5\u03bb\u03bb\u03b9\u03bd\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7<\/span><\/h2>\n<p>\u0397 <strong>\u03ba\u03b9\u03c4\u03c1\u03bf\u03c5\u03bb\u03bb\u03b9\u03bd\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b2\u03b9\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03ae \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03bf\u03c0\u03bf\u03af\u03b1 \u03c4\u03bf \u03ad\u03bd\u03b6\u03c5\u03bc\u03bf PAD (Peptidyl Arginine Deiminase)<br \/>\n\u03bc\u03b5\u03c4\u03b1\u03c4\u03c1\u03ad\u03c0\u03b5\u03b9 \u03b1\u03c1\u03b3\u03b9\u03bd\u03af\u03bd\u03b7 \u03c3\u03b5 \u03ba\u03b9\u03c4\u03c1\u03bf\u03c5\u03bb\u03bb\u03af\u03bd\u03b7 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03b5 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2. \u0391\u03c5\u03c4\u03ae \u03b7 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae, \u03b1\u03bb\u03bb\u03ac \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5<br \/>\n\u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03bf\u03c3\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03c9\u03bd \u03ba\u03b9\u03c4\u03c1\u03bf\u03c5\u03bb\u03bb\u03b9\u03bd\u03c9\u03bc\u03ad\u03bd\u03c9\u03bd \u03c0\u03b5\u03c0\u03c4\u03b9\u03b4\u03af\u03c9\u03bd.<\/p>\n<p>\u0397 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03ba\u03b9\u03c4\u03c1\u03bf\u03c5\u03bb\u03bb\u03b9\u03bd\u03c9\u03bc\u03ad\u03bd\u03c9\u03bd \u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03ce\u03bd \u03c3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7 \u03b9\u03c3\u03c4\u03cc (\u03c0.\u03c7. \u03b1\u03c1\u03b8\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2) \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c9\u03c2 \u00ab\u03c3\u03c0\u03af\u03b8\u03b1\u00bb \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd,<br \/>\n\u03bc\u03b5 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae anti-CCP \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03b4\u03b5\u03c3\u03bc\u03b5\u03cd\u03bf\u03c5\u03bd \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b1 \u03c4\u03bc\u03ae\u03bc\u03b1\u03c4\u03b1.<\/p>\n<p><!-- SECTION 3 --><\/p>\n<h2 id=\"sec3\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">3<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0393\u03b9\u03b1\u03c4\u03af \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/span><\/h2>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 <strong>anti-CCP<\/strong> \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd <strong>\u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2<\/strong> \u03ba\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd<br \/>\n<strong>\u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03bf\u03c1\u03b5\u03af\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5<\/strong>. \u03a3\u03b5 \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c3\u03b7 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2,<br \/>\n\u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03c5\u03c0\u03ce\u03bd\u03b5\u03b9 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03c4\u03b7\u03bd \u03c4\u03c1\u03ad\u03c7\u03bf\u03c5\u03c3\u03b1 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7, \u03b1\u03bb\u03bb\u03ac \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd <em>\u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03bf \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc<\/em> \u03c0\u03bf\u03c5 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7.<\/p>\n<p>\u0397 \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 anti-CCP \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c9\u03c3\u03c4\u03ae\u03c2 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2,<br \/>\n\u03b9\u03b4\u03af\u03c9\u03c2 \u03c3\u03c4\u03b1 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b1 \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1 \u03cc\u03c0\u03bf\u03c5 \u03bf\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bb\u03bb\u03bf\u03b9\u03ce\u03c3\u03b5\u03b9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ae \u03b1\u03c0\u03bf\u03cd\u03c3\u03b5\u03c2.<\/p>\n<p>\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b7 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c5\u03c4\u03ce\u03bd \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 <strong>\u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b2\u03c1\u03c9\u03c4\u03b9\u03ba\u03ae \u03bc\u03bf\u03c1\u03c6\u03ae<\/strong> \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5,<br \/>\n\u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03b2\u03bf\u03b7\u03b8\u03ac \u03c4\u03bf\u03bd \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03bf \u03bd\u03b1 \u03ba\u03b1\u03b8\u03bf\u03c1\u03af\u03c3\u03b5\u03b9 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b1 \u03c4\u03bf \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae.<\/p>\n<p><!-- SECTION 4 --><\/p>\n<h2 id=\"sec4\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">4<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03cc\u03c4\u03b5 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b6\u03b7\u03c4\u03b7\u03b8\u03b5\u03af<\/span><\/h2>\n<p>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 <strong>anti-CCP<\/strong> \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b6\u03b7\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 <strong>\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7\u03c2 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2<\/strong>,<br \/>\n\u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03b1\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ae\u03c0\u03b9\u03b1 \u03ae \u03b1\u03c3\u03b1\u03c6\u03ae. \u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5<br \/>\n<strong>\u03c0\u03c1\u03c9\u03b9\u03bd\u03ae \u03b4\u03c5\u03c3\u03ba\u03b1\u03bc\u03c8\u03af\u03b1 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2 \u03ac\u03bd\u03c9 \u03c4\u03c9\u03bd 30\u201360 \u03bb\u03b5\u03c0\u03c4\u03ce\u03bd<\/strong>.<\/p>\n<p>\u03a3\u03c5\u03bd\u03b9\u03c3\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03cc\u03c4\u03b1\u03bd \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 <strong>\u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03c1\u03b9\u03ba\u03cc\u03c2 \u03c0\u03cc\u03bd\u03bf\u03c2 \u03ae \u03bf\u03af\u03b4\u03b7\u03bc\u03b1 \u03bc\u03b9\u03ba\u03c1\u03ce\u03bd \u03b1\u03c1\u03b8\u03c1\u03ce\u03c3\u03b5\u03c9\u03bd<\/strong> \u03c4\u03c9\u03bd \u03c7\u03b5\u03c1\u03b9\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c1\u03c0\u03ce\u03bd,<br \/>\n\u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03bf\u03c5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 (\u03c0.\u03c7. \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2) \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bc\u03c6\u03af\u03b2\u03bf\u03bb\u03b5\u03c2 \u03ae \u03bf\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2.<\/p>\n<p>\u0397 \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b7\u03b3\u03b7\u03b8\u03b5\u03af \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c0\u03bb\u03ae\u03c1\u03bf\u03c5\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2,<br \/>\n\u03ba\u03b1\u03b8\u03ce\u03c2 \u03c4\u03b1 anti-CCP \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03bd \u03bd\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03c5\u03b8\u03bf\u03cd\u03bd <strong>\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b5\u03b3\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5<\/strong>.<br \/>\n\u0393\u03b9\u03b1 \u03c4\u03bf\u03bd \u03bb\u03cc\u03b3\u03bf \u03b1\u03c5\u03c4\u03cc, \u03b7 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03c0\u03b1\u03c1\u03b1\u03c0\u03bf\u03bc\u03c0\u03ae \u03b3\u03b9\u03b1 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03b5\u03b9 \u03c0\u03b9\u03bf \u03c3\u03c4\u03b5\u03bd\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9, \u03b5\u03c6\u03cc\u03c3\u03bf\u03bd \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af,<br \/>\n\u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7.<\/p>\n<p><!-- SECTION 5 --><br \/>\n<!