{"id":2796,"date":"2025-05-27T21:29:07","date_gmt":"2025-05-27T18:29:07","guid":{"rendered":"https:\/\/mikrobiologikolamia.gr\/staging\/?p=2796"},"modified":"2026-01-11T16:41:03","modified_gmt":"2026-01-11T14:41:03","slug":"leqvio-inclisiran-kai-lipoproteinia","status":"publish","type":"post","link":"https:\/\/mikrobiologikolamia.gr\/staging\/leqvio-inclisiran-kai-lipoproteinia\/","title":{"rendered":"Lp(a) \u03ba\u03b1\u03b9 Inclisiran (Leqvio) \u2013 \u039a\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc\u03c2 \u039a\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2"},"content":{"rendered":"<h1>\u039b\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a) \u2013 Lp(a) \u03ba\u03b1\u03b9 Inclisiran (Leqvio): \u03a0\u03ce\u03c2 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bf \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc\u03c2 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2<\/h1>\n<p style=\"font-size: 14px; color: #6b7280; margin: 6px 0 0;\">\u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7:<br \/>\n<time datetime=\"2026-01-11\">11 \u0399\u03b1\u03bd\u03bf\u03c5\u03b1\u03c1\u03af\u03bf\u03c5 2026<\/time><\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0 18px;\"><strong>\u03a3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7 \u03c0\u03b5\u03c1\u03af\u03bb\u03b7\u03c8\u03b7:<\/strong><br \/>\n\u0397 <strong>\u039b\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a) \u2013 Lp(a)<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03c0\u03bf\u03c5<br \/>\n<strong>\u03b4\u03b5\u03bd \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b1<\/strong> \u03bc\u03b5 \u03c4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1.<br \/>\n\u03a4\u03bf <strong>Inclisiran (Leqvio)<\/strong> \u03b4\u03b5\u03bd \u03c4\u03b7 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9,<br \/>\n\u03b1\u03bb\u03bb\u03ac \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd <strong>LDL<\/strong><br \/>\n\u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 <strong>\u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03c3\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03bd \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf<\/strong><br \/>\n\u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ae Lp(a).<\/div>\n<nav id=\"toc\" style=\"background: #f9fafb; border: 1px solid #e5e7eb; border-radius: 14px; padding: 14px; margin: 16px 0;\" aria-label=\"\u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1\"><strong>\ud83d\udcd1 \u03a0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b1<\/strong><\/p>\n<ol style=\"margin: 10px 0 0 18px; line-height: 1.9;\">\n<li><a style=\"color: #dc2626;\" href=\"#rolos-inclisiran\">\u039f \u03c1\u03cc\u03bb\u03bf\u03c2 \u03c4\u03bf\u03c5 Inclisiran \u03cc\u03c4\u03b1\u03bd \u03b7 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#ti-einai-lpa\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u039b\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a) \u2013 Lp(a)<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#inclisiran-lpa\">\u0395\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf Inclisiran \u03c4\u03b7\u03bd Lp(a);<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#orion-lpa\">\u03a4\u03b9 \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03bf\u03b9 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 ORION<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#pote-inclisiran-lpa\">\u03a0\u03cc\u03c4\u03b5 \u03ad\u03c7\u03b5\u03b9 \u03bd\u03cc\u03b7\u03bc\u03b1 \u03c4\u03bf Inclisiran \u03c3\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ae Lp(a)<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#therapeies-lpa\">\u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c4\u03bf\u03c7\u03b5\u03cd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd Lp(a)<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#ofeli-inclisiran-lpa\">\u039f\u03c6\u03ad\u03bb\u03b7 \u03c4\u03bf\u03c5 Inclisiran \u03c3\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ae Lp(a)<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#summary-lpa-inclisiran\">\u03a3\u03cd\u03bd\u03bf\u03c8\u03b7<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#faq-lpa\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#kleiste-rantevou\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd<\/a><\/li>\n<li><a style=\"color: #dc2626;\" href=\"#bibliografia\">\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/a><\/li>\n<\/ol>\n<\/nav>\n<hr style=\"border: 0; border-top: 2px solid #d1d5db; margin: 14px 0;\" \/>\n<p><!