-- SECTION 5 --><\/p>\n<h2 id=\"sec5\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">5<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0394\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2<\/span><\/h2>\n<p style=\"line-height: 1.65;\">\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 <strong>anti-CCP<\/strong> \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5 <strong>\u03bb\u03ae\u03c8\u03b7 \u03c6\u03bb\u03b5\u03b2\u03b9\u03ba\u03bf\u03cd \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2<\/strong><br \/>\n\u03ba\u03b1\u03b9 <strong>\u03b4\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1<\/strong>.<br \/>\n\u03a4\u03bf \u03b4\u03b5\u03af\u03b3\u03bc\u03b1 \u03c3\u03c5\u03bb\u03bb\u03ad\u03b3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03c0\u03cc \u03c6\u03bb\u03ad\u03b2\u03b1 \u03c4\u03bf\u03c5 \u03c7\u03b5\u03c1\u03b9\u03bf\u03cd \u03ba\u03b1\u03b9<br \/>\n\u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7, \u03b1\u03c3\u03c6\u03b1\u03bb\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03ce\u03b4\u03c5\u03bd\u03b7,<br \/>\n\u03cc\u03c0\u03c9\u03c2 \u03c3\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03c4\u03c5\u03c0\u03b9\u03ba\u03ae \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1.<\/p>\n<p style=\"line-height: 1.65;\">\u0394\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b5\u03c4\u03bf\u03b9\u03bc\u03b1\u03c3\u03af\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7.<br \/>\n\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03bd\u03b1 \u03b5\u03bd\u03b7\u03bc\u03b5\u03c1\u03c9\u03b8\u03b5\u03af \u03bf \u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03ae \u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03b3\u03b9\u03b1<br \/>\n<strong>\u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae<\/strong>,<br \/>\n\u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b5\u03c2 <strong>\u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2<\/strong> \u03ae<br \/>\n\u03b3\u03bd\u03c9\u03c3\u03c4\u03ac <strong>\u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1<\/strong>,<br \/>\n\u03ba\u03b1\u03b8\u03ce\u03c2 \u03c4\u03b1 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b1\u03c5\u03c4\u03ac \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c5\u03c0\u03cc\u03c8\u03b7<br \/>\n\u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0; line-height: 1.65;\">\n<p><strong>\u03a4\u03b9 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03c4\u03b5 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b1\u03b9\u03bc\u03bf\u03bb\u03b7\u03c8\u03af\u03b1:<\/strong><\/p>\n<ul style=\"margin: 8px 0 0 18px; line-height: 1.7;\">\n<li>\u0394\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae \u03c4\u03c1\u03bf\u03c6\u03ae\u03c2 \u03ae \u03c5\u03b3\u03c1\u03ce\u03bd<\/li>\n<li>\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9 \u03bf\u03c0\u03bf\u03b9\u03b1\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03ce\u03c1\u03b1 \u03c4\u03b7\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b1\u03c2<\/li>\n<li>\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2<\/li>\n<\/ul>\n<\/div>\n<p style=\"line-height: 1.65;\">\u0397 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03bc\u03b5 <strong>\u03b1\u03bd\u03bf\u03c3\u03bf\u03b5\u03bd\u03b6\u03c5\u03bc\u03b9\u03ba\u03ae \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf (ELISA)<\/strong>,<br \/>\n\u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c5\u03c8\u03b7\u03bb\u03ae \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03be\u03b9\u03bf\u03c0\u03b9\u03c3\u03c4\u03af\u03b1.<br \/>\n\u03a4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03ba\u03b1\u03bd\u03cc\u03bd\u03b1 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b1 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03b5<br \/>\n<strong>1\u20132 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2<\/strong>,<br \/>\n\u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03c6\u03cc\u03c1\u03c4\u03bf \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.<\/p>\n<p style=\"line-height: 1.65;\">\u03a4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 \u03b4\u03b5\u03bd \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b1,<br \/>\n\u03b1\u03bb\u03bb\u03ac <strong>\u03c3\u03c5\u03bd\u03b5\u03ba\u03c4\u03b9\u03bc\u03ac\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc<\/strong>,<br \/>\n\u03c4\u03b7 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03c5\u03c7\u03cc\u03bd \u03c3\u03c5\u03bd\u03bf\u03b4\u03ad\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2 \u03bc\u03b5\u03c4\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2,<br \/>\n\u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b5\u03be\u03b1\u03c7\u03b8\u03bf\u03cd\u03bd \u03b1\u03c3\u03c6\u03b1\u03bb\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03ac\u03c3\u03bc\u03b1\u03c4\u03b1.<\/p>\n<p><!-- SECTION 6 --><\/p>\n<h2 id=\"sec6\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">6<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2<\/span><\/h2>\n<p style=\"line-height: 1.65;\">\u039f\u03b9 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 <strong>anti-CCP<\/strong> \u03b5\u03ba\u03c6\u03c1\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03b5 \u03bc\u03bf\u03bd\u03ac\u03b4\u03b5\u03c2<br \/>\n<strong>U\/mL<\/strong> \u03ba\u03b1\u03b9 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c0\u03c1\u03bf\u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1<br \/>\n<strong>\u03cc\u03c1\u03b9\u03b1 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2<\/strong>.<br \/>\n\u03a4\u03b1 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ae cut-offs \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03b5\u03bb\u03b1\u03c6\u03c1\u03ce\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03c9\u03bd,<br \/>\n\u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7\u03c2,<br \/>\n\u03cc\u03bc\u03c9\u03c2 \u03b7 <strong>\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1<\/strong> \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03ba\u03bf\u03b9\u03bd\u03ae.<\/p>\n<div style=\"overflow-x: auto; margin: 12px 0;\">\n<table style=\"width: 100%; border-collapse: collapse;\">\n<thead>\n<tr style=\"background: #f9fafb;\">\n<th style=\"text-align: left; padding: 8px;\">\u03a4\u03b9\u03bc\u03ae (U\/mL)<\/th>\n<th style=\"text-align: left; padding: 8px;\">\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 8px;\">&lt; 20<\/td>\n<td style=\"padding: 8px;\">\u0391\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px;\">20\u201360<\/td>\n<td style=\"padding: 8px;\">\u03a7\u03b1\u03bc\u03b7\u03bb\u03ac \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u2013 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03b4\u03b9\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px;\">&gt; 60<\/td>\n<td style=\"padding: 8px;\">\u0399\u03c3\u03c7\u03c5\u03c1\u03ac \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u2013 \u03c5\u03c8\u03b7\u03bb\u03ae \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p style=\"line-height: 1.65;\">\u039f\u03b9 <strong>\u03c5\u03c8\u03b7\u03bb\u03bf\u03af \u03c4\u03af\u03c4\u03bb\u03bf\u03b9 anti-CCP<\/strong> \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5<br \/>\n<strong>\u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b2\u03c1\u03c9\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1<\/strong> \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5,<br \/>\n\u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ae<br \/>\n\u03b8\u03b5\u03c4\u03b9\u03ba\u03bf\u03af \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2.<br \/>\n\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03bf \u03c4\u03af\u03c4\u03bb\u03bf\u03c2 \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<br \/>\n<strong>\u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03c4\u03bf\u03c0\u03c4\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/strong><br \/>\n\u03c3\u03b5 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b7 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0; line-height: 1.65;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc:<\/strong><br \/>\n\u0397 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c4\u03c9\u03bd \u03c4\u03b9\u03bc\u03ce\u03bd <strong>anti-CCP<\/strong> \u03b4\u03b5\u03bd \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03bf\u03c4\u03ad<br \/>\n\u03c3\u03b5 \u03bc\u03af\u03b1 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7.<br \/>\n\u0391\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03bc\u03b5<br \/>\n<strong>\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1<\/strong>,<br \/>\n<strong>\u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 (RF)<\/strong>,<br \/>\n<strong>CRP\/\u03a4\u039a\u0395<\/strong> \u03ba\u03b1\u03b9<br \/>\n\u03ac\u03bb\u03bb\u03b1 \u03c3\u03c5\u03bd\u03bf\u03b4\u03ac \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1.<\/div>\n<p><!-- SECTION 7 --><\/p>\n<h2 id=\"sec7\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">7<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti-CCP<\/span><\/h2>\n<p>\u0388\u03bd\u03b1 <strong>\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc anti-CCP<\/strong> \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03b5\u03b9 <strong>\u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2<\/strong> \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7<br \/>\n\u03cc\u03c4\u03b9 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b5\u03bd\u03b5\u03c1\u03b3\u03ae \u03ae \u03b5\u03c0\u03b9\u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03b7 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03b4\u03b9\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c4\u03bf\u03c7\u03b5\u03cd\u03b5\u03b9 \u03c4\u03b9\u03c2 \u03b1\u03c1\u03b8\u03c1\u03ce\u03c3\u03b5\u03b9\u03c2.<\/p>\n<p>\u03a3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03b1\u03c1\u03b8\u03c1\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03b7 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c5\u03c4\u03ce\u03bd \u03b5\u03bd\u03b9\u03c3\u03c7\u03cd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9<br \/>\n\u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5 <strong>\u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b2\u03c1\u03c9\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1<\/strong> \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c3\u03b5 \u03b2\u03ac\u03b8\u03bf\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5.<br \/>\n\u0393\u03b9\u03b1 \u03c4\u03bf\u03bd \u03bb\u03cc\u03b3\u03bf \u03b1\u03c5\u03c4\u03cc, \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ac \u03c5\u03c0\u03cc\u03c8\u03b7 \u03c3\u03c4\u03bf\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc.<\/p>\n<p>\u0397 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd <strong>\u03c4\u03af\u03c4\u03bb\u03bf \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/strong>:<br \/>\n\u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ac \u03bc\u03b5 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03bc\u03cc\u03bd\u03b9\u03bc\u03c9\u03bd \u03b1\u03c1\u03b8\u03c1\u03b9\u03ba\u03ce\u03bd \u03b2\u03bb\u03b1\u03b2\u03ce\u03bd,<br \/>\n\u03b9\u03b4\u03af\u03c9\u03c2 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf\u03b9 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2 \u03ae \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc:<\/strong><br \/>\n\u03a5\u03c8\u03b7\u03bb\u03bf\u03af \u03c4\u03af\u03c4\u03bb\u03bf\u03b9 <strong>anti-CCP<\/strong>, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9<br \/>\n<strong>\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 (RF)<\/strong>,<br \/>\n\u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5 <strong>\u03b4\u03b9\u03b1\u03b2\u03c1\u03c9\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1<\/strong><br \/>\n\u03c4\u03b7\u03c2 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2.<\/div>\n<p><!-- SECTION 8 --><\/p>\n<h2 id=\"sec8\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">8<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">Anti-CCP &amp; \u03a1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u0391\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1<\/span><\/h2>\n<p style=\"line-height: 1.65;\">\u03a4\u03b1 <strong>anti-CCP<\/strong> \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03c5\u03b8\u03bf\u03cd\u03bd <strong>\u03c0\u03bf\u03bb\u03bb\u03ac \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b7<\/strong><br \/>\n\u03c4\u03b7\u03c2 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2, \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03c4\u03b1 \u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd<br \/>\n\u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03bc\u03cc \u03c4\u03b7\u03c2 <strong>\u03c0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03c6\u03ac\u03c3\u03b7\u03c2<\/strong> \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n<p style=\"line-height: 1.65;\">\u03a3\u03b5 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf, \u03c4\u03bf \u03ac\u03c4\u03bf\u03bc\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b7\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03b9 \u03b5\u03bc\u03c6\u03b1\u03bd\u03ae \u03b1\u03c1\u03b8\u03c1\u03b9\u03ba\u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae<br \/>\n\u03ae \u03c4\u03c5\u03c0\u03b9\u03ba\u03ac \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7,<br \/>\n\u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03c4\u03bf <strong>\u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03ae\u03b4\u03b7 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af<\/strong>.<br \/>\n\u0397 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 anti-CCP \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c9\u03c2<br \/>\n<strong>\u03c0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03cc \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c3\u03ae\u03bc\u03b1<\/strong><br \/>\n\u03cc\u03c4\u03b9 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03bc\u03b5\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2.<\/p>\n<p style=\"line-height: 1.65;\">\u039c\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03b8\u03b5\u03c4\u03b9\u03ba\u03ac anti-CCP,<br \/>\n\u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03c5\u03c8\u03b7\u03bb\u03bf\u03cd\u03c2 \u03c4\u03af\u03c4\u03bb\u03bf\u03c5\u03c2,<br \/>\n\u03ad\u03c7\u03bf\u03c5\u03bd <strong>\u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2<\/strong><br \/>\n\u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03ad\u03ba\u03b4\u03b7\u03bb\u03b7 \u03bd\u03cc\u03c3\u03bf \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03bf\u03c1\u03bf\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03ac\u03c4\u03bf\u03bc\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0; line-height: 1.65;\">\n<p><strong>\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ac \u03b7 \u03c0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c6\u03ac\u03c3\u03b7;<\/strong><\/p>\n<ul style=\"margin: 8px 0 0 18px; line-height: 1.7;\">\n<li>\u0394\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 <strong>\u03b5\u03b3\u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1<\/strong><\/li>\n<li>\u03a5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03cc\u03bc\u03c9\u03c2 <strong>\u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1<\/strong> \u03c3\u03b5 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7<\/li>\n<li>\u039f \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2<\/strong><\/li>\n<\/ul>\n<\/div>\n<p style=\"line-height: 1.65;\">\u0397 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03c6\u03ac\u03c3\u03b7\u03c2 \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03b5\u03b9<br \/>\n<strong>\u03c3\u03c4\u03b5\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<\/strong><br \/>\n\u03ba\u03b1\u03b9, \u03c3\u03b5 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2,<br \/>\n<strong>\u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7<\/strong>,<br \/>\n\u03bc\u03b5 \u03c3\u03c4\u03cc\u03c7\u03bf \u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1\u03c2,<br \/>\n\u03c4\u03b7\u03c2 \u03c4\u03b1\u03c7\u03cd\u03c4\u03b7\u03c4\u03b1\u03c2 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03bc\u03cc\u03bd\u03b9\u03bc\u03c9\u03bd \u03b1\u03c1\u03b8\u03c1\u03b9\u03ba\u03ce\u03bd \u03b2\u03bb\u03b1\u03b2\u03ce\u03bd<br \/>\n\u03cc\u03c4\u03b1\u03bd \u03b5\u03ba\u03b4\u03b7\u03bb\u03c9\u03b8\u03b5\u03af \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2.