-- ==================== SECTION 1 ==================== --><\/p>\n<h2 id=\"rolos-inclisiran\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">1<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03bf\u03b9\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03c1\u03cc\u03bb\u03bf\u03c2 \u03c4\u03bf\u03c5 Inclisiran \u03cc\u03c4\u03b1\u03bd \u03b7 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7<br \/>\n<\/span><\/h2>\n<p>\u0397 <strong>\u039b\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a) \u2013 Lp(a)<\/strong> \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03ad\u03bd\u03b1\u03bd<br \/>\n<strong>\u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03bf \u03ba\u03b1\u03b9 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/strong>.<br \/>\n\u03a3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 <strong>LDL \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7<\/strong>,<br \/>\n\u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03ce\u03bd\u03c4\u03b1\u03c2 \u03ad\u03bd\u03b1 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b1\u03c1\u03c5\u03bc\u03ad\u03bd\u03bf \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5.<\/p>\n<p>\u03a4\u03bf <strong>Inclisiran (Leqvio)<\/strong> \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c9\u03c2 \u03c3\u03c4\u03cc\u03c7\u03bf \u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 Lp(a),<br \/>\n\u03b1\u03bb\u03bb\u03ac \u03b4\u03c1\u03b1 \u03c3\u03c4\u03b7 <strong>PCSK9<\/strong> \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ac \u03c4\u03b7\u03bd LDL,<br \/>\n\u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03c0\u03bf\u03c5 <strong>\u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03bd \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf<\/strong><br \/>\n\u03cc\u03c4\u03b1\u03bd \u03b7 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c8\u03b7\u03bb\u03ae.<\/p>\n<p>\u039c\u03b5 \u03b1\u03c0\u03bb\u03ac \u03bb\u03cc\u03b3\u03b9\u03b1:<br \/>\n<strong>\u03cc\u03c4\u03b1\u03bd \u03b4\u03b5\u03bd \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bc\u03b5 \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03bf\u03c5\u03bc\u03b5 \u03ac\u03bc\u03b5\u03c3\u03b1 \u03c4\u03b7\u03bd Lp(a), \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03c5\u03bc\u03b5 \u03cc\u03c3\u03bf \u03c4\u03bf \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c4\u03b7\u03bd LDL<\/strong>.<br \/>\n\u03a3\u03b5 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf, \u03c4\u03bf Inclisiran \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03ad\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c0\u03b9\u03bf \u03b9\u03c3\u03c7\u03c5\u03c1\u03ac \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b1 \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03b1.<\/p>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03bd\u03cc\u03b7\u03bc\u03b1:<\/strong><br \/>\n\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 <strong>\u03c5\u03c8\u03b7\u03bb\u03ae Lp(a)<\/strong>, \u03ba\u03ac\u03b8\u03b5 \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 LDL<br \/>\n\u03bc\u03b5\u03c4\u03b1\u03c6\u03c1\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 <strong>\u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03bc\u03c6\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03ba\u03bf\u03cd<\/strong>.<\/div>\n<p>\u0393\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c4\u03bf\u03c5 Inclisiran, \u03c4\u03bf\u03bd \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2,<br \/>\n\u03c4\u03b7 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b9\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5, \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf \u03ba\u03cd\u03c1\u03b9\u03bf \u03ac\u03c1\u03b8\u03c1\u03bf:\ud83d\udc49 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/inclisiran-leqvio\/\" target=\"_blank\" rel=\"noopener\">Inclisiran (Leqvio) \u2013 \u03a0\u03bb\u03ae\u03c1\u03b7\u03c2 \u039f\u03b4\u03b7\u03b3\u03cc\u03c2.<\/a><\/p>\n<p><!