<\/p>\n<p><!-- SECTION 9 --><\/p>\n<h2 id=\"sec9\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">9<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">Anti-CCP vs RF<\/span><\/h2>\n<p>\u03a4\u03b1 <strong>anti-CCP<\/strong> \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 <strong>\u03c0\u03b9\u03bf \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac<\/strong> \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1 \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf\u03bd<br \/>\n<strong>\u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 (RF)<\/strong>, \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03c4\u03b1 \u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b1 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7.<br \/>\n\u0395\u03bd\u03ce \u03bf RF \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03c4\u03b1 anti-CCP \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03c0\u03b9\u03bf \u03c3\u03c4\u03b5\u03bd\u03ac<br \/>\n\u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03c0\u03b1\u03b8\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n<p>\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03c4\u03b1 anti-CCP \u03b4\u03b9\u03b1\u03b8\u03ad\u03c4\u03bf\u03c5\u03bd <strong>\u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03bf\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1<\/strong>, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03b7 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03ac \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1<br \/>\n\u03bc\u03b5 \u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b2\u03c1\u03c9\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1.<br \/>\n\u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03bf RF \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c3\u03b5 \u03c5\u03b3\u03b9\u03ae \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03ae \u03c3\u03b5 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b5\u03c2 \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2,<br \/>\n\u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03ac \u03c4\u03bf\u03c5.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03ac\u03be\u03b7, \u03b7 <strong>\u03b4\u03b9\u03c0\u03bb\u03ae \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 (anti-CCP + RF)<\/strong> \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1<br \/>\n\u03ba\u03b1\u03b9 \u03b2\u03bf\u03b7\u03b8\u03ac \u03c4\u03bf\u03bd \u03b9\u03b1\u03c4\u03c1\u03cc \u03bd\u03b1 \u03b5\u03ba\u03c4\u03b9\u03bc\u03ae\u03c3\u03b5\u03b9 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b1 \u03c4\u03cc\u03c3\u03bf \u03c4\u03b7 \u03b2\u03b5\u03b2\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bc\u03b5\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0; line-height: 1.65;\">\n<p><strong>Anti-CCP vs \u03a1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03a0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 (RF): \u03c4\u03b9 \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ac\u03be\u03b7<\/strong><\/p>\n<ul style=\"margin: 8px 0 0 18px;\">\n<li><strong>Anti-CCP:<\/strong> \u03a0\u03bf\u03bb\u03cd \u03c5\u03c8\u03b7\u03bb\u03ae \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b3\u03b9\u03b1 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1 \u03ba\u03b1\u03b9<br \/>\n\u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03c5\u03b8\u03b5\u03af <strong>\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1<\/strong>.<\/li>\n<li><strong>RF:<\/strong> \u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc\u03c2\u00b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c3\u03b5<br \/>\n<strong>\u03ac\u03bb\u03bb\u03b5\u03c2 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2<\/strong> \u03ae \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03c5\u03b3\u03b9\u03ae \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2.<\/li>\n<li><strong>\u0394\u03b9\u03c0\u03bb\u03ae \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 (anti-CCP + RF):<\/strong><br \/>\n\u0391\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 <strong>\u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b2\u03b5\u03b2\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1<\/strong><br \/>\n\u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5 <strong>\u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1<\/strong> \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/li>\n<\/ul>\n<\/div>\n<p><!-- SECTION 10 --><\/p>\n<h2 id=\"sec10\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">10<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03c5\u03bd\u03bf\u03b4\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2<\/span><\/h2>\n<p style=\"line-height: 1.65;\">\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 <strong>anti-CCP<\/strong> \u03b4\u03b5\u03bd \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b5\u03bd\u03c4\u03ac\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ad\u03bd\u03b1<br \/>\n<strong>\u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf<\/strong> \u03c0\u03bf\u03c5 \u03c3\u03c4\u03bf\u03c7\u03b5\u03cd\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c3\u03c6\u03b1\u03bb\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7,<br \/>\n\u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae\u03c2 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<br \/>\n\u039f \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ce\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1.<\/p>\n<p style=\"line-height: 1.65;\">\u03a3\u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03ac\u03be\u03b7, \u03c3\u03c5\u03bd\u03b5\u03ba\u03c4\u03b9\u03bc\u03ce\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1:<\/p>\n<ul style=\"margin: 10px 0 0 18px; line-height: 1.7;\">\n<li><strong>\u03a1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03a0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 (RF):<\/strong><br \/>\n\u03a3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03ce\u03bd\u03b5\u03b9 \u03c4\u03bf anti-CCP\u00b7 \u03b7 <strong>\u03b4\u03b9\u03c0\u03bb\u03ae \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1<\/strong> \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03b2\u03b5\u03b2\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2.<\/li>\n<li><strong><a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/crp-c-antidrosa-proteini-ti-einai-kai-pos-syndeetai-me-ti-flegmoni-sto-soma-sas\/\">CRP<\/a> &amp; <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/taxytita-kathizisis-erythron-tke\/\">\u03a4\u039a\u0395<\/a>:<\/strong><br \/>\n\u0394\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03cd \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2, \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf\u03b9 \u03b3\u03b9\u03b1 \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 <strong>\u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5<\/strong>.<\/li>\n<li><strong>\u0393\u03b5\u03bd\u03b9\u03ba\u03ae \u0391\u03af\u03bc\u03b1\u03c4\u03bf\u03c2:<\/strong><br \/>\n\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b4\u03b5\u03af\u03be\u03b5\u03b9 <strong>\u03b1\u03bd\u03b1\u03b9\u03bc\u03af\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5<\/strong> \u03ae \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2.<\/li>\n<li><strong>ANA (\u03b1\u03bd\u03c4\u03b9\u03c0\u03c5\u03c1\u03b7\u03bd\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1):<\/strong><br \/>\n\u03a7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b1 \u03c3\u03c4\u03b7 <strong>\u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/strong> \u03b1\u03c0\u03cc \u03ac\u03bb\u03bb\u03b1 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1.<\/li>\n<li><strong>Anti-dsDNA, ENA panel:<\/strong><br \/>\n\u0396\u03b7\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c5\u03c0\u03bf\u03c8\u03af\u03b1 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03cd \u03b5\u03c1\u03c5\u03b8\u03b7\u03bc\u03b1\u03c4\u03ce\u03b4\u03bf\u03c5\u03c2 \u03bb\u03cd\u03ba\u03bf\u03c5 \u03ae \u03c3\u03c5\u03bd\u03b4\u03b5\u03c4\u03b9\u03ba\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1\u03c2.<\/li>\n<li><strong>\u0392\u03b9\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 (\u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ac, \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ac):<\/strong><br \/>\n\u0391\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf\u03c2 \u03c4\u03cc\u03c3\u03bf \u03b3\u03b9\u03b1 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae.<\/li>\n<\/ul>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0; line-height: 1.65;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b5\u03af\u03c9\u03c3\u03b7:<\/strong><br \/>\n\u039f \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bd\u03bf\u03b4\u03ce\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b7 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2,<br \/>\n\u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03bf <strong>\u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03bc\u03cc\u03c2 \u03ac\u03bb\u03bb\u03c9\u03bd \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03c9\u03bd \u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03c9\u03b4\u03ce\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd<\/strong>,<br \/>\n\u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03c3\u03c9\u03c3\u03c4\u03ae \u03ba\u03b1\u03b8\u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2.<\/div>\n<p><!-- SECTION 11 --><\/p>\n<h2 id=\"sec11\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">11<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03cc\u03c4\u03b5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2<\/span><\/h2>\n<p style=\"line-height: 1.65;\"><strong>\u03a0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2<\/strong> \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 anti-CCP<br \/>\n\u03b4\u03b5\u03bd \u03c3\u03c5\u03bc\u03b2\u03b1\u03b4\u03af\u03b6\u03b5\u03b9 \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03ae \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd<br \/>\n<strong>\u03cd\u03c0\u03bf\u03c0\u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd<\/strong>, \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03b1\u03bd \u03c4\u03bf \u03b1\u03c1\u03c7\u03b9\u03ba\u03cc \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1<br \/>\n\u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03ae \u03bf\u03c1\u03b9\u03b1\u03ba\u03cc.<\/p>\n<p style=\"line-height: 1.65;\">\u0397 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03b3\u03b9\u03b1 \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c3\u03c4\u03b9\u03c2 \u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2:<\/p>\n<ul style=\"margin: 10px 0 0 18px; line-height: 1.7;\">\n<li><strong>\u039f\u03c1\u03b9\u03b1\u03ba\u03ac \u03ae \u03c7\u03b1\u03bc\u03b7\u03bb\u03ac \u03b8\u03b5\u03c4\u03b9\u03ba\u03ac anti-CCP<\/strong>,<br \/>\n\u03b9\u03b4\u03af\u03c9\u03c2 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b1\u03c1\u03b8\u03c1\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1.<\/li>\n<li><strong>\u0391\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc anti-CCP \u03bc\u03b5 \u03cd\u03c0\u03bf\u03c0\u03c4\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1<\/strong>,<br \/>\n\u03cc\u03c0\u03c9\u03c2 \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b7 \u03c0\u03c1\u03c9\u03b9\u03bd\u03ae \u03b4\u03c5\u03c3\u03ba\u03b1\u03bc\u03c8\u03af\u03b1 \u03ae \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03c1\u03b9\u03ba\u03cc\u03c2 \u03c0\u03cc\u03bd\u03bf\u03c2 \u03bc\u03b9\u03ba\u03c1\u03ce\u03bd \u03b1\u03c1\u03b8\u03c1\u03ce\u03c3\u03b5\u03c9\u03bd.<\/li>\n<li><strong>\u0391\u03c3\u03c5\u03bc\u03c6\u03c9\u03bd\u03af\u03b1 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd<\/strong><br \/>\n(\u03c0.\u03c7. \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc anti-CCP \u03b1\u03bb\u03bb\u03ac \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ae \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/crp-c-antidrosa-proteini-ti-einai-kai-pos-syndeetai-me-ti-flegmoni-sto-soma-sas\/\">CRP<\/a>).<\/li>\n<li><strong>\u0395\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03ac\u03c1\u03bf\u03b4\u03bf \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5<\/strong>,<br \/>\n\u03c0\u03b1\u03c1\u03ac \u03b1\u03c1\u03c7\u03b9\u03ba\u03ac \u03ba\u03b1\u03b8\u03b7\u03c3\u03c5\u03c7\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ac \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1.<\/li>\n<\/ul>\n<p style=\"margin-top: 12px; line-height: 1.65;\">\u03a3\u03b5 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2, \u03bf \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9<br \/>\n<strong>\u03b5\u03c0\u03b1\u03bd\u03ac\u03bb\u03b7\u03c8\u03b7 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd<\/strong>, \u03c3\u03c4\u03b5\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<br \/>\n\u03ba\u03b1\u03b9, \u03b5\u03c6\u03cc\u03c3\u03bf\u03bd \u03ba\u03c1\u03b9\u03b8\u03b5\u03af \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf, \u03c0\u03b1\u03c1\u03b1\u03c0\u03bf\u03bc\u03c0\u03ae \u03b3\u03b9\u03b1 \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0; line-height: 1.65;\">\n<p><strong>\u03a4\u03b9 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf;<\/strong><\/p>\n<ul style=\"margin: 8px 0 0 18px; line-height: 1.7;\">\n<li>\u0397 <strong>\u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/strong> \u03c3\u03c4\u03bf\u03bd \u03c7\u03c1\u03cc\u03bd\u03bf<\/li>\n<li>\u0397 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03ae \u03cc\u03c7\u03b9 <strong>\u03b1\u03bd\u03c4\u03b9\u03ba\u03b5\u03b9\u03bc\u03b5\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c1\u03b8\u03c1\u03b9\u03ba\u03ae\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2<\/strong><\/li>\n<li>\u0397 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ae <strong>\u03b4\u03b5\u03b9\u03ba\u03c4\u03ce\u03bd \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2<\/strong> (CRP, \u03a4\u039a\u0395)<\/li>\n<li>\u0397 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 <strong>\u03bd\u03ad\u03c9\u03bd \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ce\u03bd \u03b5\u03c5\u03c1\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd<\/strong><\/li>\n<\/ul>\n<\/div>\n<p style=\"line-height: 1.65;\">\u039f \u03c3\u03c4\u03cc\u03c7\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u00ab\u03c5\u03c0\u03b5\u03c1\u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u00bb,<br \/>\n\u03b1\u03bb\u03bb\u03ac \u03b7 <strong>\u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b2\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03c1\u03ce\u03b9\u03bc\u03bf \u03ae \u03b5\u03be\u03b5\u03bb\u03b9\u03c3\u03c3\u03cc\u03bc\u03b5\u03bd\u03bf \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf<\/strong><br \/>\n\u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03c6\u03b5\u03c5\u03c7\u03b8\u03b5\u03af \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<br \/>\n\u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c9\u03c3\u03c4\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7.<\/p>\n<h2 id=\"sec12\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">12<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">Anti-CCP &amp; \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7<\/span><\/h2>\n<p>\u039a\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd <strong>\u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7<\/strong>, \u03b7 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03b5\u03c4\u03b1\u03b2\u03ac\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9,<br \/>\n\u03bc\u03b5 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2<br \/>\n\u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd <strong>\u03bc\u03b5\u03c1\u03b9\u03ba\u03ae \u03ae \u03c0\u03bb\u03ae\u03c1\u03b7 \u03cd\u03c6\u03b5\u03c3\u03b7<\/strong>.<br \/>\n\u0397 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 anti-CCP, \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03c5\u03c0\u03bf\u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03b7\u03c2 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7\u03c2 \u03b4\u03b9\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1\u03c2.