-- ==================== SECTION 2 ==================== --><\/p>\n<h2 id=\"ti-einai-lpa\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">2<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u039b\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a) \u2013 Lp(a)<br \/>\n<\/span><\/h2>\n<p>\u0397 <strong>\u039b\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a)<\/strong>, \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae \u03c9\u03c2 <strong>Lp(a)<\/strong>,<br \/>\n\u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03bc\u03cc\u03c1\u03b9\u03bf \u03c0\u03bf\u03c5 \u03bc\u03bf\u03b9\u03ac\u03b6\u03b5\u03b9 \u03b4\u03bf\u03bc\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b7\u03bd <strong>LDL \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7<\/strong>,<br \/>\n\u03b1\u03bb\u03bb\u03ac \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03c4\u03b7\u03bd <strong>\u03b1\u03c0\u03bf\u03bb\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a)<\/strong>.<br \/>\n\u0391\u03c5\u03c4\u03ae \u03b7 \u03b4\u03bf\u03bc\u03ae \u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac <strong>\u03b9\u03c3\u03c7\u03c5\u03c1\u03ac \u03b1\u03b8\u03b7\u03c1\u03bf\u03b3\u03cc\u03bd\u03bf \u03ba\u03b1\u03b9 \u03b8\u03c1\u03bf\u03bc\u03b2\u03bf\u03b3\u03cc\u03bd\u03bf<\/strong>.<\/p>\n<p>\u0397 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 <strong>\u03c3\u03c7\u03b5\u03b4\u03cc\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7<\/strong><br \/>\n\u03ba\u03b1\u03b9 <strong>\u03b4\u03b5\u03bd \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac<\/strong> \u03bc\u03b5 \u03b4\u03af\u03b1\u03b9\u03c4\u03b1, \u03ac\u03c3\u03ba\u03b7\u03c3\u03b7 \u03ae \u03c4\u03b9\u03c2 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2<br \/>\n\u03c5\u03c0\u03bf\u03bb\u03b9\u03c0\u03b9\u03b4\u03b1\u03b9\u03bc\u03b9\u03ba\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2.<\/p>\n<ul>\n<li>\u0391\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf <strong>\u03b5\u03bc\u03c6\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03bf\u03c2<\/strong>, <strong>\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03ba\u03bf\u03cd<\/strong> \u03ba\u03b1\u03b9 <strong>\u03b1\u03bf\u03c1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c4\u03ad\u03bd\u03c9\u03c3\u03b7\u03c2<\/strong><\/li>\n<li>\u0394\u03c1\u03b1 \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd LDL<\/li>\n<\/ul>\n<div style=\"background: #f8fafc; border-left: 4px solid #b70000; border-radius: 10px; padding: 12px 14px; margin: 14px 0;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03cc\u03c1\u03b9\u03bf:<\/strong><br \/>\n\u03a4\u03b9\u03bc\u03ad\u03c2 <strong>Lp(a) &gt; 50 mg\/dL<\/strong> \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9<br \/>\n<strong>\u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/strong>.<\/div>\n<p><!-- ==================== SECTION 3 ==================== --><\/p>\n<h2 id=\"inclisiran-lpa\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">3<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0395\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf Inclisiran \u03c4\u03b7\u03bd Lp(a);<br \/>\n<\/span><\/h2>\n<p>\u03a3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b5\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 <strong>ORION<\/strong>,<br \/>\n\u03c4\u03bf <strong>Inclisiran<\/strong> \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af<br \/>\n<strong>\u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 LDL<\/strong>,<br \/>\n\u03b1\u03bb\u03bb\u03ac <strong>\u03b4\u03b5\u03bd \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 Lp(a)<\/strong>.<\/p>\n<ul>\n<li>LDL: <strong>\u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 50\u201352%<\/strong><\/li>\n<li>Lp(a): <strong>\u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ae 0\u20133%<\/strong> (\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03b1\u03bc\u03b5\u03bb\u03b7\u03c4\u03ad\u03b1)<\/li>\n<\/ul>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 14px 0;\"><strong>\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b1\u03c5\u03c4\u03cc:<\/strong><br \/>\n\u03a4\u03bf Inclisiran <strong>\u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 Lp(a)<\/strong>,<br \/>\n\u03b1\u03bb\u03bb\u03ac \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd LDL<br \/>\n<strong>\u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf<\/strong><br \/>\n\u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ae Lp(a).<\/div>\n<p><!