<\/p>\n<p>\u039c\u03b5\u03c4\u03ac \u03c4\u03bf\u03bd <strong>\u03c4\u03bf\u03ba\u03b5\u03c4\u03cc<\/strong>, \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 <strong>\u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae<\/strong> \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd,<br \/>\n\u03ba\u03b1\u03b8\u03ce\u03c2 \u03c4\u03bf \u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1 \u03b5\u03c0\u03b1\u03bd\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c0\u03c1\u03bf\u03ba\u03cd\u03b7 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7.<br \/>\n\u0393\u03b9\u03b1 \u03c4\u03bf\u03bd \u03bb\u03cc\u03b3\u03bf \u03b1\u03c5\u03c4\u03cc, \u03c3\u03c5\u03bd\u03b9\u03c3\u03c4\u03ac\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<br \/>\n\u03c3\u03c4\u03bf \u03bc\u03b5\u03c4\u03b1\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03b4\u03b9\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1.<\/p>\n<p>\u0397 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b7 \u03bb\u03ae\u03c8\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03b1\u03c0\u03bf\u03c6\u03ac\u03c3\u03b5\u03c9\u03bd<br \/>\n\u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03ba\u03cd\u03b7\u03c3\u03b7 \u03ae \u03c4\u03b7 \u03bb\u03bf\u03c7\u03b5\u03af\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1,<br \/>\n\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c5\u03c0\u03cc\u03c8\u03b7 \u03c4\u03cc\u03c3\u03bf \u03c4\u03b7 \u03bc\u03b7\u03c4\u03ad\u03c1\u03b1 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5 \u03ae \u03c4\u03bf\u03c5 \u03bd\u03b5\u03bf\u03b3\u03bd\u03bf\u03cd.<\/p>\n<p><!-- SECTION 13 FAQ --><\/p>\n<h2 id=\"sec13\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">13<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/span><\/h2>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0398\u03b5\u03c4\u03b9\u03ba\u03cc anti-CCP \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03c3\u03af\u03b3\u03bf\u03c5\u03c1\u03b1 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1;<\/summary>\n<p>\u038c\u03c7\u03b9. \u03a4\u03bf anti-CCP \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2, \u03b1\u03bb\u03bb\u03ac \u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf<br \/>\n\u03bc\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ce\u03bd \u03b5\u03c5\u03c1\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03c4\u03bf anti-CCP \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1;<\/summary>\n<p>\u039d\u03b1\u03b9. \u03a3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2,<br \/>\n\u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 anti-CCP;<\/summary>\n<p>\u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03cc\u03c7\u03b9. \u0397 \u03b5\u03c0\u03b1\u03bd\u03ac\u03bb\u03b7\u03c8\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03bd\u03cc\u03b7\u03bc\u03b1 \u03bc\u03cc\u03bd\u03bf \u03c3\u03b5 \u03bf\u03c1\u03b9\u03b1\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1<br \/>\n\u03ae \u03cc\u03c4\u03b1\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03ac\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03ad\u03bd\u03b1 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc anti-CCP \u03bd\u03b1 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf;<\/summary>\n<p>\u038c\u03c7\u03b9 \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2. \u03a5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1<br \/>\n\u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd anti-CCP \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03bf\u03af.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0395\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 anti-CCP \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2;<\/summary>\n<p>\u039d\u03b1\u03b9, \u03ad\u03bc\u03bc\u03b5\u03c3\u03b1. \u0397 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf<br \/>\n\u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03bf\u03c1\u03b5\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03c3\u03c4\u03b5\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b4\u03b9\u03c0\u03bb\u03ae \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 (anti-CCP \u03ba\u03b1\u03b9 RF);<\/summary>\n<p>\u0397 \u03c4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b7 \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 anti-CCP \u03ba\u03b1\u03b9 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1<br \/>\n\u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b2\u03b5\u03b2\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b3\u03b9\u03b1 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1<br \/>\n\u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5 \u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n<\/details>\n<h2 id=\"sec14\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">14<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae<\/span><\/h2>\n<p style=\"margin-top: 10px; line-height: 1.65;\">\u03a4\u03b1 <strong>anti-CCP<\/strong> \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03b5\u03be\u03b1\u03b9\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03b4\u03b5\u03af\u03ba\u03c4\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1,<br \/>\n\u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03b7 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af <strong>\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c3\u03ba\u03ad\u03c8\u03b7<\/strong> \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b1\u03c1\u03b9\u03b8\u03bc\u03ce\u03bd.<br \/>\n\u039f\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bb\u03ac\u03b8\u03b7 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03bf\u03c5\u03bd \u03b5\u03af\u03c4\u03b5 \u03c3\u03b5 \u03b1\u03b4\u03b9\u03ba\u03b1\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c4\u03b7 \u03b1\u03bd\u03b7\u03c3\u03c5\u03c7\u03af\u03b1<br \/>\n\u03b5\u03af\u03c4\u03b5 \u03c3\u03b5 \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2.<\/p>\n<ul style=\"margin: 12px 0 0 18px; line-height: 1.7;\">\n<li><strong>\u0398\u03b5\u03c4\u03b9\u03ba\u03cc anti-CCP \u2260 \u03b1\u03c5\u03c4\u03cc\u03bc\u03b1\u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7.<\/strong><br \/>\n\u0397 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03bc\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2,<br \/>\n\u03c6\u03c5\u03c3\u03b9\u03ba\u03ae\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03bf\u03b4\u03ce\u03bd \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ce\u03bd \u03b5\u03c5\u03c1\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd.<\/li>\n<li><strong>\u0391\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc anti-CCP \u2260 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03bc\u03cc\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/strong><br \/>\n\u03a5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03bf\u03c1\u03bf\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1,<br \/>\n\u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03b1 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b1 \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1.<\/li>\n<li><strong>\u039f \u03c4\u03af\u03c4\u03bb\u03bf\u03c2 \u03c4\u03c9\u03bd anti-CCP \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b1\u03bd\u03b1\u03ba\u03bb\u03ac \u03c4\u03b7 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.<\/strong><br \/>\n\u03a5\u03c8\u03b7\u03bb\u03ad\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7, \u03cc\u03c7\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ad\u03bd\u03c4\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c0\u03cc\u03bd\u03bf\u03c5<br \/>\n\u03ae \u03c4\u03b7 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c3\u03b5 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b7 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae.<\/li>\n<li><strong>\u03a4\u03b1 anti-CCP \u03b4\u03b5\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2.<\/strong><br \/>\n\u03a3\u03b5 \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c3\u03b7 \u03bc\u03b5 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/crp-c-antidrosa-proteini-ti-einai-kai-pos-syndeetai-me-ti-flegmoni-sto-soma-sas\/\">CRP<\/a> \u03ae <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/taxytita-kathizisis-erythron-tke\/\">\u03a4\u039a\u0395<\/a>, \u03b4\u03b5\u03bd \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03be\u03b9\u03cc\u03c0\u03b9\u03c3\u03c4\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03b3\u03c9\u03b3\u03ae.