-- ==================== SECTION 4 ==================== --><\/p>\n<h2 id=\"orion-lpa\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">4<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a4\u03b9 \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03bf\u03b9 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 ORION \u03b3\u03b9\u03b1 \u03c4\u03b7 Lp(a)<br \/>\n<\/span><\/h2>\n<p>\u039f\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ad\u03c2 <strong>ORION-9, ORION-10 \u03ba\u03b1\u03b9 ORION-11<\/strong><br \/>\n\u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b1\u03bd \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 Inclisiran \u03c4\u03cc\u03c3\u03bf \u03c3\u03c4\u03b7 <strong>LDL<\/strong><br \/>\n\u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 <strong>Lp(a)<\/strong>.<\/p>\n<ul>\n<li>\u0397 LDL \u03bc\u03b5\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 <strong>\u226550%<\/strong><\/li>\n<li>\u0397 Lp(a) \u03bc\u03b5\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 \u03bc\u03cc\u03bd\u03bf <strong>0\u20133%<\/strong><\/li>\n<li><strong>\u0394\u03b5\u03bd \u03c5\u03c0\u03ae\u03c1\u03be\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 Lp(a)<\/strong><\/li>\n<\/ul>\n<p>\u03a3\u03c5\u03bd\u03b5\u03c0\u03ce\u03c2, \u03c4\u03bf Inclisiran <strong>\u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 Lp(a)<\/strong>,<br \/>\n\u03b1\u03bb\u03bb\u03ac \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7 <strong>\u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03bf\u03cd \u03b1\u03b8\u03b7\u03c1\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5 \u03c6\u03bf\u03c1\u03c4\u03af\u03bf\u03c5<\/strong><br \/>\n\u03cc\u03c4\u03b1\u03bd \u03b7 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c8\u03b7\u03bb\u03ae.<br \/>\n<!-- ==================== SECTION 5 ==================== --><\/p>\n<h2 id=\"pote-inclisiran-lpa\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">5<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03cc\u03c4\u03b5 \u03ad\u03c7\u03b5\u03b9 \u03bd\u03cc\u03b7\u03bc\u03b1 \u03c4\u03bf Inclisiran \u03cc\u03c4\u03b1\u03bd \u03b7 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c8\u03b7\u03bb\u03ae<br \/>\n<\/span><\/h2>\n<p>\u0397 \u03c5\u03c8\u03b7\u03bb\u03ae <strong>Lp(a)<\/strong> \u03b1\u03c0\u03cc \u03bc\u03cc\u03bd\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf,<br \/>\n\u03cc\u03bc\u03c9\u03c2 \u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03b5\u03ba\u03c4\u03bf\u03be\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ba\u03b1\u03b9<br \/>\n<strong>\u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 LDL \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7<\/strong>.<\/p>\n<ul>\n<li><strong>LDL &gt; 100 mg\/dL<\/strong><\/li>\n<li><strong>Lp(a) &gt; 50 mg\/dL<\/strong><\/li>\n<\/ul>\n<p>\u03a3\u03b5 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03c3\u03b5\u03bd\u03ac\u03c1\u03b9\u03bf, \u03b7 <strong>\u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 LDL<\/strong> \u03bc\u03b5 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03c4\u03bf<br \/>\n<strong>Inclisiran<\/strong> \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03b5\u03b9 \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac<br \/>\n<strong>\u03c4\u03bf \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03b1\u03b8\u03b7\u03c1\u03bf\u03b3\u03cc\u03bd\u03bf \u03c6\u03bf\u03c1\u03c4\u03af\u03bf<br \/>\n<\/strong>,<br \/>\n\u03c0\u03b1\u03c1\u03cc\u03c4\u03b9 \u03b7 Lp(a) \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7.<\/p>\n<p>\u0393\u03b9\u03b1 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc, \u03c4\u03b7 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b9\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 Inclisiran,<br \/>\n\u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf \u03ba\u03cd\u03c1\u03b9\u03bf \u03ac\u03c1\u03b8\u03c1\u03bf:\ud83d\udc49 <a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/inclisiran-leqvio\/\" target=\"_blank\" rel=\"noopener\">Inclisiran (Leqvio) \u2013 \u03a0\u03bb\u03ae\u03c1\u03b7\u03c2 \u039f\u03b4\u03b7\u03b3\u03cc\u03c2<br \/>\n<\/a><\/p>\n<p><!