<\/li>\n<\/ul>\n<p style=\"margin: 10px 0 0 0;\">\u0397 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03bc\u03b5<br \/>\n<strong>\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1<\/strong> \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03bf\u03b4\u03ac<br \/>\n<strong>\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ac \u03ae \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1<\/strong>.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c3\u03c5\u03bc\u03c0\u03ad\u03c1\u03b1\u03c3\u03bc\u03b1:<\/strong><br \/>\n\u03a4\u03b1 <strong>anti-CCP<\/strong> \u03b1\u03c0\u03b1\u03bd\u03c4\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf \u00ab<em>\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03b4\u03b9\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1<\/em>\u00bb,<br \/>\n\u03cc\u03c7\u03b9 \u03c3\u03c4\u03bf \u00ab<em>\u03c0\u03cc\u03c3\u03bf \u03c0\u03bf\u03bd\u03ac\u03b5\u03b9 \u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2<\/em>\u00bb \u03ae \u00ab<em>\u03c0\u03ce\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2<\/em>\u00bb.<\/div>\n<h2 id=\"sec15\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">15<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u0394\u0395\u039d \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 anti-CCP<br \/>\n<\/span><\/h2>\n<ul style=\"margin-top: 10px; line-height: 1.7;\">\n<li>\u0394\u03b5\u03bd \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 <strong>\u03c4\u03b7 \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/strong><br \/>\n\u03bf\u03cd\u03c4\u03b5 \u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2.<\/li>\n<li>\u0394\u03b5\u03bd \u03ba\u03b1\u03b8\u03bf\u03c1\u03af\u03b6\u03b5\u03b9 \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 <strong>\u03c0\u03cc\u03c4\u03b5<\/strong> \u03b8\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03b5\u03af<br \/>\n\u03ae \u03b1\u03bd \u03b8\u03b1 \u03b5\u03be\u03b5\u03bb\u03b9\u03c7\u03b8\u03b5\u03af \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2.<\/li>\n<li>\u0394\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03b7\u03bd <strong>\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7<\/strong><br \/>\n\u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7.<\/li>\n<li>\u0394\u03b5\u03bd \u03b1\u03c1\u03ba\u03b5\u03af \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03c5 \u03b3\u03b9\u03b1 <strong>\u03ad\u03bd\u03b1\u03c1\u03be\u03b7 \u03ae \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2<\/strong><br \/>\n\u03c7\u03c9\u03c1\u03af\u03c2 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc\u03c6\u03b1\u03c3\u03b7.<\/li>\n<\/ul>\n<h2 id=\"sec16\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">16<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03bd\u03b1 \u03b8\u03c5\u03bc\u03ac\u03c3\u03c4\u03b5<\/span><\/h2>\n<ul style=\"margin-top: 10px; line-height: 1.7;\">\n<li>\u03a4\u03b1 <strong>anti-CCP<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03c0\u03b9\u03bf <strong>\u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2<\/strong><br \/>\n\u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7.<\/li>\n<li>\u039c\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03c5\u03b8\u03bf\u03cd\u03bd <strong>\u03c0\u03bf\u03bb\u03cd \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd<\/strong>,<br \/>\n\u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03bc\u03b5\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/li>\n<li>\u0397 <strong>\u03b4\u03b9\u03c0\u03bb\u03ae \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1<\/strong> \u03bc\u03b5 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1<br \/>\n\u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1.<\/li>\n<li>\u0397 \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9<br \/>\n\u03c3\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03bc\u03b5 <strong>\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1<\/strong> \u03ba\u03b1\u03b9 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2.<\/li>\n<li>\u0397 \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03b1\u03c0\u03cc \u03b9\u03b1\u03c4\u03c1\u03cc \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03b5\u03b9<br \/>\n<strong>\u03c3\u03c9\u03c3\u03c4\u03cc \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2<\/strong> \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2.<\/li>\n<\/ul>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 18px 0; line-height: 1.65;\"><strong>\u03a0\u03cc\u03c4\u03b5 \u03c4\u03bf anti-CCP \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc\u03c6\u03b1\u03c3\u03b7;<\/strong><br \/>\n\u0397 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03b1\u03c0\u03bf\u03ba\u03c4\u03ac <strong>\u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b2\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1<\/strong> \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd:<\/p>\n<ul style=\"margin: 8px 0 0 18px;\">\n<li><strong>\u03a3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2<\/strong><br \/>\n(\u03c0\u03c1\u03c9\u03b9\u03bd\u03ae \u03b4\u03c5\u03c3\u03ba\u03b1\u03bc\u03c8\u03af\u03b1, \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03c1\u03b9\u03ba\u03cc\u03c2 \u03c0\u03cc\u03bd\u03bf\u03c2 \u03bc\u03b9\u03ba\u03c1\u03ce\u03bd \u03b1\u03c1\u03b8\u03c1\u03ce\u03c3\u03b5\u03c9\u03bd)<\/li>\n<li><strong>\u0398\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 (RF)<\/strong><br \/>\n\u03ae \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf\u03b9 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2 (CRP\/\u03a4\u039a\u0395)<\/li>\n<li><strong>\u03a5\u03c8\u03b7\u03bb\u03cc\u03c2 \u03c4\u03af\u03c4\u03bb\u03bf\u03c2 anti-CCP<\/strong><br \/>\n(\u03cc\u03c7\u03b9 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1)<\/li>\n<\/ul>\n<p style=\"margin: 8px 0 0 0;\">\u03a3\u03b5 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf, \u03c4\u03bf anti-CCP \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c9\u03c2 <strong>\u03c0\u03c1\u03bf\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2<\/strong><br \/>\n\u03ba\u03b1\u03b9 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 <strong>\u03c3\u03c4\u03b5\u03bd\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<\/strong><br \/>\n\u03ae \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae.<\/p>\n<\/div>\n<h2 id=\"sec17\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">17<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd<\/span><\/h2>\n<p>\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd anti-CCP \u03b1\u03c0\u03cc \u03b9\u03b1\u03c4\u03c1\u03cc \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03cc \u03bc\u03b1\u03c2.<br \/>\n\u039c\u03c0\u03bf\u03c1\u03b5\u03af\u03c4\u03b5 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03c3\u03b5\u03c4\u03b5 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03ae \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.<\/p>\n<div style=\"background: #fdf2f2; border: 2px solid #b70000; border-radius: 14px; padding: 18px; text-align: center;\">\n<div><strong>\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 anti-CCP \u03ae \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf:<\/strong><\/div>\n<div style=\"display: flex; gap: 10px; justify-content: center; flex-wrap: wrap; margin-top: 10px;\"><a style=\"background: #b70000; color: #fff; padding: 12px 18px; border-radius: 12px; text-decoration: none; font-weight: 600;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"nofollow noopener\"><br \/>\n\ud83d\udcd8 \u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd<br \/>\n<\/a><br \/>\n<a style=\"background: #b70000; color: #fff; padding: 12px 18px; border-radius: 12px; text-decoration: none; font-weight: 600;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/about-us\/appointments\/\" target=\"_blank\" rel=\"nofollow noopener\"><br \/>\n\ud83d\udcc5 \u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd \u03a4\u03ce\u03c1\u03b1<br \/>\n<\/a><\/div>\n<div style=\"margin-top: 10px; color: #374151;\">\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n<\/div>\n<h2 id=\"sec18\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18),inset 0 1px 0 rgba(255,255,255,.65),inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">18<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/span><\/h2>\n<p><!-- ULTRA MINI NEJM-STYLE BIBLIOGRAPHY --><\/p>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>1. van Venrooij WJ, van Beers JJ, Pruijn GJ. <strong>Anti-CCP antibodies: a highly specific marker for rheumatoid arthritis.<\/strong> <em>Ann N Y Acad Sci<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19076400\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/19076400\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>2. Nishimura K, Sugiyama D, Kogata Y, et al. <strong>Meta-analysis of anti-CCP and rheumatoid factor.<\/strong> <em>Ann Intern Med<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17548409\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/17548409\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>3. Aletaha D, Neogi T, Silman AJ, et al. <strong>2010 ACR\/EULAR classification criteria for RA.<\/strong> <em>Arthritis Rheum<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20872595\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/20872595\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>4. Rantap\u00e4\u00e4-Dahlqvist S, et al. <strong>Anti-CCP antibodies precede rheumatoid arthritis.<\/strong> <em>Arthritis Rheum<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14558078\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/14558078\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>5. Avouac J, Gossec L, Dougados M. <strong>Diagnostic and predictive value of anti-CCP.<\/strong> <em>Ann Rheum Dis<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16644702\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/16644702\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>6. Smolen JS, et al. <strong>EULAR recommendations for RA management.<\/strong> <em>Ann Rheum Dis<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31969328\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31969328\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>7. Firestein GS, McInnes IB. <strong>Immunopathogenesis of rheumatoid arthritis.<\/strong> <em>Immunity<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27438720\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/27438720\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>8. Schellekens GA, et al. <strong>The diagnostic properties of anti-CCP.<\/strong> <em>Arthritis Rheum<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9710877\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/9710877\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>9. Aggarwal R, Liao K. <strong>Anti-citrullinated peptide antibodies in RA.<\/strong> <em>Curr Opin Rheumatol<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26882403\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/26882403\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>10. van der Helm-van Mil AHM. <strong>Prediction of RA development.<\/strong> <em>Nat Rev Rheumatol<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21270729\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/21270729\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>11. Sparks JA. <strong>Environmental risk factors for RA.<\/strong> <em>Nat Rev Rheumatol<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28653605\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28653605\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>12. Deane KD, Holers VM. <strong>The natural history of RA.<\/strong> <em>Clin Ther<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22920503\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/22920503\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>13. Majka DS, Holers VM. <strong>Can RA be prevented?<\/strong> <em>Best Pract Res Clin Rheumatol<\/em>.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18947375\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/18947375\/<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 10px; font-size: 14px;\">\n<p>14. \u0395\u03bb\u03bb\u03b7\u03bd\u03b9\u03ba\u03ae \u03a1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u0395\u03c4\u03b1\u03b9\u03c1\u03b5\u03af\u03b1. <strong>\u03a1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1 \u2013 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2.<\/strong><\/p>\n<p><a href=\"https:\/\/ere.gr\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/ere.gr<\/a><\/p>\n<\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 12px; margin-bottom: 14px; font-size: 14px;\">\n<p>15. \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u039b\u03b1\u03bc\u03af\u03b1. <strong>\u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.<\/strong><\/p>\n<p><a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"noopener\">https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/<\/a><\/p>\n<\/div>\n<p><!-- \u0395\u03a0\u0399\u03a3\u03a4\u0397\u039c\u039f\u039d\u0399\u039a\u0397 \u0395\u03a0\u0399\u039c\u0395\u039b\u0395\u0399\u0391 --><\/p>\n<div style=\"background: #f1f5f9; border-left: 4px solid #2563eb; padding: 10px 14px; border-radius: 8px; margin-top: 10px;\"><strong style=\"color: #1d4ed8;\">\u0395\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03bc\u03ad\u03bb\u03b5\u03b9\u03b1:<\/strong><br \/>\n\u0394\u03c1. \u03a0\u03b1\u03bd\u03c4\u03b5\u03bb\u03ae\u03c2 \u0391\u03bd\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03cc\u03c0\u03bf\u03c5\u03bb\u03bf\u03c2, \u0399\u03b1\u03c4\u03c1\u03cc\u03c2 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u2013 \u0392\u03b9\u03bf\u03c0\u03b1\u03b8\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2<br \/>\n\u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u039b\u03b1\u03bc\u03af\u03b1\u03c2, \u0388\u03c3\u03bb\u03b9\u03bd 19, \u039b\u03b1\u03bc\u03af\u03b1 35100<br \/>\n\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Anti-CCP \u0391\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1: \u03a4\u03b9 \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 &amp; \u03c0\u03cc\u03c4\u03b5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b7\u03c3\u03c5\u03c7\u03b7\u03c4\u03b9\u03ba\u03ae \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7: 8 \u0399\u03b1\u03bd\u03bf\u03c5\u03b1\u03c1\u03af\u03bf\u03c5 2026 \u03a3\u03b5 1 \u03bb\u03b5\u03c0\u03c4\u03cc: \u03a4\u03b1 anti-CCP \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03c0\u03b9\u03bf \u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c1\u03b5\u03c5\u03bc\u03b1\u03c4\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03c1\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1. \u039c\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b1\u03c1\u03ba\u03bf\u03cd\u03bd \u03bc\u03cc\u03bd\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7. \ud83d\udcd1 \u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1 1. \u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":5980,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2534],"tags":[819,912,2483,596,1445,820,1646],"class_list":["post-5975","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exetaseis-aimatos","tag-anti-ccp","tag-crp","tag-rf","tag-anosologikes-exetaseis","tag-avtoantisomata","tag-revmatoeidis-arthritida","tag-tke"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/5975","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/comments?post=5975"}],"version-history":[{"count":9,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/5975\/revisions"}],"predecessor-version":[{"id":8893,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/5975\/revisions\/8893"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media\/5980"}],"wp:attachment":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media?parent=5975"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/categories?post=5975"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/tags?post=5975"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}