-- ==================== SECTION 6 ==================== --><\/p>\n<h2 id=\"therapeies-lpa\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">6<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a0\u03bf\u03b9\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03c3\u03c4\u03bf\u03c7\u03b5\u03cd\u03bf\u03c5\u03bd \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03c4\u03b7 Lp(a)<br \/>\n<\/span><\/h2>\n<ol>\n<li><strong>Pelacarsen<\/strong> (antisense oligonucleotide) \u2013 \u03c5\u03c0\u03cc \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 (Lp(a)HORIZON)<\/li>\n<li><strong>Olpasiran<\/strong> (siRNA) \u2013 \u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7<\/li>\n<li><strong>Lomitapide<\/strong> \u2013 \u03c3\u03b5 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bc\u03bf\u03c1\u03c6\u03ad\u03c2 FH \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ae Lp(a)<\/li>\n<li><strong>Lipoprotein apheresis<\/strong> \u2013 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03cd \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2<\/li>\n<\/ol>\n<div style=\"background: #f8fafc; border-left: 4px solid #2563eb; border-radius: 10px; padding: 12px 14px; margin: 14px 0;\"><strong>\u03a3\u03b7\u03bc\u03b5\u03af\u03c9\u03c3\u03b7:<\/strong><br \/>\n\u039f\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03b2\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7<br \/>\n\u03ba\u03b1\u03b9 <strong>\u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03c1\u03bf\u03c5\u03c4\u03af\u03bd\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03ac\u03be\u03b7<\/strong>.<\/div>\n<p><!-- ==================== SECTION 7 ==================== --><\/p>\n<h2 id=\"ofeli-inclisiran-lpa\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">7<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0393\u03b9\u03b1\u03c4\u03af \u03c4\u03bf Inclisiran \u03ad\u03c7\u03b5\u03b9 \u03b1\u03be\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd \u03b7 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7<br \/>\n<\/span><\/h2>\n<ul>\n<li>\u039c\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 <strong>LDL<\/strong>, \u03c4\u03bf\u03bd \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b9\u03bc\u03bf \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/li>\n<li>\u0394\u03b5\u03bd \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 <strong>Lp(a)<\/strong><\/li>\n<li>\u0388\u03c7\u03b5\u03b9 <strong>\u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae \u03ba\u03b1\u03b9 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03b4\u03c1\u03ac\u03c3\u03b7<\/strong><\/li>\n<li>\u0394\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03c3\u03c5\u03bc\u03bc\u03cc\u03c1\u03c6\u03c9\u03c3\u03b7<\/li>\n<\/ul>\n<p>\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 <strong>\u03c5\u03c8\u03b7\u03bb\u03ae Lp(a)<\/strong>, \u03c4\u03bf Inclisiran \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af<br \/>\n\u03c9\u03c2 <strong>\u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03bf \u03bc\u03b5\u03af\u03c9\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03bf\u03cd \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/strong><br \/>\n\u03bc\u03ad\u03c3\u03c9 \u03c4\u03b7\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03c4\u03ce\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 LDL.<\/p>\n<p><!-- ==================== SECTION 8 ==================== --><\/p>\n<h2 id=\"summary-lpa-inclisiran\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">8<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03cd\u03bd\u03bf\u03c8\u03b7 \u03b3\u03b9\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ae Lp(a)<br \/>\n<\/span><\/h2>\n<p>\u0397 <strong>Lp(a)<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc\u03c2 \u03b1\u03bb\u03bb\u03ac \u03b4\u03cd\u03c3\u03ba\u03bf\u03bb\u03b1 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b9\u03bc\u03bf\u03c2<br \/>\n\u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5.<br \/>\n\u039c\u03ad\u03c7\u03c1\u03b9 \u03bd\u03b1 \u03c5\u03c0\u03ac\u03c1\u03be\u03bf\u03c5\u03bd \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2,<br \/>\n\u03b7 <strong>\u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 LDL<\/strong><br \/>\n\u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c4\u03b7\u03bd \u03c0\u03b9\u03bf \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae.<\/p>\n<p>\u03a3\u03b5 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf,<br \/>\n\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03c4\u03bf <strong>Inclisiran<\/strong> \u03c0\u03b1\u03af\u03b6\u03bf\u03c5\u03bd<br \/>\n<strong>\u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/strong>.<br \/>\n<!-- ==================== SECTION 9 ==================== --><\/p>\n<h2 id=\"faq-lpa\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">9<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b5\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2 \u03b3\u03b9\u03b1 Lp(a) \u03ba\u03b1\u03b9 \u03c3\u03cd\u03b3\u03c7\u03c1\u03bf\u03bd\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2<br \/>\n<\/span><\/h2>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c5\u03c8\u03b7\u03bb\u03ae Lp(a);<\/summary>\n<p>\u0397 Lp(a) &gt;50 mg\/dL \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03bf \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1, \u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03b1\u03bf\u03c1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03ad\u03bd\u03c9\u03c3\u03b7.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03b9\u03c9\u03b8\u03b5\u03af \u03b7 Lp(a) \u03bc\u03b5 \u03b4\u03af\u03b1\u03b9\u03c4\u03b1 \u03ae \u03ac\u03c3\u03ba\u03b7\u03c3\u03b7;<\/summary>\n<p>\u038c\u03c7\u03b9. \u0397 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b1\u03c0\u03bf\u03ba\u03c1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c4\u03c1\u03cc\u03c0\u03bf\u03c5 \u03b6\u03c9\u03ae\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03c0\u03bf\u03c5 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd Lp(a);<\/summary>\n<p>\u038c\u03c7\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c3\u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03ac\u03be\u03b7\u00b7 \u03c4\u03b1 pelacarsen \u03ba\u03b1\u03b9 olpasiran \u03b2\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03c1\u03bf\u03c7\u03c9\u03c1\u03b7\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a4\u03b9 \u03c1\u03cc\u03bb\u03bf \u03c0\u03b1\u03af\u03b6\u03b5\u03b9 \u03b7 LDL \u03cc\u03c4\u03b1\u03bd \u03b7 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c8\u03b7\u03bb\u03ae;<\/summary>\n<p>\u0397 LDL \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc\u03c2 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b9\u03bc\u03bf\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b7 \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03ae \u03c4\u03b7\u03c2 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03c4\u03bf Inclisiran \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03cc\u03c4\u03b1\u03bd \u03b7 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7;<\/summary>\n<p>\u039d\u03b1\u03b9, \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd LDL \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03b1\u03b8\u03b7\u03c1\u03bf\u03b3\u03cc\u03bd\u03bf \u03c6\u03bf\u03c1\u03c4\u03af\u03bf, \u03c0\u03b1\u03c1\u03cc\u03c4\u03b9 \u03b4\u03b5\u03bd \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b1 \u03c4\u03b7\u03bd Lp(a).<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a0\u03bf\u03cd \u03bc\u03c0\u03bf\u03c1\u03ce \u03bd\u03b1 \u03b4\u03c9 \u03c0\u03ce\u03c2 \u03b4\u03c1\u03b1 \u03c4\u03bf Inclisiran;<\/summary>\n<p>\u03a3\u03c4\u03bf\u03bd \u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03cc \u03bf\u03b4\u03b7\u03b3\u03cc \u03b5\u03b4\u03ce:<br \/>\n<a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/inclisiran-leqvio\/\" target=\"_blank\" rel=\"noopener\"><br \/>\nInclisiran (Leqvio) \u2013 \u03a0\u03bb\u03ae\u03c1\u03b7\u03c2 \u039f\u03b4\u03b7\u03b3\u03cc\u03c2<br \/>\n<\/a><\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u039a\u03ac\u03b8\u03b5 \u03c0\u03cc\u03c4\u03b5 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03bc\u03b5\u03c4\u03c1\u03b9\u03ad\u03c4\u03b1\u03b9 \u03b7 Lp(a);<\/summary>\n<p>\u0397 Lp(a) \u03bc\u03b5\u03c4\u03c1\u03b9\u03ad\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03b7 \u03b6\u03c9\u03ae, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03ac\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03bf\u03bd \u03c7\u03c1\u03cc\u03bd\u03bf.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u03a0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03cc\u03bb\u03bf\u03b9 \u03bd\u03b1 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd Lp(a);<\/summary>\n<p>\u039f \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c3\u03c5\u03bd\u03b9\u03c3\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03c0\u03c1\u03ce\u03b9\u03bc\u03bf \u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1, \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ae \u03b1\u03bd\u03b5\u03be\u03ae\u03b3\u03b7\u03c4\u03b1 \u03c5\u03c8\u03b7\u03bb\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf.<\/p>\n<\/details>\n<details style=\"margin-bottom: 14px; border: 1px solid #e2e8f0; border-radius: 10px; padding: 12px 14px;\">\n<summary style=\"cursor: pointer; font-weight: 600; font-size: 15px; color: #1d4ed8;\">\u0391\u03bd \u03ad\u03c7\u03c9 \u03c5\u03c8\u03b7\u03bb\u03ae Lp(a), \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b8\u03b1 \u03c0\u03ac\u03b8\u03c9 \u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1;<\/summary>\n<p>\u038c\u03c7\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03b9 \u03b3\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c5\u03c3\u03c4\u03b7\u03c1\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c4\u03b7\u03c2 LDL \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03ac\u03bb\u03bb\u03c9\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5.<\/p>\n<\/details>\n<h2 id=\"kleiste-rantevou\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">10<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd<\/span><\/h2>\n<p><strong>\u0395\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03b9\u03b1\u03c4\u03c1\u03cc \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03cc \u03bc\u03b1\u03c2.<\/strong><br \/>\n\u039c\u03c0\u03bf\u03c1\u03b5\u03af\u03c4\u03b5 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03c3\u03b5\u03c4\u03b5 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd (LDL, Lp(a)) \u03ae \u03bd\u03b1 \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03c9\u03bd \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.<\/p>\n<div style=\"background: #fdf2f2; border: 2px solid #b70000; border-radius: 14px; padding: 18px; text-align: center;\">\n<div><strong>\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd (LDL, Lp(a)) \u03ae \u03b4\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf:<\/strong><\/div>\n<div style=\"display: flex; gap: 10px; justify-content: center; flex-wrap: wrap; margin-top: 10px;\"><a style=\"background: #b70000; color: #fff; padding: 12px 18px; border-radius: 12px; text-decoration: none; font-weight: 600;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"nofollow noopener\">\ud83d\udcd8 \u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2 \u0395\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd<\/a><br \/>\n<a style=\"background: #b70000; color: #fff; padding: 12px 18px; border-radius: 12px; text-decoration: none; font-weight: 600;\" href=\"https:\/\/mikrobiologikolamia.gr\/staging\/about-us\/appointments\/\" target=\"_blank\" rel=\"nofollow noopener\">\ud83d\udcc5 \u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03a1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd \u03a4\u03ce\u03c1\u03b1<\/a><\/div>\n<div style=\"margin-top: 10px; color: #374151;\">\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n<\/div>\n<h2 id=\"bibliografia\" style=\"display: inline-flex; align-items: center; gap: 12px; margin: 26px 0 10px;\"><span style=\"width: 36px; height: 36px; display: inline-flex; align-items: center; justify-content: center; transform: rotate(45deg); background: linear-gradient(180deg,#f1f5f9,#9ca3af); border-radius: 10px; box-shadow: 0 6px 14px rgba(17,24,39,.18), inset 0 1px 0 rgba(255,255,255,.65), inset 0 -1px 0 rgba(17,24,39,.10);\"><br \/>\n<span style=\"transform: rotate(-45deg); font-size: 14px; font-weight: 800; color: #111827;\">11<\/span><br \/>\n<\/span><br \/>\n<span style=\"font-size: 24px; font-weight: 900; color: #111827;\">\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/span><\/h2>\n<div style=\"font-size: 14px; line-height: 1.45;\">\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 10px;\">1. Ray KK et al. <em>Inclisiran in patients with atherosclerotic cardiovascular disease (ORION-10\/11).<\/em> NEJM 2020;382:1507-1519.<br \/>\n<a href=\"https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/\" target=\"_blank\" rel=\"noopener\">https:\/\/mikrobiologikolamia.gr\/staging\/katalogos-eksetaseon\/<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 10px;\">2. Raal FJ et al. <em>Inclisiran for heterozygous familial hypercholesterolemia (ORION-9).<\/em> NEJM 2020;382:1520-1530.<br \/>\n<a href=\"https:\/\/www.nejm.org\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.nejm.org<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 10px;\">3. O\u2019Donoghue ML et al. <em>PCSK9 inhibition and cardiovascular risk in patients with elevated Lp(a).<\/em> JAMA Cardiology 2022.<br \/>\n<a href=\"https:\/\/jamanetwork.com\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/jamanetwork.com<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 10px;\">4. Tsimikas S. <em>PCSK9 inhibitors beyond LDL reduction.<\/em> J Am Coll Cardiol 2023;81:502-516.<br \/>\n<a href=\"https:\/\/www.jacc.org\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.jacc.org<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 10px;\">5. Catapano AL et al. <em>2023 ESC\/EAS Guidelines for the management of dyslipidaemias.<\/em> Eur Heart J 2023.<br \/>\n<a href=\"https:\/\/academic.oup.com\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/academic.oup.com<\/a><\/div>\n<div style=\"border-left: 3px solid #e5e7eb; padding-left: 10px; margin-bottom: 14px;\">6. Banach M et al. <em>Inclisiran and future PCSK9 therapies.<\/em> Curr Atheroscler Rep 2024;26(1):12-24.<br \/>\n<a href=\"https:\/\/link.springer.com\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/link.springer.com<\/a><\/div>\n<\/div>\n<p><!-- \u0395\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03bc\u03ad\u03bb\u03b5\u03b9\u03b1 --><\/p>\n<div style=\"background: #f1f5f9; border-left: 4px solid #2563eb; padding: 10px 14px; border-radius: 8px; margin-top: 12px;\"><strong style=\"color: #1d4ed8;\">\u0395\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03bc\u03ad\u03bb\u03b5\u03b9\u03b1:<\/strong><br \/>\n\u0394\u03c1. \u03a0\u03b1\u03bd\u03c4\u03b5\u03bb\u03ae\u03c2 \u0391\u03bd\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03cc\u03c0\u03bf\u03c5\u03bb\u03bf\u03c2, \u0399\u03b1\u03c4\u03c1\u03cc\u03c2 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u2013 \u0392\u03b9\u03bf\u03c0\u03b1\u03b8\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2<br \/>\n\u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u039b\u03b1\u03bc\u03af\u03b1\u03c2, \u0388\u03c3\u03bb\u03b9\u03bd 19, \u039b\u03b1\u03bc\u03af\u03b1 35100<br \/>\n\ud83d\udcde +30-22310-66841 \u2022 \u0394\u03b5\u03c5\u03c4\u03ad\u03c1\u03b1\u2013\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae 07:00\u201313:30<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u039b\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a) \u2013 Lp(a) \u03ba\u03b1\u03b9 Inclisiran (Leqvio): \u03a0\u03ce\u03c2 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bf \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc\u03c2 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b5\u03bd\u03b7\u03bc\u03ad\u03c1\u03c9\u03c3\u03b7: 11 \u0399\u03b1\u03bd\u03bf\u03c5\u03b1\u03c1\u03af\u03bf\u03c5 2026 \u03a3\u03cd\u03bd\u03c4\u03bf\u03bc\u03b7 \u03c0\u03b5\u03c1\u03af\u03bb\u03b7\u03c8\u03b7: \u0397 \u039b\u03b9\u03c0\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7(a) \u2013 Lp(a) \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03c3\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1. \u03a4\u03bf Inclisiran (Leqvio) \u03b4\u03b5\u03bd \u03c4\u03b7 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9, \u03b1\u03bb\u03bb\u03ac \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7\u03bd LDL \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03c3\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03bd \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":8981,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2541],"tags":[103,43,225,2805,41,222,94,144,217],"class_list":["post-2796","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-odigoi-farmakon","tag-inclisiran","tag-ldl","tag-leqvio","tag-lipoprotein-a","tag-lpa","tag-pcsk9","tag-dyslipidaimia","tag-kardiangeiakos-kindynos","tag-cholisteroli"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/2796","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/comments?post=2796"}],"version-history":[{"count":14,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/2796\/revisions"}],"predecessor-version":[{"id":8984,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/posts\/2796\/revisions\/8984"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media\/8981"}],"wp:attachment":[{"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/media?parent=2796"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/categories?post=2796"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mikrobiologikolamia.gr\/staging\/wp-json\/wp\/v2\/tags?post=2796"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}